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Traditional uses,phytochemistry and pharmacology of Clerodendron glandulosum Coleb - a review

Asian Pacific Journal of Tropical Medicine 2012年第1期5卷 1-6页

作者： Ravirajsinh N Jadeja Menaka C Thounaojam thouchom brojendro singh Ranjitsinh V Devkar AV Ramachandran Division of Phytotherapeutics and Metabolic Endocrinology Department of ZoologyFaculty of ScienceThe MS University of BarodaVadodara-390002GujaratIndia Department of Chemistry Oriental CollegeImphal-795001ManipurIndia

Present review for the first time provides a complete botanical description and information on ethnomcdicinal uses of Clerodendron ***(CG:***).Recent studies conducted from our laborator) provide pharmacological evidence for its anti-hypertensive,antidiabetic and anti-obesity ***,its beneficial potential in preventing in vitro and in vivo non-alcoholic steatohepatitis and atherosclerosis and potent hcpatoprotective and free radical scavenging abilities along with its acute and sub- chronic toxicologiesl evaluations are also reported from our *** keeping with its traditional uses,CG extract was capable of ameliorating experimentally induced hypertension,diabetes and *** beneficial potential against NASH induced oxidative stress and atherosclerosis can be attributed to its potent free radical scavenging ***—toxic nature of CG leaf extract further provides added merit to its reported pharmacological *** present review summarizes the pioneering scientific evidence for the pharmacological effects of CG against related metabolic disorders like hypertension,diabetes and obesity along with anti oxidant potential and beneficial elicits against non alcoholic steatohepatitis.

关键词： Clerodendron glandulosum.Coleb Hypertension Hyperlipidemia Insulin resistance Obesity Atherosclerosis

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Angiosarcoma Thyroid: Case Report and Review of Literature

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Case Reports in Clinical Medicine 2014年第3期3卷 105-109页

作者： Aayush Mittal Sunil Kumar Yumlembem brojendro singh Sunil Garg Department of Otorhinolaryngology—Head & Neck Surgery Hind Institute of Medical Sciences and Shekhar Hospital Lucknow India Department of Otorhinolaryngology—Head & Neck Surgery Lady Hardinge Medical College New Delhi In-dia

Objective: To describe a rare case of angiosarcoma thyroid in Indian subcontinent with its successful management. Case report: A 60-year-old male with swelling in neck for 20years with sudden increase in the size during last 3 months. Fine needle aspiration cytology suggested anaplastic carcinoma. The patient underwent total thyroidectomy with central and lateral neck dissection. On histopathology, the diagnosis of angiosarcoma was suspected. Immunohisto chemistry confirmed the diagnosis of angiosarcoma. Post-operative chemoradiation was given with no recurrence at 10 months of follow up. Conclusion: Though rare, angiosarcoma should be included as differential diagnosis in cases of long standing goiters with recent rapid increase in size. Immunohistochemistry is crucial for diagnosis and should be considered in these patients. Early and prompt diagnosis will help in providing curative treatment in such patients.

关键词： Angiosarcoma Thyroid

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