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The Effect of Xu’s Influenza Decoction Combined with Oseltamivir on Influenza A:A Propensity Score Matching Study

Clinical Complementary Medicine and Pharmacology 2024年第1期4卷 1-9页

作者： tianxi chen Shuyan Fu Fengyuan Tian Qiushuang Li Hongyu Ling Yijie Lou Jun Tang Hong Zheng Basic Medical School Zhejiang Chinese Medical UniversityHangzhou 310053ZhejiangChina Department of Infectious Diseases First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 31006ZhejiangChina First School of Clinical Medicine Zhejiang Chinese Medical UniversityHangzhou 310053ZhejiangChina Center of Clinical Evaluation and Analysis First Affiliated Hospital of Zhejiang Chinese Medicine UniversityHangzhou 31006ZhejiangChina Department of General Practice First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 31006ZhejiangChina

Background:The resurgence of seasonal influenza virus circulation has been seen in 2021-2022 after the tempo-rary suppression in *** inhibitors(NAIs)are widely applied in the clinical treatment of influenza A despite several ***:To access the efficacy of Xu’s influenza decoction(XID)in combination therapy with oseltamivir for the treatment of influenza ***:In this retrospective cohort study,the eligible participants were diagnosed with influenza A between June 1,2018,and May 30,2022,in the First Affiliated Hospital of Zhejiang Chinese Medical *** to whether Xu’s influenza decoction was applied,patients were divided into two groups:treated with or without *** score matching(PSM)was used to further adjust the covariates between *** primary outcome was to compare time to defervescence via K-M curves,Breslow tests,and Cox regression *** Cox proportional hazards model,a univariate analysis was performed to obtain preliminary results,while a further multivariate analysis was conducted to study the independent factors that influence *** analysis was conducted according to body temperature and time from onset to *** secondary outcome consisted of routine blood and C-reactive protein(CRP),length of stay,and medical ***:A total of 336 patients with influenza A were enrolled in this study(i.e.,163 patients in the XID+oseltamivir group;173 patients in the oseltamivir group).After 1:1 matching via PSM,230 patients meeting the criteria were included in the analysis,with 115 in each *** XID+oseltamivir group had shorter time to defervescence(36 h vs 44 h,P=0.011),shorter length of stay(3 days vs 4 days,P=0.018),and higher defervescence possibility(HR=1.384,95%CI:1.054-1.818).Subgroup analysis indicated that for patients during non-window period(≥48 h)with medium-grade fever(38.1℃-39℃),the XID+oseltamivir combination therapy reduced time to defervescence

关键词： Influenza A Xu’s influenza decoction Oseltamivir Time to defervescence,Cox regression Propensity score matching Cohort study

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mNUTRIC与NRS⁃2002评分对重症病人预后的评估价值比较

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护理研究 2024年第13期38卷 2265-2269页

作者：王伶俐陈天喜冒飒娴丁嘉敏吴敏陈烨南通大学附属医院江苏226000

目的:采用改良危重症营养风险(mNUTRIC)评分和营养风险筛查(NRS⁃2002)评分评估急诊重症监护病房(EICU)病人的营养风险,并比较两种工具对EICU病人28 d死亡率的评估价值。方法:选取2023年2月-5月EICU由急诊入院的病人,从电子医疗记录文件... 详细信息

目的:采用改良危重症营养风险(mNUTRIC)评分和营养风险筛查(NRS⁃2002)评分评估急诊重症监护病房(EICU)病人的营养风险,并比较两种工具对EICU病人28 d死亡率的评估价值。方法:选取2023年2月-5月EICU由急诊入院的病人,从电子医疗记录文件中收集资料,并于病人入住EICU 24 h内采用NRS⁃2002和mNUTRIC评分进行营养评估。采用Cox回归分析探讨营养风险对病人28 d死亡率的影响;绘制受试者工作特征(ROC)曲线评价NRS⁃2002评分、mNUTRIC评分、急性生理与慢性健康状态评分系统Ⅱ(APACHE)Ⅱ评分和序贯器官衰竭(SOFA)评分对28 d死亡率的预测价值。结果:纳入152例病人,mNUTRIC评分筛查出高营养风险(>5分)病人102例,占67.1%;NRS⁃2002评分筛查出高营养风险(≥5分)病人67例,占44.1%;两种评分筛查结果存在不一致性(κ=-0.230)。Cox回归分析显示,mNUTRIC评分(HR=1.782)和SOFA评分(HR=1.186)是EICU危重症病人28 d死亡的危险因素。mNUTRIC评分预测病人28 d死亡率的受试者工作特征(ROC)曲线下面积为0.82[95%CI(0.73,0.90)],最佳临界值为6分,预测价值优于NRS⁃2002评分、APACHEⅡ评分和SOFA评分。结论:mNUTRIC评分可作为EICU重症病人营养风险评估的有效工具,且与病人28 d死亡率相关,但应考虑病人急性阶段和恢复阶段的特征,动态评估营养风险。

关键词：急诊重症监护室 mNUTRIC评分 NRS⁃2002评分营养风险死亡率影响因素预测价值

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d-d Orbital coupling induced by crystal-phase engineering assists acetonitrile electroreduction to ethylamine

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Journal of Energy Chemistry 2024年第2期89卷 216-225,I0006页

作者： Honggang Huang Yao chen Hui Fu Cun chen Hanjun Li Zhe Zhang Feili Lai Shuxing Bai Nan Zhang tianxi Liu Key Laboratory of Synthetic and Biological Colloids Ministry of EducationSchool of Chemical and Material EngineeringJiangnan UniversityWuxi 214122JiangsuChina Department of Chemistry KU LeuvenCelestijnenlaan 200FLeuven 3001Belgium College of Chemistry and Chemical Engineering Qingdao UniversityQingdao 266071ShandongChina

The d-d orbital coupling induced by crystal-phase engineering can effectively adjust the electronic structure of electrocatalysts,thus showing significant catalytic performance,while it has been rarely explored in electrochemical acetonitrile reduction reaction(ARR)to ***,we successfully realize the structural transformation of Pd Cu metallic aerogels(MAs)from face-centered cubic(FCC)to body-centered cubic(BCC)through annealing ***,the BCC Pd Cu MAs exhibit excellent ARR performance with high ethylamine selectivity of 90.91%,Faradaic efficiency of 88.60%,yield rate of 316.0 mmol h^(-1)g^(-1)_(Pd+Cu)and long-term stability for consecutive electrolysis within 20 h at-0.55 V *** hydrogen electrode,outperforming than those of FCC Pd Cu *** the membrane electrode assembly system,BCC Pd Cu MAs also demonstrate excellent ethylamine yield rate of 389.5 mmol h^(-1)g^(-1)_(Pd+Cu).Density functional theory calculation reveals that the d-d orbital coupling in BCC Pd Cu MAs results in an evident correlation effect for the interaction of Pd and Cu sites,which boosts up the Cu sites electronic activities to enhance ARR *** work opens a new route to develop efficient ARR electrocatalysts from the perspective of crystalline structure transformation.

关键词： d-d Orbital coupling Crystal-phase engineering Metallic aerogels Acetonitrile electroreduction reaction Ethylamine

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Plasma-assisted aerogel interface engineering enables uniform Zn^(2+)flux and fast desolvation kinetics toward zinc metal batteries

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Journal of Energy Chemistry 2024年第8期95卷 29-38,I0002页

作者： Zijian Xu Zhenhai Shi Zhan Chang Fan Feng Zhuanyi Liu Dongkun Chu Jianguo Ren Zi-Feng Ma Suli chen tianxi Liu Key Laboratory of Synthetic and Biological Colloids Ministry of Education School of Chemical and Material EngineeringJiangnan UniversityWuxi 214122JiangsuChina Shanghai Electrochemical Energy Devices Research Center Department of Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240China BTR New Material Group Co. LTD.Shenzhen 518000GuangdongChina

The poor reversibility of Zn anodes induced by dendrite growth,surface passivation,and corrosion,severely hinders the practical applicability of Zn metal *** address these issues,a plasmaassisted aerogel(PAG)interface engineering was proposed as efficient ion transport modulator that can simultaneously regulate uniform Zn^(2+)flux and desolvation behavior during battery *** PAG with ordered mesopores acted as an ion sieve to homogenize Zn deposition and accelerate Zn^(2+)flux,which is favorable for corrosion resistance and dendrite ***,the plasma-assisted aerogel with abundant hydrophilic groups can facilitate the desolvation kinetics of Zn^(2+)due to the multiple hydrogen-bonding interaction with the activated water molecules,thus accelerating the Zn^(2+)migration ***,the Zn/Zn cell assembled with PAG-modified separator demonstrates stable plating and stripping behavior(over 1400 h at 1 mA cm^(-2))and high Coulombic efficiency(99.8%at1 mA cm^(-2)after 1100 cycles),and the Zn‖MnO_(2)full cell shows excellent long-term cycling stability and maintains a high capacity of 154.9 mA h g^(-1)after 1000 cycles at 1 A g^(-1).This study provides a feasible approach for the large-scale fabrication of aerogel functionalized separators to realize ultra-stable Zn metal batteries.

关键词： Zn metal batteries Aerogel interface Plasma Zn^(2+)migration kinetics Dendrite growth

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Advancing Energy Systems with In-Situ and Operando Surface-Enhanced Raman Scattering Spectroscopy

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CCS Chemistry 2024年第6期6卷 1403-1421页

作者： Haoming Bao Shi Xuan Leong Jaslyn Ru Ting chen Zhenhai Shi Suli chen Yan Lv tianxi Liu In Yee Phang Xing Yi Ling Key Laboratory of Synthetic and Biological Colloids Ministry of EducationInternational Joint Research Laboratory for Nano Energy CompositesSchool of Chemical and Material EngineeringJiangnan UniversityWuxi 214122 School of Chemistry Chemical Engineering and BiotechnologyNanyang Technological UniversitySingapore 637371

Surface-enhanced Raman scattering spectroscopy(SERS)has emerged as a powerful analytical technique to enable nanoscale investigations of energy *** mini-review focuses on the applications of in-situ and operando SERS in energy-related research,highlighting its unique capabilities and significant contributions to understanding energy storage and conversion *** first introduce the fundamental principles of SERS,key SERS-derived techniques,and commonly employed ***,we delve into the diverse applications of in-situ and operando SERS across various energy systems,encompassing photocatalytic and electrocatalytic systems,fuel cells,solar cells,and ***,we conclude with our perspective on the current challenges and prospects in this *** hope thismini-review serves as an essential overview to guide the design and implementation of in-situ and operando SERS studies of energy systems.

关键词： surface-enhanced Raman scattering spectroscopy in-situ operando energy systems photocatalysis electrocatalysis fuel cells solar cells batteries

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脱盐海参气体射流冲击干燥特性及复水品质

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食品研究与开发 2024年第7期45卷 17-26页

作者：谭卓弘李艾靑陈田玺王松林谢永康李英美刘迎励建荣李学鹏林雅文渤海大学食品科学与工程学院/海洋研究院辽宁锦州121013 辽宁工业大学机械工程与自动化学院辽宁锦州121001 河南省农业科学院农产品加工研究中心河南郑州450002 凌海市达莲海珍品养殖有限责任公司辽宁锦州121209 辽宁凌特食品有限公司辽宁锦州121200

为探索干燥条件对脱盐海参气体射流冲击干燥(air impingement drying,AID)特性的影响,提高海参干制品品质、缩短干燥时间,该文探讨AID温度(50、60、70℃)和气流速度(4、6、8 m/s)对脱盐海参干燥特性、有效水分扩散系数(Deff)、活化能(Ea... 详细信息

为探索干燥条件对脱盐海参气体射流冲击干燥(air impingement drying,AID)特性的影响,提高海参干制品品质、缩短干燥时间,该文探讨AID温度(50、60、70℃)和气流速度(4、6、8 m/s)对脱盐海参干燥特性、有效水分扩散系数(Deff)、活化能(Ea)、干制品复水比和氨基酸含量的影响,用6种常见的干燥模型对干燥曲线进行拟合,并以热风干燥(hot air drying,HAD)为对比。结果表明,风速为6 m/s时,AID不同干燥温度下脱盐海参的干燥时间比HAD 60℃的干燥时间缩短6.67%~33.33%。温度为60℃时,风速对脱盐海参干燥时间影响不显著。不同干燥条件下,复水比无显著性差异。AID海参的氨基酸含量(45.91~47.54 g/100 g)随着温度的升高而升高。相同条件下,AID海参的氨基酸含量比HAD海参增加4.46%。AID脱盐海参的Deff最高为2.134×10⁃9,所需的活化能为16.38 kJ/mol。比较模型预测指标发现,Page模型具有较高的拟合度(R2>0.99),模型预测值和试验值误差仅为2.01%,可较准确地预测AID过程中脱盐海参的水分变化规律。

关键词：脱盐海参气体射流冲击干燥有效水分扩散系数活化能复水

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Guided bone regeneration in long-bone defect with a bilayer mineralized collagen membrane

Collagen and Leather

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Collagen and Leather 2024年第1期5卷 85-100页

作者： Fuli Peng Xuelei Zhang Yilei Wang Rui Zhao Zhiwei Cao Siyu chen Yunxuan Ruan Jingjing Wu tianxi Song Zhiye Qiu Xiao Yang Yi Zeng Xiangdong Zhu Jian Pan Xingdong Zhang Department of Orthopedics West China HospitalOrthopedic Research InstituteSichuan UniversityChengdu 610041SichuanChina National Engineering Research Center for Biomaterials Sichuan UniversityChengdu 610064SichuanChina chengdu Integrated TCM and Western Medicine Hospital Chengdu First People's HospitalChengdu 610041SichuanChina Department of Inspection School of MedicineJiangsu UniversityZhenjiang 212013China State Key Laboratory of Oral Diseases and National Center for Stomatology and National Clinical Research Center for Oral Diseases Department of Oral and Maxillofacial SurgeryWest China Hospital of StomatologySichuan UniversityChengdu 610041SichuanChina State Key Laboratory of New Ceramics and Fine Processing Key Laboratory of Advanced Materials of Min-istry of EducationSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

Bone regeneration for large,critical-sized bone defects remains a clinical challenge *** bone regeneration(GBR)is a promising technique for the repair of multiple bone defects,which is widely used in oral and maxillofacial bone defects but is still unsatisfied in the treatment of long bone ***,we successfully fabricated a bilayer mineralized collagen/collagen(MC/Col)-GBR membrane with excellent osteoinductive and barrier function by coating the MC particles prepared via in situ biomimetic mineralization process on one side of a sheet-like pure collagen *** aim of the present study was to investigate the physicochemical properties and biological functions of the MC/Col film,and to further evaluate its bone regeneration efficiency in large bone defect *** infrared spectra and X-ray diffraction patterns confirmed the presence of both hydroxyapatite and collagen phase in the MC/Col film,as well as the chemical interaction between *** microscope,scanning electron microscopy and atomic force microscope showed the uniform distribution of MC particles in the MC/Col film,resulting in a rougher surface compared to the pure Col *** quantitative analysis of surface contact angle,light transmittance and tensile strength demonstrated that the MC/Col film have better hydrophilicity,mechanical properties,light-barrier properties,*** vitro macrophage co-culture experiments showed that the MC/Col film can effectively inhibit macrophage proliferation and fusion,reducing fibrous capsule *** vivo bone repair assessment of a rabbit critical segmental radial defect proved that the MC/Col film performed better than other groups in promoting bone repair and regeneration due to their unique dual osteoinductive/barrier *** findings provided evidence that MC/Col film has a great clinical potential for effective bone defect repair.

关键词： Mineralized collagen Collagen Guided bone regeneration Artificial periosteum Bone defect repair

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Damage of Flood-causing Rainstorm to Towns in Zhumadian City and Its Countermeasures for Disaster Reduction

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Meteorological and Environmental Research 2015年第11期6卷 16-18,25页

作者： chen Song Wang Jing chen tianxi Zhumadian Meteorological Bureau

Based on meteorological data of Zhumadian City in the past 56 years, the damage of flood-causing rainstorm to towns in Zhumadian City as well as its cataclysm form, influencing system, cataclysm characteristics and action mechanism were analyzed to discuss the characteristics and rules of damage caused by flood-causing rainstorm. Meanwhile, countermeasures against flood-causing rainstorm cataclysm in Zhumadian City were proposed to provide scientific references for early warning and monitoring of flood-causing rainstorm as well as flood control and disaster mitigation.

关键词： Town Flood-causing rainstorm Cataclysm characteristics Influencing system Action mechanism Countermeasures for disaster re- duction

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热拉伸法调控参数对焊接接头残余应力的影响

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船舶工程 2022年第9期44卷 139-146页

作者：陈恬曦陈震陶国君周洪元上海交通大学海洋工程国家重点实验室上海200240 沪东中华造船(集团)有限公司上海200129

为研究热拉伸法调控参数对焊接接头残余应力调控效果的影响,基于热弹塑性有限元法进行中厚板多层多道对接焊的数值仿真。焊接完成后,采用热拉伸法降低焊接残余应力,通过开展系列热拉伸仿真试验,比较分析热拉伸辅助热源宽度、热源距焊缝... 详细信息

为研究热拉伸法调控参数对焊接接头残余应力调控效果的影响,基于热弹塑性有限元法进行中厚板多层多道对接焊的数值仿真。焊接完成后,采用热拉伸法降低焊接残余应力,通过开展系列热拉伸仿真试验,比较分析热拉伸辅助热源宽度、热源距焊缝距离及热源移动速度对高应力区的应力调控作用。结果表明:经热拉伸法处理后,焊缝处压缩塑性应变明显减小,焊接纵向残余拉应力大幅降低;在一定范围内,增加辅助热源宽度或缩短热源距焊缝距离有利于进一步减小焊接纵向残余应力;适当减缓焊后热源移动速度可显著提升应力调控效果,但过小的移动速度不但会改变应力分布趋势,还将导致加热区的纵向残余应力增大;在合理的调控工艺参数下,焊接峰值纵向残余应力降幅可达59.85%。研究结果为焊接接头残余应力的主动应力调控法提供了理论依据。

关键词：多层多道焊焊接残余应力热拉伸法应力调控

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规划院体制改革之我见

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城市规划 2000年第8期24卷 59-61页

作者：陈添喜衡阳市规划设计院

规划院与其他的勘察设计单位有许多不同,政府有部分指令性任务安排,但设计费的到位率一般在20%～50%;挂事业单位的牌子,但绝大多数单位无分毫事业经费,自收自支;主管部门对勘察设计单位提出了明确的改革目标,但规划院的体制改革还在探... 详细信息

规划院与其他的勘察设计单位有许多不同,政府有部分指令性任务安排,但设计费的到位率一般在20%～50%;挂事业单位的牌子,但绝大多数单位无分毫事业经费,自收自支;主管部门对勘察设计单位提出了明确的改革目标,但规划院的体制改革还在探讨和争论之中,旧体制下发生的诸多问题正在我们这貌似强健的躯体内反复冲撞…….各种社会关系的不断变革,危及了我们的生存和发展,怎么力?我认为,当务之急要唱三首歌.

关键词：规划院体制改革城市规划

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