检索结果-南通市图书馆

Journal of Environmental Sciences 2006年第3期18卷 420-427页

作者： tian yu ZHENG lei SUN De-zhi Department of Environmental Science and Engineering Harbin Institute of Technology Harbin 150090 China.

Extracellular polymeric substances （EPS） are the predominant constituents of activated sludge and represent up to 80% of the mass of activated sludge. They play a crucial role in the flocculation, settling and dewatering of activated sludge. Furthermore, EPS also show great efficiency in binding heavy metals. So EPS are key factors influencing reduction in sludge volume and mass, as well as activity and utilization of sludge. EPS are of considerable environmental interest and hundreds of articles on EPS have been published abroad, while information on EPS in China is limited. In this paper, results of over 60 publications related to constituents and characteristics of EPS and their influences on flocculation, settling and dewatering of sludge are compiled and analyzed. Metal-binding ability of EPS is also discussed, together with a brief consideration of possible research interests in the future.

关键词： activated sludge environmental interest extracellular polymeric substances (EPS)

Regional gray matter abnormality in hepatic myelopathy patients after transjugular intrahepatic portosystemic shunt: a voxel-based morphometry study

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2019年第5期14卷 850-857页

作者： Kang Liu Gang Chen Shu-Yao Ren yuan-Qiang Zhu tian-lei yu Ping tian Chen Li Yi-Bin Xi Zheng-yu Wang Jian-Jun Ye Guo-Hong Han Hong Yin Department of Radiology Xijing Hospital Air Force Military Medical University (Fourth Military Medical University) Department of Radiology Lanzhou General Hospital Lanzhou Military Command Xijing Hospital of Digestive Diseases Air Force Military Medical University (Fourth Military Medical University) Life Sciences Research Center School of Life Sciences and Technology Xidian University

Hepatic myelopathy is a complication seen in patients with chronic liver failure with physiologic or iatrogenic portosystemic shunting. The main symptom is progressive lower limb dyskinesia. The role of the brain motor control center in hepatic myelopathy is unknown. This study aimed to investigate the gray matter changes in patients with hepatic myelopathy secondary to transjugular intrahepatic portosystemic shunt and to examine their clinical relevance. This was a cross-sectional study. Twenty-three liver failure patients with hepatic myelopathy(hepatic myelopathy group), 23 liver failure patients without hepatic myelopathy(non-hepatic myelopathy group) after transjugular intrahepatic portosystemic shunt, and 23 demographically matched healthy volunteers were enrolled from March 2014 to November 2016 at Xijing Hospital, Air Force Military Medical University(Fourth Military Medical University), China. High-resolution magnetization-prepared rapid gradient-echo brain imaging was acquired. Group differences in regional gray matter were assessed using voxel-based morphometry analysis. The relationship between aberrant gray matter and motor characteristics was investigated. Results demonstrated that compared with the non-hepatic myelopathy group, gray matter volume abnormalities were asymmetric, with decreased volume in the left insula(P = 0.003), left thalamus(P = 0.029), left superior frontal gyrus(P = 0.006), and right middle cingulate cortex(P = 0.021), and increased volume in the right caudate nucleus(P = 0.017), corrected with open-source software. The volume of the right caudate nucleus in the hepatic myelopathy group negatively correlated with the lower limb clinical rating of the Fugl-Meyer Assessment(r = –0.53, P = 0.01). Compared with healthy controls, patients with and without hepatic myelopathy exhibited overall increased gray matter volume in both thalami, and decreased gray matter volume in both putamen, as well as in the globus pallidus, cerebellum, and

关键词： portosystemic shunt hepatic myelopathy hepatic encephalopathy magnetic resonance imaging gray matter lower limb Fugl-Meyer Assessment basal ganglia caudate nucleus voxel-based morphometry

Expression of long non-coding RNAs in complete transection spinal cord injury: a transcriptomic analysis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2020年第8期15卷 1560-1567页

作者： Lu Ding Wen-Jin Fu Hong-Yan Di Xiao-Min Zhang yu-tian lei Kang-Zhen Chen Tao Wang Hong-Fu Wu Institute of Stem Cells and Regenerative Medicine Department of PhysiologyGuangdong Medical UniversityDongguanGuangdong ProvinceChina Scientific Research Center the Seventh Affiliated Hospital of Sun Yat-Sen UniversityShenzhenGuangdong ProvinceChina Clinical Laboratory Houjie Hospital of Guangdong Medical UniversityDongguanGuangdong ProvinceChina Department of Neurology Dalingshan HospitalDongguanGuangdong ProvinceChina Department of Hand&Foot Surgery Houjie Hospital of Guangdong Medical UniversityDongguanGuangdong ProvinceChina Department of Surgery the Third Hospital of Guangdong Medical University(Longjiang Hospital of Shunde District)FoshanGuangdong ProvinceChina

Long non-coding RNAs(lncRNAs)are abundantly expressed in the central nervous system and exert a critical role in gene regulation via multiple biological *** uncover the functional significance and molecular mechanisms of lncRNAs in spinal cord injury(SCI),the expression signatures of lncRNAs were profiled using RNA sequencing(RNA-seq)technology in a Sprague-Dawley rat model of the 10th thoracic vertebra complete transection *** showed that 116 of 14,802 detected lncRNAs were differentially expressed,among which 16—including eight up-regulated(H19,Vof16,Hmox2-ps1,LOC100910973,Ybx1-ps3,Nnat,Gcgr,LOC680254)and eight down-regulated(Rmrp,Terc,Ngrn,Ppp2r2b,Cox6a2,Rpl37a-ps1,LOC360231,Rpph1)—demonstrated fold changes>2 in response to transection SCI.A subset of these RNA-seq results was validated by quantitative real-time *** levels of 821 mRNAs were also significantly altered post-SCI;592 mRNAs were up-regulated and 229 mRNAs were down-regulated by more than *** Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analyses showed that differentially expressed mRNAs were related to GO biological processes and molecular functions such as injury and inflammation response,wound repair,and apoptosis,and were significantly enriched in 15 KEGG pathways,including cell phagocytosis,tumor necrosis factor alpha pathway,and leukocyte *** results reveal the expression profiles of lncRNAs and mRNAs in the rat spinal cord of a complete transection model,and these differentially expressed lncRNAs and mRNAs represent potential novel targets for SCI *** suggest that lncRNAs may play an important role in the early immuno-inflammatory response after spinal cord *** study was approved by the Administration Committee of Experimental Animals,Guangdong Province,China.

关键词： cell apotosis complete transection injury high throughput sequencing inflammation ischemia related factor vof-16 long non-coding RNA secondary damage spinal cord TNF signaling transcriptomes

Photocatalytic Characteristics of TiO2/Hangjin 2# Clay Composites

在线全文

学校读者我要写书评

暂无评论

Journal of Chemistry and Chemical Engineering 2010年第2期4卷 7-14页

作者： Huaixiang Li Hao tian lei yu Shanshan Chen College of Chemistry Chemical Engineering and Material Science Shandong Normal University Jinan 250014 China

Composite photocatalyst of TiOg/Hangjin 2# clay has been used as a carrier for the composite photocatalyst due to its low cost prepared by acid-catalyzed sol-gel method. Hangjin 2# clay was and abundant reserves in Inner Mongolia, China. The samples were characterized by X-ray diffraction （XRD）, Fourier transformed infrared spectroscopy （FT-IR）, scanning electron microscopy （SEM） and Brunauer-Emmett-Teller （BET） specific surface area measurements. XRD patterns proved that anatase and rutile phases were coexisted with 52% anatase and 48% ruffle for the TiO2 in the composite. FT-IR analysis demonstrated that the insertion of TiO2 in composite photocatalyst did not destroy the basal framework structure of the clay. SEM results proved the addition of Hangjin 2# clay restrained TiO2 grain growth and the grain size in the composite was smaller than that of pure TiO2 in the same process. Photocatalytic characteristics of TiO2/Hangiin 2~ clay composites were evaluated by measuring degradation ratio of methylene blue （MB） in aqueous solution under ultraviolet （UV） irradiation. Effects of TiO2 wt%, gelling temperature and heat-treating temperature on the photocatalytic activity of the composites were investigated. The composite catalyst showed higher photocatalytic activity than the pure TiO2 under the same experimental conditions. In addition, the composite photocatalysts were easier to recover and reuse than pure TiO2 samples.

关键词： Titanium dioxide clay photocatalysis sol-gel method.

Prediction of Tumor Microenvironment Characteristics and Treatment Response in Lung Squamous Cell Carcinoma by Pseudogene OR7E47P-related Immune Genes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Medical Science 2023年第6期43卷 1133-1150页

作者： Ya-qi ZHAO Hao-han ZHANG Jie WU Lan LI Jing LI Hao ZHONG Yan JIN tian-yu lei Xin-yi ZHAO Bin XU Qi-bin SONG Jie HE Cancer Center Renmin Hospital of Wuhan UniversityWuhan430060China Department of Medical Oncology First Affiliated Hospital of Kunming Medical UniversityKunming650000China National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing100032China

Objective Pseudogenes are initially regarded as nonfunctional genomic sequences,but some pseudogenes regulate tumor initiation and progression by interacting with other genes to modulate their transcriptional *** receptor family 7 subfamily E member 47 pseudogene(OR7E47P)is expressed broadly in lung tissues and has been identified as a positive regulator in the tumor microenvironment(TME)of lung adenocarcinoma(LUAD).This study aimed to elucidate the correlation between OR7E47P and tumor immunity in lung squamous cell carcinoma(LUSC).Methods Clinical and molecular information from The Cancer Genome Atlas(TCGA)LUSC cohort was used to identify OR7E47P-related immune genes(ORIGs)by weighted gene correlation network analysis(WGCNA).Based on the ORIGs,2 OR7E47P clusters were identified using non-negative matrix factorization(NMF)clustering,and the stability of the clustering was tested by an extreme gradient boosting classifier(XGBoost).LASSO-Cox and stepwise regressions were applied to further select prognostic ORIGs and to construct a predictive model(ORPScore)for *** Botling cohorts and 8 immunotherapy cohorts(the Samstein,Braun,Jung,Gide,IMvigor210,Lauss,Van Allen,and Cho cohorts)were included as independent validation *** OR7E47P expression was positively correlated with immune cell infiltration and enrichment of immune-related pathways in LUSC.A total of 57 ORIGs were identified to classify the patients into 2 OR7E47P clusters(Cluster 1 and Cluster 2)with distinct immune,mutation,and stromal *** to Cluster 1,Cluster 2 had more infiltration by immune and stromal cells,lower mutation rates of driver genes,and higher expression of immune-related *** clustering performed well in the internal and 5 external validation *** on the 7 ORIGs(HOPX,STX2,WFS,DUSP22,SLFN13,GGCT,and CCSER2),the ORPScore was constructed to predict the prognosis and the treatment *** addition,the ORPScore was a bette

关键词： pseudogene olfactory receptor family 7 subfamily E member 47 pseudogene-related immune gene tumor microenvironment immunotherapy lung squamous cell carcinoma

Improvement of Photoactivity of Titanium Oxide by Codoping Sn-Li-F Elements

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

材料科学与工程（中英文版） 2010年第6期4卷 44-50页

作者： Huaixiang Li Yingshuai Lv Lusheng Chen Hao tian lei yu Shanshan Chen College of Chemistry Chemical Engineering and Material Science Shandong Normal University Jinan 250014 China

Advancement and Applications of Nanotherapy for Cancer Immune Microenvironment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Medical Science 2023年第4期43卷 631-646页

作者： Jun-ju HE Qing-qing LI Chen ZHAO Jin ZHOU Jie WU Hui-bo ZHANG Ya-qi ZHAO Hao-han ZHANG tian-yu lei Xin-yi ZHAO Zuo YOU Qi-bin SONG Bin XU Cancer Center Renmin Hospital of Wuhan UniversityWuhan 430060China Department of Traditional Chinese Medicine Xianfeng County People's HospitalEnshi 445000China

Cancer treatment has evolved rapidly due to major advances in tumor immunity ***,due to the complexity,heterogeneity,and immunosuppressive microenvir-onment of tumors,the overall efficacy of immunotherapy is only 20%.In recent years,nanoparticles have attracted more attention in the field of cancer immunotherapy because of their remarkable advantages in biocompatibility,precise targeting,and controlled drug ***,the clinical application of nanomedicine also faces many problems concerning biological safety,and the synergistic mechanism of nano-drugs with immunity remains to be *** study summarizes the functional characteristics and regulatory mechanisms of nanoparticles in the cancer immune microenvironment and how nanoparticles activate and long-term stimulate innate immunity and adaptive ***,the current problems and future development trends regarding the application of nanoparticles are fully discussed and prospected to promote the transformation and application of nanomedicine used in cancer treatment.

关键词： nanotherapy tumor microenvironment immunotherapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

不同精料水平对驴利用玉米秸秆日粮的影响

黑龙江畜牧兽医 2009年第9期 40-41页

作者：方雷田磊钰库尔班.麻木提塔里木大学动物科学学院新疆阿拉尔843300 新疆生产建设兵团塔里木畜牧科技重点实验室新疆阿拉尔843300 岳普湖县畜牧局新疆岳普湖844400

20世纪60-70年代,由新疆喀什岳普湖县畜牧局采用关中驴与新疆小毛驴杂交改良后形成了性情温顺、抗病力强、耐干旱炎热气候、生产性能表现较好、遗传性能力稳定的优良后代[1] ,暂称疆岳驴.随着农业生产水平和机械化水平的提高,驴作为交... 详细信息

20世纪60-70年代,由新疆喀什岳普湖县畜牧局采用关中驴与新疆小毛驴杂交改良后形成了性情温顺、抗病力强、耐干旱炎热气候、生产性能表现较好、遗传性能力稳定的优良后代[1] ,暂称疆岳驴.随着农业生产水平和机械化水平的提高,驴作为交通和生产的役用作用已经大大下降,而逐渐转向了肉用和药用价值的开发.但由于长期以来对养驴业的重视不够,相关的科学研究很少,在一定程度上限制了养驴业的发展.试验通过研究在不同精料水平下疆岳驴对玉米秸秆日粮的采食与消化等情况,获得一些基本参数,对驴的饲养管理具有一定的指导意义.

关键词：毛驴玉米秸秆精料水平日粮农业生产水平新疆喀什生产性能机械化水平

Fluorinated poly(p-triphenylene isatin) anion exchange membranes based on hydrophilic hydroxyl side chain modulation for fuel cells

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 702-709页

作者： Yiman Gu Yanchao Zhang Zhanyu Li Yijia lei Baozeng Sun Xiaoyu yu Zhe Wang College of Chemistry and Life Science Changchun University of Technology College of Chemical Engineering Changchun University of Technology School of Materials Science and Engineering Changchun University of Technology Key Laboratory of Advanced Functional Polymer Membrane Materials of Jilin Province

The development of alkaline fuel cells is moving forward at an accelerated pace,and the application of ether-free bonded polymers to anion exchange membranes （AEMs） has been widely ***,the question of the“trade-off”between AEM ionic conductivity and dimensional stability remains *** strategy of inducing microphase separation to improve the performance of AEM has attracted much attention recently,but the design of optimal molecular structures is still being ***,this work introduced different ratios of 3-bromo-1,1,1-trifluoroacetone （x=40,50,and 60） into the main chain of poly（p-terphenylene isatin）.Because fluorinated groups have excellent hydrophobicity,hydrophilic hydroxyl-containing side chains are introduced to jointly adjust the formation of phase separation *** results show that PTI-PTF50-NOH AEM with the appropriate fluorinated group ratio has the best ionic conductivity and alkali stability under the combined effect of *** has an ionic conductivity of 133.83 mS cm-1at 80°*** addition,the OH-conductivity remains at 89%of the initial value at 80°C and 3 M KOH for 1056 h of *** cell polarization curve based on PTI-PTF50-NOH shows a power density of 734.76 mW cm-2at a current density of 1807.7 mA cm-2.

关键词： Anion exchange membranes Poly(p-terphenylene isatin) Hydrophilic-hydrophobic phase separation Fluorinated group

Characterization on Jointed Rock Masses Based on PFC2D

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Characterization on Jointed Rock Masses Based on PFC2D