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Sucrose transporter2 contributes to maize growth,development,and crop yield

Journal of Integrative Plant Biology 2017年第6期59卷 390-408页

作者： Kristen A.Leach thu m.tran Thomas L.Slewinski Robert B.meeley David m.Braun Division of Biological Sciences Interdisciplinary Plant Group Missouri Maize Center University of Missouri Columbia MO 65211 USA Department of Biology Pennsylvania State University University Park PA 16802 USA DuPont Pioneer Research & Development Johnston Iowa 50131 USA

During daylight, plants produce excess photo- synthates, including sucrose, which is temporarily stored in the vacuole. At night, plants remobilize sucrose to sustain metabolism and growth. Based on homology to other sucrose transporter （SUT） proteins, we hypothesized the maize （Zea mays） SUCROSE tranSPORTER2 （ZmSUT2） protein functions as a sucrose/H^＋ symporter on the vacuolar membrane to export transiently stored sucrose. To understand the biological role of ZmSut2, we examined its spatial and temporal gene expression, determined the protein subcellular localization, and characterized loss-of- function mutations. ZmSut2 mRNA was ubiquitously expressed and exhibited diurnal cycling in transcript abundance. Expressing a translational fusion of ZmSUT2 fused to a red fluorescent protein in maize mesophyll cell protoplasts revealed that the protein localized to the tonoplast. Under field conditions, zmsut2 mutant plants grew slower, possessed smaller tassels and ears, and produced fewer kernels when compared to wild-type siblings, zmsut2 mutants also accumulated two-fold more sucrose, glucose, and fructose as well as starch in source leaves compared to wild type. These findings suggest （i） ZmSUT2 functions to remobilize sucrose out of the vacuole for subsequent use in growing tissues; and （ii） its function provides an important contribution to maize development and agronomic yield.

关键词： William J. Lucas, University of California, Davis, USAReceived Dec. 30, 2016 Accepted Feb. 10, 20171 Online on Feb. 16,2017

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Cell-type resolved transcriptomic approaches for dissecting selective vulnerability in neurodgeneration

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Neural Regeneration Research 2024年第7期19卷 1411-1413页

作者： Caleb A.Wood Nicholas m.tran Department of Neuroscience Baylor College of MedicineHoustonTXUSA Department of molecular and Human Genetics Baylor College of MedicineHoustonTXUSA

A common feature among neurodegenerative conditions is that ce rtain neuronal populations are selectively vulnerable to loss(Fu et al.,2018).By corollary,other neurons are selectively resilient,suggesting they may possess unique features that support their survival.U nderstanding the basis of neuronal resilience or vulnerability would provide a logical strategy to identify factors that could be targeted therapeutically.

关键词： selective targeted

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maize Carbohydrate Partitioning Defective33 Encodes an mCTP Protein and Functions in Sucrose Export from Leaves

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molecular Plant 2019年第9期12卷 1278-1293页

作者： thu m.tran Tyler J.mcCubbin Saadia Bihmidine Benjamin T.Julius R.Frank Baker martin Schauflinger Clifford Weil Nathan Springer Paul Chomet Ruth Wagner Jeff Woessner Karen Grote Jeanette Peevers Thomas L.Slewinski David m.Braun Division of Biological Sciences’Interdisciplinary Plant Group Missouri Maize CenterUniversity of MissouriColumbiaMO 65211USA Division of Plant Sciences University of MissouriColumbiaMO 65211USA Electron microscopy Core Facility University of MissouriColumbiaMO 65211USA Department of Agronomy Purdue UniversityWest LafayetteIN 47907USA Department of Plant and microbial Biology University of MinnesotaSaint PaulMN 55108USA NRGene Inc. 8910 University Center Lane\r\n S u ite 400San DiegoCA 92122USA Bayer Crop Science ChesterfieldMO 63017USA National Key Laboratory for Plant Cell Technology Agricultural Genetics InstituteHanoiVietnam

To sustain plant growth,development,and crop yield,sucrose must be transported from leaves to distant parts of the plant,such as seeds and *** identify genes that regulate sucrose accumulation and transport in maize(Zea mays),we isolated carbo/iydrafe part/f/ofi/ngf defecf/Ve33(cpd33),a recessive mutant that accumulated excess starch and soluble sugars in mature *** cpd33 mutants also exhibited chlorosis in the leaf blades,greatly diminished plant growth,and reduced ***33 encodes a protein containing multiple C2 domains and transmembrane *** localization experiments showed the CPD33 protein localized to plasmodesmata(PD),the plasma membrane,and the endoplasmic *** also found that a loss-of-function mutant of the CPD33 homolog in Arabidopsis,QUIRKY,had a similar carbohydrate hyperaccumulation *** labeled sucrose transport assays showed that sucrose export was significantly lower in cpd33 mutant leaves relative to wild-type ***,PD transport in the adaxial-abaxial direction was unaffected in cpd33 mutant ***,transmission electron microscopy revealed fewer PD at the companion cell-sieve element interface in mutant phloem tissue,providing a possible explanation for the reduced sucrose export in mutant ***,our results suggest that CPD33 functions to promote symplastic transport into sieve elements.

关键词： carbohydrate accumulation companion cells phloem, plasmodesmata sieve elements symplastictransport

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Comparative impact behaviours of ultra high performance concrete columns reinforced with polypropylene vs steel fibres

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Defence Technology（防务技术） 2024年第10期40卷 138-153页

作者： Thong m.Pham Harrison Hyde maw K.Kaung Yan Zhuge Duong T.tran Des Vlietstra Tung m.tran UniSA STEMUniversity of South AustraliaMawson LakesSA 5095Australia BG&E Pty Ltd Wellington StreetPerthWA6000Australia Austral Construction Pty Ltd St Georges TerracePerthWA6000Australia Centre for Infrastructural monitoring and Protection(CImP) Curtin UniversityKent StBentleyWA 6102Australia Barchip Australia Pty Ltd U 26 Qualtroughq StreetWoolloongabbaQueensland4102Australia Sustainable Developments in Civil Engineering Research Group Faculty of Civil EngineeringTon Duc Thang UniversityHo Chi Minh City72915Viet Nam

Polypropylene(PP)fibres have primarily used to control shrinkage cracks or mitigate explosive spalling in concrete structures exposed to fire or subjected to impact/blast loads,with limited investigations on capacity *** study unveils the possibility of using PP micro-fibres to improve the impact behaviour of fibre-reinforced ultra-high-performance concrete(FRUHPC)*** show that the addition of fibres significantly improves the impact behaviour of FRUHPC columns by shifting the failure mechanism from brittle shear to favourable flexural *** addition of steel or PP fibres affected the impact responses *** fibres considerably increased the peak impact force(up to 18%)while PP micro-fibres slightly increased the peak(3%-4%).FRUHPC significantly reduced the maximum midheight displacement by up to 30%(under 20impact)and substantially improved the displacement recovery by up to 100%(under 20impact).FRUHPC with steel fibres significantly improved the energy absorption while those with PP micro-fibres reduced the energy absorption,which is different from the effect of PP-macro fibre reported in the *** optimal fibre content for micro-PP fibres is 1%due to its minimal fibre usage and low peak and residual *** study highlights the potential of FRUHPC as a promising material for impact-resistant structures by creating a more favourable flexural failure mechanism,enhancing ductility and toughness under impact loading,and advancing the understanding of the role of fibres in structural performance.

关键词： Ultra high-performance concrete Steel fibre Polypropylene micro-fibre Fibre volume fraction Impact loading Pendulum tests Columns

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An isogeometric approach for nonlocal bending and free oscillation of magneto-electro-elastic functionally graded nanobeam with elastic constraints

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Frontiers of Structural and Civil Engineering 2024年第9期18卷 1401-1423页

作者： thu Huong NGUYEN THI Van Ke tran Quoc Hoa PHAm School of mechanical and Automotive Engineering Hanoi University of IndustryHanoi 100000Vietnam Faculty of mechanical Engineering Le Quy Don Technical UniversityHanoi 100000Vietnam Faculty of Engineering and Technology Nguyen Tat Thanh UniversityHo Chi Minh City 700000Vietnam

This work uses isogeometric analysis(IGA),which is based on nonlocal hypothesis and higher-order shear beam hypothesis,to investigate the static bending and free oscillation of a magneto-electro-elastic functionally graded(mEE-FG)nanobeam subject to elastic boundary constraints(BCs).The magneto-electric boundary condition and the maxwell equation are used to calculate the variation of electric and magnetic potentials along the thickness direction of the *** study is innovative since it does not use the conventional boundary ***,an elastic system of straight and torsion springs with controllable stiffness is used to support nanobeams’beginning and end positions,creating customizable *** governing equations of motion of nanobeams are established by applying Hamilton’s principle and IGA is used to determine deflections and natural frequency *** studies were performed to evaluate the convergence and accuracy of the proposed *** from this,the impact of the input parameters on the static bending and free oscillation of the mEE-FG nanobeam is examined in *** findings could be valuable for analyzing and designing innovative structures constructed of functionally graded mEE materials.

关键词： elastic boundary conditions isogeometric analysis nanobeam via nonlocal theory grading of magneto-electro-elastic functions

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transient response of doubly-curved bio-inspired composite shells resting on viscoelastic foundation subject to blast load using improved first-order shear theory and isogeometric approach

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Defence Technology（防务技术） 2024年第8期38卷 171-193页

作者： thuy tran Thi thu Tu Nguyen Anh Hue Nguyen Thi Hong Nguyen Thi School of mechanical and Automotive Engineering Hanoi University of IndustryHanoiViet Nam Faculty of Technical Fundamental University of Transport TechnologyHanoiViet Nam Faculty of mechanical Engineering Thuyloi University175 Tay SonDong DaHanoiViet Nam

Investigating natural-inspired applications is a perennially appealing subject for scientists. The current increase in the speed of natural-origin structure growth may be linked to their superior mechanical properties and environmental resilience. Biological composite structures with helicoidal schemes and designs have remarkable capacities to absorb impact energy and withstand damage. However, there is a dearth of extensive study on the influence of fiber redirection and reorientation inside the matrix of a helicoid structure on its mechanical performance and reactivity. The present study aimed to explore the static and transient responses of a bio-inspired helicoid laminated composite(B-iHLC) shell under the influence of an explosive load using an isomorphic method. The structural integrity of the shell is maintained by a viscoelastic basis known as the Pasternak foundation, which encompasses two coefficients of stiffness and one coefficient of damping. The equilibrium equations governing shell dynamics are obtained by using Hamilton's principle and including the modified first-order shear theory,therefore obviating the need to employ a shear correction factor. The paper's model and approach are validated by doing numerical comparisons with respected publications. The findings of this study may be used in the construction of military and civilian infrastructure in situations when the structure is subjected to severe stresses that might potentially result in catastrophic collapse. The findings of this paper serve as the foundation for several other issues, including geometric optimization and the dynamic response of similar mechanical structures.

关键词： Blast load modified first-order shear theory Biological composite structures

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Nonlocal isogeometric analysis for bidirectional functionally graded porous curved microbeams with arbitrary boundary conditions

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Acta mechanica Sinica 2024年第8期40卷 194-218页

作者： thu-Huong Nguyen Thi Van Ke tran Van-minh Phung Van Hai Trinh Quoc Hoa Pham Faculty of mechanical Engineering Hanoi University of IndustryHanoi100000Vietnam Faculty of mechanical Engineering Le Quy Don Technical UniversityHanoi100000Vietnam Institute of Vehicle and Energy Engineering Le Quy Don Technical UniversityHanoi100000Vietnam Faculty of Engineering and Technology Nguyen Tat Thanh UniversityHo Chi Minh City700000Vietnam

This research aims to analyze the static bending and free vibration behaviors of bidirectional functionally graded porous(BFGP)curved microbeams with elastic boundary conditions resting on a Pasternak’s elastic foundation in a hygro-thermal *** analysis based on non-uniform rational B-splines,first-order shear deformation theory,nonlocal elasticity theory combined with the modified strain gradient theories,modified Timoshenko beam theory are formulated to depict bending and shear deformations of BFGP curved ***,because using the modified Timoshenko beam theory,this study removes the requirement for a shear correction factor and describes shear stress by zero at the upper and lower cross-sectional sites of the BFGP curved *** from traditional boundary conditions,where the beginning and end positions of a curved beam are connected by an elastic system of straight and torsion *** allows for greater flexibility in controlling the stiffness of the springs to obtain arbitrary *** assess the accuracy and convergence of the proposed approach,validation numerical examples were conducted in the various examples.

关键词： Bidirectional functionally graded porous material Elastic boundary condition Isogeometric analysis Curved microbeams Nonlocal elasticity theory modified strain gradient theory

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The impact of green finance,eco-innovation,renewable energy and carbon taxes on CO_(2) emissions in BRICS countries:Evidence from CS ARDL estimation

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Geoscience Frontiers 2024年第4期15卷 449-458页

作者： muhammad Sadiq Ka Yin Chau Nguyen tran Thai Ha Thi thu Hien Phan Thanh Quang Ngo Pham Quang Huy Carbon Economy Research Center Fuzhou University of International Studies and TradeFuzhou 350202China School of Accounting and Finance Faculty of Business and LawTaylor’s UniversityMalaysia Faculty of Business City University of MacaoTaipaMacaoChina Faculty of Finance and Banking Van Lang UniversityHo Chi Minh CityVietnam Zhejiang Shuren University No.8 Shuren streetHangzhou 310015China School of Government University of Economics Ho Chi Minh City(UEH)Ho Chi Minh City 72407Viet Nam Research Group Public Governance and Developmental Issues University of Economics Ho Chi Minh City(UEH)Ho Chi Minh City 72407Viet Nam Ho Chi minh City University of Economics and Finance(UEF) Ho Chi Minh CityVietnam University of Economics and Human Sciences in Warsaw WarsawPoland

A sharp increase in economic and human development has multiplied the carbon intensity due to which there is a significant need of effective strategies in order to curb carbon ***,the present study aims to examine the effective of green finance,eco-innovation,renewable energy output(REO),renewable energy consumption(REC),and carbon taxes on carbon dioxide(CO_(2))emissions in BRICS countries in the time of ***-sectional autoregressive distributed lag(CS ARDL)is used to test the connection among the *** estimations of CS-ARDL approach validates the effectiveness of green finance,eco-innovation,REO,REC,carbon taxes,and industrialization as the relationship of these factors with carbon emissions is negative in nature in BRICS *** on the evidences,the study recommends the formulation of environmentally friendly practices and advancement in green finances to mitigate carbon emissions.

关键词： Green finance Eco-innovation Renewable energyoutput Carbon taxes Environmental degradation CO_(2)emissions

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Push forward LC-mS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical management

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Journal of Pharmaceutical Analysis 2024年第1期14卷 16-38页

作者： Nguyen Quang thu Nguyen tran Nam Tien Nguyen Thi Hai Yen thuc-Huy Duong Nguyen Phuoc Long Huy Truong Nguyen Department of Pharmacology and PharmacoGenomics Research Center Inje University College of MedicineBusan47392Republic of Korea Department of Chemistry University of EducationHo Chi Minh City700000Viet Nam Faculty of Pharmacy Ton Duc Thang UniversityHo Chi Minh City700000Viet Nam

The spread of tuberculosis(TB),especially multidrug-resistant TB and extensively drug-resistant TB,has strongly motivated the research and development of new anti-TB *** strategies to facilitate drug combinations,including pharmacokinetics-guided dose optimization and toxicology studies of first-and second-line anti-TB drugs have also been introduced and *** chromatography-mass spectrometry(LC-mS)has arguably become the gold standard in the analysis of both endo-and exo-genous *** technique has been applied successfully not only for therapeutic drug monitoring(TDm)but also for pharmacometabolomics *** improves the effectiveness of treatment,reduces adverse drug reactions,and the likelihood of drug resistance development in TB patients by determining dosage regimens that produce concentrations within the therapeutic target *** on TDm,the dose would be optimized individually to achieve favorable *** is essential in generating and validating hypotheses regarding the metabolism of anti-TB drugs,aiding in the discovery of potential biomarkers for TB diagnostics,treatment monitoring,and outcome *** article highlighted the current progresses in TDm of anti-TB drugs based on LC-mS bioassay in the last two ***,we discussed the advantages and disadvantages of this technique in practical *** pressing need for non-invasive sampling approaches and stability studies of anti-TB drugs was ***,we provided perspectives on the prospects of combining LC-mS-based TDm and pharmacometabolomics with other advanced strategies(pharmacometrics,drug and vaccine developments,machine learning/artificial intelligence,among others)to encapsulate in an all-inclusive approach to improve treatment outcomes of TB patients.

关键词： Tuberculosis Therapeutic drug monitoring LC-mS mIPD Pharmacometabolomics Precision medicine

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Tungsten-based nanocatalysts with different structures for visible light responsive photocatalytic degradation of bisphenol A

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Journal of Environmental Sciences 2024年第5期139卷 569-588页

作者： Hai Bang Truong Thi thu Loan Doan Nguyen Tien Hoang Nguyen Van Tam minh Kim Nguyen Le Gia Trung Jin Seog Gwag Nguyen Tien tran Optical materials Research Group Science and Technology Advanced InstituteVan Lang UniversityHo Chi Minh CityViet Nam Faculty of Applied Technology School of TechnologyVan Lang UniversityHo Chi Minh CityViet Nam The University of Da Nang University of Science and Technology54 Nguyen Luong BangDa NangViet Nam The University of Da Nang University of Science and Education459 Ton Duc Thang St.Lien ChieuDa Nang 550000Viet Nam Institute of Veterinary Science and Technology 31ha zoneTrau QuyGia LamHa Noi 12400Viet Nam Department of Physics Yeungnam UniversityGyeongsanGyeongbuk 38541Republic of Korea Center for Advanced Chemistry Institute of Research and DevelopmentDuy Tan University03 Quang TrungDa Nang 550000Viet Nam Faculty of Natural Sciences Duy Tan University03 Quang TrungDa Nang 550000Viet Nam

Environmental pollution,such as water contamination,is a critical issue that must be absolutely ***,three different morphologies of tungsten-based photocatalysts(WO_(3)nanorods,WO_(3)/WS_(2)nanobricks,WO_(3)/WS_(2)nanorods)are made using a simple hydrothermal method by changing the solvents(H_(2)O,DmF,aqueous HCl solution).The as-prepared nanocatalysts have excellent thermal stability,large porosity,and high *** results show all materials have good photocatalytic activity in aqueous media,with WO_(3)/WS_(2)nanorods(NRs)having the best activity in the photodegradation of bisphenol A(BPA)under visible-light *** may originate from increased migration of charge carriers and effective prevention of electron–hole recombination in WO_(3)/WS_(2)NRs,whereby this photocatalyst is able to generate more reactive·OH and·O_(2)^(–)species,leading to greater photocatalytic *** 99.6% of BPA is photodegraded within 60 min when using 1.5 g/L WO_(3)/WS_(2)NRs and 5.0 mg/L BPA at pH ***,the optimal conditions(pH,catalyst dosage,initial BPA concentration)for WO_(3)/WS_(2)NRs are also elaborately *** rod-like heterostructures are expressed as potential catalysts with excellent photostability,efficient reusability,and highly active effectivity in different types of *** particular,the removal efficiency of BPA by WO_(3)/WS_(2)NRs reduces by only 1.5% after five recycling runs and even reaches 89.1%in contaminated lake *** study provides promising insights for the nearly complete removal of BPA from wastewater or different water resources,which is advantageous to various applications in environmental remediation.

关键词： Photodegradation Bisphenol A Tungsten-based nanocatalyst Structure Nanorod

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