检索结果-南通市图书馆

Ethyl acetate extract of Smilax glabra Roxb roots and its major active compound astilbin promote osteoblastogenesis in vitro by upregulating bone cell differentiation-associated genes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2021年第12期11卷 553-560页

作者： Huyen T.T.nguyen minh T.H.nguyen thu X.nguyen Quan M.pham Ha X.nguyen Phuong T.M.nguyen University of Science and Technology of Hanoi Vietnam Academy of Science and TechnologyHanoiVietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoiVietnam Institute of Natural Products Chemistry Vietnam Academy of Science and TechnologyHanoiVietnam Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoiVietnam

Objective:To investigate the osteoblastogenic activity of the ethyl acetate(EtOAc)extract of Smilax glabra Roxb roots and its major active compound ***:Astilbin was isolated from EtOAc extract using silica gel chromatography combined with fraction *** structure of astilbin was determined by analysis of the spectroscopic data in comparison with the *** method was used to detect the *** phosphatase(ALP)activity was determined by the spectrophotometric method at 405 nm using p-nitrophenyl phosphate as a *** deposition was stained with alizarin red-S,distained with cetylpyridium chloride,and quantified at 562 *** silico model for astilbin-ALP interaction was analyzed using AutoDock *** changes in expression of osteoblast differentiation related genes were determined using quantitative real-time ***:Both the EtOAc extract and astilbin had no toxicity toward osteoblast MC3T3-E1 cells at 5.0,10,25,and 50μg/*** 25μg/mL,they enhanced ALP activity and mineralization of osteoblasts up to 30%and 55%for the EtOAc extract and 22%and 41%for astilbin,*** docking analysis of astilbin-ALP interaction revealed Arg167,Asp320,His324,and His437 were key residues participating in hydrophobic interaction;meanwhile,His434 and Thr436 residues were involved in hydrogen bond formation in the active site of human tissue-nonspecific ***,the expression level of genes opn,col1,osx,and runx2 were up-regulated in astilbin treated samples with the fold changes as 2.2;3.7;4.1;2.3,respectively at 10μg/mL(P<0.05).Conclusions:The EtOAc extract and its major compound astilbin exhibit osteoblastogenic activity by up-regulating important markers for bone cell *** could be a new and promising osteogenic agent with dual actions for therapeutic applications.

关键词： Smilax glabra Roxb Astilbin Cytotoxicity Osteogenesis Osteoblast Ethyl acetate extract

Promoting sustainable consumption and circular economy: the intention of Vietnamese youth consumers to purchase products made from recycled plastics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Simultaneous Quantitative Analysis of Five Components in Angelica sinensis and Angelica acutiloba Acclimatized Growing in Vietnam by High-Performance Liquid Chromatography with Photodiode Array Detector

中国人口资源与环境(英文版) 2024年第2期 194页

作者： Hong Thi thu nguyen

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

World Journal of Traditional Chinese Medicine 2021年第1期7卷 6-10页

作者： Thi minh Tam pham Thi thu Cuc Le Van Thanh nguyen Viet Hung Tran Departments of Microbiology Institute of Drug Quality ControlHo Chi Minh City Departments of Instrumental Analysis Institute of Drug Quality ControlHo Chi Minh City Institute of Drug Quality Control Ho Chi Minh City Faculty of Pharmacy Nguyen Tat Thanh UniversityHo Chi Minh CityVietnam

Background:Chinese Danggui(Angelica sinensis)and Japanese Danggui(Angelica acutiloba)are evaluated as the same in using and critical of quality control in Vietnamese *** Vietnam,Japanese Danggui were acclimatized and cultivated in several regions in recent *** the huge climatic difference between Vietnam and Japan,Japanese Danggui grows very well in ***,there are no studies to assess the overall quality of this medicinal *** and Objectives:The aim of this study is to develop a method to identify and assay simultaneously 5 component compounds of these crude herbs:chlorogenic acid,ferulic acid,scopoletin,xanthotoxin and ligustilide by high-performance liquid chromatography with photodiode array detector(HPLC-PDA).Materials and Methods:The procedure was optimized by using column Phenomenex Gemini 5μm PR C18,15 x 4,6 mm with the detection wavelength set at 321 nm for detector PDA and mobile phase was composed of(A)ACN and(B)aqueous solution 1%of acid acetic using a gradient *** were performed at 30°C with a flow rate of 1.0 mL/***:The developped method were fully validated for linearity,accuracy,recovery and met the validation requirements,proved practical applicability for the quality control of these herbs and related ***:The method was successfully applied to the quantification of five markers simultaneously from collected samples.

关键词： Chlorogenic acid Danggui ferulic acid ligustilide scopoletin xanthotoxin

Anti-inflammatory effects of alkaloid enriched extract from roots of Eurycoma longifolia Jack

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2019年第1期9卷 18-23页

作者： Dao Thi Thanh Hien Tran Phi Long Tran Phuong Thao Jeong-Hyung Lee Duong thu Trang nguyen Thi thu minh pham Van Cuong Do Thi Ngoc Lan nguyen Hai Dang nguyen Tien Dat Deparment of Traditional Pharmacy Hanoi University of Pharmacy Department of Biochemistry College of Natural Sciences Kangwon National University Advanced Center for Bio-organic Chemistry Institute of Marine Biochemistry Vietnam Academy of Science and Technology National Institute of Drug Quality Control Center for Research and Technology Transfers

Objective: To examine the in vitro and in vivo anti-inflammatory effects of the alkaloid enriched extract(ELA) from the roots of Eurycoma longifolia. Methods: The in vitro antiinflammatory effects of ELA were evaluated by examining its inhibitory activities against nitric oxide(NO) production and inducible nitric oxide synthase(iN OS) and cyclooxygenase2(COX-2) expressions in lipopolysaccharide(LPS)-stimulated RAW264.7 cells. The level of NO produced in the culture media was determined by Griess method. The i NOS and COX-2 protein expressions were analyzed by Western blot. The in vivo effect of ELA was evaluated on LPS-induced septic shock in mice model. Mice mortality was monitored for5 days after injection of LPS. The chemical contents of the ELA were determined by using various chromatographic and spectroscopic techniques. Results: The ELA was found to exhibit a significant anti-inflammatory effect in both in vitro and in vivo models. The results demonstrated that ELA dose-dependently inhibited LPS-induced NO production as well as the protein iN OS and COX-2 expressions. In the septic shock model, ELA dose-dependently protected mice from LPS-induced mortality. Further study on the isolated components of ELA indicated that 9,10-dimethoxycanthin-6-one may contribute significantly to the antiinflammatory effects of the extract. Conclusions: These results suggest that ELA exhibits the anti-inflammatory activity via suppression of pro-inflammatory mediators such as NO, iN OS,and COX-2 and protects mice from LPS-induced mortality in septic shock model.

关键词： Eurycoma longifolia Anti-inflammation Alkaloid 9,10-dimethoxycanthin-6-one

Synthesis and characterization of NaYF4:Yb3+,Er3+@silica-N=folic acid nanocomplex for bioimaginable detecting MCF-7 breast cancer cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2019年第11期37卷 1183-1187页

作者： Ha Thi Phuong Tran thu Huong Le Thi Vinh Hoang Thi Khuyen Do Thi Thao nguyen Thanh Huong pham Thi Lien Le Quoc minh Institute of Materials Science Vietnam Academy of Science and Technology18 Hoang Quoc VietCau GiayHanoiViet Nam Graduate University of Science and Technology-Vietnam Academy of Science and Technology 18 Hoang Quoc VietCau GiayHanoiViet Nam Department of Chemistry Hanoi Medical University1-Ton That TungDong DaHanoiViet Nam Department of Chemistry Hanoi University of Mining and Geology18-Pho LienBac Tu LiemHanoiViet Nam Institute of Biotechnology Vietnam Academy of Science and Technology18-Hoang Quoc VietCau GiayHanoiViet Nam Duy Tan University K7/25 Quang TrungDa NangViet Nam

Upconversion nanophosphors are new promising nanomaterials to be used as biolabels for detection and imaging of cancer *** nanophosphors absorb long-wavelength excitation radiation in the infrared or near infrared region and emit shorter wavelength,higher energy radiation from ultraviolet to *** this paper,we studied the hydrothermal method and optical properties of the functionalized NaYF4:Yb^3+,Er^3+for biomedical *** synthesis,these NaYF4:Yb^3+,Er^3+nanophosphors were functionalized with aminosilanes and folic *** acid binds to the folate receptor on the surface of MCF-7 breast cancer cells and this binding promotes internalization of the nanophosphors via *** sizes of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA(folic acid)nanophosphors can be controlled with length of the rod about 300-800 nm and diameter of the rod about 100-200 *** structure of NaYF4:Yb^3+,Er^3+is in hexagonal crystal *** photo luminescence(PL)spectra of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA nanophosphors were *** nanophosphors emit in red color with the strongest band at 650 nm under 980 nm *** result can provide NaYF4:Er^3+,Yb^3+@silica-N=FA complex for developing fluorescence label and image tool in cancer biology and medicine.

关键词： Upconversion luminescence NaYF4:Yb^3+,Er^3+ Nanophosphors Bioimaging Cancer cell Rare earths

Land subsidence prediction for a new urban mass rapid transit line in Hanoi

在线全文

学校读者我要写书评

暂无评论

Underground Space 2020年第2期5卷 93-104页

作者： pham Huy Giao Vu Thi Hue nguyen Dang Han nguyen Thi Hai Anh nguyen Ngoc minh Asian Institute of Technology BangkokThailand Institute of Foundation and Underground FECONHanoiViet Nam Sonhai JSC Viet Nam

The rapidly increasing population,urbanization,and industrialization of Hanoi city in the last few decades have necessitated the urgent development of a new underground public transport infrastructure such as the urban mass rapid transit(UMRT)system that is now under ***,concerns on the possible effects of land subsidence on the to-be-constructed and operated UMRT lines must be *** of the difficulties while assessing land subsidence in Hanoi is the insufficient subsidence monitoring ***,a good geotechnical characterization of the subsoil profile and proper numerical analysis can help predict groundwater pumping-induced subsidence *** UMRT line No.2 that was selected for this study is special as it runs across the old quarter downtown,located at the very heart of Hanoi *** this paper,the Hanoi aquifer system,groundwater extraction,and subsidence monitoring network of Hanoi are reviewed *** data from 30 investigation boreholes were analyzed to characterize the subsoil profile underlying a segment of the UMRT line No.2 that consists of both elevated and underground *** soil layers were identified up to a depth of 50 m,including a compressible soft clay layer 10-15 m thick that is supposed to be most vulnerable to subsidence by groundwater *** on the long-term groundwater monitoring data,one-dimensional finite element method(FEM)consolidation analyses were carried out for three drawdown boundary conditions of 5,10,and 15 m and yielded a total subsidence of 0.15,0.35,and 0.5 m,respectively,after 25 years with 1994 as the reference *** results of this study confirmed that land subsidence in particular should be considered in the construction and maintenance of the UMRT lines in Hanoi,in particular for underground sections that are founded on soft to medium clay layers.

关键词： Hanoi aquifer system Groundwater pumping Land subsidence UMRT line Geotechnical characterization

Hybrid model to optimize object-based land cover classification by meta-heuristic algorithm:an example for supporting urban management in Ha Noi,Viet Nam

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2019年第10期12卷 1118-1132页

作者： Quang-Thanh Bui Manh pham Van nguyen Thi thuy Hang Quoc-Huy nguyen nguyen Xuan Linh pham minh Hai Tran Anh Tuan pham Van Cu Center for Applied Research in Remote sensing and GIS(CARGIS) VNU University of ScienceHa NoiViet Nam VNU University of Science Ha NoiViet Nam Vietnam Institute of Geodesy and Cartography Ha NoiViet Nam Ministry of Education and Training Ha NoiViet Nam

This study proposed a novel object-based hybrid classification model named GMNN that combines Grasshopper Optimization Algorithm(GOA)and the multiple-class Neural network(MNN)for urban pattern detection in Hanoi,*** bands of SPOT 7 image and derivable NDVI,NDWI were used to generate image segments with associated attributes by PCI Geomatics *** segments were classified into four urban surface types(namely water,impervious surface,vegetation and bare soil)by the proposed ***,three training and validation datasets of different sizes were used to verify the robustness of this *** all tests,the overall accuracies of the classification were approximately 87%,and the Area under Receiver Operating Characteristic curves for each land cover type was ***,the performance of this model was examined by comparing several statistical indicators with common benchmark *** results showed that GMNN out-performed established methods in all comparable *** results suggested that our hybrid model was successfully deployed in the study area and could be used as an alternative classification method for urban land cover *** a broader sense,classification methods will be enriched with the active and fast-growing contribution of metaheuristic algorithms.

关键词： Urban remote sensing object-based classification neural network grasshopper optimization algorithm

Effect of heating time on structural,morphology,optical,and photocatalytic properties of g-C3N4 nanosheets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2020年第5期29卷 504-508页

作者： nguyen Manh Hung Le Thi Mai Oanh Lam Thi Hang pham Do Chung pham Thi Duyen Dao Viet Thang nguyen Van minh Center for Nano Science and Technology Hanoi National University of Education136 Xuan Thuy RoadCau Giay DistrictHanoi100000Vietnam Department of Physics Hanoi National University of Education136 Xuan Thuy RoadCau Giay DistrictHanoi100000Vietnam Faculty of Basic Sciences Hanoi University of Natural Resources and Environment41A Phu Dien RoadNorth Tu LiemHanoi100000Vietnam Hanoi University of Mining and Geology Duc Thang wardNorth Tu Liem DistrictHanoi100000Vietnam Military science Academy 322 Le Trong Tan streetDinh CongHoang MaiHanoi100000Vietnam

Effect of heating time on the structural,morphology,optical,and photocatalytic properties of graphitic carbon nitride(g-C3N4)nanosheets prepared at 550℃in Ar atmosphere is *** investigations are carried out by using x-ray diffraction(XRD),scanning electron microscopy(SEM),Fourier-transform infrared spectroscopy(FTIR),UV-vis absorption,and photoluminescence(PL).At a heating temperature of 550℃,g-C3N4 nanocrystals are formed after 0.5 h and become more orderly as the heating time *** surface area of the g-C3N4 nanosheets significantly increases as the preparation time *** g-C3N4 prepared in 2.5 h shows the highest photocatalytic performance,decomposing completely 10 ppm RhB solution under xenon lamp irradiation for 2.0 h.

关键词： nanosheets photocatalytic heating time Ar atmosphere

Isolation and Identification of Two Flavonoid Compounds from Acclimatized Angelica acutiloba Kitagawa Growing in Vietnam

在线全文

学校读者我要写书评

暂无评论

World Journal of Traditional Chinese Medicine 2022年第3期8卷 413-416页

作者： Thi minh Tam pham Thi thu Cuc Le Viet Hung Tran Van Thanh nguyen Department of Microbiology Institute of Drug Quality ControlDepartment of Analytical Chemistry and Quality ControlUniversity of Medicine and PharmacyHo Chi Minh CityVietnam Department of Analytical Chemistry and Quality Control Nguyen Tat Thanh UniversityHo Chi Minh CityVietnam Department of Microbiology Institute of Drug Quality ControlHo Chi Minh CityVietnam

Traditional Vietnamese Medicine has its own development based on the local endemic herbs,but it also inherits from Traditional Chinese Medicine using Chinese herbal *** the history of cultural exchange between two countries,the adoption of Chinese Danggui,Angelica sinensis(Oliv.)Diels.,has been made by Vietnamese traditional medicine practitioners for a long ***,the acclimatization has never been *** Danggui,or Angelica acutiloba Kitagawa,is recently being acclimatized and cultivated in several Vietnamese *** the huge climate change between the two countries,the herb adapted exquisitely well to the humid tropical ***,so far,there are no studies that have evaluated the effect of acclimatization on the overall quality of this medicinal *** aim of our study is screening secondary metabolites of this acclimatized herb for new natural compound(s),if *** analysis of flavonoid fraction from this herb led to the identification of two known compounds which previously have not been isolated from this species *** detection showed that the herb has reacted to the new environment.

关键词： Abiotic stress Angelica acutiloba danggui isoquercitrin rutin