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HIV and intestinal parasite co-infections among a Chinese population: an immunological profile

Infectious Diseases of Poverty 2013年第1期2卷 144-151,143页

作者： Li-Guang tian tian-ping wang Shan Lv Feng-Feng wang Jian Guo Xiao-Mei Yin Yu-Chun Cai Mary Kathryn Dickey Peter Steinmann Jia-Xu Chen National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(China CDC) WHO Collaborating Centre for Malaria Schistosomiasis and FilariasisKey Laboratory of Parasite and Vector BiologyMinistry of HealthShanghai 200025People’s Republic of China Anhui Institute of Parasitic Disease Control Hefei 241000People’s Republic of China University of Oklahoma Midwest 73110OKUSA Department of Epidemiology and Public Health Swiss Tropical and Public Health Institu

Background:Parasite infections often result in a switch of the human body’s predominant immune reaction from T-helper 1(Th1)-type to ***,parasite infections are widely expected to accelerate the progression of human immunodeficiency virus(HIV)infections to acquired immunodeficiency syndrome(AIDS).In the People’s Republic of China,both parasitic diseases and AIDS are epidemic in certain rural areas,and co-infections are relatively ***,no population-based studies have yet investigated the frequency of HIV and parasite co-infections,and its effects on immune *** studied(1)the immune status of an HIV-infected population,and(2)the effect of co-infection of HIV and intestinal parasites on selected parameters of the human immune ***:A total of 309 HIV-infected individuals were recruited and compared to an age-matched and sex-matched control group of 315 local HIV-negative *** were administered to all participants to obtain information on sociodemographic characteristics,sanitation habits,family income,and recent clinical *** consecutive stool samples and 10 ml samples of venous blood were also collected from each individual for the diagnosis of parasite infections and quantitative measurements of selected cytokines and CD4+T-lymphocytes,***:During the study period,79 HIV-infected individuals were not under highly active antiretroviral therapy(HAART)and were thus included in our analysis;the prevalence of intestinal helminth infections was 6.3%and that of protozoa was 22.8%.The most common protozoan infections were Blastocystis hominis(***)(13.9%)and Cryptosporidium spp.(10.1%).The prevalence of Cryptosporidium *** HIV-infected individuals was significantly higher than that in HIV negative individuals(P0.05).However,the following trend

关键词： HIV Intestinalparasite Co-infection Immunological profile People’s Republic of China

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Co-infection of HIV and parasites in China: Results from an epidemiological survey in rural areas of Fuyang city, Anhui province, China

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Frontiers of Medicine 2010年第2期4卷 192-198页

作者： Li-Guang tian tian-ping wang Jia-Xu CHEN Yu-Chun CAI Xiao-Mei YIN Guo-Jin CHENG Wei-Duo WU Peter STEINMANN Jian GUO Xiao-Mei TONG Lan-Hua LI Qin LIU Li ZHOU Feng-Feng wang Zhen-Li wang Xiao-Nong ZHOU National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionWHO Collaborating Center for MalariaSchistosomiasis and FilariasisShanghai 200025China Anhui Institute of Parasitic Disease Control Wuhu 241000China Fuyang Center for Disease Control and Prevention Fuyang 236000China Department of Epidemiology and Public Health Swiss Tropical and Public Health InstituteBasel CH-4000Switzerland University of Basel Basel CH-4000Switzerland Weifang Medical University Weifang 261000China

The aim of this study was to investigate epidemiological characteristics of co-infection of HIV and intestinal parasites in a HIV/AIDS highly endemic area in China.A cross-sectional survey was carried out in two villages where HIV/AIDS prevalence in residents was over 1%.Stool samples of all residents in the two targeted villages were examined for the presence of intestinal *** examination was performed for the HIV infection detection and anemia test.A questionnaire survey was carried out in all residents participating in the study.A total of 769 individuals were enrolled in the investigation,720 of whom were involved in stool examination of intestinal *** infection rates of parasites in the residents of the targeted villages were as follows:0.56%for Ascaris lumbricoides,4.03%for Hookworm,0.28%for Trichuris trichiura,0.42%for Clonorchis sinensis,21.39%for Blastocystis hominis,3.89%for Giardia lamblia,1.67%for Entamoeba spp.,4.44%for Cryptosporidium spp.,and no infection for Strongyloides *** overall infection rate of intestinal worms was 4.72%,intestinal parasite infection rate was 24.31%,the anemia prevalence rate was 34.68%,the co-infection rate of HIV and intestinal helminthes 2.17%,the co-infection rate of HIV and intestinal protozoa 28.26%,of which the co-infection rates of HIV and Blastocystis hominis,and HIV and Cryptosporidium *** 19.57%and 13.04%,respectively.A signiﬁcant difference of Cryptosporidium *** rate was found between HIV-positive group(13.04%)and HIV-negative group(4.70%)(P50%)and women(>39%).It was concluded that the infection rate of intestinal protozoa in the residents was higher than that of intestinal helminthes in the local setting,and a same pattern appeared in the co-infection rate of HIV and *** interestingﬁnding is that the infection rate of Cryptosporidium *** the HIV-positiv

关键词： human immunodeﬁciency virus(HIV) acquired immunodeﬁciency syndrome(AIDS) co-infec-tion intestinal parasites helminthes protozoa China

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Adaptive Perturbation Method for Global Stabilization of Minimally Rigid Formations in the Plane

Adaptive Perturbation Method for Global Stabilization of Min...

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第三十届中国控制会议

作者： tian Yu-ping,wang Qin School of Automation,Southeast University,Nanjing 210096,P.R.China

＜正＞This paper considers the problem of control of a minimally rigid formation shape in a plane for n *** the formation graph contains cycles,undesired equilibria arise under the existing control laws and the global stability of the desired formation is not *** this paper,a constructive adaptive perturbation method is proposed for globally stabilizing minimal rigid *** are added to the movement directions of appropriate n-2 agents in the sub-graph which contains the remaining edges of the minimally rigid formation graph by removing a spanning *** is shown that the proposed novel bidirectional control law can not only guarantee the global asymptotical stability of the desired formation,but also ensure that no collision happens between any two adjacent agents during the *** results are provided to illustrate the effectiveness of the control algorithm.

关键词： Minimally Rigid Graph Multi-Agents System Global Asymptotic Stability

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Structure and function of a novel proteinase A inhibitor (GLPIA1) from by *** by submerged fermentation

Structure and function of a novel proteinase A inhibitor (GL...

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华东六省一市生物化学与分子生物学会2008年学术交流会

作者： tian Ya-ping wang song-hua (The Key Laboratory of Industrial Biotechnology,Ministry of Education,Jiangnan University,Wuxi 214122,P.R.China)

The structure of a novel proteinase A inhibitor(GLPIA)purified from *** by submerged fermentation was researched. There are four kinds monosaccharide in GLPIA determined by gas chromatography, including glucose,mannose,arabinose,rhamnose,the percentage of glucose is about 96%.Analysis by IR Spectrum ,H-NMR and C-NMR,proved that GLPIA is a typical glucoprotein,Its backbone includedβ-1,3-glucide linkage,the branch ofβ-1,6glucosidic linkage exists *** GLPIA was hydrolyzed by neutral proteinase and trypsin or byβ-1,3 glucanase,the inhibitory activity obviously *** explore the relationship between dimensional structure and inhibitor activity of GLPIA,the chemical reaction of Congo red was applied to forecast the dimensional structure of GLPIA and to observe the changes of dimensional structure. The result displays that GLPIA is triple helical conformation in *** being treated with different concentrations of sodium hydroxide,the inhibitor activities vary with the change of dimensional ***,the dimensional structure of GLPIA is tightly related with biological activities.

关键词： Glucidum by submerged fermentation proteinase A inhibitor Congo red structure and function

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Determination of Shionone in Rat Plasma by HPLC and Its Pharmacokinetic study

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Chinese Herbal Medicines 2010年第2期2卷 132-135页

作者： tian Ya-ping,wang Qiao,YANG Wei,KONG De-zhi,ZHANG Lan-tong Department of Pharmaceutical Analysis,School of Pharmacy,Hebei Medical University,Shijiazhuang 050017,China Department of Pharmaceutical Analysis School of PharmacyHebei Medical UniversityShijiazhuang 050017China

Objective To develop a sensitive,simple,and accurate method for the determination of shionone in rat plasma after ig administration of Asteris Radix petroleum ether extract(RAPE).Methods The separation was achieved by HPLC on a RP18 column(150 mm × 3.9 mm,5 μm) with a mobile phase composed of acetonitrile-0.05% phosphoric acid water(98:2) at a flow rate of 1.0 mL/*** Detector was set at 200 nm and friedelin was chosen as an internal *** The linear range of the standard curves was(0.3443-22.0) μg/mL with the correlation coefficient of *** intra-and inter-day precisions were all below 10% and the relative error was -3.5%-1.1%.Conclusion The developed method can be successfully applied to the pharmacokinetic *** ig administration of RAPE,T1/2(ka) is(33.09 ± 7.32) min and T1/2(ke) is(84.95 ± 22.34) min.

关键词： Asteris Radix pharmacokinetic study shionone

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Surveillance-based evidence:elimination of schistosomiasis as a public health problem in the Peoples’Republic of China

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Infectious Diseases of Poverty 2020年第3期9卷 39-50页

作者： Jing Xu Shi-Zhu Li Li-Juan Zhang Robert Bergquist Hui Dang Qiang wang Shan Lv tian-ping wang Dan-Dan Lin Jian-Bing Liu Guang-Hui Ren Kun Yang Yang Liu Yi Dong Shi-Qing Zhang Xiao-Nong Zhou National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionWHO Collaborating Centre for Tropical DiseasesChinese Center for Tropical Disease ResearchShanghai 200025People’s Republic of China Geospatial Health Ingerod 407S-45494 BrastadSweden Anhui Provincial Institute of Schistosomiasis Control HefeiAnhui Province 230061People’s Republic of China Jiangxi Provincial Institute of Parasitic Disease NanchangJiangxi Province 330006People’s Republic of China Hubei Provincial Institute of Schistosomiasis Control Hubei Center for Disease ControlWuhanHubei Province 430079People’s Republic of China Hunan Provincial Institute of Schistosomiasis Control YueyangHunan Province 414000People’s Republic of China Jiangsu Provincial Institute of Schistosomiasis Control WuxiJiangsu Province 214064People’s Republic of China Sichuan Center for Disease Control ChengduSichuan Province 610041People’s Republic of China Yunnan Provincial Institute of Endemic Diseases Control and Prevention DaliYunnan Province 671000People’s Republic of China

Background:A steady progress on schistosomiasis control in the Peoples’Republic of China(***)was achieved and broadened into the twelve-year medium and long term national plan(MLNP)which marled the implementation of an integrated control strategy across all endemic areas in *** in *** understand the endemic trends of schistosomiasis to assess the effectiveness of an integrated strategy,we conducted an analysis of schistosomiasis surveillance data spanned from 2005 to ***:The schistosomiasis sentinel surveillance data from sentinel sites were collected and analyzed from 2005 to *** these sentinel sites,residents aged 6 years or above were screened annually by indirect hemagglutination assay(IHA),while only antibody positives were followed by stool examination either Kato-katz method(KK)and/or hatching technique(HT).Domestic animals raised in sentinel sites were examined by HT for confirming the infection of *** investigation was conducted each year through systematic sampling method combined with environmental sampling *** snails collected from field were tested by microscopic dissection *** infection rates of schistosomes in residents,domestic animals and snails,as well as the indicators reflecting the snails’distribution were calculated and *** analysis was used to examine the changes of the number of eggs per gram feces in population and Chi-square test was used to examine any change in proportions among ***:A total of 148902 residents from sentinel sites attended this study and 631676 blood samples were examined by IHA test during the 11 covered *** annual average antibody positive rates presented a significant decrease trends,from 17.48%(95%CI:17.20–17.75%)in 2005 to 5.93%(95%CI:5.71–6.15%)(χ2=8890.47,P<0.001)in *** 2005–2015,the average infection rate of schistosomes in residents declined from 2.07%(95%CI:1.96–2.17%)to 0.13%(95%CI:0.09–0.16%),accompanied by significant

关键词： Schistosomiasis Surveillance Infection rate Elimination China

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退化抛物方程组整体解存在性

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四川大学学报（自然科学版） 2001年第6期38卷 818-819页

作者：田俐萍王菊西南交通大学峨眉分校四川峨眉614202 成都纺织高等专科学校成都610063

主要考虑一类带有齐次边界条件的退化抛物方程组解的整体存在性。

关键词：退化抛物方程组齐次边界整体存在性边值问题

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凸函数的某些性质及其奇异边值问题的应用

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四川大学学报（自然科学版） 2001年第3期38卷 328-331页

作者：田俐萍王凤琼西南交通大学峨眉分校四川峨眉614202 成都信息工程学院成都610041

讨论了在区间 [a ,b]上凸函数的有界变差性、拟弱收敛性、上确界和一致有界性 ,并应用于一类没有连续性紧性和凹凸性假定下的奇异微分方程的边值问题 .

关键词：凸函数有界变差拟弱收敛上确界与一致有界原理奇界边值问题

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光伏太阳电池研究中的光声技术

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太阳能学报 1982年第2期 196-201页

作者：宋天平王玉江糜天英中国科学院长春应用化学研究所

本文报道了采用光声光谱技术测量某些半导体光电材料的光吸收特性及禁带宽度的结果。样品为高纯CdS、掺杂的CdS和电沉积在Ni片上的CdSe薄膜。用光声功率法测定了CdS-Cu2S固体光伏电池和CdSe∣Na2S-S-NaOH∣Pt电化学光伏电池的光电流谱... 详细信息

本文报道了采用光声光谱技术测量某些半导体光电材料的光吸收特性及禁带宽度的结果。样品为高纯CdS、掺杂的CdS和电沉积在Ni片上的CdSe薄膜。用光声功率法测定了CdS-Cu2S固体光伏电池和CdSe∣Na2S-S-NaOH∣Pt电化学光伏电池的光电流谱和光谱响应。同时也研究了氧化-还原电解液（如Na2S-S-NaOH）的光吸收行为。灾验结果表明,光声光谱技术对于光伏太阳电池的研究是一种很有用的工具。

关键词：光伏电池光谱响应电化学光电流谱太阳电池电解液光声技术

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GLOBALLY ASYMPTOTICALLY STABLE FORMATION CONTROL OF THREE AGENTS

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Journal of Systems Science & Complexity 2012年第6期25卷 1068-1079页

作者： Qin wang Yu-ping tian Yaojin XU School of Automation Southeast University

This paper considers the formatiomshape control of three agents in the plane. By adding an adaptive perturbation to any agent＇s movement direction, a novel control strategy is proposed. It is shown that the proposed novel control law can not only guarantee the global asymptotical stability of the desired formation shape, but also ensure the collision avoidance of agents between each other. Simulation results are provided to illustrate the effectiveness of the control algorithm.

关键词： Formation control global asymptotic stability multi-agents system.

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