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Depth control of an underwater flight vehicle at low speeds and depths

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Depth control of an underwater flight vehicle at low speeds ...

Application Server Aging Model and Multi-Level Rejuvenation Strategy Using Semi-Markov Process

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作者： Shuo Zhao zhengping Feng tianhai zheng Wanjun Pan School of Naval Architecture Ocean & Civil EngineeringShanghai Jiao Tong University Collaborative Innovation Center for Advanced Ship and Deep Sea Exploration Shanghai Jiao Tong University

Due to low efficiency of control surfaces and considerable wave-suction force, depth control of an underwater fligh vehicle, moving near surface with a low speed, is extremely hard. To improve depth control performance under such challenging scenarios, a depth-oriented driving scheme where independent bow and stern planes are combined to form virtually a singl actuator to generate pure vertical force for heave motion, is proposed. ADRC（active disturbance rejection controller）–base depth controller is then designed. Both the results of simulations and tank tests of depth control of an underwater flight vehicl verify the effectiveness of the driving scheme proposed.

关键词： underwater flight vehicle depth-oriented driving scheme active disturbance rejection controller tank test

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Wuhan University Journal of Natural Sciences 2006年第5期11卷 1209-1215页

作者： ZHAO tianhai QI Yong SHEN Junyi HOU Di zheng Xiaomei LIU Liang School of Electronics and Information Engineering Xi＇an Jiaotong University Xi＇an 710049 Shaanxi China IBM China Research Laboratory Beijing 100094China

Aiming at the characteristic of the dependency between the application components and the application server platform, a rejuvenation strategy with two different levels of rejuvenation granularities is put forward in this paper including the application component reiuvenation and the application server system rejuvenation. The availability and maintenance cost functions are obtained by means of establishing the application server aging model and the boundary condition of the optimal rejuvenation time is analyzed. Theory analysis indicates that the two-level rejuvenation strategy is superior to the traditional single level one. Finally, evaluation experiments are carried out and numerical result shows that compared with the traditional rejuvenation policy, the rejuvenation strategy proposed in this paper can further increase availability of the application server and reduce maintenance cost.

关键词： application server software rejuvenation reliability software maintenance

Comparison of the survival outcomes between primary and secondary muscle-invasive bladder cancer: a propensity score-matched study

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Chinese Medical Journal 2023年第9期136卷 1067-1073页

作者： Waichan Lok Jiapeng Zhang Xiaonan zheng tianhai Lin Hang Xu Ping Tan Qiang Wei Department of Urology Institute of UrologyWest China HospitalSichuan UniversityChengduSichuan 610041China West China Medical School Sichuan UniversityChengduSichuan 610041China Institutes for Systems Genetics Frontiers Science Center for Disease-Related Molecular NetworkWest China HospitalSichuan UniversityChengduSichuan 610041China

Background:Studies have classified muscle-invasive bladder cancer(MIBC)into primary(initially muscle-invasive,PMIBC)and secondary subtypes(initially non-muscle-invasive but progresses,SMIBC),for which controversial survival outcomes were *** study aimed to compare the survival outcomes between PMIBC and SMIBC patients in ***:Patients diagnosed with PMIBC or SMIBC at West China Hospital from January 2009 to June 2019 were retrospectively ***-Wallis and Fisher tests were employed to compare clinicopathological ***-Meier curves and Cox competing proportional risk model were used to compare survival *** score matching(PSM)was employed to reduce the bias and subgroup analysis was used to confirm the ***:A total of 405 MIBC patients were enrolled,including 286 PMIBC and 119 SMIBC,with a mean follow-up of 27.54 and 53.30 months,*** SMIBC group had a higher proportion of older patients(17.65%[21/119]vs.9.09%[26/286]),chronic disease(32.77%[39/119]vs.22.38%[64/286]),and neoadjuvant chemotherapy(19.33%[23/119]vs.8.04%[23/286]).Before matching,SMIBC had a lower risk of overall mortality(OM)(hazard ratios[HR]0.60,95%confidence interval[CI]0.41-0.85,P=0.005)and cancer-specific mortality(CSM)(HR 0.64,95%CI 0.44-0.94,P=0.022)after the initial ***,higher risks of OM(HR 1.47,95%CI 1.02-2.10,P=0.038)and CSM(HR 1.58,95%CI 1.09-2.29,P=0.016)were observed for SMIBC once it became *** PSM,the baseline characteristics of 146 patients(73 for each group)were well matched,and SMIBC was confirmed to have an increased CSM risk(HR 1.83,95%CI 1.09-3.06,P=0.021)than PMIBC after muscle ***:Compared with PMIBC,SMIBC had worse survival outcomes once it became *** attention should be paid to non-muscle-invasive bladder cancer with a high progression risk.

关键词： Mortality Muscle-invasive bladder cancer Propensity score Survival

The Optimal Rejuvenation Schedule Driven by Maintenance Cost in Application Server

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通讯和计算机（中英文版） 2006年第8期3卷 76-81页

作者： tianhai Zhao Yong Qi Junyi Shen Di Hou Xiaomei zheng School of Electronics and Information Engineering Xi＇ an Jiaotong University Xi＇an 710049 China

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基于关联对象组的业务组件请求分配算法

西安交通大学学报 2006年第2期40卷 152-156页

作者：赵天海齐勇沈钧毅郑晓梅西安交通大学电子与信息工程学院西安710049

针对企业Java业务组件(EJB)的负载请求特点,提出了基于关联对象组的EJB负载分配算法(ROGRD).该算法对集群环境下的EJB资源创建情况进行划分,并根据划分的集合在排队论系统模型的基础上建立了代价函数和回报函数,然后依据不同的请求类型... 详细信息

针对企业Java业务组件(EJB)的负载请求特点,提出了基于关联对象组的EJB负载分配算法(ROGRD).该算法对集群环境下的EJB资源创建情况进行划分,并根据划分的集合在排队论系统模型的基础上建立了代价函数和回报函数,然后依据不同的请求类型,且在请求内容的分布,服务器的负载状况以及服务器的处理性能的衰减3个约束条件下,获得代价最小而回报最大分配方案.实验结果表明,ROGRD比基于位置的请求分配算法的响应时间减少了11%,吞吐量提高了28.5%.

关键词：企业Java组件请求分配算法关联对象组

Co‑packaged optics(CPO):status,challenges,and solutions

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Frontiers of Optoelectronics 2023年第1期16卷 1-40页

作者： Min Tan Jiang Xu Siyang Liu Junbo Feng Hua Zhang Chaonan Yao Shixi Chen Hangyu Guo Gengshi Han Zhanhao Wen Bao Chen Yu He Xuqiang zheng Da Ming Yaowen Tu Qiang Fu Nan Qi Dan Li Li Geng Song Wen Fenghe Yang Huimin He Fengman Liu Haiyun Xue Yuhang Wang Ciyuan Qiu Guangcan Mi Yanbo Li tianhai Chang Mingche Lai Luo Zhang Qinfen Hao Mengyuan Qin School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan 430074China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China Department of Electronic and Computer Engineering The Hong Kong University of Science and TechnologyHong KongChina HKUST Fok Ying Tung Research Institute Guangzhou 511462China The Hong Kong University of Science and Technology(Guangzhou) Guangzhou 511462China Chongqing United Micro-Electronics Center(CUMEC) Chongqing 401332China Hisense Broadband Multimedia Technologies Co. Ltd.Qingdao 266000China Institute of Microelectronics Chinese Academy of SciencesBeijing 100029China State Key Laboratory of Superlattices and Microstructures Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China School of Microelectronics Xi’an Jiaotong UniversityXi’an 710049China Zhangjiang Laboratory Shanghai 201210China The State Key Laboratory of Advanced Optical Communication Systems and Networks Department of Electronic EngineeringShanghai Jiao Tong UniversityShanghai 200240China Huawei Technologies Co. Ltd.Shenzhen 440307China College of Computer National University of Defense TechnologyChangsha 410073China Institute of Computing Technology Chinese Academy of SciencesBeijing 100086China

Due to the rise of 5G,IoT,AI,and high-performance computing applications,datacenter trafc has grown at a compound annual growth rate of nearly 30%.Furthermore,nearly three-fourths of the datacenter trafc resides within *** conventional pluggable optics increases at a much slower rate than that of datacenter *** gap between application requirements and the capability of conventional pluggable optics keeps increasing,a trend that is *** optics(CPO)is a disruptive approach to increasing the interconnecting bandwidth density and energy efciency by dramatically shortening the electrical link length through advanced packaging and co-optimization of electronics and *** is widely regarded as a promising solution for future datacenter interconnections,and silicon platform is the most promising platform for large-scale *** international companies(e.g.,Intel,Broadcom and IBM)have heavily investigated in CPO technology,an inter-disciplinary research feld that involves photonic devices,integrated circuits design,packaging,photonic device modeling,electronic-photonic co-simulation,applications,and *** review aims to provide the readers a comprehensive overview of the state-of-the-art progress of CPO in silicon platform,identify the key challenges,and point out the potential solutions,hoping to encourage collaboration between diferent research felds to accelerate the development of CPO technology.

关键词： Co-packaged optics Silicon photonics High-performance computing Advanced packaging External laser Optical power delivery Co-simulation Standardization Transmitter Receiver

Cell softness reveals tumorigenic potential via ITGB8/AKT/glycolysis signaling in a mice model of orthotopic bladder cancer

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Chinese Medical Journal 2024年第2期137卷 209-221页

作者： Shi Qiu Yaqi Qiu Linghui Deng Ling Nie Liming Ge Xiaonan zheng Di Jin Kun Jin Xianghong Zhou Xingyang Su Boyu Cai Jiakun Li Xiang Tu Lina Gong Liangren Liu Zhenhua Liu Yige Bao Jianzhong Ai tianhai Lin Lu Yang Qiang Wei Department of Urology Institute of UrologyNational Clinical Research Center for Geriatrics and Center of Biomedical Big DataWest China Hospital of Sichuan UniversityChengduSichuan 610041China Department of Molecular Oncology Institute of Oncology Research(IOR)Oncology Institute of Southern Switzerland(IOSI)Bellinzona 6500Switzerland Department of Science and Drug Technology University of TurinTurinItaly National Clinical Research Center of Geriatrics The Center of Gerontology and GeriatricsWest China HospitalSichuan UniversityChengduSichuan 610000China Department of Pathology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Pharmaceutics and Bioengineering School of Chemical EngineeringSichuan UniversityChengduSichuan 610000China

Background:Bladder cancer,characterized by a high potential of tumor recurrence,has high lifelong monitoring and treatment *** date,tumor cells with intrinsic softness have been identified to function as cancer stem cells in several cancer ***,the existence of soft tumor cells in bladder tumors remains ***,our study aimed to develop a microbarrier microfluidic chip to efficiently isolate deformable tumor cells from distinct types of bladder cancer ***:The stiffness of bladder cancer cells was determined by atomic force microscopy(AFM).The modified microfluidic chip was utilized to separate soft cells,and the 3D Matrigel culture system was to maintain the softness of tumor *** patterns of integrinβ8(ITGB8),protein kinase B(AKT),and mammalian target of rapamycin(mTOR)were determined by Western *** immunostaining was conducted to examine the interaction between F-actin and tripartite motif containing 59(TRIM59).The stem-cell-like characteristics of soft cells were explored by colony formation assay and in vivo studies upon xenografted tumor ***:Using our newly designed microfluidic approach,we identified a small fraction of soft tumor cells in bladder cancer *** importantly,the existence of soft tumor cells was confirmed in clinical human bladder cancer specimens,in which the number of soft tumor cells was associated with tumor ***,we demonstrated that the biomechanical stimuli arising from 3D Matrigel activated the F-actin/ITGB8/TRIM59/AKT/mTOR/glycolysis pathways to enhance the softness and tumorigenic capacity of tumor ***,we detected a remarkable up-regulation in ITGB8,TRIM59,and phospho-AKT in clinical bladder recurrent tumors compared with their non-recurrent ***:The ITGB8/TRIM59/AKT/mTOR/glycolysis axis plays a crucial role in modulating tumor softness and ***,the soft tumor cells become more sensitive to chemother

关键词： Soft tumor cells 3D Matrigel Stemness Non-muscle invasive bladder neoplasms Microfluidic analytical techniques

中国南瓜海南农家品种资源遗传多样性和亲缘关系研究

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核农学报 2016年第5期30卷 869-877页

作者：郑道君云天海张治礼邓长智谢良商海南省农业科学院热带园艺研究所海南海口571100 海南省农业科学院蔬菜研究所海南海口571100 海南省农业科学院农作物遗传育种莺点实验室海南海口571100

为系统评价中国南瓜海南农家品种资源,通过表型变异结合ISSR和SRAP分子标记技术,对中国南瓜海南农家品种进行遗传多样性和亲缘关系分析。表型分析结果表明,在所有观察的农艺性状中,除蔓性、生长势、果柄、果肉质地等4个性状外,其他性状... 详细信息

为系统评价中国南瓜海南农家品种资源,通过表型变异结合ISSR和SRAP分子标记技术,对中国南瓜海南农家品种进行遗传多样性和亲缘关系分析。表型分析结果表明,在所有观察的农艺性状中,除蔓性、生长势、果柄、果肉质地等4个性状外,其他性状在不同品种间均有不同程度的差异,平均变异系数为34.88%,其中果形的变异最大,部分农艺性状间存在显著的相关性;使用UPGMA法聚类分析可依据叶片大小、叶色和叶尖将28份材料划分为2个类群。ISSR标记和SRAP标记所揭示的遗传多样性水平基本一致,均表明供试品种间存在较大的遗传变异。基于ISSR标记,所有供试品种间的Nei's基因多样性指数H为0.1943,多态性条带百分率PPB为62.90%;基于SRAP标记,H=0.2258,PPB=61.50%;2种标记的UPGMA聚类结果存在显著的相关性,均可将供试品种分为5类,但是其聚类结果与表型分析结果之间相关性较低。综合2种标记的扩增结果,各品种间的平均遗传相似性系数GS值为0.7741,海13和海17亲缘关系最近,而海30与海18遗传基础差异最大。供试中国南瓜海南农家品种间存在较丰富的遗传变异,ISSR和SRAP标记均能有效应用于中国南瓜海南农家品种遗传多样性和亲缘关系研究。研究结果为中国南瓜海南农家品种保护和创新利用提供了科学依据。

关键词：中国南瓜海南农家品种表型变异遗传多样性亲缘关系分子标记

贵州遵义板桥剖面奥陶系湄潭组黑色页岩沉积环境条件判识及烃源意义

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古地理学报 2022年第6期24卷 1193-1209页

作者：黄天海肖笛唐浩李双建郑剑锋周力谭秀成西南石油大学油气藏地质及开发工程国家重点实验室四川成都610500 中国石油集团碳酸盐岩储层重点实验室西南石油大学研究分室四川成都610500 西南石油大学四川省天然气地质重点实验室四川成都610500 中国石化石油勘探开发研究院北京100083 中国石油杭州地质研究院浙江杭州310023

华南上扬子地区下奥陶统湄潭组是一套厚度较大的泥页岩沉积,黑色页岩十分发育,但对其沉积环境的认识争议较大。文中以贵州遵义板桥剖面为例,通过对黑色页岩及其共生岩石的沉积特征及地球化学特征的综合研究,着重分析湄潭组黑色页岩沉积... 详细信息

华南上扬子地区下奥陶统湄潭组是一套厚度较大的泥页岩沉积,黑色页岩十分发育,但对其沉积环境的认识争议较大。文中以贵州遵义板桥剖面为例,通过对黑色页岩及其共生岩石的沉积特征及地球化学特征的综合研究,着重分析湄潭组黑色页岩沉积期的相对水深、沉积水动力条件以及古海水物理化学性质等沉积环境条件。结果表明:(1)板桥剖面湄潭组黑色页岩以颜色暗黑和水平纹理发育良好为显著特征,不产出宏体生物化石,主要以与生屑灰岩或钙质粉砂岩不等厚频繁互层的共生形式产出,说明湄潭组黑色页岩应该不是深水环境的沉积产物,而是在混积台地内低能的浅水泥质潟湖环境中沉积的;(2)与黑色页岩互层的生屑灰岩层段多发育下细上粗的逆粒序结构,顶部可见铁质氧化物,钙质粉砂岩则多发育浪成交错层理和生物钻孔,均呈现出浅水沉积特征;(3)黑色页岩的V/(V+Ni)、Th/U、V/Cr以及Ni/Co的平均值分别为0.71、5.52、1.07和2.04,均指示次氧化—氧化环境;Sr/Ba值介于0.11~2.20之间,平均值为0.55,指示淡水—半咸水环境;(4)生屑灰岩的部分层段可见明显的侵蚀面,镜下可见岩溶发育,同时其REE配分形态趋于水平,∑REE值较高、Y/Ho值较低,具暴露岩溶特征;(5)黑色页岩TOC值介于0.09%~1.05%之间,平均值为0.39%,恢复的原始TOC含量介于0.28%~3.16%之间,平均值为1.25;R平均值为2.095,有机质类型主要为腐泥型。综合上述分析结果,认为遵义板桥剖面湄潭组黑色页岩为一套形成于浅水、次氧化-氧化环境的有效烃源岩,高的古生产力是有机质富集的主要原因。研究结果为判识川南地区湄潭组黑色岩系沉积环境和生烃潜力提供有力的证据,也为浅水成因黑色页岩沉积环境条件判识研究提供了一个新的实例。

关键词：黑色页岩烃源岩浅水沉积环境微量元素稀土元素湄潭组