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Evaluation of Formaldehyde as a Potential Cause of Olfactory Dysfunction in Hairdressers

Journal of Power and Energy Engineering 2023年第3期11卷 143-149页

作者： Linda Bitencourt Cabral Mariana Andrade Miyamoto Natália Medeiros Dias Lopes Ellen Cristine Duarte Garcia tiago severo peixe Marco Aurélio Fornazieri Department of Clinical Surgery Universidade Estadual de Londrina Londrina Brazil Medical School Pontifícia Universidade Católica do Paraná Londrina Brazil GEM Center of Excellence in Research Teaching and Health Care Londrina Brazil Department of Clinical and Toxicological Analysis Universidade Estadual de Londrina Londrina Brazil

Objective: The aim of this study was to compare the olfactory function between hairdressers exposed to formaldehyde and unexposed controls, as exposure to toxic agents is a potential cause of olfactory disorders in humans. Hairdressing professionals frequently encounter formaldehyde, a component found in hair products that are known to have various toxic effects on the human body, including alterations in the sense of smell. Methods: A total of 32 hairdressing volunteers exposed to formaldehyde and 32 non-exposed volunteers matched for age, sex, education and smoking status underwent the University of Pennsylvania Smell Identification Test (UPSIT®). Results: The findings demonstrated a decrease in UPSIT® olfactory test scores and a higher degree of olfactory loss among hairdressers exposed to formaldehyde (mean UPSIT® scores: 30.6 vs 35.1, p Conclusion: Occupational exposure of hairdressers to formaldehyde is associated with diminished olfactory function. Education approach and promotion of personal protective equipment usage should be encouraged.

关键词： Formaldehyde Olfaction Disorders Occupational Medicine Toxicology

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Nanotoxicology and Exposure in the Occupational Setting

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Occupational Diseases and Environmental Medicine 2015年第3期3卷 35-48页

作者： tiago severo peixe Elizabeth de Souza Nascimento Katie Larson Schofield Arline S.A.Arcuri Rachel P.Bulcao Departamento de Patologia Análises Clínicas e ToxicológicasUniversidade Estadual de Londrina(UEL)LondrinaBrasil Departamento de Análises Clínicas e Toxicológicas Faculdade de Ciencias Farmaceuticas(FCF)Universidade de Sao Paulo(USP)Sao PauloBrasil The Work Comp Experts(SFM) MinneapolisUSA Coordenacao de Higiene Ocupacional FundacentroMinisterio do Trabalho e EmpregoSao PauloBrasil Faculdade Educacional Araucária(FACEAR) AraucáriaBrasil

Nanotechnology refers to the ability to control the composition of molecules and atoms within the range of 1.00 - 100 nm. At this scale, many materials exhibit novel properties when compared with their micro or macro-sized equivalents, including, for example, chemical reactivity, strength, mobility and solubility. Nanoparticles are prime candidates for toxicity because they possess a much greater surface to volume ratio (i.e. the surface area compared to the volume) than larger particles of that same material;they can have biopersistance and higher oxidant capacity, penetrate epithelium and reach interstitial pulmonary region. In an industrial setting, workers may present the main exposure risk potential among humans, and they may be involved in the entire product life cycle. There are needs to protect public and environmental health and safety. Currently, no standards or regulations exist that apply or refer specifically to nanomaterials impacts.

关键词： Nanotoxicology Occupational Workers Nanoparticles Exposure

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