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Impact of Pulmonary Vein Anatomy on Long-term Outcome of Cryoballoon Ablation for Atrial Fibrillation

Current Medical Science 2018年第2期38卷 259-267页

作者： Shang-wei HUANG Qi JIN Ning ZHANG tian-you ling Wen-qi PAN Chang-jian LIN Qing-zhi LUO Yan-xin HAN Li-qun WU Department of Cardiology Shanghai Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai20025 China

Variant pulmonary vein anatomy （PVA） has been reported to influence the recurrence of atrial fibrillation （AF） after radiofrequency ablation. However, the effects of PVA on AF in patients undergoing cryoballoon ablation （CBA） remain unknown. The present study aimed to examine the impact of PVA on the long-term outcome of CBA for AF. A total of 78 patients （mean age 60.7±10.9 years, 64.1% males） with symptomatic and drug-refractory paroxysmal AF were enrolled in the study. Left atrium （LA） and PVA acquired at computed tomography angiography （CTA） were reconstructed with CARTO 3 SYSTEM. Patients were routinely evaluated by 24-hour Holter monitoring following CBA. Cox regression was used to detect the predictors of AF recurrence after CBA. The results showed abnormal PVA in 30 patients （38.5%） and 18 patients （23.1%） had left common PV （LCPV）. Electrical pulmonary vein isolation was achieved in all patients. After a mean follow-up of 689.5±103.8 days, it was found that patients with abnormal PVA had similar AF recurrence rate to those with normal PVA （26.7% vs. 25.0%, P=0.54）, and there was no significant difference in AF recurrence rate between LCPV patients and non-LCPV patients （33.7% vs. 23.3%, P=0.29）. Cox regression analysis showed that AF duration （72.9±9.0 vs. 42.3±43.2 months, HR 1.001; 95%CI 1.003- 1.014; P〈0.001） and cryo-applications of right-side PVs （3.0±1.6 vs. 4.7±1.7, HR 0.661; 95% CI 0.473-0.925; P=0.016） were independent predictors of freedom from AF, but PVA was not identified as a predictor of long-term success. In conclusion, the variant PVA cannot significantly influence the long-term outcome of AF patients undergoing CBA; longer AF duration and less cryo-applications of right-side PVs are associated with higher AF recurrent rate.

关键词： atrial fibrillation pulmonary vein anatomy cryoballoon ablation

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论强化高校内部审计监督

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煤炭高等教育 2009年第6期27卷 74-75页

作者：田有玲中国矿业大学审计处江苏徐州221116

随着高校管理体制改革的深化,教育审计进入了一个重要的发展机遇期,高校内审工作在学校经济活动中可发挥的作用越来越大。提高高校内部审计工作质量、发挥内部审计成效、扩大内部审计领域等应成为强化高校内部审计监督工作的重要举措。

关键词：高校内部审计独立性监督

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Is right ventricular mid-septal pacing superior to apical pacing in patients with high degree atrio-ventricular block and moderately depressed left ventricular function?

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2014年第6期15卷 507-514页

作者： Kang CHEN Ye MAO Shao-hua LIU Qiong WU Qing-zhi LUO Wen-qi PAN Qi JIN Ning ZHANG tian-you ling Ying CHEN Gang GU Wei-feng SHEN Li-qun WU Department of Cardiology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Outpatient Department Shanghai Jiao Tong University School of Medicine

Objective： We are aimed to investigate whether right ventricular mid-septal pacing （RVMSP） is superior to conventional right ventricular apical pacing （RVAP） in improving clinical functional capacity and left ventricular ejection fraction （LVEF） for patients with high-degree atrio-ventricular block and moderately depressed left ventricle （LV） function. Methods： Ninety-two patients with high-degree atrio-ventricular block and moderately reduced LVEF （ranging from 35% to 50%） were randomly allocated to RVMSP （n=45） and RVAP （n=47）. New York Heart Association （NYHA） functional class, echocardiographic LVEF, and distance during a 6-min walk test （6MWT） were determined at 18 months after pacemaker implantation. Serum levels of N-terminal pro-brain natriuretic peptide （NT-proBNP） were measured using an enzyme-linked immunosorbent assay （ELISA） kit. Results： Compared with baseline, NYHA functional class remained unchanged at 18 months, distance during 6MVVT （485 m vs. 517 m） and LVEF （36.7% vs. 41.8%） were increased, but BNP levels were reduced （2352 pg/ml vs. 710 pg/ml） in the RVMSP group compared with those in the RVAP group, especially in patients with LVEF 35%-40% （for all comparisons, P〈0.05）. However, clinical function capacity and LV function measurements were not significantly changed in patients with RVAP, despite the pacing measurements being similar in both groups, such as R-wave amplitude and capture threshold. Conclusions： RVMSP provides a better clinical utility, compared with RVAP, in patients with high-degree atrioventricular block and moderately depressed LV function whose LVEF levels ranged from 35% to 40%.

关键词： Mid-septal pacing Apical pacing Impaired heart function

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Improved sensing performance of WO_(3) nanoparticles decorated with Ag and Pt nanoparticles

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Rare Metals 2021年第6期40卷 1642-1650页

作者： Dong-Liang Feng Zheng-you Zhu ling-ling Du Xia-Xia Xing Chen Wang Jian Chen Yong-Tao tian Da-Chi Yang tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology and Department of ElectronicsCollege of Electronic Information and Optical EngineeringNankai UniversityTianjin 300350China School of Physics and Engineering and Key Laboratory of Materials Physics Ministry of EducationZhengzhou UniversityZhengzhou 450001China

Gas sensors built with metal oxide semiconductors have attracted tremendous attention due to the growing demand for the detection of inflammable,explosive and toxic ***,to improve the sensing response,WO_(3) nanoparticles decorated with Ag and Pt bimetals(Ag and Pt/WO_(3) NPs)have been developed via combined hydrolysis and hydrothermal *** sensors prototypes show high response to acetone(Ra/Rg=250@100×10^(-6),140℃),which is 6.1 fold as high as that of the pristine WO_(3) NPs(Ra/Rg=41@100×10^(-6),140℃).Moreover,the recovery time of Ag and Pt/WO_(3) NPs was reduced from 138 to 13 s compared with that of the pristine WO_(3) *** improved acetone sensing performance may be attributed to that the chemical and electronic sensitization of Ag and Pt to WO_(3) NPs increases adsorbed oxygen species,speeds up the reaction and thus boosts the sensing *** strategy that decoration of dual precious metals onto WO_(3) NPs improves the acetone sensing performance may be applied to the gas sensors of other sensing materials.

关键词： WO_(3)nanoparticles Ag and Pt bimetals Acetone sensing Chemical sensitization Recovery time

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In-plane current-induced magnetization reversal of Pd/CoZr/MgO magnetic multilayers

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Chinese Physics B 2022年第12期31卷 511-515页

作者： Jing Liu Caiyin you Li Ma Yun Li ling Ma Na tian School of Materials Science and Engineering Xi’an University of TechnologyXi’an 710048China

High critical current density(>10^(6)A/cm^(2))is one of major obstacles to realize practical applications of the currentdriven magnetization reversal *** this work,we successfully prepared Pd/CoZr(3.5 nm)/MgO thin films with large perpendicular magnetic anisotropy and demonstrated a way of reducing the critical current density with a low out-of-plane magnetic field in the Pd/CoZr/MgO *** the assistance of an out-of-plane magnetic field,the magnetization can be fully reversed with a current density of about 10^(4)A/cm^(2).The magnetization reversal is attributed to the combined effect of the out-of-plane magnetic field and the current-induced spin-orbital *** is found that the current-driven magnetization reversal is highly relevant to the temperature owing to the varied spin-orbital torque,and the current-driven magnetization reversal will be more efficient in low-temperature range,while the magnetic field is helpful for the magnetization reversal in high-temperature range.

关键词： critical current density magnetization reversal perpendicular magnetization hybrid driving

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Kinetics of Acicular Ferrite Transformation in Weld Metal

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Journal of Iron and Steel Research International 2001年第1期8卷 34-36页

作者： tian Zhi-ling Cent Iron & Steel Res Inst Beijing 100081 Peoples R China Petr Univ Shandong 257061 Peoples R China tianjin Univ Tianjin 300072 Peoples R China

Acicular Ferrite(AF) is beneficial in welds because it provides a tough and strong ***,much works have been done in the study of the effect of alloying elements and welding conditions aimed at obtaining more AF in the weld ***,the knowledge about the nature of AF is limited due to the lack of kinetics *** this paper,the kinetic curves of AF transformation in an X65 weld metal were established by means of welding thermal simulation *** results showed that AF transformation is a typical diffusion process of nucleation and growth with incubation *** transformation in weld metal obeys the relationship described by JMA *** effect of welding heat input was also studied.

关键词： weld metal acicular ferrite kinetics pipe steel

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Nitrogen Mineralization from Animal Manures and Its Relation to Organic N Fractions

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Journal of Integrative Agriculture 2014年第9期13卷 2040-2048页

作者： LI ling-ling LI Shu-tian Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences International Plant Nutrition Institute (IPNI) Beijing Office

Laboratory aerobic incubation was conducted for 161 d to study N mineralization and the changes of organic N fractions of nine different manures（3 chicken manures, 3 pig manures and 3 cattle manures） from different farms/locations. Results indicated that significant（P〈0.01 or P〈0.001） difference existed in N mineralization between manures. The rapid N mineralization in manures occurred during 56 to 84 d of incubation. First order exponential model can be used to describe N mineralization from chicken manures and pig manures, while quadratic equation can predict mineralization of organic N from cattle manures. An average of 21, 19 and 13% added organic N from chicken manure, pig manure and cattle manure was mineralized during 161 d of incubation. Amino acid-N was the main source of N mineralization. The changes of amino acid-N together with ammonium N could explain significantly 97 and 96% of the variation in mineralized N from manured soils and manures. Amino acid-N and ammonium N are two main N fractions in determining N mineralization potential from manures. Amino acid-N contributed more to the mineralized N than ammonium N.

关键词： N mineralization N fraction pig manure chicken manure cattle manure

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De-novo characterization of the soft-shelled turtle Pelodiscus sinensis transcriptome using Illumina RNA-Seq technology

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第1期14卷 58-67页

作者： Wei WANG Cai-yan LI Chu-tian GE Lei LEI you-ling GAO Guo-ying QIAN Zhejiang Provincial Top Key Discipline of Modern Microbiology and Application College of Biological and Environmental Sciences Zhejiang Wanli University Ningbo 315100 China Henan Provincial Bureau of Animal Husbandry Zhengzhou 450008 China

The soft-shelled turtle Pelodiscus sinensis is a high-profile turtle species because of its nutritional and medicinal value in Asian countries. However, little is known about the genes that are involved in formation of their nutritional quality traits, especially the molecular mechanisms responsible for unsaturated fatty acid and collagen biosynthesis. In the present study, the transcriptomes from six tissues from Pelodiscus sinensis were sequenced using an IIlumina paired-end sequencing platform. We obtained more than 47 million sequencing reads and 73954 unigenes with an average size of 754 bp by de-novo assembly. In total, 55.19% of the unigenes （40 814） had significant similarity with proteins in the National Center of Biotechnology Information （NCBI） non-redundant protein database and Swiss-Prot database （E-value 〈10-5）. Of these annotated unigenes, 9156 and 11 947 unigenes were assigned to 52 gene ontology categories （GO） and 25 clusters of orthologous groups （COG）, respectively. In total, 26496 （35.83%） unigenes were assigned to 242 pathways using the Kyoto Encyclopedia of Genes and Genomes pathway database （KEGG）. In addition, we found a number of highly expressed genes involved in the regulation of P. sinensis unsatu- rated fatty acid biosynthesis and collagen formation, including desaturases, growth factors, transcription factors, and extracellular matrix components. Our data represent the most comprehensive sequence resource available for the Chinese soft-shelled turtle and could provide a basis for new research on this turtle as well as the molecular genetics and functional genomics of other terrapins. To our knowledge, we report for the first time, the large-scale RNA se- quencing （RNA-Seq） of terrapin animals and would enrich the knowledge of turtles for future research.

关键词： Pelodiscus sinensis Illumina RNA-Seq Transcriptome Gene expression

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Annotation and Retrieval System of CAD Models Based on Functional Semantics

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Chinese Journal of Mechanical Engineering 2014年第6期27卷 1112-1124页

作者： WANG Zhansong tian ling DUAN Wenrui State Key Laboratory of Tribology & Institute of Manufacturing Engineering Department of Mechanical EngineeringTsinghua University Beijing Key Lab of Precision/Ultra-precision Manufacturing Equipments and Control Tsinghua University

CAD model retrieval based on functional semantics is more significant than content-based 3D model retrieval during the mechanical conceptual design phase. However, relevant research is still not fully discussed. Therefore, a functional semantic-based CAD model annotation and retrieval method is proposed to support mechanical conceptual design and design reuse, inspire designer creativity through existing CAD models, shorten design cycle, and reduce costs. Firstly, the CAD model functional semantic ontology is constructed to formally represent the functional semantics of CAD models and describe the mechanical conceptual design space comprehensively and consistently. Secondly, an approach to represent CAD models as attributed adjacency graphs（AAG） is proposed. In this method, the geometry and topology data are extracted from STEP models. On the basis of AAG, the functional semantics of CAD models are annotated semi-automatically by matching CAD models that contain the partial features of which functional semantics have been annotated manually, thereby constructing CAD Model Repository that supports model retrieval based on functional semantics. Thirdly, a CAD model retrieval algorithm that supports multi-function extended retrieval is proposed to explore more potential creative design knowledge in the semantic level. Finally, a prototype system, called Functional Semantic-based CAD Model Annotation and Retrieval System（FSMARS）, is implemented. A case demonstrates that FSMARS can successfully botain multiple potential CAD models that conform to the desired function. The proposed research addresses actual needs and presents a new way to acquire CAD models in the mechanical conceptual design phase.

关键词： conceptual design functional semantics attributed adjacency graph CAD Model Repository multi-function extended retrieval

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Extension of π-Calculus with Interval Action Prefixes

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Chinese Journal of Electronics 2016年第5期25卷 848-857页

作者： LUO ling DUAN Zhenhua tian Cong Institute of Computing Theory and Technology Xidian University

This paper presents an extension of π-calculus, named p-π, with interval action prefixes. The syntax and operational semantics of p-π are formalized, and the algebraic and time-dependent properties are *** on them, how time-dependent behaviors of systems can be modeled with p-π is demonstrated. Finally, a case study is given to illustrate how p-π is used in practise.

关键词： π-Calculus Process algebra Interval action prefixes Specification Verification

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