检索结果-南通市图书馆

同方期刊数据库

A Hybrid Approach for Predicting the Remaining Useful Life of Bearings Based on the RReliefF Algorithm and Extreme Learning machine

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第8期140卷 1405-1427页

作者： Sen-Hui Wang Xi Kang Cheng Wang tian-Bing ma Xiang He Ke Yang School of Mechatronics Engineering Anhui University of Science and TechnologyHuainan232001China Institute of Energy Hefei Comprehensive National Science CenterHefei230031China

Accurately predicting the remaining useful life(RUL)of bearings in mining rotating equipment is vital for mining *** research aims to distinguish the features associated with the RUL of bearings and propose a prediction model based on these selected *** study proposes a hybrid predictive model to assess the RUL of rolling element *** proposed model begins with the pre-processing of bearing vibration signals to reconstruct sixty time-domain *** hybrid model selects relevant features from the sixty time-domain features of the vibration signal by adopting the RReliefF feature selection ***,the extreme learning machine(ELM)approach is applied to develop a predictive model of RUL based on the optimal *** model is trained by optimizing its parameters via the grid search *** training datasets are adjusted to make them most suitable for the regression model using the cross-validation *** proposed hybrid model is analyzed and validated using the vibration data taken from the public XJTU-SY rolling element-bearing *** comparison is constructed with other traditional *** experimental test results demonstrated that the proposed approach can predict the RUL of bearings with a reliable degree of accuracy.

关键词： Bearing degradation remaining useful life estimation RReliefF feature selection extreme learning machine

High-entropy oxide-supported platinum nanoparticles for efficient hydrogen evolution reaction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第4期43卷 1537-1546页

作者： Ming-Yu Fan Jia-Jun Wang Jun Zhao Hong Zhang tian-Yi ma Xiao-Peng Han Wen-Bin Hu School of materials Science and Engineering Tianjin Key Laboratory of Composite and Functional Materials Key Laboratory of Advanced Ceramics and Machining TechnologyTianjin UniversityTianjin300350China Joint School of National University of Singapore and tianjin University International Campus of Tianjin UniversityFuzhou350207China School of Science RMIT UniversityMelbourneVIC3000Australia

High-entropy oxides(HEOs)are a new class of single-phase structures with unique electronic and catalytic properties;therefore,it is worthwhile to explore their applications in *** this study,a Pt/(FeCoNiCrAl)_(3)O_(4)nanohybrid using HEO as a support was developed as an efficient catalyst for the hydrogen evolution reaction(HER).Pt/(FeCoNiCrAl)_(3)O_(4)exhibited high HER activity with a low overpotential of 22 mV at10 ma·cm^(-2),outperforming other binary,ternary,and quaternary *** HER activity of Pt/(FeCoNiCrAl)_(3)O_(4)was higher than that of a commercial Pt/C with a significantly lower Pt *** catalyst exhibited good activity and long-term stability(60 h)in an electrolytic water-splitting *** good activity can be attributed to the fact that the introduction of Pt effectively facilitates electronic interactions between Pt and the *** addition,the HEO substrate was more favorable for dispersing Pt particles,optimizing the electrochemical specific surface area,and significantly reducing the charge resistance of the *** study extends the application of HEOs in electrocatalysis and demonstrates the promising prospects of HEOs as supports for electrocatalysts.

关键词： High-entropy oxides Hydrogen evolution reaction Nanohybrid Water electrolysis

SIRT1 inhibits apoptosis of human lens epithelial cells through suppressing endoplasmic reticulum stress in vitro and in vivo

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第7期17卷 1205-1216页

作者： Hui Cui Di Sun Sheng Meng tian-Ju ma Zi Ye Zhao-Hui Li Medical School of Chinese PLA Beijing 100089China Senior Department of Ophthalmology the Third Medical Center of PLA General HospitalBeijing 100853China

AIM:To explore the effect of silent information regulator factor 2-related enzyme 1(SIRT1)on modulating apoptosis of human lens epithelial cells(HLECs)and alleviating lens opacification of rats through suppressing endoplasmic reticulum(ER)***:HLECs(SRA01/04)were treated with varying concentrations of tunicamycin(TM)for 24h,and the expression of SIRT1 and C/EBP homologous protein(CHOP)was assessed using real-time quantitative polymerase chain reaction(RT-PCR),Western blotting,and *** morphology and proliferation was evaluated using an inverted microscope and cell counting kit-8(CCK-8)assay,*** the SRA01/04 cell apoptosis model,which underwent siRNA transfection for SIRT1 knockdown and SRT1720 treatment for its activation,the expression levels of SIRT1,CHOP,glucose regulated protein 78(GRP78),and activating transcription factor 4(ATF4)were *** potential reversal of SIRT1 knockdown effects by 4-phenyl butyric acid(4-PBA;an ER stress inhibitor)was *** vivo,age-related cataract(ARC)rat models were induced by sodium selenite injection,and the protective role of SIRT1,activated by SRT1720 intraperitoneal injections,was evaluated through morphology observation,hematoxylin and eosin(H&E)staining,Western blotting,and ***:SIRT1 expression was downregulated in TMinduced SRA01/04 ***,in SRA01/04 cells,both cell apoptosis and CHOP expression increased with the rising doses of *** stress was stimulated by TM,as evidenced by the increased GRP78 and ATF4 in the SRA01/04 cell apoptosis *** of SIRT1 by siRNA knockdown increased ER stress activation,whereas SRT1720 treatment had opposite results.4-PBA partly reverse the adverse effect of SIRT1 knockdown on *** vivo,SRT1720 attenuated the lens opacification and weakened the ER stress activation in ARC rat ***:SIRT1 plays a protective role against TM-induced apoptosis in HLECs and slows the progression of cataract in

关键词： silent information regulator factor 2-related enzyme 1 endoplasmic reticulum stress apoptosis human lens epithelial cells cataract

Microenvironment-responsive nanosystems for osteoarthritis therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineered Regeneration 2024年第1期5卷 92-110页

作者： Song Li Yuan Xiong Hao Zhu tian ma Xuying Sun Jun Xiao Department of Orthopaedic Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Chemical Engineering and Biotechnology Nanyang Technological University21 Nanyang LinkSingapore 637371Republic of Singapore

Osteoarthritis(OA)represents an enduring and widespread global burden,causing significant morbidity and disability,whose pathology is characterized by persistent inflammation,progressive cartilage degeneration,ab-normal bone homeostasis,and excessive synovial hyperplasia,resulting from its complex ***,current therapeutic approaches for OA remain suboptimal,prompting increased interest in ad-vanced nanotechnology as a means to enhance therapeutic *** recent years,significant progress has been made in the development of versatile nanoplatforms designed to the specific microenvironment of OA,resulting in promising results and introducing the concept of“OA nanomedicine”.Compared to the conventional therapies like non-steroidal anti-inflammatory drugs(NSAIDs),OA nanomedicine offers precise targeted,controllable and personalized ways for OA therapy,contributing to better ***,a comprehensive review consoli-dating the“OA nanomedicine”is currently absent from ***,in this review,we aim to unravel the key pathological and microenvironmental characteristics of OA while summarizing the properties and advantages of nanosystems possessing microenvironment-reprogramming capabilities for OA ***,we make a retro-spection of the features of OA pathology and OA ***,we provide an overview of the advances in OA ***,we discuss the present challenges associated with OA nanomedicine and provide insights into its future prospects from a clinical-translational *** doing so,this review can foster and propel the successful development of OA nanomedicine,addressing the unmet needs in OA therapy.

关键词： Osteoarthritis Nanomedicine Therapy Microenvironment Cartilage Tissue regeneration

Development and evaluation of a quadruple real-time fluorescence-based quantitative reverse transcription polymerase chain reaction assay for detecting Langya, Mojiang, Nipah, and Cedar viruses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biosafety and Health 2024年第2期6卷 80-87页

作者： Wenjun He tian ma Yalan Wang Weifang Han Jun Liu Wenwen Lei Le Zhang Guizhen Wu School of Public Health and management Shandong First Medical University&Shandong Academy of Medical SciencesJinan 250117China NHC Key Laboratory of Biosafety National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China

The emerging viruses within the genus Henipavirus in the family Paramyxoviridae pose a great threat to public *** develop a quadruple real-time fluorescence-based quantitative reverse transcription polymerase chain reaction(qRT-PCR)assay is pivotal for the early warning of the potential of zoonotic infectious *** primers and probes were designed for the relatively conserved regions based on whole genome sequences of Langya virus(LayV),Mojiang virus(MojV),Nipah virus(NiV),and Cedar virus(CedV),followed by the establishment of a quadruple real-time fluorescence-based qRT-PCR detection *** cross-reactivity was observed with other viral nucleic *** optimal linear detection range for LayV,MojV,NiV,and CedV was 10^(1)-10^(8)copies/μL,and the lower limit of detection was 10 copies/μ*** different DNA concentrations of LayV,MojV,NiV,and CedV(10^(4),10^(5),and 10^(6)copies/μL)were tested 14 times,achieving good *** standard deviation of the cycle threshold values for each concentration was90%,and the correlation coefficient was>*** established quadru-ple real-time fluorescence-based qRT-PCR assay for the detection of LayV,MojV,NiV,and CedV exhibits good sensitivity,specificity,and ***,it can be used to detect Henipavirus and other related clinical specimens.

关键词： Real-time fluorescence-basedq RT-PCR Langyavirus Mojiang virus Nipahvirus Cedar virus

Tungsten oxide-anchored Ru clusters with electron-rich and anti-corrosive microenvironments for efficient and robust seawater splitting

在线全文

学校读者我要写书评

暂无评论

Susmat 2024年第1期4卷 106-115页

作者： Yiming Zhang Weiqiong Zheng Huijuan Wu Ran Zhu Yinghan Wang mao Wang tian ma Chong Cheng Zhiyuan Zeng Shuang Li College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengduChina Department of Chemical and Biomolecular Engineering National University of SingaporeSingaporeSingapore Department of materials Science and Engineering and State Key Laboratory of Marine PollutionCity University of Hong KongKowloonHong KongChina Shenzhen Research Institute City University of Hong KongShenzhenChina

Ruthenium(Ru)has been recognized as a prospective candidate to substitute platinum catalysts in water-splitting-based hydrogen ***,minimizing the Ru contents,optimizing the water dissociation energy of Ru sites,and enhancing the long-term stability are extremely required,but still face a great ***,we report on creating tungsten oxide-anchored Ru clusters(Ru-WO_(x))with electron-rich and anti-corrosive microenvironments for efficient and robust seawater *** from the abundant oxygen vacancy structure in tungsten oxide support,the Ru-WO_(x)exhibits strong Ru-O and Ru-W bonds at the *** study elucidates that the strong Ru-O bonds in Ru-WO_(x)may accelerate the water dissociation kinetics,and the Ru-W bonds will lead to the strong metal-support interaction and electrons transfer fromWto *** optimal Ru-WO_(x)catalysts exhibit a low overpotential of 29 and 218mVat the current density of 10 ma cm^(−2) in alkaline and seawater media,*** outstanding long-term stability discloses that the Ru-WO_(x)catalysts own efficient corrosion resistance in seawater *** believe that thiswork offers new insights into the essential roles of electron-rich and anti-corrosivemicroenvironments in Ru-based catalysts and provide a new pathway to design efficient and robust cathodes for seawater splitting.

关键词： hydrogen production microenvironment modulation noble metal catalysts seawater splitting tungsten oxide

Effect of VOJTA Therapy on Gross Motor Function in Children with Cerebral Palsy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Pediatrics 2024年第2期14卷 359-363页

作者： tian ma Ceng Li Yabo Liu Rehabilitation Department of Jingzhou First People’s Hospital Jingzhou China Jingzhou Hospital of Traditional Chinese Medicine Jingzhou China Changjiang Art Engineering Vocational and Technical College Jingzhou China

Objective: To investigate the effect of VOJTA therapy on gross motor function in children with cerebral palsy. Methods: The 86 children with cerebral palsy were all from the First People’s Hospital of Jingzhou City from January 2023-December 2023, and were divided into the control group and the study group with 43 cases according to the principle of voluntariness. Results: In terms of total effective rate of treatment, the gross motor function scale-88 (GMFM-88) was used to evaluate the effective rate before and after treatment, and the effective rate of the study group was higher than that of the control group, and the difference was statistically significant, and the scores of gross motor items of GMFM-88 were better than those of the control group after treatment, and the difference was statistically significant (P 0.05). Conclusion: The application of VOJTA therapy in the treatment of children with cerebral palsy can not only promote the rehabilitation of gross motor function, but also help to improve the treatment effect, and the earlier the treatment, the better.

关键词： VOJTA Therapy Children with Cerebral Palsy Gross Motor Function

Treatment of nasopharyngeal carcinoma and prevention of nonalcoholic Wernicke’s disease:A case report and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第24期12卷 5628-5635页

作者： Yu-Yang ma Xiao-Chan He Yu Gao tian-tian ma Gong Cheng Chang-Wu Yue Yan’an Key Laboratory of Microbial Drug Innovation and Transformation School of Basic MedicineYan’an UniversityYan’an 716000Shaanxi ProvinceChina Department of Cardiology Second DivisionShaanxi Provincial People’s HospitalXi’an 710000Shaanxi ProvinceChina Xi’an Honghui Hospital Xi’an Jiaotong UniversityXi’an 710000Shaanxi ProvinceChina

BACKGROUND Wernicke encephalopathy is a neurological disorder caused by thiamine deficiency,commonly seen in alcoholic populations but also involving other circumstances that may lead to thiamine *** recognition of Wernicke encephalopathy often depends on clinicians’keen ability to detect its typical triad of features;however,most cases do not present with the full constellation of signs,which complicates the timely identification of Wernicke *** SUMmaRY This case report describes a patient with nasopharyngeal carcinoma who developed abnormal ocular function and ataxia following concurrent chemoradiotherapy,without a history of alcohol *** the aid of radiological examinations,he received a timely diagnosis and treatment;however,his symptoms did not fully resolve during *** For patients with malignant tumors exhibiting neurological symptoms,clinicians should consider the possibility of Wernicke encephalopathy and provide prophylactic thiamine therapy.

关键词： Nasopharyngeal carcinoma Non-alcoholic Wernicke’s disease Wernicke’s encephalopathy Neurological Case report

Fine mapping and characterization of a major QTL for grain length,***-2D.1,that has pleiotropic effects in synthetic allohexaploid wheat

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第9期23卷 2911-2922页

作者： Mingming Wang Jia Geng Zhe Zhang Zihan Zhang Lingfeng Miao tian ma Jiewen Xing Baoyun Li Qixin Sun Yufeng Zhang Zhongfu Ni Frontiers Science Center for Molecular Design Breeding/Key Laboratory of Crop Heterosis and Utilization Ministry of Education/Beijing Key Laboratory of Crop Genetic ImprovementChina Agricultural UniversityBeijing 100193China National Plant Gene Research Centre Beijing 100193China

Grain size is one of the determinants of grain yield,and identifying the genetic loci that control grain size will be helpful for increasing grain *** our previous study,a quantitative trait locus(QTL)for grain length(GL),***-2D.1,was identified from an F2 population developed from the cross between the natural(TAA10)and synthetic(XX329)allohexaploid *** the present study,we mainly fine mapped and validated its genetic *** this end,multiple near-isogenic lines(NILs)were obtained through marker-assisted selection with TAA10 as the recurrent *** secondary populations derived from 25 heterozygous recombinants were used for fine mapping of ***-2D.1,and the allele from XX329 significantly increased GL,thousand-grain weight(TGW),total spikelet number per spike(TSN)and spike compactness(SC).Using NILs for XX329(2D+)and TAA10(2D−),we determined the genetic and pleiotropic effects of *** target sequences were aligned with the wheat reference genome RefSeq v2.1 and spanned an~0.9 Mb genomic ***2D03G0114900(ortholog of Os03g0594700)was predicted as the candidate gene based on whole-genome re-sequencing and expression *** summary,the map-based cloning of ***-2D.1 will be useful for improving grain weight with enhanced GL and TSN.

关键词： grain length total spikelet number per spike spike compactness near-isogenic lines QTL wheat