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极限强度状态下钢—混凝土组合梁的有效宽度

钢结构(中英文) 2008年第12期 91-91页

作者： Jian-Guo Nie , chun-Yu tian and c.s. cai

在钢-混凝土组合梁截面中,部分混凝土板作为梁的翼缘以抵抗纵向压力。由于剪力滞后效应引起贯通板厚的非均匀应力分布,在实际设计中通常提出有效宽度的概念以避免对这种现象进行直接分析评估。在现有的研究中,很多研究者采用了相同的有... 详细信息

在钢-混凝土组合梁截面中,部分混凝土板作为梁的翼缘以抵抗纵向压力。由于剪力滞后效应引起贯通板厚的非均匀应力分布,在实际设计中通常提出有效宽度的概念以避免对这种现象进行直接分析评估。在现有的研究中,很多研究者采用了相同的有效宽度定义,在正弯矩情况下,有可能得到组合梁不精确的抗弯能力。本文提出了正弯矩情况下,组合梁极限分析中有效宽度的新定义。通过试验和有限元模型检验了混凝土板的纵向应变和应力并用简化公式进行表达。基于这些简化公式和所采用的一些假定,得到了极限强度状态下混凝土板的有效宽度以及正弯矩下变参数组合梁受压区的高度。研究发现:极限强度下的有效宽度比正常使用状态下的要大。对于极限强度设计,提出了相应简化设计公式。

关键词：钢-混凝土组合有效宽度极限强度状态试验有限元

Research status and prospec.s.of the fractal analysis of metal material surfac.s.and interfaces

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 20-38页

作者： Qinjin Dai Xuefeng Liu Xin Ma shaojie tian Qinghe cui Beijing Advanced Innovation center for Materials Genome Engineering University of Science and Technology BeijingBeijing 100083China Beijing Laboratory of Metallic Materials and Proc.s.ing for Modern Transportation University of Science and Technology BeijingBeijing 100083China Laboratory for Advanced Materials Proc.s.ing of Ministry of Education University of Science and Technology BeijingBeijing 100083China school of Mechanical and Electrical Engineering Xinjiang Institute of EngineeringUrumqi 830023China

As a mathematical analysis method,fractal analysis can be used to quantitatively describe irregular shapes with self-similar or self-affine *** analysis has been used to characterize the shapes of metal materials at various scales and *** methods make it difficult to quantitatively describe the relationship between the regular characteristics and properties of metal material surfac.s.and ***,fractal analysis can be used to quantitatively describe the shape characteristics of metal materials and to establish the quantitative relationships between the shape characteristics and various properties of metal *** the perspective of two-dimensional planes and three-dimensional curved surfac.s.this paper reviews the current research status of the fractal analysis of metal precipitate interfac.s.metal grain boundary interfac.s.metal-deposited film surfac.s.metal fracture surfac.s.metal machined surfac.s.and metal wear *** relationship between the fractal dimensions and properties of metal material surfac.s.and interfac.s.is *** from three perspectives of fractal analysis,namely,research scope,image acquisition methods,and calculation methods,this paper identifies the direction of research on fractal analysis of metal material surfac.s.and interfac.s.that need to be *** is believed that revealing the deep influence mechanism between the fractal dimensions and properties of metal material surfac.s.and interfac.s.will be the key research direction of the fractal analysis of metal materials in the future.

关键词： metal material surfac.s.and interfaces fractal analysis fractal dimension homogeneity

Nanocarrier-mediated siRNA delivery:a new approach for the treatment of traumatic brain injury-related Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2538-2555页

作者： Jie Jin Huajing Zhang Qianying Lu Linqiang tian sanqiao Yao Feng Lai Yangfan Liang chuanchuan Liu Yujia Lu sijia tian Yanmei Zhao Wenjie Ren Institute of Disaster and Emergency Medicine Tianjin UniversityTianjinChina Key Laboratory for Disaster Medicine Technology TianjinChina Henan Medical Key Laboratory for Research of Trauma and Orthopedics The Third Affiliated Hospital of Xinxiang Medical UniversityXinxiangHenan ProvinceChina clinical Medical center of Tissue Engineering and Regeneration Xinxiang Medical UniversityXinxiangHenan ProvinceChina Institutes of Health central Plain Xinxiang Medical UniversityXinxiangHenan ProvinceChina school of Public Health Xinxiang Medical UniversityXinxiangHenan ProvinceChina

Traumatic brain injury and Alzheimer's disease share pathological similarities,including neuronal loss,amyloid-βdeposition,tau hyperphosphorylation,blood-brain barrier dysfunction,neuroinflammation,and cognitive ***,traumatic brain injury can exacerbate Alzheimer's disease-like pathologies,potentially leading to the development of Alzheimer's *** offer a potential solution by facilitating the delive ry of small interfering RNAs across the blood-brain barrier for the targeted silencing of key pathological genes implicated in traumatic brain injury and Alzheimer's disease.U nlike traditional approaches to neuro regeneration,this is a molecula r-targeted strategy,thus avoiding non-specific drug *** review foc.s.s on the use of nanocarrier systems for the efficient and prec.s. delive ry of siRNAs,disc.s.ing the advantages,challenges,and future *** principle,siRNAs have the potential to target all genes and non-targetable protein s,holding significant promise for treating various *** the various therapeutic approaches currently available for neurological diseases,siRNA gene silencing can prec.s.ly"turn off"the expression of any gene at the genetic level,thus radically inhibiting disease progression;however,a significant challenge lies in delivering siRNAs across the blood-brain *** have received increasing attention as an innovative drug delive ry tool fo r the treatment of brain *** are considered a potential therapeutic.s.rategy with the advantages of being able to cross the blood-brain barrier,targeted drug delivery,enhanced drug stability,and multifunctional *** use of nanoparticles to deliver specific modified siRNAs to the injured brain is gradually being recognized as a feasible and effective *** this strategy is still in the preclinical exploration stage,it is expected to achieve clinical translation in the future,creating a new field of molecular tar

关键词： blood-brain barrier cognitive dysfunction exosomes gene silencing immunotherapy inorganic nanomaterials liposome nanoparticles neuroinflammation polymer nanoparticles stem cells

A Novel self-supervised Learning Network for Binocular Disparity Estimation

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computer Modeling in Engineering & sciences 2025年第1期142卷 209-229页

作者： Jiawei tian Yu Zhou Xiaobing chen salman A.AlQahtani Hongrong chen Bo Yang siyu Lu Wenfeng Zheng Department of computer science and Engineering Major in Bio Artificial IntelligenceHanyang UniversityAnsan-si15577Republic of Korea school of Electrical and computer Engineering Louisiana State UniversityBaton RougeLA 70803USA Department of computer Engineering College of Computer and Information SciencesKing Saud UniversityRiyadh11574Saudi Arabia school of Automation University of Electronic Science and Technology of ChinaChengdu610054China

Two-dimensional endoscopic images are susceptible to interferenc.s.such as specular reflections and monotonous texture illumination,hindering accurate three-dimensional lesion reconstruction by surgical *** study proposes a novel end-to-end disparity estimation model to address these *** approach combines a Pseudo-siamese neural network architecture with pyramid dilated convolutions,integrating multi-scale image information to enhance robustness against lighting *** study introduc.s.a Pseudo-siamese structure-based disparity regression model that simplifies left-right image comparison,improving accuracy and *** model was evaluated using a dataset of stereo endoscopic videos captured by the Da Vinci surgical robot,comprising simulated silicone heart sequenc.s.and real heart video *** results demonstrate significant improvement in the network’s resistance to lighting interference without substantially increasing ***,the model exhibited faster convergence during training,contributing to overall performance *** study advanc.s.endoscopic image proc.s.ing accuracy and has potential implications for surgical robot applications in complex environments.

关键词： Parallax estimation parallax regression model self-supervised learning Pseudo-siamese neural network pyramid dilated convolution binocular disparity estimation

Ultra‑High sensitivity Anisotropic Piezoelectric.s.nsors for structural Health Monitoring and Robotic Perception

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Nano-Micro Letters 2025年第2期17卷 432-446页

作者： Hao Yin Yanting Li Zhiying tian Qichao Li chenhui Jiang Enfu Liang Yiping Guo state Key Laboratory of Metal Matrix composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China Beijing Vacuum Electronics Research Institute Beijing 100015People’s Republic of China Fundamental science On Vibration Shock and Noise LaboratoryState Key Laboratory of Mechanical System and VibrationSchool of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Monitoring minuscule mechanical signals,both in magnitude and direction,is imperative in many application scenarios,e.g.,structural health monitoring and robotic.s.nsing ***,the piezoelectric.s.nsor struggles to satisfy the requirements for directional recognition due to the limited piezoelectric coefficient matrix,and achieving sensitivity for detecting micrometer-scale deformations is also ***,we develop a vector sensor composed of lead zirconate titanate-electronic grade glass fiber composite filaments with oriented arrangement,capable of detecting minute anisotropic *** as-prepared vector sensor can identify the deformation directions even when subjected to an unprecedented nominal strain of 0.06%,thereby enabling its utility in accurately discerning the 5μm-height wrinkles in thin films and in monitoring human pulse *** ultra-high sensitivity is attributed to the formation of porous ferroelectret and the efficient load transfer efficiency of continuous lead zirconate titanate ***,when integrated with machine learning techniques,the sensor’s capability to recognize multi-signals enables it to differentiate between 10 types of fine textures with 100%*** structural design in piezoelectric devic.s.enables a more comprehensive perception of mechanical stimuli,offering a novel perspective for enhancing recognition accuracy.

关键词： Flexible piezoelectric filaments Anisotropic Ultra-high sensitivity structural health detection Texture recognition

Alternative strategy for Development of Dielectric calcium copper Titanate‑Based Electrolytes for Low‑Temperature solid Oxide Fuel cells

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Nano-Micro Letters 2025年第1期17卷 310-332页

作者： sajid Rauf Muhammad Bilal Hanif Zuhra Tayyab Matej Veis MAKYousaf shah Naveed Mushtaq Dmitry Medvedev Yibin tian chen Xia Martin Motola Bin Zhu college of Mechatronics and control Engineering Shenzhen UniversityShenzhen 518060People’s Republic of China Department of Inorganic chemistry Faculty of Natural SciencesComenius University BratislavaIlkovicova684215 BratislavaSlovakia Energy storage Joint Research center School of Energy and EnvironmentSoutheast UniversityNanjing 210096People’s Republic of China Hydrogen Energy Laboratory Ural Federal University620002 EkaterinburgRussia Laboratory of Electrochemical Devic.s.Based on solid Oxide Proton Electrolytes Institute of High Temperature Electrochemistry620066 EkaterinburgRussia school of Microelectronics Hubei UniversityWuhan 430062People’s Republic of China

The development of low-temperature solid oxide fuel cells(LT-sOFcs)is of significant importance for realizing the widespread application of *** has stimulated a substantial materials research effort in developing high oxide-ion conductivity in the electrolyte layer of *** this context,for the first time,a dielectric material,cacu_(3)Ti_(4)O_(12)(ccTO)is designed for LT-sOFcs electrolyte application in this *** individual ccTO and its heterostructure materials with a p-type Ni_(0.8)co_(0.15)Al_(0.05)LiO_(2−δ)(NcAL)semiconductor are evaluated as alternative electrolytes in LT-sOFc at 450–550℃.The single cell with the individual ccTO electrolyte exhibits a power output of approximately 263 mW cm^(-2) and an open-circuit voltage(OcV)of 0.95 V at 550℃,while the cell with the ccTO–NcAL heterostructure electrolyte capably delivers an improved power output of approximately 605 mW cm^(-2) along with a higher OcV over 1.0 V,which indicates the introduction of high hole-conducting NcAL into the ccTO could enhance the cell performance rather than inducing any potential short-circuiting *** is found that these promising outcomes are due to the interplay of the dielectric material,its structure,and overall properties that led to improve electrochemical mechanism in ccTO–***,density functional theory calculations provide the detailed information about the electronic and structural properties of the ccTO and NcAL and their heterostructure ccTO–*** study thus provides a new approach for developing new advanced electrolytes for LT-sOFcs.

关键词： LT-sOFcs Dielectric cacu_(3)Ti_(4)O_(12) semiconductor Ni_(0.8)co_(0.15)Al_(0.05)LiO_(2−δ) Ionic conductivity Heterostructure electrolyte

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美国公法域外适用机制及中国因应研究

海南大学学报（人文社会科学版） 2025年第1期43卷 195-206页

作者：田静南开大学法学院天津300071

公法域外适用衍生于国际体系的结构性演变,有着经济全球化下独特的政治、经济与意识形态背景。其在公法域外适用需求的显现、国家主权观念的转换、公法禁忌原则的突破以及法律形式的嬗变上,具备了一定的存在基础。但是近年来,囿于美国... 详细信息

公法域外适用衍生于国际体系的结构性演变,有着经济全球化下独特的政治、经济与意识形态背景。其在公法域外适用需求的显现、国家主权观念的转换、公法禁忌原则的突破以及法律形式的嬗变上,具备了一定的存在基础。但是近年来,囿于美国国际法理念的转变,其由原先对严格属地主义的固守转为对国家利益至上的推崇,因而在公法域外适用上愈发地恣意与专断,使公法域外适用存在严重的法律、外交和道德张力。为应对美国公法域外适用,中国须秉承防御与建设共进的思路。一方面,加强国际合作共同抗衡美国公法域外适用制度的滥用,同时健全中国的反制法律体系;另一方面,梳理总结美国多年来在公法域外适用过程中形成的丰富经验,在此基础上构建完善符合国际法基本原则的中国法域外适用制度。

关键词：域外适用管辖权效果原则公法禁忌

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Recent progress in the applications of presynaptic dopaminergic positron emission tomography imaging in parkinsonism

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Neural Regeneration Research 2025年第1期20卷 93-106页

作者： Yujie Yang Xinyi Li Jiaying Lu Jingjie Ge Mingjia chen Ruixin Yao Mei tian Jian Wang Fengtao Liu chuantao Zuo Key Laboratory of Arrhythmias Ministry of EducationDepartment of Medical GeneticsShanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina Department of Neurology National Research Center for Aging and MedicineNational Center for Neurological Disordersand State Key Laboratory of Medical NeurobiologyHuashan HospitalFudan UniversityShanghaiChina Department of Nuclear Medicine&PET center National Center for Neurological Disordersand National Clinical Research Center for Aging and MedicineHuashan HospitalFudan UniversityShanghaiChina International Human Phenome Institutes(shanghai) ShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of *** review provides a comprehensive summary of the latest developments in the application of presynaptic dopaminergic positron emission tomography imaging in disorders that manifest *** conducted a thorough literature search using reputable databases such as PubMed and Web of *** criteria involved identifying peer-reviewed articles published within the last 5 years,with emphasis on their relevance to clinical *** findings from these studies highlight that presynaptic dopaminergic positron emission tomography has demonstrated potential not only in diagnosing and differentiating various Parkinsonian conditions but also in assessing disease severity and predicting ***,when employed in conjunction with other imaging modalities and advanced analytical methods,presynaptic dopaminergic positron emission tomography has been validated as a reliable in vivo *** validation extends to screening and exploring potential neuropathological mechanisms associated with dopaminergic *** summary,the insights gained from interpreting these studies are crucial for enhancing the effectiveness of preclinical investigations and clinical trials,ultimately advancing toward the goals of neuroregeneration in parkinsonian disorders.

关键词： aromatic amino acid decarboxylase brain imaging dopamine transporter Parkinson’s disease parkinsonism positron emission tomography presynaptic dopaminergic function vesicle monoamine transporter type 2

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中华文化生命体的特征探析

新疆师范大学学报（哲学社会科学版） 2025年第2期46卷 122-127页

作者：秘天一新疆大学马克思主义学院新疆乌鲁木齐830046

中华文化生命体呈现对环境刺激的反应、生长发育、新陈代谢、自我调节和超脱自然选择等特征,具有整体性、连贯性、创新性、开放性与和平性特质。整体性和连贯性确保中华文化在数千年发展中的赓承延续与稳定,通过“天人合一”“和而不同... 详细信息

中华文化生命体呈现对环境刺激的反应、生长发育、新陈代谢、自我调节和超脱自然选择等特征,具有整体性、连贯性、创新性、开放性与和平性特质。整体性和连贯性确保中华文化在数千年发展中的赓承延续与稳定,通过“天人合一”“和而不同”实现内在和谐统一;创新性使中华文化在历史长河中保持强大的生长力,推动中华优秀传统文化现代转型,实现马克思主义中国化的新飞跃;开放性增强了中华文化的适应性和生命力,通过吸收和融合外来优秀文化元素,使中华文化在全球化进程中保持独特性和竞争力,并以开放姿态积极借鉴吸收人类文明一切优秀成果,推动文化守正创新;和平性源于对和谐、和合文化的深刻理解,强调和谐共生、和合共在、和平发展,通过对话与合作解决争端。中华文化生命体在全球化背景下展现出独特的现代价值和全球视野,彰显了中华文化的强大生命力和国际影响力。

关键词：习近平文化思想中华文化生命体两个结合文化新使命中华优秀传统文化