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Influence of blood glucose fluctuations on chemotherapy efficacy and safety in type 2 diabetes mellitus patients complicated with lung carcinoma

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World Journal of Diabetes 2024年第4期15卷 645-653页

作者： tian-Zheng Fang Xian-Qiao Wu Ting-Qi Zhao shan-shan Wang Guo-Mei-Zhi Fu Qing-Long Wu Cheng-Wei Zhou Department of Thoracic Surgery The First Affiliated Hospital of Ningbo UniversityNingbo 315020Zhejiang ProvinceChina Department of Endocrine The First Affiliated Hospital of Ningbo UniversityNingbo 315020Zhejiang ProvinceChina Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Ningbo UniversityNingbo 315020Zhejiang ProvinceChina

BACKGROUND Patients with type 2 diabetes mellitus(T2DM)have large fluctuations in blood glucose(BG),abnormal metabolic function and low immunity to varying degrees,which increases the risk of malignant tumor diseases and affects the efficacy of tumor *** hyperglycemia may have important therapeutic implications for cancer *** To clarify the influence of BG fluctuations on chemotherapy efficacy and safety in T2DM patients complicated with lung carcinoma(LC).METHODS The clinical data of 60 T2DM+LC patients who presented to the First Affiliated Hospital of Ningbo University between January 2019 and January 2021 were retrospectively *** patients underwent chemotherapy and were grouped as a control group(CG;normal BG fluctuation with a mean fluctuation<3.9 mmol/L)and an observation group(OG;high BG fluctuation with a mean fluctuation≥3.9 mmol/L)based on their BG fluctuations,with 30 cases *** indices,tumor markers,serum inflammatory cytokines and adverse reactions were comparatively *** correlation analysis was performed to analyze the correlation between BG fluctuations and tumor *** The fasting blood glucose and 2-hour postprandial blood glucose levels in the OG were notably elevated compared with those in the CG,together with markedly higher mean amplitude of glycemic excursions(MAGE),mean of daily differences,largest amplitude of glycemic excursions and standard deviation of blood glucose(P<0.05).In addition,the OG exhibited evidently higher levels of carbohydrate antigen 19-9,carbohydrate antigen 125,carcinoembryonic antigen,neuron-specific enolase,cytokeratin 19,tumor necrosis factor-α,interleukin-6,and highsensitivity C-reactive protein than the CG(P<0.05).Pearson analysis revealed a positive association of MAGE with serum tumor *** incidence of adverse reactions was significantly higher in the OG than in the CG(P<0.05).CONCLUSION The greater the BG fluctuation in LC patients after

关键词： Blood glucose fluctuation Type 2 diabetes mellitus Lung carcinoma Tumor markers

钙钛矿La_(1-x)Sr_xMnO_3纳米晶光催化活性

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中国有色金属学报 2008年第7期18卷 1353-1357页

作者：董抒华田贵山冯柳山东理工大学材料科学与工程学院淄博255049 山东理工大学测试中心淄博255049

采用柠檬酸络合法制备La1-xSrxMnO3(x=0,0.05,0.1,0.3,0.5)纳米光催化剂,应用XRD、UV-vis和SEM等技术表征这些纳米晶的物化性质及微观结构,并研究其对亚甲基蓝紫外光照射降解的光催化活性。结果表明:所得光催化剂为钙钛矿型,均为立方相... 详细信息

采用柠檬酸络合法制备La1-xSrxMnO3(x=0,0.05,0.1,0.3,0.5)纳米光催化剂,应用XRD、UV-vis和SEM等技术表征这些纳米晶的物化性质及微观结构,并研究其对亚甲基蓝紫外光照射降解的光催化活性。结果表明:所得光催化剂为钙钛矿型,均为立方相,原子Sr替代钙钛矿A位La进入晶格中引起晶胞收缩,晶格产生畸变。掺杂Sr后LaMnO3的吸收带边发生明显的红移。Sr最佳掺杂量x=0.1,所形成的La0.9Sr0.1MnO3光催化剂分散性好、尺寸分布较窄,经150 min光照射后光降解率可达67.1%,比LaMnO3作为光催化剂提高32.2%。掺杂Sr后引起的点缺陷-氧空位浓度增加是掺杂Sr后的LaMnO3具有高效光催化活性的主要原因。

关键词：钙钛矿柠檬酸络合 Sr掺杂光催化

Fiber damage of machine-harvested cotton before ginning and after lint cleaning

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Journal of Integrative Agriculture 2018年第5期17卷 1120-1127页

作者： tian Jing-shan ZHANG Xu-yi ZHANG Wang-feng LI Jian-feng YANG Yan-long DONG Heng-yi JIU Xing-li YU Yong-chuan ZHAO Zhan XU Shou-zhen ZUO Wen-qing Key Laboratory of Oasis Eco-Agriculture Xinjiang Production and Construction Corps/College of AgronomyShihezi University Regimental Farm 149 Division EightXinjiang Production and Construction Corps Regimental Farm 133 Division EightXinjiang Production and Construction Corps Regimental Farm 12 Division OneXinjiang Production and Construction Corps

Machine harvesting increases the foreign matter content of seed cotton. Excessive cleaning causes fiber damage and economic loss. Most trading companies in the Xinjiang Uygur Autonomous Region, China have indicated reluctance to use machine-harvested cotton. The first objective was to determine how the fiber quality was affected by the ginning and lint cleaning and how the fiber damage during levels of lint cleaning changed. The second objective was to determine the optimum number of lint cleaners for machine-harvested cotton based on fiber damage. Cotton samples were collected from 13 fields and processed in seven ginneries between 2013 and 2015. The results indicated that ginning and lint cleaning didn＇t have significant effect on fiber strength and significantly affected both fiber length and short fiber index. Fiber length was reduced by more than 1.00 mm from six of 13 fields after lint cleaning, then the damage rate on short fiber index from 11 of 13 fields was more than 20%. The third lint cleaning caused great fiber damage, reducing fiber length by 0.35 mm and increasing short fiber index by 0.65%. So, the lint should be cleaned by one lint cleaner in the Xinjiang, however, the stage of lint cleaning was sometimes omitted when the foreign matter content of lint was little.

关键词： Xinjiang machine-harvested cotton lint cleaning foreign matter

Klebsiella oxytoca EN-B2高效转化羟胺和亚硝态氮的影响因素研究

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贵州大学学报（自然科学版） 2024年第4期41卷 116-124页

作者：邹建国徐兴舟王英田珊王小强王嘉臣陈婵邹婷何腾霞江龙贵州大学生命科学学院贵州贵阳550025 贵州大学山地植物资源保护与种质创新教育部重点实验室贵州贵阳550025

羟胺和亚硝态氮对动植物具有毒害作用,并通过污染环境进一步危害人类健康。本研究以实验室前期分离获得的一株高效转化羟胺和亚硝态氮的克雷伯氏菌(Klebsiella oxytoca)为研究对象,探究不同环境因素对该菌株同时去除羟胺和亚硝态氮的影... 详细信息

羟胺和亚硝态氮对动植物具有毒害作用,并通过污染环境进一步危害人类健康。本研究以实验室前期分离获得的一株高效转化羟胺和亚硝态氮的克雷伯氏菌(Klebsiella oxytoca)为研究对象,探究不同环境因素对该菌株同时去除羟胺和亚硝态氮的影响。结果表明,在碳源为丁二酸钠,接菌量0.4×10^(8) CFU、碳氮比(C/N)15、温度25℃、转速150 r/min和初始pH值8.0条件下,菌株EN-B2对羟胺、亚硝态氮、总氮的去除效率最高,去除率分别达到了99.42%、100.00%和87.76%。此外,本研究通过向亚硝态氮体系中添加不同浓度的羟胺,进一步探讨了羟胺对菌株EN-B2反硝化过程的影响。结果表明,当体系中羟胺浓度超过3 mg/L后,随着羟胺浓度的进一步增加,该菌株在相同时间下亚硝态氮去除速率降低。本研究有助于理解Klebsiella oxytoca EN-B2在羟胺和亚硝态氮混合体系中的除氮特性,为氮污染废水的处理工艺提供重要参考。

关键词： Klebsiella oxytoca 羟胺亚硝态氮环境因素

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多孔碳毡内气相析出诱导的气液两相流动特性研究

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水动力学研究与进展（A辑） 2017年第6期32卷 719-724页

作者：单天祥叶强上海交通大学机械与动力工程学院上海200240

碳毡是一种高孔隙率的纤维堆积多孔材料,被广泛应用于化工、能源等领域。液体流经碳毡时,其中的溶解气会在升温或降压等因素的作用下过饱和析出,从而影响液相的流动。该文以溶解有饱和空气的液态水为工质,利用加热诱导析气的方法实现了... 详细信息

碳毡是一种高孔隙率的纤维堆积多孔材料,被广泛应用于化工、能源等领域。液体流经碳毡时,其中的溶解气会在升温或降压等因素的作用下过饱和析出,从而影响液相的流动。该文以溶解有饱和空气的液态水为工质,利用加热诱导析气的方法实现了对这种特殊气液两相流的可视化观测,并借助测压法和称重法实现了碳毡内流动阻力和空泡份额的定量测量。结果表明:过饱和析出的气泡在碳毡内有明显的滞留效应,导致液相流动阻力与空泡份额的显著增加;流速的提高增强了流体对滞留气泡的冲刷,从而降低了气相含量及其对液相流动的阻碍。

关键词：碳毡气相析出渗透率空泡份额气液两相流动

无线Ad Hoc网络中基于跨层设计的有效用户识别方法

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中国科学院研究生院学报 2009年第5期26卷 681-687页

作者：田珊张灿中国科学院研究生院信息科学与工程学院北京100049 信息安全国家重点实验室(中国科学院研究生院) 北京100049

提出了一种同步DS-CDMA无线Ad Hoc网络中的有效用户识别方法,采用跨层设计,将MAC层SEEDEX协议中的调度信息用于物理层的帧编码和用户识别.接收机首先判断是否存在有效用户,如存在则使用当前时隙所有可能发送数据的节点的扩频码来确定有... 详细信息

提出了一种同步DS-CDMA无线Ad Hoc网络中的有效用户识别方法,采用跨层设计,将MAC层SEEDEX协议中的调度信息用于物理层的帧编码和用户识别.接收机首先判断是否存在有效用户,如存在则使用当前时隙所有可能发送数据的节点的扩频码来确定有效用户,不存在则直接丢弃该数据帧,从而减少了接收机的能量消耗.仿真结果表明,该方法同现存的同类算法比较,减小了运算量,节省了接收机能量,改善了接收机错判概率.

关键词： AdHoc网络 DS-CDMA 有效用户识别跨层 SEEDEX

Ocular surface in patients with different degrees of myopia

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1313-1321页

作者： Yan-Yun Lyu Shuang Wang Xiao-Niao Chen Zhen-Yu Wang shan-shan Huang Yan Yuan Hong-Shuang Lu Wen-Li Yang Li-Ya Qiao Lei tian Ying Jie Tongren Eye Care Center Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Beijing Institute of Ophthalmology Beijing Tongren Eye CenterBeijing Tongren HospitalCapital Medical University and Beijing Ophthalmology and Visual Sciences Key LaboratoryBeijing 100730China Department of Ophthalmology the Third Medical Center of Chinese People’s Liberation Army General HospitalBeijing 100039China Department of Ophthalmology and Visual Science Tokyo Medical and Dental UniversityTokyo 113-8510Japan

AIM:To investigate the clinical features of the ocular surface in patients with different degrees of ***:A cross-sectional study was conducted involving 122 participants with myopia in Beijing Tongren Hospital from February to June,*** completing the Ocular Surface Disease Index(OSDI)score scale,measurements were taken for refraction,biometric parameters and ocular surface *** prevalence,severity and related parameters of the dry eye among different groups based on axial length(AL)were *** analysis was performed between ocular surface parameters and refraction/biometric measurement ***:Statistically significant differences were observed in refractive error,corneal thickness,anterior chamber depth,and subfoveal choroidal thickness among the groups(all P<0.05).With the increase in AL,the incidence and severity of dry eye increased significantly(P<0.05).Moreover,the tear film break-up time(BUT)shortened(P<0.05),and the corneal fluorescein staining(CFS)points increased significantly(P<0.05).OSDI scores were positively correlated with AL and spherical equivalent(SE;both P<0.05);BUT was negatively correlated with AL,SE,and corneal astigmatism(AST;all P<0.05);Schirmer I test(SIT)results were negatively correlated with AL and SE(both P<0.05).CONCLUSION:AL elongation is a risk factor for dry eye onset in myopic *** longer the AL,the more severe the dry eye is,with the increased CFS spots and tear film ***,SE and AST exhibit negative correlations with dry eye symptom scores and ocular surface parameters.

关键词： myopia axial length ocular surface dry eye

普遍语法与语言范式——从哲学、心理学到生物学的历程

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自然辩证法研究 2007年第2期23卷 18-22页

作者：代天善武汉大学哲学学院湖北武汉430072

普遍语法思想具有悠久的认识论渊源。乔姆斯基认为普遍语法是人脑初始状态与生俱来的生物属性,语言研究最终会同主流的自然科学统一融合。本文扼要论述了普遍语法从哲学、心理学到生物遗传与进化三个主要的发展阶段。作者指出普遍语法... 详细信息

普遍语法思想具有悠久的认识论渊源。乔姆斯基认为普遍语法是人脑初始状态与生俱来的生物属性,语言研究最终会同主流的自然科学统一融合。本文扼要论述了普遍语法从哲学、心理学到生物遗传与进化三个主要的发展阶段。作者指出普遍语法不仅改变了传统语言研究的范式,其自身也经历了多个范式的转变,当前提出的“唯递归性假设”就是普遍语法在生物遗传与进化研究基础之上的最新进展。

关键词：普遍语法最筒方案语言进化语言范式

The Research on Production System Conformation Decision-making based on the Environmental Protection

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The Research on Production System Conformation Decision-maki...