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Effectiviness, Safety and Satisfaction in Teleurology

Open Journal of Urology 2022年第7期12卷 383-393页

作者： thome barros junior Marcos Kalaf Farah Albeny Igor José Caetano De Lima Guilherme Bastos Palitot De Brit Moacir Cavalcante De Albuquerque Neto Fábio Oliveira Vilar Federal University of Pernambuco Recife Brazil Hospital of Clinics of Federal University of Pernambuco Recife Brazil

Introduction: Telemedicine has been used as a tool for improving access to health services worldwide. The aim of the present study is thus to evaluate the effectiveness of urological consultation by videoconference, perceptions regarding safety on the part of medical teams providing video consultation services and patient satisfaction after a urological appointment. Materials and Methods: A cross-sectional, observational, and analytical study was carried out with 50 volunteers referred from the basic health unit for a urology appointment. All patients were evaluated remotely by videoconference and in person by different urology teams. Results: The study revealed that effectiveness in terms of the degree of match between diagnoses performed by video consultation and those performed in person was 92%. The urology team’s perception regarding safety, measured using an in-house safety questionnaire, was high for both videoconferencing and in-person consultations and there was no statistical difference between the two (overall safety score for video consultation compared to in-person consultation was 9.7 ± 0.8 compared to 9.6 ± 0.8 and the p-value was 0.3 for Student’s t-test). Patient satisfaction with the appointment was similarly high for both groups, averaging 9.72 ± 0.4 among patients who attended a video consultation and 9.82 ± 0.4 among those whose consultation was conducted in person, with a p-value of 0.10478 for Student’s t-test. Conclusion: Video consultation in urology is an effective way to perform diagnoses, with high levels of perceived safety among urologists and high satisfaction rates among patients.

关键词： Urology Telemedicine Telecommunications Appointments and Schedules

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The Aging Bladder in Females Evaluated by Urodynamics

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Open Journal of Urology 2017年第3期7卷 54-64页

作者： M. C. de Albuquerque Neto Leslie Clifford Noronha Araujo thome Decio Pinheiro barros junior Joao Luiz Amaro Flavia Cristina Morone Pinto Fabio de Oliveira Vilar Salvador Vilar Correia Lima Urologic Department Clinical Hospital Federal University of Pernambuco UFPE Recife Brazil Urologic Service Botucatu Medical School Paulista State University UNESP Botucatu Brazil Postgraduate Program in Surgery Department of Surgery Center for Health Sciences Federal University of Pernambuco UFPE Recife Brazil

Aim: To determine whether bladder functions deteriorate with age. Methods: Data contained in electronic medical record (INFOMED?) were used in this institutional retrospective review. Analysis was done on the urodynamic studies in women over 18 years old conducted between May 2011 and November 2015. Patients with previous history of pelvic surgery or radiotherapy, neurological disease, vaginal prolapse greater than grade I, congenital urogenital malformations, urinary obstructive disease, diabetes, or the use of any medication that could interfere with bladder function were excluded from the analysis. The urodynamic parameters analyzed were the Maximum Cystometric Capacity (MCC), Voiding Volume (VV), Maximum Flow (Qmax), Bladder Compliance (BC), Detrusor Pressure at Maximum Flow (PdetQmax), Bladder Contractility Index (BCI), Bladder Voiding Efficiency (BVE) and Post-Void Residual Urine Volume (PVR). Patients were further stratified in five groups according to age (A—18 to 40;B—41 to 50;C—51 to 60;D—61 to 70;E—over 70 years old). Results: Out of 3103 urodynamic studies analyzed, 719 were eligible for the study. The average age of patients was 49.3 (+13.2) years old and in all evaluated parameters, statistically significant correlation between age and decline of bladder function was obtained (p Conclusions: This study showed a decline in bladder storage function (reduction in MCC and BC) and in bladder emptying function (reduction in Qmax, PdetQmax, VV, BCI and BVE with an increase in PVR) with age.

关键词： Aging Urinary Bladder Diseases Urinary Bladder Neurogenic Overactive Urodynamics

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The assessment of climatic,environmental,and socioeconomic aspects of the Brazilian Cerrado

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Ecological Processes 2023年第1期12卷 274-285页

作者： Washington Luiz Félix Correia Filho JoséFrancisco de Oliveira-Júnior Dimas de barros Santiago Hazem Ghassan Abdo Hussein Almohamad Ahmed Abdullah Al Dughairi Carlos Antonio da Silva junior Postgraduate Program in Environmentrics(PPGAmb) Institute of MathematicsStatisticsand Physics(IMEF)Federal University of Rio Grande(FURG)Rio GrandeRio Grande do Sul 96203-900Brazil Institute of Atmospheric Sciences(ICAT) Federal University of Alagoas(UFAL)MaceióAlagoas 57072-260Brazil Postgraduate Program in Biosystems Engineering(PGEB) Federal Fluminense University(UFF)NiteróiRio de Janeiro 24220-900Brazil Postgraduate Program in Meteorology Unidade Acadêmica de Ciências Atmosféricas(UACA)Federal University of Campina Grande(UFCG)Campina GrandeParaíba 58429-140Brazil Geography Department Faculty of Arts and HumanitiesTartous UniversityTartousSyria Geography Department Faculty of Arts and HumanitiesDamascus UniversityDamascusSyria Geography Department Faculty of Arts and HumanitiesTishreen UniversityLat-takiaSyria Department of Geography College of Arabic Language and Social StudiesQassim UniversityBuraydah 51452Saudi Arabia Departamento de Geografia State University of Mato Grosso(UNEMAT)SinopMato Grosso 78555-000Brazil

Background The Cerrado is the most biodiverse savanna and maintains other *** of its significance,this paper evaluated the Brazilian Cerrado’s climatic,environmental,and socioeconomic aspects using remote sensing data and spatial statistics(correlation analysis and principal components analysis—PCA).Following the measures of sample adequacy(MSA)and Kaiser–Meyer–Olkin(KMO)tests,seventeen variables were *** The MSA revealed that the dataset had a good quality(0.76),and nine variables were selected:elevation,evapotranspiration,active fires,Human Development Index(HDI),land use and land cover(LULC;shrubland and cropland/rainfed),rainfall(spring and autumn),and *** correlation matrix indicated a positive(negative)association between HDI and autumn rainfall(HDI and active fires)with a value of 0.77(-0.55).The PCA results determined which three principal components(PC)were adequate for extracting spatial patterns,accounting for 68.02%of the total variance with respective values of 38.59%,16.89%,and 12.5%.Due to economic development and agribusiness,Cerrado’s northern(central,western,and southern)areas had negative(positive)score HDI values,as shown in ***(rainfall—spring and fall)and environmental(cropland/rainfed and shrubland)aspects dominated the PC2,with negative scores in northern and western portions due to the transition zone between Amazon and Cerrado biomes caused by rainfall *** the other hand,environmental aspects(LULC-shrubland and elevation)influenced the PC3;areas with high altitudes(>500 m)received a higher *** Agricultural expansion substantially affected LULC,leading to deforestation-caused suppression of native vegetation.

关键词： Environment Agribusiness Active fire Human Development Index Land use and land cover

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Prognosis of forest production using machine learning techniques

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Information Processing in Agriculture 2023年第1期10卷 71-84页

作者： Jeferson Pereira Martins Silva Mayra Luiza Marques da Silva Adriano Ribeiro de Mendonca Gilson Fernandes da Silva Antoˆnio Almeida de barros junior Evandro Ferreira da Silva Marcelo Otone Aguiar Jeangelis Silva Santos Nı´vea Maria Mafra Rodrigues Federal University of Espirito Santo UFESDepartment of Forestry and Wood ScienceAvenue Governor Lindemberg31629550-000 Jeroˆnimo MonteiroESBrasil b Departamento de Cieˆncias Agra´riasUniversidade Federal de Sa o Joa del-Rei Sete Lagoas CampusHighway MG 424-Km 47Sete LagoasMinas Gerais 35701-970Brazil Federal University of Para(UFPA) University Campus of AltamiraStreet Cel.Jose Porfırio2515Sa o Sebastiao68372-040 AltamiraPABrazil

Forest production and growth are obtained from statistical models that allow the generation of information at the tree or forest stand *** the use of regression models is common in forest measurement,there is a constant search for estimation procedures that provide greater ***,machine learning techniques have been used with satisfactory performance in measuring ***,methods such as Adaptive NeuroFuzzy Inference System(ANFIS)and Random Forest are relatively poorly studied for predicting the volume of wood in eucalyptus plantations in ***,it is essential to check whether these techniques can provide gains in terms of ***,this study aimed to evaluate the use of Random Forest and ANFIS techniques in the prognosis of forest *** data used come from continuous forest inventories carried out in stands of eucalyptus *** data were divided into 70%for training and 30%for *** algorithms used to generate rules in ANFIS were Subtractive Clustering and ***,training was done with the hybrid algorithm(descending gradient and least squares)with the number of seasons ranging from 1 to *** RFs were trained,varying the number of trees from 50 to 850 and the number of observations by five leaves to *** neural networks and decision trees were also trained to compare the feasibility of the *** evaluation of the estimates generated by the techniques for training and validation was calculated based on the following statistics:correlation coefficient(r),relative Bias(RB),and the relative root mean square error(RRMSE)in *** general,the techniques studied in this work showed excellent performance for the training and validation data set with RRMSE values*** RF presented inferior statistics about the ANFIS for the prognosis of forest *** Subtractive Clustering(SC)and Fuzzy-C-Means(FCM)algorithms provide accurate baseline

关键词： Artificial Intelligence Ensemble Learning Forest Measurement Forest inventory Artificial Neural Networks Regression

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Acute kidney injury in leptospirosis:Overview and perspectives

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Asian Pacific Journal of Tropical Medicine 2018年第10期11卷 549-554页

作者： Geraldo Bezerra da Silva junior Nattachai Srisawat Gabriela Studart Galdino ênio Sima Macedo JoséReginaldo Pinto Geysa Maria Nogueira Farias Renan Lima Alencar Roberto da Justa Pires Neto Elvino JoséGuardao barros Elizabeth De Francesco Daher Medical Sciences and Public Health and Graduate Programs School of Medicine Health Sciences Center University of Fortaleza Excellence Center for Critical Care Nephrology Division of Nephrology Department of Medicine Chulalongkorn University Collaborating CRISMA faculty member Department of Critical Care Medicine Univeristy of Pittsburgh School of Medicine Medical Sciences and Public Health Graduate Programs Department of Internal Medicine School of Medicine Federal University of Ceara Department of Internal Medicine School of Medicine Federal University of Rio Grande do Sul

Leptospirosis is a bacterial disease disseminated through the centuries in the whole world which causes symptoms that go from self-limited diseases to hemorrhagic manifestations and organ failure, including acute kidney injury(AKI), composing the severe disease known as the Weil's syndrome. Mortality rates varies according to the clinical presentation and usually increases when kidney injury is present, and is even higher in the setting of pulmonary hemorrhage. There are recent advances in the search for novel biomarkers of renal involvement and early detection of AKI in leptospirosis, as well as in its pathophysiology. We review in this article the clinical aspects of leptospirosis-associated AKI and the perspectives for future research.

关键词： Leptospirosis Acute kidney injury Perspectives Bacterial infections

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Epidemiological Profile of Mental Health Program Patients in a Health Unit

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Open Journal of Psychiatry 2020年第1期10卷 15-24页

作者： Amanda Maués Ramos Elisa Maria Novaes barros Juliana Manoella Monteiro de Oliveira Francisco Ipslon Terezo Rosas junior Andrew Moraes Monteiro Vanessa Novaes barros Universidade do Estado do Pará (UEPA) Belém Brazil Universidade Federal do Pará (UFPA) Belém Brazil Neurology/Neuroscience from UNIFESP Estacio de Castanhal University Castanhal Brazil

Aim: To verify the epidemiological profile of patients enrolled in the Mental Health Program at a Family Health Unit, as well as the most prevalent disorders, age and comorbidities. Methods: After analyzing the medical records, the following variables were obtained: diagnosis of mental health status, gender, age group, associated comorbidities and medication in use. Results: There was a prevalence of 61.3% in women and 38.7% in men;patients aged 30 to 39 years were the most affected (22.6%);the most common disorders were epilepsy (36%), depression (14%), anxiety disorder (8.6%) and schizophrenia (8.6%);the most common comorbidities were systemic arterial hypertension (30%) and insomnia (15%) and the most commonly used psychotropic drugs were amitriptyline, carbamazepine and phenobarbital (10.2% each). Conclusion: There was a high prevalence of females, mainly at 30 to 39 years old and the most prevalent diagnoses were epilepsy, depression and anxiety disorder. About medications, antidepressants and anticonvulsants were the most prescribed.

关键词： Mental Health Mental Disorders Comorbidity Epidemiology Prevalence Primary Health Care

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Comparison of Three Experimental Models for Rat Osteoarthritis Induction

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Journal of Biosciences and Medicines 2016年第12期4卷 62-69页

作者： Henrique Ribeiro Rodrigues-Neto Edilson Ferreira Andrade-junior Denilson Jose Silva Feitosa-junior André Lopes Valente Thiago Cesar Xavier Bianca Caroline do Nascimento Alho Renan Kleber Costa Teixeira Fabio Vidal Moriya Rui Sérgio Monteiro de barros Department of Orthopaedics and Traumatology Porto Dias Hospital Bel&eacute m Brazil Experimental Surgery Laboratory Par&aacute State University Bel&eacute m Brazil

Background: Osteoarthritis is a slowly progressive and debilitating disease with high prevalence in adult population. Knee is one of the joints most affected by this disorder. There are several models for animals’ osteoarthritis induction, however it is not identified any paper that compares these techniques. The present study was aimed to define the most appropriate model for rats osteoarthritis induction. Material and Methods: 40 Wistar rats were distributed into 4 groups of 10 animals each: normality group (NG);meniscectomy group (MG);quinolone group (QG) and iodoacetate group (IG). Radiographic images of the rat’s knees were analyzed as well as the amount of chondrocytes in the epiphyseal and articular cartilage. Results: In the radiographic analysis, there was a low correlation between the raters. Regarding the amount of chondrocytes in the epiphyseal cartilage, it was noticed that the IG and QG groups had fewer chondrocytes than NG, in contrast to MG that reported similar results to normality (p > 0.05). There was no significant difference between IG and QG groups (p > 0.05). Regarding the amount of chondrocytes in articular cartilage, it was noticed that the IG group showed fewer chondrocytes than NG (p 0.05). There was no significant difference between QG and MG groups (p > 0.05). Conclusion: Intraarticular injection of iodoacetate in rats is the model with greatest effect on reduction of chondrocytes amount.

关键词： Osteoarthritis Knee Joint Experimental Arthritis Animal Disease Models Rats

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Epigenetic regulation of TP53 is involved in prostate cancer radioresistance and DNA damage response signaling

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Signal Transduction and Targeted Therapy 2023年第11期8卷 5404-5416页

作者： Catarina Macedo-Silva Vera Miranda-Gonçalves Nuno Tiago Tavares Daniela barros-Silva Joana Lencart João Lobo Ângelo Oliveira Margareta PCorreia Lucia Altucci Carmen Jerónimo Cancer Biology&Epigenetics Group Research Center of IPO Porto(CI-IPOP)/CI-IPOP@RISE(Health Research Network)Portuguese Oncology Institute of Porto(IPO-Porto)/Porto Comprehensive Cancer Center Raquel Seruca(Porto.CCC)R.Dr.António Bernardino de Almeida4200-072PortoPortugal Department of Precision Medicine University of Campania“Luigi Vanvitelli”80138NaplesItaly Department of Pathology and Molecular Immunology ICBAS-School of Medicine&Biomedical SciencesUniversity of PortoR.Jorge de Viterbo Ferreira 2284050-313PortoPortugal Medical Physics Radiobiology and Radiation Protection Group-Research Center of IPO Porto(CI-IPOP)/CI-IPOP@RISE(Health Research Network)Portuguese Oncology Institute of Porto(IPO-Porto)/Porto Comprehensive Cancer Center Raquel Seruca(Porto.CCC)R.Dr.António Bernardino de Almeida4200-072PortoPortugal Department of Medical Physics Portuguese Oncology Institute of Porto4200-072PortoPortugal Department of Pathology Portuguese Oncology Institute of PortoPortoPortugal Department of Radiation Oncology Portuguese Oncology Institute of PortoPortoPortugal BIOGEM Molecular Biology and Genetics Research Institute83100AvellinoItaly IEOS Institute of Endocrinology and Oncology80100NaplesItaly

External beam radiotherapy(RT)is a leading first-line therapy for prostate cancer(PCa),and,in recent years,significant advances have been ***,RT resistance can arise and result in long-term recurrence or disease progression in the worst-case ***,making crucial the discovery of new targets for PCa ***,we generated a radioresistant PCa cell line,and found p53 to be highly expressed in radioresistant PCa cells,as well as in PCa patients with recurrent/disease progression submitted to *** dissection revealed that RT could promote p53 expression via epigenetic ***,a decrease of H3K27me3 occupancy at TP53 gene promoter,due to increased KDM6B activity,was observed in radioresistant PCa ***,p53 is essential for efficient DNA damage signaling response and cell recovery upon stress induction by prolonged fractionated ***,KDM6B inhibition by GSK-J4 significantly decreased p53 expression,consequently attenuating the radioresistant phenotype of PCa cells and hampering in vivo 3D tumor ***,this work contributes to improve the understanding of p53 as a mediator of signaling transduction in DNA damage repair,as well as the impact of epigenetic targeting for PCa radiosensitization.

关键词： TP53 damage cancer

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GaiaDoc： A Tool Focused on Business Requirements for Code Documentation with a CMMI Compliant and RUP Based on Requirement Flow

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通讯和计算机（中英文版） 2013年第5期10卷 593-602页

作者： Ferreira-Luz-junior Humberto Miranda-barros Rodolfo Department of Computer Science State University of Londrina Londrina 86051-990 Brazil

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Open abdomen in gastrointestinal surgery:Which technique is the best for temporary closure during damage control?

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World Journal of Gastrointestinal Surgery 2016年第8期8卷 590-597页

作者： Marcelo A F Ribeiro junior Emily Alves barros Sabrina Marques de Carvalho Vinicius Pereira Nascimento José Cruvinel Neto Alexandre Zanchenko Fonseca Department of Surgery University of Santo Amaro

AIM To compare the 3 main techniques of temporary closure of the abdominal cavity,vacuum assisted closure(vacuum-assisted closure therapy- VAC),Bogota bag and Barker technique,in damage control *** After systematic review of the literature,33 articles were selected to compare the efficiency of the three *** such as cost,infections,capacity of reconstruction of the abdominal wall,diseases associated with the technique,among others were *** The Bogota bag and Barker techniques present as advantage the availability of material and low cost,what is not observed in the VAC *** VAC technique is the most efficient,not only because it reduces the tension on the boarders of the lesion,but also removes stagnant fluids and debris and acts at cellular level increasing cell proliferation and *** bag presents the higher rates of skin laceration and evisceration,greater need for a stent for draining fluids and wash-ups,higher rates of intestinal adhesion to the abdominal *** Barker technique presents lack of efficiency in closing the abdominal wall and difficulty on maintaining pressure on the *** VAC dressing can generate irritation and dermatitis when the drape is applied,in addition to pain,infection and bleeding,as well as toxic shock syndrome,anaerobic sepsis and *** The VAC technique,showed to be superior allowing a better control of liquid on the third space,avoiding complications such as fistula with small mortality,low infection rate,and easier capability on primary closure of the abdominal cavity.

关键词： Trauma Damage control Abdominal compartment syndrome Temporary abdominal closure

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