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Incidence of urinary incontinence following endoscopic laser enucleation of the prostate by en-bloc and non-en-bloc techniques:a multicenter,real-world experience of 5068 patients

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Asian Journal of Andrology 2024年第3期26卷 233-238页

作者： Daniele Castellani Vineet Gauhar Khi Yung Fong Mario sofer Moisés Rodríguez socarrás Azimdjon N Tursunkulov Lie Kwok Ying sarvajit Biligere Ho Yee Tiong Dean Elterman Abhay Mahajan Mark Taratkin sorokin Nikolai Ivanovich Tanuj Pal Bhatia Dmitry Enikeev Nariman Gadzhiev Mohammed Taif Bendigeri Jeremy Yuen-Chun Teoh Marco Dellabella Fernando Gómez sancha Bhaskar Kumar somani thomas Reinhard William Herrmann Urology Unit IRCCS INRCAAncona 60127Italy Urology Unit Marche University HospitalLe Marche Polytechnic UniversityAncona 60126Italy Department of Urology Ng Teng Fong General HospitalSingapore 609606Singapore Yong Loo Lin school of Medicine National University of SingaporeSingapore 117597Singapore Department of Urology Tel Aviv Sourasky Medical CenterAffiliated to the Sackler School of MedicineTel Aviv UniversityTel Aviv 6423906Israel Department of Urology and Robotic surgery ICUA-Clínica CEMTROMadrid 28701Spain Urology Division Akfa Medline HospitalTashkent 100211Uzbekistan Advanced Urology Gleneagles HospitalSingapore 258499Singapore Department of Urology National University HospitalSingapore 119228Singapore Divisionof Urology Department of SurgeryUniversity of TorontoOntarioToronto M5G 2C4Canada Department of Urology Mahatma Gandhi Mission’s Medical College and HospitalAurangabad 431003India Institute for Urology and Reproductive Health Sechenov UniversityMoscow119435Russian Federation Department of Urologyand Andrology Lomonosov Moscow State UniversityMoscow 119992Russian Federation Department of Urology Sarvodaya Hospital and Research CentreFaridabadHaryana 121006India Department of Urology Medical University of ViennaVienna 1090Austria Department of Urology Saint-Petersburg State University HospitalSaint-Petersburg 199034Russian Federation Department of Urology Asian Institute of Nephrology and UrologyHyderabad 500082India s.H.Ho UrologyCentre Department of SurgeryFaculty of MedicineThe Chinese University of Hong KongHong Kong 96H2+Q9China Department of Urology University Hospitals Southampton NHS TrustSouthampton SO166YDUnited Kingdom Department of Urology Cantonal Hospital Thurgau AGFraunfeld 8500Switzerland

We aim to evaluate the incidence of incontinence following laser endoscopic enucleation of the prostate(EEP)comparing en-bloc(Group 1)versus 2-lobe/3-lobe techniques(Group 2).We performed a retrospective review of patients undergoing EEP for benign prostaticenlargement in 12 centers between January 2020 and January *** were presented as median and interquartile range(IQR).Univariable and multivariable logistic regression analysis was performed to evaluate factors associated with stress urinary incontinence(sUI)and mixed urinary incontinence(MUI).There were 1711 patients in Group 1 and 3357 patients in Group *** in Group 2were significantly younger(68[62–73]years vs 69[63–74]years,P=0.002).Median(interquartile range)prostate volume(PV)wassimilar between the groups(70[52–92]ml in Group 1 vs 70[54–90]ml in Group 2,P=0.774).There was no difference in preoperativeInternational Prostate symptom score,quality of life,or maximum flow ***,morcellation,and total surgical time weresignificantly shorter in Group *** 1 month,overall incontinence rate was 6.3%in Group 1 versus 5.3%in Group 2(P=0.12),and urge incontinence was significantly higher in Group 1(55.1%vs 37.3%in Group 2,Ps,the overall rate ofincontinence was 1.7%in Group 1 versus 2.3%in Group 2(P=0.06),and sUI was significantly higher in Group 2(55.6%vs 24.1%in Group 1,P=0.002).At multivariable analysis,PV and IPss were factors significantly associated with higher odds of transient sUI/***,surgical time,and no early apical release technique were factors associated with higher odds of persistent sUI/MUI.

关键词： benign prostatic hyperplasia en-bloc enucleation endoscopic enucleation of the prostate laser therapy stress urinaryincontinence urge urinary incontinence

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synthesis and characterization of a 1,3-dibutylimidazolium azide([BBIm][N_(3)]) : A promising green energetic ionic liquid

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Defence Technology（防务技术） 2024年第8期38卷 1-15页

作者： Nawel Matmat Amir Abdelaziz Djalal Trache Achour sabrina Ahmed Fouzi Tarchoun Hani Boukeciat sourbh Thakur Weiqiang Pang thomas M.Klapotke Energetic Materials Laboratory(EMLab) Teaching and Research Unit of Energetic ProcessesEcole Militaire PolytechniqueBP 17 Bordj El-BahriAlgiers 16046Algeria Department of Organic Chemistry Bioorganic Chemistry and BiotechnologySilesian University of TechnologyB.Krzywoustego 444-100 GliwicePoland Xi'an Modern Chemistry Research Institute Xi'an 710065China Energetic Materials Research Department of ChemistryLudwig-Maximilian UniversityMunich Butenandtstrasse 5-13(D)D-81377 MunichGermany

In the pursuit of advancing imidazolium-based energetic ionic liquids (EILs),the current study is devoted to the synthesis and characterization of 1,3-dibutyl-imidazolium azide ([BBIm][N_(3)]),as a novel member in this ionic liquids *** chemical structure of this EIL was rigorously characterized and confirmed using FTIR spectroscopy,1D,and 2D-NMR *** thermal behavior assessment was conducted through DsC and TGA *** analysis revealed an endothermic glass transition at T_(g)=-61℃,followed by an exothermic degradation event at T_(onset)=311℃.similarly,TGA thermograms exhibited a one-stage decomposition process resulting in 100% mass loss of the ***,the short-term thermal stability of the azide EIL was investigated by combining the non-isothermal TGA data with the TAs,it-KAs,and VYA/CE isoconversional kinetic ***,the Arrhenius parameters(E_(a)=154 kJ·mol^(-1),Log(A/s^(-1))=11.8) and the most probable reaction model g(a) were *** observed high decomposition temperatures and the significantly elevated activation energy affirm the enhanced thermal stability of the modified *** findings revealed that[BBIm][N_(3)]EIL can be a promising candidate for advanced energetic material application.

关键词： 1,3-dibutyl-imidazolium azide[BBIm][N_(3)] Energetic imidazolium-base ionic liquids 1D-/2D-NMR analyses short-term thermal stability Isoconversional approaches

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Comparison of trigeminal lateralization with differing stimulants

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World Journal of Otorhinolaryngology-Head and Neck surgery 2024年第1期10卷 66-69页

作者： Tiffany Chen Nicolas s.Poupore Michael C.shih thomas s.Edwards shaun A.Nguyen Zachary M.soler Rodney J.schlosser Department of Otolaryngology‐Head and Neck surgery Medical University of South CarolinaCharlestonSouth CarolinaUSA

Trigeminal-specific stimulants have been shown to activate different receptors preferentially and this likely accounts for variation in sensory *** is unclear whether trigeminal sensitivity is similar across different transient receptor potential(TRP)receptors or if dysfunction of different receptors results in differing patient ***,a prospective cohort study was conducted,consisting of trigeminal lateralization testing with three different stimulants(eucalyptol,isothiocyanate,acetic acid),olfaction testing with sniffin'sticks,and measurement of various patient‐reported outcome measures(PROMs).A total of 50 participants were enrolled across the olfactory *** TDI score was 27.1±8.3(range 7.0–39.5)with 38%normosmic and 62%*** trigeminal lateralization scores out of 20 in the overall cohort were 16.18(2.78)for eucalyptol,14.94(3.49)for mustard oil,and 15.28(3.68)for *** showed a significant correlation with threshold scores of sniffin'sticks.A significant correlation was found between acetic acid and various *** of the lateralization scores of the trigeminal stimulants correlated to each other significantly and there was no correlation to *** lack of correlation suggests that the measured sensitivity of one type of TRP receptor may not translate to similar sensitivity of the other *** investigations with TRPV1 and TRPA1 agonists are needed to corroborate our findings.

关键词： chemosensory olfaction trigeminal TRP receptor

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Thermomechanical Modelling of Industrial Vessels that Contain Refractory Masonry Linings

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China's Refractories 2024年第3期33卷 1-8页

作者： Alain GAssER Eric BLOND thomas sAYET Univ.Orléans Univ.ToursINSA-CVLLaMé(EA 7494)Orléans 45072France

some refractory linings that protect metallic vessels from the hot temperature of the products they contain are made of masonries with or without *** joints play an important role,reducing the stresses in the masonries during ***,the presence of these joints makes the behaviour of the masonry nonlinear and *** perform a thermomechanical simulation using a finite element method of an industrial vessel that contains hundreds or thousands of bricks and joints,microscopic models are not suitable due to the high computational time and the management of the behaviour of the joints(opening/closing)which affects the *** overcome these problems,it is proposed to replace the masonry by a homogeneous material that has a behaviour equivalent to the set of bricks and joints,using a periodic homogenization *** the joints can be closed or open,the equivalent material will have a different behaviour according to the joint ***,refractory materials have an elastic-viscoplastic behaviour at high ***,the equivalent material will have an orthotropic elastic-viscoplastic behaviour,requiring a nonlinear homogenisation *** overview of this approach developed at University of Orléans is presented with two industrial applications(blast-furnace and steel ladle).

关键词： thermomechanical simulation refractory masonry homogenization elastic-viscoplastic behaviour

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Eye on the sky: A UAP Research and Field study off New York’s Long Island Coast

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Open Journal of Applied sciences 2024年第8期14卷 2267-2295页

作者： John Joseph Tedesco Gerald thomas Tedesco Harvard Universitys Galileo Project Independent Research Affiliate Cambridge USA Consortium for The scientific Understanding of Natures Mysteries Holbrook USA Institute of Electrical and Electronic Engineers Washington USA American Academy of Environmental Engineers and scientist Annapolis USA Independent Researcher Holbrook USA

A ten-month field research study was meticulously conducted at Robert Moses state Park (RMsP) on the south shore of Long Island, NY. The objective was to determine if aerial phenomena of an unknown nature exist over a coastal location and to characterize their properties and behaviors. Primary and secondary field observation methods were utilized in this data-centric study. Forensic engineering principles and methodologies guided the study. The challenges set forward were object detection, observation, and characterization, where multispectral electro-optical devices and radar were employed due to limited visual acuity and intermittent presentation of the phenomena. The primary means of detection utilized a 3 cm X-band radar operating in two scan geometries, the X- and Y-axis. Multispectral electro-optical devices were utilized as a secondary means of detection and identification. Data was emphasized using HF and LF detectors and spectrum analyzers incorporating EM, ultrasonic, magnetic, and RF field transducers to record spectral data in these domains. Data collection concentrated on characterizing VIs, NIR, sWIR, LWIR, UVA, UVB, UVC, and the higher energy spectral range of ionizing radiation (alpha, beta, gamma, and X-ray) recorded by Geiger-Müller counters as well as special purpose semiconductor diode sensors.

关键词： Unidentified Anomalous Phenomenon (UAP) Forensic Techno-signatures Office of the Director of National Intelligence (ODNI) Multispectral Electro-Optical (MEO) Ultraviolet A Radiation (UVA) Ultraviolet B Radiation (UVB) Ultraviolet C Radiation (UVC) Visible (VIs) Near-Infrared (NIR) short-Wave Infrared (sWIR) Long-Wave Infrared (LWIR) Low-Frequency (LF) High-Frequency (HF) Radio-Frequency (RF) Alpha Beta Gamma Ultrasonic X-Band Active Radar Kinematics Aerodynamics Luminous spheroids Robert Moses state Park (RMsP)

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Modeling the Kinetics of Moisture Desorption from safou Pulp [Dacryodes edulis (G. Don) ***] before the Oil Extraction step

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Open Journal of Applied sciences 2024年第8期14卷 2050-2064页

作者： Anicet Frédéric Binaki Feueltgaldah Christian Bopoundza Bob Wilfrid Loumouamou Gueko séraphin Nguié Eliane Thérèse Biassala thomas silou Multidisciplinary Food and Nutrition Research Team Regional Center of Excellence in Food and Nutrition Faculty of Science and Technology Marien Ngouabi University Brazzaville Congo Process Engineering Laboratory UNESCO-ENSP Chair Marien Ngouabi University Brazzaville Congo CR2IE Chemistry and Technology Platform Higher School of Cataract Technology (EPrES) Brazzaville Congo

The aim of this work is to model the drying kinetics of safou pulp with or without endocarp using a phenomenological approach. Oven-drying kinetics at 70˚C, 90˚C and 105˚C were monitored using the curves given by the reduced mass as a function of time, which are modeled according to the Avrami/page, Fick and Peleg models using OringinPro 2018 software. The results showed that parameters k and n of the Avrami/Page model vary very little with fruit size and drying temperature (0.0018 ± 0.0002 k n k (Avrami model/page) were virtually identical, while b (Fick model) and n (Avrami model/page) were virtually identical for the same sample. For the Peleg model, the parameter a, varies from 0.0018 ± 0.0002 to 0.03328 ± 0.0079, with a ratio of 18.6 for all experimental conditions studied. However, with 0.977 R2 χ2 same applies to parameter b, which ranges from 0.82 ± 0.05 to 1.21 ± 0.02. Thus, drying modeling by these three models can be used to describe and predict the progress of oven-drying of safou pulp.

关键词： Drying Modeling Empirical Models Dacryodes edulis Congo Basin

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Fast and Balanced Charge Transport Enabled by solution-Processed Metal Oxide Layers for Efficient and stable Inverted Perovskite solar Cells

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Energy & Environmental Materials 2024年第2期7卷 240-248页

作者： Jing Zhang James Mcgettrick Kangyu Ji Jinxin Bi thomas Webb Xueping Liu Dongtao Liu Aobo Ren Yuren Xiang Bowei Li Vlad stolojan Trystan Watson samuel D.stranks Wei Zhang Advanced Technology Institute(ATI) University of SurreyGuildfordSurrey GU27XHUK sPECIFIC College of EngineeringSwansea UniversityBay Campus SA18ENSwansea UK Cavendish Laboratory University of CambridgeJ JThomson AvenueCambridge CB30HEUK Department of Chemical Engineering&Biotechnology University of CambridgePhilippa Fawcett DriveCambridge CB30ASUK

Metal oxide charge transport materials are preferable for realizing long-term stable and potentially low-cost perovskite solar cells(PsCs).However,due to some technical difficulties(e.g.,intricate fabrication protocols,high-temperature heating process,incompatible solvents,etc.),it is still challenging to achieve efficient and reliable all-metal-oxide-based ***,we developed efficient inverted PsCs(IPsCs)based on solution-processed nickel oxide(NiO_(x))and tin oxide(snO_(2))nanoparticles,working as hole and electron transport materials respectively,enabling a fast and balanced charge transfer for photogenerated charge *** further understanding and optimizing the perovskite/metal oxide interfaces,we have realized an outstanding power conversion efficiency(PCE)of 23.5%(the bandgap of the perovskite is 1.62 eV),which is the highest efficiency among IPsCs based on all-metal-oxide charge transport *** to these stable metal oxides and improved interface properties,ambient stability(retaining 95%of initial PCE after 1 month),thermal stability(retaining 80%of initial PCE after 2 weeks)and light stability(retaining 90%of initial PCE after 1000 hours aging)of resultant devices are enhanced *** addition,owing to the low-temperature fabrication procedures of the entire device,we have obtained a PCE of over 21%for flexible IPsCs with enhanced operational stability.

关键词： fast and balanced charge transfer inverted perovskite solar cells long-term stability low-temperature processing metal oxides

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Distortions in focusing laser pulses due to spatio-temporal couplings:an analytic description

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High Power Laser science and Engineering 2024年第3期12卷 20-40页

作者： Klaus steiniger Fabia Dietrich Daniel Albach Michael Bussmann Arie Irman Markus Loeser Richard Pausch thomas Püschel Roland sauerbrey susanne schöbel Ulrich schramm Mathias siebold Karl Zeil Alexander Debus Helmholtz-Zentrum Dresden-Rossendorf DresdenGermany CAsUs-Center for Advanced systems Understanding GörlitzGermany Technische Universität Dresden DresdenGermany

In ultra-short laser pulses,small changes in dispersion properties before the final focusing mirror can lead to severe pulse distortions around the focus and therefore to very different pulse properties at the point of laser±matter interaction,yielding unexpected interaction *** mapping between far-and near-field laser properties intricately depends on the spatial and angular dispersion properties as well as the focal *** a focused Gaussian laser pulse under the influence of angular,spatial and group-delay dispersion,we derive analytical expressions for its pulse-front tilt,duration and width from a fully analytic expression for its electric field in the time±space domain obtained with scalar diffraction *** expression is not only valid in and near the focus but also along the entire propagation distance from the focusing mirror to the *** relating angular,spatial and group-delay dispersion before focusing at an off-axis parabola,where they are well measurable,to the respective values in the pulse’s focus are obtained by a ray tracing ***,these formulas are used to show in example setups that the pulse-front tilts of lasers with small initial dispersion can become several tens of degrees larger in the vicinity of the focus while being small directly in the *** formulas derived here provide the analytical foundation for observations previously made in numerical *** numerically simulating Gaussian pulse propagation and measuring properties of the pulse at distances several Rayleigh lengths off the focus,we verify the analytic expressions.

关键词： group-delay dispersion pulse-front tilt spatio-temporal couplings third-order dispersion ultra-short laser pulses

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sMXL5 attenuates strigolactone signaling in Arabidopsis thaliana by inhibiting sMXL7 degradation

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Molecular Plant 2024年第4期17卷 631-647页

作者： Qingtian Li Haiyang Yu Wenwen Chang sunhyun Chang Michael Guzman Lionel Faure Eva-sophie Wallner Heqin Yan thomas Greb Lei Wang Ruifeng Yao David C.Nelson Department of Botany and Plant sciences University of CaliforniaRiversideRiversideCA 2521USA Yazhouwan National Laboratory Sanya 572025China Hainan seed Industry Laboratory Sanya 57205China state Key Laboratory of Chemo/Biosensing and Chemometrics Hunan Provincial Key Laboratory of Plant Functional Genomics and Developmental RegulationCollege of BiologyHunan UniversityChangsha 410082China Key Laboratory of seed Innovation Center for Agricultural Resources ResearchInstitute of Genetics and Developmental BiologyChinese Academy of SciencesShijiazhuangHebei 050021China University of Chinese Academy of sciences Beijing 10004China school of the sciences Biology DivisionTexas Woman’s UniversityDentonTX 76204USA Centre for Organismal studies(COs) Heidelberg University6120 HeidelbergGermany

Hormone-activated proteolysis is a recurring theme of plant hormone signaling *** strigolactone signaling,the enzyme receptor DWARF14(D14)and an F-box protein,MORE AXILLARY GROWTH2(MAX2),mark sUPPREssOR OF MAX21-LIKE(sMXL)family proteins sMXL6,sMXL7,and sMXL8 for rapid *** of these transcriptional corepressors initiates downstream growth *** homologous proteins sMXL3,sMXL4,and sMXL5,however,are resistant to MAX2-mediated *** discovered that the smxl4 smxl5 mutant has enhanced responses to ***5 attenuates strigolactone signaling by interfering with AtD14-sMXL7 ***5 interacts with AtD14 and sMXL7,providing two possible ways to inhibit sMXL7 ***5 function is partially dependent on an ethylene-responsive-element binding-factor-associated amphiphilic repression(EAR)motif,which typically mediates interactions with the TOPLEss family of transcriptional ***,we found that loss of the EAR motif reduces sMXL5-sMXL7 interactions and the attenuation of strigolactone signaling by *** hypothesize that integration of sMXL5 into heteromeric sMXL complexes reduces the susceptibility of sMXL6/7/8 proteins to strigolactone-activated degradation and that the EAR motif promotes the formation or stability of these *** mechanism may provide a way to spatially or temporally fine-tune strigolactone signaling through the regulation of sMXL5 expression or translation.

关键词： Arabidopsis typically inhibiting

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Utilization of RNA sequencing to investigate olfactory dysfunction in chronic rhinosinusitis without nasal polyps:A pilot study

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World Journal of Otorhinolaryngology-Head and Neck surgery 2024年第1期10卷 29-36页

作者： Jorge A.Gutierrez III Jeremy L.Barth Rodney J.schlosser thomas s.Edwards Timothy L.smith Zachary M.soler Department of Otolaryngology-Head and Neck surgery Medical University of South CarolinaCharlestonSouth CarolinaUSA Department of Regenerative Medicine&Cell Biology Medical University of South CarolinaCharlestonSouth CarolinaUSA Department of Otolaryngology-Head and Neck surgery Oregon Health&Science UniversityPortlandOregonUSA

Objectives:Prior research on olfactory dysfunction in chronic rhinosinusitis(CRs)has focused on patients with polyps and suggests that direct inflammation of the olfactory cleft mucosa plays a contributory *** purpose of this study was to evaluate gene expression in superior turbinate mucosal specimens,comparing normosmic and dysosmic CRs patients without polyps(CRssNP).Methods:Tissue samples were obtained from the superior turbinates of patients with CRssNP at the time of endoscopic sinus *** subsequently underwent RNA sequencing and functional analysis to investigate biological pathways associated with differentially expressed genes between dysosmic(n=7)and normosmic(n=4)***:Differential gene expression analysis comparing dysosmic and normosmic CRssNP patients showed upregulation of 563 genes and downregulation of 327 *** stringent criteria for multiple comparisons,one upregulated gene(Immediate Early Response 3[IER3])had an false discovery rate(FDR)correction adjustedP value considered statistically significant(Psis revealed eight biological pathways significantly different between dysosmic and normosmic patients(Psignaling,IL-10 signaling,and rhodopsin-like ***:RNA sequencing of the superior turbinates in patients with CRssNP can provide valuable information regarding biological pathways and genes involved in olfactory *** study supports literature suggesting that Type 2 inflammation may play a role in olfactory dysfunction in at least some patients with *** study also prompts questions regarding the role of IL-10,rhodopsin-like receptors,andIER3 in the pathogenesis of olfactory dysfunction.

关键词： chronic rhinosinusitis without nasal polyps olfactory dysfunction RNA sequencing

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