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焦化废水反渗透膜污染特性研究

湘潭大学学报（自然科学版） 2022年第1期44卷 73-81页

作者：袁意魏天祥黄增显余逸飞吴亚辉熊雅玲周琼芝沈健段锋苗宝宝湘潭大学环境与资源学院湖南湘潭411105 中国科学院过程工程研究所环境技术与工程研究部北京市过程污染控制工程技术研究中心北京100190 河南中科康仑环保科技有限公司河南平顶山450003

反渗透(RO)脱盐工艺对实现焦化废水再生利用具有重要意义,而膜污堵制约了RO工艺进一步发展.对河南某焦化废水膜处理车间的膜污堵特性与进水水质特征进行研究.将RO进水按亲/疏水性及碱/酸/中性分为六个组分,分别进行膜污染和清洗实验,用... 详细信息

反渗透(RO)脱盐工艺对实现焦化废水再生利用具有重要意义,而膜污堵制约了RO工艺进一步发展.对河南某焦化废水膜处理车间的膜污堵特性与进水水质特征进行研究.将RO进水按亲/疏水性及碱/酸/中性分为六个组分,分别进行膜污染和清洗实验,用比通量表征膜污堵程度并与废水DOC、多糖、腐殖质、Ca、Mg、Si等成分含量做线性回归分析.结果表明,膜污染主要表现为有机物-无机物复合污染,膜污染层为硅镁配合物、硫酸钙及其水合物通过有机物黏合堆砌形成,有机污染物为蛋白质、多糖等物质,无机离子中Si(R^(2)=0.754,P=0.050)对膜污染影响效果显著.比通量变化用Ca、Mg、Si、腐殖质复合污染解释(R^(2)=0.999,P=0.072),得到回归方程:J_(N)×10^(-2)=2.73×C_(1)-3.41×C_(2)-17.49×C_(3)-5.92×C_(4)+89.72(J_(N)为比通量,C_(1)为Ca浓度、C_(2)为Mg浓度、C_(3)为Si浓度、C_(4)为腐殖质类指数SUVA_(254)).

关键词：焦化废水反渗透工艺膜污染树脂分馏

A Multilayered Magnetoelectric Transmitter with Suppressed Nonlinearity for Portable VLF Communication

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Research 2024年第2期2023卷 553-563页

作者： Zhaoqiang Chu Zhineng Mao Kaixin Song Shizhan Jiang Shugang Min wei Dan Chenyuan Yu Meiyu Wu Yinghui Ren Zhichao Lu Jie Jiao tianxiang Nan Shuxiang Dong Qingdao Innovation and Development Base Harbin Engineering UniversityQingdao 266071China College of Underwater Acoustics Engineering Harbin Engineering UniversityHarbin 150001China Songshan Lake Materials Laboratory DongguanGuangdong 523808 China Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 201800China School of Integrated Circuits and Beijing National Research Center for Information Science and Technology(BNRist) Tsinghua UniversityBeijing 100084China College of Engineering Peking UniversityBeijing 100871China

Acoustically actuated magnetoelectric(ME)antenna based on the efficient oscillation of magnetic dipoles has recently been considered as a promising solution for portable very-low-frequency ***,the severe nonlinear dynamic behavior in the case of strong-field excitation results in insufficient radiation capability and poor communication performance for a conventional ME *** this work,we propose to suppress the nonlinearity of an ME antenna by neutralizing the spring-hardening effect in amorphous Metglas and the spring-softening effect in piezoelectric ceramics through an ME multilayered transmitter(ME-MLTx)*** a driving voltage of 50 V_(pp)at the resonance frequency of 21.2 kHz,a magnetic flux density as high as 108 fT at a distance of 100 m is produced from a single *** addition,ME-MLTx performs a decreased mechanical quality factor(Q_(m))less than 40.65,and,thus,a broadened bandwidth of 500 Hz is ***,a communication link transmitting binary American Standard Code for Information Interchange-coded message is built,which allows for an error-free communication with a distance of 18 m and a data rate of 300 bit/s in the presence of heavy environment *** communication distance can be further estimated over 100 m when using a femtotesla-class-inductive magnetic field *** obtained results are believed to bring ME antennas one step closer to being applicable in very-low-frequency communications.

关键词： closer nonlinearity inductive

Lignin-assisted construction of sub-10 nm supramolecular self-assembly for photothermal immunotherapy and potentiating anti-PD-1 therapy against primary and distant breast tumors

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Asian Journal of Pharmaceutical Sciences 2022年第5期17卷 713-727页

作者： Xudong Fan tianxiang Yue Aidi Liu Xiaowei Xie weixiang Fang Yinghui wei Hangsheng Zheng Hongyue Zheng Meiqi Zhou Jigang Piao Fanzhu Li School of Pharmaceutical Sciences Zhejiang Chinese Medical UniversityHangzhou 310053China Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province School of Pharmaceutical SciencesZhejiang Chinese Medical UniversityHangzhou 310053China Libraries of Zhejiang Chinese Medical University Zhejiang Chinese Medical UniversityHangzhou 310053China Department of Breast Surgery Key Laboratory of Cancer Prevention and InterventionChina National Ministry of EducationSecond Hospital of ZhejiangUniversity College of MedicineHangzhou 310009China Academy of Chinese Medical Sciences Zhejiang Chinese Medical UniversityHangzhou 310053China

Photothermal therapy(PTT)has brought hope for cancer treatments,with hyperthermia-induced immunogenic cell death(ICD),which is a critical part of therapeutically induced antitumor immune *** immune stimulation response in PTT is the primary reason for incomplete tumor ablation,therefore demonstrating urgent requirements for ICD ***,a sub-10 nm supramolecular nanoassembly was formed by coassembly of clinically approved aluminum adjuvant and commonly used indocyanine green(ICG)under the assistance of lignosulfonate(LS,a green and sustainable multifunctional lignin derivative)for localized photothermal-immunotherapy of breast *** overall results revealed that LS-Al-ICG is capable of inducing amplified ICD,efficiently eliciting solid immune responses through dendritic cells(DCs)activation and cytotoxic T-cell responses initiation for tumor ***,anti-PD-1 therapy blocked the PD-1 pathway and led to remarkable anti-tumor efficacy against laser-irradiated primary tumors and distant tumors by potentiating systemic tumor specific T cell *** results of this study demonstrate a handy and extensible approach for engineering green natural lignin nanoparticles for cancer immunotherapy,which shows promise for delivering other therapeutics in biomedical applications.

关键词： Lignin Supramolecular self-assembly Photothermal-immunotherapy Anti-PD-1

IODP385-U1550单斜辉石指示加利福尼亚湾瓜伊马斯盆地海底扩张早期MORB深部结晶作用

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大地构造与成矿学 2023年第6期47卷 1345-1362页

作者：张天翔颉炜河海大学自然资源部海洋灾害预报技术重点实验室江苏南京210024 河海大学海洋学院江苏南京210024

洋中脊玄武岩(MORB)分离结晶深度是控制其成分变化以及洋壳增生的关键因素之一。为了探究海底扩张早期洋中脊岩浆分离结晶的最深深度,本文对国际大洋发现计划(IODP)385航次在加利福尼亚湾瓜伊马斯盆地U1550站位获得的玄武质岩浆岩样品... 详细信息

洋中脊玄武岩(MORB)分离结晶深度是控制其成分变化以及洋壳增生的关键因素之一。为了探究海底扩张早期洋中脊岩浆分离结晶的最深深度,本文对国际大洋发现计划(IODP)385航次在加利福尼亚湾瓜伊马斯盆地U1550站位获得的玄武质岩浆岩样品进行了详细的岩石学和矿物学研究。U1550站位岩心主要由拉斑玄武岩、辉绿岩以及辉绿岩捕虏体组成,其单斜辉石主要为普通辉石,透辉石次之。单斜辉石-熔体温压计计算得出U1550玄武岩单斜辉石结晶温度(1126~1170℃,误差±45℃)和压力(–0.5~5.4kbar,误差±1.4kbar)相对辉绿岩及辉绿岩捕虏体单斜辉石(1158~1212℃,误差±45℃;1.6~5.9kbar,误差±1.4kbar)均较低,结晶深度(0~17.8km)相对后者(5.3~19.5km)较浅。与全球其他洋脊段MORB单斜辉石相比, U1550单斜辉石具有更陡峭的冷却轨迹。综合研究表明,在海底扩张早期,扩张速率很可能均为慢速扩张,其岩浆结晶深度可超过10 km。这暗示着在海底扩张早期岩石圈地幔厚度很厚,地幔部分熔融产生岩浆的终止深度也相对更深,导致岩浆结晶深度深,部分岩浆难以抵达浅部洋壳。但不同于慢速-超慢速扩张成熟洋脊段,海底扩张早期深部岩浆房岩浆供给可能并不匮乏,而是这些岩浆房很可能位于更深的部位。

关键词： IODP 385 加利福尼亚湾海底扩张早期单斜辉石岩浆深部结晶

孕妇血清维生素A、E水平与子痫前期的相关性研究

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中国医学创新 2018年第8期15卷 1-4页

作者：赵志英崔世红李根霞张林东刘萍萍职云晓余洁刘金金吕晓峰魏天祥郑州大学第三附属医院河南郑州450052

目的:探讨孕妇血清维生素A、E水平与子痫前期的相关性。方法:选取2015年11月-2017年5月在郑州大学第三附属医院产检并于12~20周检测血清维生素A、E水平的1 451例孕妇为研究对象,其中子痫前期组(PE组)211例,健康对照组1 240例,采用高效... 详细信息

目的:探讨孕妇血清维生素A、E水平与子痫前期的相关性。方法:选取2015年11月-2017年5月在郑州大学第三附属医院产检并于12~20周检测血清维生素A、E水平的1 451例孕妇为研究对象,其中子痫前期组(PE组)211例,健康对照组1 240例,采用高效液相色谱法检测血清中维生素A、E的浓度,分娩后收集临床资料并进行分析。结果:(1)单因素分析。PE组孕妇血清维生素E水平高于健康对照组,两组血清维生素E水平、产前BMI、增幅BMI、年龄比较差异均有统计学意义(P0.05)。(2)多因素Logistic回归分析。对单因素分析具有统计学意义的因素进行分析,结果孕妇血清维生素E水平[OR=1.161,95%CI(1.122,1.201),P=0.000]、产前BMI[OR=1.287,95%CI(1.221,1.385),P=0.000]和年龄[0R=2.374,95%CI(1.621,3.475),P=0.000]均为子痫前期发病的独立危险因素。结论:孕妇血清维生素E水平与子痫前期具有一定相关性,且先于临床症状出现之前发生异常,可能成为子痫前期的一项预测指标。

关键词：子痫前期氧化应激维生素A 维生素E

Highly sensitive integrated flexible tactile sensors with piezoresistive Ge2Sb2Te5 thin films

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npj Flexible Electronics 2018年第1期2卷 137-142页

作者： Zhiguang Wang Cunzheng Dong Xinjun Wang Menghui Li tianxiang Nan Xianfeng Liang Huaihao Chen Yuyi wei Haomiao Zhou Mohsen Zaeimbashi Syd Cash Nian-Xiang Sun Department of Electrical and Computer Engineering Northeastern UniversityBostonMA 02115USA Electronic Materials Research Laboratory Key Laboratory of the Ministry of Education&International Center for Dielectric ResearchSchool of Electronic and Information EngineeringXi’an Jiaotong University710049 Xi’anChina Department of Neurology Massachusetts General HospitalBostonMA 02114USA College of Information Engineering China Jiliang University310018 HangzhouChina

Flexible tactile sensor has been extensively investigated as a key component for emerging electronics applications such as robotics,wearable devices,computer hardware,and security *** sensors based on various one-dimensional materials have been widely ***,precise control of the direction and distribution of these nanomaterials remains a great challenge,and it has been difficult to scale down the ***,we introduce highly sensitive integrated flexible tactile sensors based on uniform phase-change Ge_(2)Sb_(2)Te_(5)(GST)thin films that can scale device size down,at least,to micrometer *** piezoresistive effect has been observed in GST-based sensors,showing a giant gauge factor of 338.A proof of concept 5×5 sensor array functioning as a touch panel has been ***,the flexible GST tactile sensor has been utilized for monitoring of radial artery *** addition to the well-known tunable electrical and optical properties,the piezoresistive GST films provide a versatile platform for the integration of sensing,recording,and displaying functions.

关键词： Ge_(2)Sb_(2)Te_(5) hardware Highly

RP11-789C1.1 inhibits gastric cancer cell proliferation and accelerates apoptosis via the ATR/CHK1 signaling pathway

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Chinese Medical Journal 2024年第15期137卷 1835-1843页

作者： Wenwei Liu wei Feng Yongxin Zhang tianxiang Lei Xiaofeng Wang Tang Qiao Zehong Chen Wu Song Digestive Diseases Center The Seventh Affiliated Hospital of Sun Yat-sen UniversityShenzhenGuangdong 518000China Department of Gastrointestinal Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510080China Laboratory of General Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510080China Department of Gastrointestinal Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510630China

Background:Long non-coding RNAs(lncRNAs)plays an important role in the progression of gastric cancer(GC).Their involvement ranges from genetic regulation to cancer ***,the mechanistic roles of RP11-789C1.1 in GC are not fully ***:We identified the expression of lncRNA RP11-789C1.1 in GC tissues and cell lines by real-time fluorescent quantitative polymerase chain reaction.A series of functional experiments revealed the effect of RP11-789C1.1 on the proliferation of GC *** vivo experiments verified the effect of RP11-789C1.1 on the biological behavior of a GC cell *** pull-down unveiled RP11-789C1.1 interacting *** blot analysis indicated the downstream pathway changes of RP11-789C1.1,and an oxaliplatin dosing experiment disclosed the influence of RP11-789C1.1 on the drug sensitivity of ***:Our results demonstrated that RP11-789C1.1 inhibited the proliferation of GC cells and promoted the apoptosis of GC ***,RP11-789C1.1 inhibited checkpoint kinase 1(CHK1)phosphorylation by binding ataxiatelangiectasia mutated and Rad3 related(ATR),a serine/threonine-specific protein kinase,promoted GC apoptosis,and mediated oxaliplatin ***:In general,we discovered a tumor suppressor molecule RP11-789C1.1 and confirmed its mechanism of action,providing a theoretical basis for targeted GC therapy.

关键词： Long non-coding RNA RP11-789C1.1 Stomach neoplasms ATR CHK1 Oxaliplatin

The Low Energy X-ray telescope (LE) onboard the Insight-HXMT astronomy satellite

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Science China(Physics,Mechanics & Astronomy) 2020年第4期63卷 49-61页

作者： Yong Chen weiwei Cui wei Li Juan Wang YuPeng Xu FangJun Lul YuSa Wang tianxiang Chen Dawei Han wei Hu Yi Zhang Jia Huo YanJi Yang MaoShun Li Bo Lu ZiLiang Zhang TiPei Li ShuangNan Zhang ShaoLin Xiong Shu Zhang RongFeng Xue XiaoFan Zhao Yue Zhu YuXuan Zhu Hongwei Liu YiJung Yang Fan Zhang Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Department of Physics Tsinghua UniversityBeijing 100084China Department of Education Lu Liang UniversityLuliang 033000China Qian Xuesen Laboratory of Space Technology China Academy of Space TechnologyBeijing 100094China College of Physics Jilin UniversityChangchun 130023China

The Low Energy X-ray telescope(LE) is one of the three main instruments of the Insight-Hard X-ray Modulation Telescope(Insight-HXMT). It is equipped with Swept Charge Device(SCD) sensor arrays with a total geometrical area of 384 cm^2 and an energy band from 0.7 to 13 ke V. In order to evaluate the particle induced X-ray background and the cosmic X-ray background simultaneously, LE adopts collimators to define four types of Field Of Views(FOVs), i.e., 1.6°×6°, 4°×6°, 50°-60°×2°-6 oand the blocked ones which block the X-ray by an aluminum cover. LE is constituted of three detector boxes(LEDs) and an electric control box(LEB) and achieves a good energy resolution of 140 e V@5.9 ke V, an excellent time resolution of 0.98 ms, as well as an extremely low pileup(<1%@18000 cts/s). Detailed performance tests and calibration on the ground have been performed,including energy-channel relation, energy response, detection efficiency and time response.

关键词： LE X-ray telescope SCD collimators

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高山林线变化的更新受限机制研究进展

生态学报 2017年第9期37卷 2858-2868页

作者：沈维张林罗天祥中国科学院青藏高原研究所高寒生态与生物多样性重点实验室北京100101

全球林线位置对气候变暖的响应表现为上升、无变化或下降等截然不同趋势,表明影响林线位置及动态的因子十分复杂,除了较普遍认为的低温调控机制外,还存在其它控制林线位置变化的机制。林线向上迁移开始于种子向林线以上的传播及幼苗在... 详细信息

全球林线位置对气候变暖的响应表现为上升、无变化或下降等截然不同趋势,表明影响林线位置及动态的因子十分复杂,除了较普遍认为的低温调控机制外,还存在其它控制林线位置变化的机制。林线向上迁移开始于种子向林线以上的传播及幼苗在林线以上的定居,这些过程中的限制因子均会影响林线的位移,因此研究更新过程及其限制因子对理解高山林线对气候变化的响应具有重要的科学意义。主要从种子和幼苗两个关键阶段综述高山林线森林更新的研究进展。在种子阶段,夏季积温不足导致种子产量和活力下降,风速过低和浓密灌丛限制种子向林线以上传播,近地表的霜冻/水分胁迫和灌木释放的化感物质会阻碍种子在林线以上萌发。在幼苗阶段,除冬季低温外,生长季内较大的温度日振幅和偶然出现的冻害事件也是导致幼苗死亡的重要原因,而低温环境下的强烈光照引起的低温光抑制会显著降低生长季的光合作用;土壤低温、由土壤温度昼夜变化引起的冻举事件、夏季土壤干旱可能会导致幼苗光合作用下降和死亡率上升;积雪太浅会导致生长季早期幼苗水分供应的严重缺乏,但积雪太深会导致幼苗感染真菌的可能性增加;浓密的灌木和草本植物以及植食动物的啃食也会降低林线以上的幼苗存活率。气候变暖对林线幼苗定居的影响复杂且具有很大不确定性,需要进一步研究气候变暖导致的环境因子变化对林线更新各关键阶段的影响。未来气候变暖无疑会导致生长季起始日提前,结束日推迟,这很可能会增加生长季期间尤其是早期的低温冻害事件,对高山林线树种幼苗的存活具有重要影响。在未来研究中,需要找出定义生长季冻害事件的温度阈值,利用长期气象观测数据分析增温背景下生长季早期冻害事件特征的变化趋势,并进一步开展野外模拟增温实验以深刻理解林线树种的种子萌发和幼苗定居与生长季冻害事件的关系,加强对不同地区林线树种的繁殖策略研究,这将有助于人们进一步理解不同区域林线的形成机制并预测未来气候变化条件下林线的动态变化趋势。

关键词：气候变化生长季冻害事件种子萌发幼苗定居林线动态