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电力系统可视化技术(英文)

电力系统自动化 2005年第16期29卷 60-65页

作者： thomas j.overbye University of Illinois at Urbana-Champaign

介绍了可视化技术在电力系统潮流和最优潮流分析中应用的最新成果。讨论了应用动态变尺寸饼图和动画潮流箭头显示电力系统潮流;以及应用等高线显示母线电压和边际电价。此外,还讨论了交互式三维动画技术在电力系统可视化中的应用。所提... 详细信息

介绍了可视化技术在电力系统潮流和最优潮流分析中应用的最新成果。讨论了应用动态变尺寸饼图和动画潮流箭头显示电力系统潮流;以及应用等高线显示母线电压和边际电价。此外,还讨论了交互式三维动画技术在电力系统可视化中的应用。所提出的可视化技术不但可用于离线潮流和最优潮流分析,而且可用于电力系统控制中心在线潮流和最优潮流分析。

关键词：电力系统可视化等高线动画交互式三维技术

电力系统低频振荡模态和参与因子的可视化方法

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电网技术 2008年第10期32卷 74-78页

作者：王庆红 thomas j.overbye 广西电力工业勘察设计研究院广西壮族自治区南宁市530023 伊利诺斯大学香槟分校电气与计算机工程系美国厄巴纳及香槟市

对电力系统振荡研究而言,振荡模态和参与因子是最重要的2个信息,但在实际大系统中快速、准确地把握这2个关键信息是难点。文章研究了采用各种可视化手段展现振荡模态和参与因子的方法,使系统调度员能很快获取系统振荡的关键信息,确定引... 详细信息

对电力系统振荡研究而言,振荡模态和参与因子是最重要的2个信息,但在实际大系统中快速、准确地把握这2个关键信息是难点。文章研究了采用各种可视化手段展现振荡模态和参与因子的方法,使系统调度员能很快获取系统振荡的关键信息,确定引起系统振荡的关键机组并定量评估其影响。并以美国东南部200台发电机系统为例验证了上述方法的有效性。

关键词：电力系统模态参与因子可视化低频振荡

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电力系统振荡的可视化研究

电力系统振荡的可视化研究

中南七省（区）电力系统专业委员会第二十二届联合学术年会

作者：王庆红 thomas j.overbye 广西电力工业勘察设计研究院

过大的电力系统振荡会引起系统失稳。对系统振荡研究而言,振荡模式和参与因子是最重要的数据。但在大系统中,有成千上万的数据点。本文的目的就是形成和展示振荡模式形态和参与因子,这样就可以很快地获取重要信息。系统调度员或对系统... 详细信息

过大的电力系统振荡会引起系统失稳。对系统振荡研究而言,振荡模式和参与因子是最重要的数据。但在大系统中,有成千上万的数据点。本文的目的就是形成和展示振荡模式形态和参与因子,这样就可以很快地获取重要信息。系统调度员或对系统振荡有兴趣的人就可以很快地判断出哪些发电机引起了系统的振荡,并了解这些发电机各自对系统振荡的影响有多大。因为不同的用户偏好不同的信息可视化方法, 本文考虑了多种选择,包括改变颜色,大小和形状.两维和三维的显示方法都将得到论证。

关键词：振荡模式形态参与因子可视化

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电力系统振荡的可视化研究

南方电网技术 2007年第1期1卷 62-67页

作者：王庆红 thomas j.overbye 广西电力工业勘察设计研究院 Department of Electrical and Computer Engineering University of Illinoisat Urbana-Champaign Urbana IL61801

对系统振荡研究而言,振荡模式和参与因子是最重要的数据。本文研究形成和展示振荡模态和参与因子,以便系统调度员很快地获取重要信息,判断出引起系统的振荡是哪些发电机及其影响有多大。选择不同的信息可视化方法,包括改变颜色、大小和... 详细信息

对系统振荡研究而言,振荡模式和参与因子是最重要的数据。本文研究形成和展示振荡模态和参与因子,以便系统调度员很快地获取重要信息,判断出引起系统的振荡是哪些发电机及其影响有多大。选择不同的信息可视化方法,包括改变颜色、大小和形状,以及两维和三维的显示方法,满足不同的用户偏好。

关键词：振荡模态参与因子可视化

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可视化电力系统规划和实时应用统一平台

可视化电力系统规划和实时应用统一平台

Theory and classification of mass extinction causation

中国高等学校电力系统及其自动化专业第二十四届学术年会

作者：王庆红江兴月 Santiago Grijalva james Weber Caroline Marzinzik thomas j.overbye 广西电力工业勘察设计研究院 Powerword公司伊利诺斯大学香槟分校电气与计算机工程系

基于系统性能和安全因素的考虑,在上个世纪70年代初,电力系统规划和实时调度运行工具分别采用不同的模型、数据格式以及高级应用。这种状况一直持续到现在,给电力系统仿真和控制软件的开发应用及商业化带来了严峻的挑战。本文介绍了一... 详细信息

基于系统性能和安全因素的考虑,在上个世纪70年代初,电力系统规划和实时调度运行工具分别采用不同的模型、数据格式以及高级应用。这种状况一直持续到现在,给电力系统仿真和控制软件的开发应用及商业化带来了严峻的挑战。本文介绍了一种全新的拓扑处理方法,给出了一种电力规划软件架构,该架构能够无缝嵌入实时系统运行分析。采用该架构无需重新建立系统模型,也不需要改变现有规划软件或者EMS系统中已有的模型,更为重要的是不需要修改现有高级应用程序代码。该架构通过动态地创建全拓扑和简化网络拓扑来实现多个应用的集成。该架构及其程序已经在实际大型电力系统中通过测试应用。

关键词：拓扑处理 EMS系统电力系统规划实时应用

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National Science Review 2024年第1期11卷 16-36页

作者： thomas j.Algeo jun Shen State Key Laboratory of Biogeology and Environmental Geology China University of Geosciences—Wuhan State Key Laboratory of Geological Processes and Mineral Resources China University of Geosciences—Wuhan Department of Geosciences University of Cincinnati

Theory regarding the causation of mass extinctions is in need of systematization, which is the focus of this contribution. Every mass extinction has both an ultimate cause, i.e. the trigger that leads to various climato-environmental changes, and one or more proximate cause(s), i.e. the specific climato-environmental changes that result in elevated biotic mortality. With regard to ultimate causes, strong cases can be made that bolide(i.e. meteor) impacts, large igneous province(LIP) eruptions and bioevolutionary events have each triggered one or more of the Phanerozoic Big Five mass extinctions, and that tectono-oceanic changes have triggered some second-order extinction events. Apart from bolide impacts, other astronomical triggers(*** flares, gamma bursts and supernova explosions) remain entirely in the realm of speculation. With regard to proximate mechanisms, most extinctions are related to either carbon-release or carbon-burial processes, the former being associated with climatic warming, ocean acidification, reduced marine productivity and lower carbonate δ13C values, and the latter with climatic cooling, increased marine productivity and higher carbonate δ13C values. Environmental parameters such as marine redox conditions and terrestrial weathering intensity do not show consistent relationships with carbon-cycle *** this context, mass extinction causation can be usefully classified using a matrix of ultimate and proximate factors. Among the Big Five mass extinctions, the end-Cretaceous biocrisis is an example of a bolide-triggered carbon-release event, the end-Permian and end-Triassic biocrises are examples of LIP-triggered carbon-release events, and the Late Ordovician and Late Devonian biocrises are examples of bioevolution-triggered carbon-burial events. Whereas the bolide-impact and LIP-eruption mechanisms appear to invariably cause carbon release, bioevolutionary triggers can result in variable carbon-cycle changes, e.g. carbon burial durin

关键词： biocrisis ultimate cause proximate cause bolide large igneous province bioevolutionary event

EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors

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Signal Transduction and Targeted Therapy 2024年第2期9卷 679-692页

作者： Keith Al-Hasani Safiya Naina Marikar Harikrishnan Kaipananickal Scott Maxwell jun Okabe Ishant Khurana thomas Karagiannis julia j.Liang Lina Mariana thomas Loudovaris thomas Kay Assam El-Osta Epigenetics in Human Health and Disease Program Baker Heart and Diabetes Institute75 Commercial RoadMelbourne 3004 VICAustralia Department of Diabetes Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia Epigenetics in Human Health and Disease Laboratory Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia School of Science STEM CollegeRMIT UniversityMelbourne 3001 VICAustralia Immunology and Diabetes Unit St Vincent’s Institute of Medical ResearchFitzroy 3065 VICAustralia Department of Medicine and Therapeutics The Chinese University of Hong KongSha TinHong Kong SAR Hong Kong Institute of Diabetes and Obesity Prince of Wales HospitalThe Chinese University of Hong Kong3/F Lui Che Woo Clinical Sciences Building30-32-Ngan Shing StreetSha TinHong Kong SAR Li Ka Shing Institute of Health Sciences The Chinese University of Hong KongSha TinHong Kong SAR Biomedical Laboratory Science Department of TechnologyFaculty of HealthUniversity College CopenhagenCopenhagenDenmark

β-cells are a type of endocrine cell found in pancreatic islets that synthesize,store and release *** type 1 diabetes(T1D),T-cells of the immune system selectively destroy the insulin-producingβ-*** of these cells leads to a lifelong dependence on exogenous insulin administration for ***,there is an urgent need to identify novel therapies that stimulateβ-cell growth and induceβ-cell *** and others have shown that pancreatic ductal progenitor cells are a promising source for regeneratingβ-cells for T1D owing to their inherent differentiation *** transcriptional suppression is refractory to exocrine reaction and tightly controls the regenerative potential by the EZH2 *** the present study,we show that transient stimulation of exocrine cells,derived from juvenile and adult T1D donors to the FDAapproved EZH2 inhibitors GSK126 and Tazemetostat(Taz)influence a phenotypic shift towards aβ-like cell *** transition from repressed to permissive chromatin states are dependent on bivalent H3K27me3 and H3K4me3 chromatin *** EZH2 is fundamental toβ-cell regenerative *** pancreatic ductal cells exhibit insulin production and secretion in response to a physiological glucose challenge ex *** pre-clinical studies underscore the potential of small molecule inhibitors as novel modulators of ductal progenitor differentiation and a promising new approach for the restoration ofβ-like cell function.

关键词： EZH2 struction inhibitors

Examining the“revisability”benefit of hip resurfacing arthroplasty

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World journal of Orthopedics 2024年第6期15卷 554-559页

作者： jose George Adam j Taylor thomas P Schmalzried Department of Orthopedics Harbor UCLA Medical CenterTorranceCA 90509United States

BACKGROUND Hip resurfacing arthroplasty(HRA)is an alternative to total hip arthroplasty(THA)that is typically reserved for young active patients because it preserves ***,the benefits of HRA only hold true if conversion THA after failed HRA provides acceptable *** To compare patient reported outcomes for conversion THA after HRA failure to primary *** A retrospective review of 36 patients(37 hips)that underwent conversion THA for failed HRA between October 2006 and May 2019 by a single surgeon was *** reported outcomes[modified Harris Hip Score(mHHS),University of California Los Angeles(UCLA)activity score]were obtained via an email-based responder-anonymous *** were compared to normative data of a primary THA cohort with similar *** analysis was performed comparing outcomes of conversion THA for adverse local tissue reaction(ALTR)vs all other causes for *** The study group had a lower mHHS than the control group(81.7±13.8 vs 90.2±11.6,P<0.01);however,both groups had similar UCLA activity levels(7.5±2.3 vs 7.2±1.6,P=0.51).Patients that underwent conversion for non-ATLR causes had similar mHHS(85.2±11.5 vs 90.2±11.6,P=0.11)and higher UCLA activity levels(8.5±1.8 vs 7.2±1.6,P<0.01)compared to the control *** that underwent conversion for ATLR had worse mHHS(77.1±14.5 vs 90.2±11.6,P<0.01)and UCLA activity levels(6.1±2.3 vs 7.2±1.6,P=0.05)when compared to the control *** Patient outcomes equivalent to primary THA can be achieved following HRA conversion to ***,inferior outcomes were demonstrated for ALTR-related HRA *** selection and perhaps further studies examining alternative HRA bearing surfaces should be considered.

关键词： Total hip arthroplasty Hip resurfacing arthroplasty Conversion total hip arthroplasty Adverse local tissue reaction Patient reported outcome measures

Adeno-associated virus as a delivery vector for gene therapy of human diseases

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Signal Transduction and Targeted Therapy 2024年第5期9卷 1808-1840页

作者： jiang-Hui Wang Dominic j.Gessler Wei Zhan thomas L.Gallagher Guangping Gao Horae Gene Therapy Center University of Massachusetts Chan Medical SchoolWorcesterMA01605USA Department of Microbiology and Physiological Systems University of Massachusetts Chan Medical SchoolWorcesterMA01605USA Centre for Eye Research Australia Royal Victorian Eye and Ear HospitalEast MelbourneVIC3002Australia Ophthalmology Department of SurgeryUniversity of MelbourneEast MelbourneVIC3002Australia Department of Neurological Surgery University of Massachusetts Chan Medical SchoolWorcesterMA01605USA Department of Neurosurgery University of MinnesotaMinneapolisMN55455USA Department of Medicine University of Massachusetts Chan Medical SchoolWorcesterMA01605USA Li Weibo Institute for Rare Diseases Research University of Massachusetts Chan Medical SchoolWorcesterMA01605USA

Adeno-associated virus(AAV)has emerged as a pivotal delivery tool in clinical gene therapy owing to its minimal pathogenicity and ability to establish long-term gene expression in different *** AAV(rAAV)has been engineered for enhanced specificity and developed as a tool for treating various ***,as rAAV is being more widely used as a therapy,the increased demand has created challenges for the existing manufacturing *** rAAV-based gene therapy products have received regulatory approval,but there continue to be concerns about safely using high-dose viral therapies in humans,including immune responses and adverse effects such as genotoxicity,hepatotoxicity,thrombotic microangiopathy,and *** this review,we explore AAV biology with an emphasis on current vector engineering strategies and manufacturing *** discuss how rAAVs are being employed in ongoing clinical trials for ocular,neurological,metabolic,hematological,neuromuscular,and cardiovascular diseases as well as *** outline immune responses triggered by rAAV,address associated side effects,and discuss strategies to mitigate these *** hope that discussing recent advancements and current challenges in the field will be a helpful guide for researchers and clinicians navigating the ever-evolving landscape of rAAV-based gene therapy.

关键词： diseases specificity approval