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Neural Regeneration Research 2021年第9期16卷 1779-1780页

作者： thomas A.ryan David A.Tumbarello Institute of Systems Molecular&Integrative BiologyFaculty of Health&Life SciencesNuffield WingSherrington BuildingUniversity of LiverpoolLiverpoolUK Biological Sciences Life Science Building 85University of SouthamptonHighfield CampusSouthamptonUK

Mitochondria are well known for their function in energy production;however they also play a crucial role in phospholipid transfer, inflammation, calcium balance and cell death, positioning them as a central regulator of cellular homeostasis. The cell therefore relies on quality control mechanisms to limit mitochondrial damage and the production of harmful reactive oxygen species(ROS).

关键词： homeostasis damage limit

Metabolic syndrome and the urinary microbiome of patients undergoing percutaneous nephrolithotomy

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Asian Journal of Urology 2024年第2期11卷 316-323页

作者： ryan A.Dornbier Chirag P.Doshi Shalin C.Desai Petar Bajic Michelle Van Kuiken Mark Khemmani Ahmer V.Farooq Larissa Bresler thomas M.T.Turk Alan J.Wolfe Kristin G.Baldea Loyola University Medical Center Department of UrologyMaywoodILUSA Loyola University Chicago Department of Microbiology and ImmunologyMaywoodILUSA

Objective:To identify possible stone-promoting microbes,we compared the profiles of microbes grown from stones of patients with and without metabolic syndrome(MetS).The association between MetS and urinary stone disease is well established,but the exact pathophysiologic relationship remains *** evidence suggests urinary tract dysbiosis may lead to increased nephrolithiasis ***:At the time of percutaneous nephrolithotomy,bladder urine and stone fragments were collected from patients with and without *** sample types were subjected to expanded quantitative urine culture(EQUC)and 16 S ribosomal RNA gene ***:Fifty-seven patients included 12 controls(21.1%)and 45 MetS patients(78.9%).Both cohorts were similar with respect to demographics and non-MetS *** controls had uric acid stone *** EQUC,bacteria were detected more frequently in MetS stones(42.2%)compared to controls(8.3%)(p=0.041).Bacteria also were more abundant in stones of MetS patients compared to *** validate our EQUC results,we performed 16 S ribosomal RNA gene *** 12/16(75.0%)sequence-positive stones,EQUC reliably isolated at least one species of the sequenced *** were detected in both“infectious”and“non-infectious”stone ***:Bacteria are more common and more abundant in MetS stones than control *** findings support a role for bacteria in urinary stone disease for patients with MetS regardless of stone composition.

关键词： Nephrolithiasis Urolithiasis Metabolic syndrome Urinary microbiome Percutaneous nephrolithotomy

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丰富SharePointn搜索结果

Windows IT Pro Magazine（国际中文版） 2009年第12期 49-51页

作者： ryan thomas 孙健(译)

你可能不需要企业信息架构的庞大课程或者改造已有的SharePoint环境的宏伟计划。你只需要一些技巧和免费的或不太责的工具来帮助提高数据的结构和目录。

关键词：搜索结果 SharePoint 企业信息架构目录宏

SharePoint工作流——无需编写代码即可改进业务流程

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Windows IT Pro Magazine（国际中文版） 2009年第5期 44-47,50页

作者： ryan thomas 高朝勤(译)

Microsoft Office Share Point Server（MOSS）2007包含了多种开箱即用的工作流。组织可以利用这些SharePoint工作流创建功能强大的业务流程，这些业务流程可以帮助组织节约资金，并使组织更易于管理、更有效率、更具遵从性。

关键词： SharePoint 业务流程工作流 Microsoft 代码编写 Office 节约资金

漫步InfoPath 2010和SharePoint 2010

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Windows IT Pro Magazine（国际中文版） 2010年第9期 63-66页

作者： ryan thomas 黄永兵(译者) Syrinx顾问咨询公司不详

InfoPath是一款功能丰富的数据收集工具，旨在SharePoint中简单、高效地创建表单。实现开箱即用或定制工作流的目标，然而。对于IT专业人员。甚至是SharePoint开发人员而言，InfoPath仍然是一个神秘的应用程序。本文就将向你展示如何在S... 详细信息

InfoPath是一款功能丰富的数据收集工具，旨在SharePoint中简单、高效地创建表单。实现开箱即用或定制工作流的目标，然而。对于IT专业人员。甚至是SharePoint开发人员而言，InfoPath仍然是一个神秘的应用程序。本文就将向你展示如何在SharePoint环境中集成InfoPath表单。并且无需编写一行代码。

关键词： SharePoint InfoPath 数据收集 IT专业应用程序工作流表单定制

Helicobacter pylori:High dose amoxicillin does not improve primary or secondary eradication rates in an Irish cohort

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World Journal of Clinical Cases 2024年第16期12卷 2773-2779页

作者： Conor Costigan Aoife M O'Sullivan Jim O'Connell Shreyashee Sengupta thomas Butler Stephen Molloy Fintan John O'Hara Barbara ryan Niall Breslin Sarah O'Donnell Anthony O'Connor Sinead Smith Deirdre McNamara Trinity Academic Gastroenterology Group School of Medicine-Trinity College DublinDublin D2Ireland Department of Gastroenterology Tallaght University HospitalDublin D24 NR0AIreland

BACKGROUND Helicobacter pylori(***)eradication rates have fallen globally,likely in large part due to increasing antibiotic resistance to traditional *** areas of high clarithromycin and metronidazole resistance such as ours,Maastricht VI guidelines suggest high dose amoxicillin dual therapy(HDADT)can be considered,subject to evidence for local *** this study we assess efficacy of HDADT therapy for *** eradication in an Irish *** To assess the efficacy of HDADT therapy for *** eradication in an Irish cohort as both first line,and subsequent therapy for patients diagnosed with *** All patients testing positive for *** in a tertiary centre were treated prospectively with HDADT(amoxicillin 1 g tid and esomeprazole 40 mg bid×14 d)over a period of 8 *** was confirmed with Urea Breath Test at least 4 wk after cessation of therapy.A delta-over-baseline>4%was considered *** demographics and treatment outcomes were recorded,analysed and controlled for basic demographics and prior *** *** One hundred and ninety-eight patients were identified with *** infection,10 patients were excluded due to penicillin allergy and 38 patients refused follow up *** all 139 were included in the analysis,55%(n=76)were female,mean age was 46.6 ***,93(67%)of patients were treatment-naïve and 46(33%)had received at least one previous course of *** groups were statistically ***-reported compliance with HDADT was 97%,mild side-effects occurred in 7%.There were no serious adverse drug *** the eradication rate for our cohort was 56%(78/139).Eradication rates were worse for those with previous treatment[43%(20/46)vs 62%(58/93),P=0.0458,odds ratio=2.15].Age and Gender had no effect on eradication *** Overall eradication rates with HDADT were *** being a simple and possibly better tolerated regime,these results do not

关键词： Helicobacter pylori eradication Helicobacter pylori High dose amoxicillin High dose amoxicillin dual therapy Triple therapy

Real-time temperature prediction of electric machines using machine learning with physically informed features

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Energy and AI 2023年第4期14卷 415-425页

作者： ryan Hughes thomas Haidinger Xiaoze Pei Christopher Vagg University of Bath UK AVL List GmbH Austria

Accurate estimation of the internal temperatures of electric machines is critical to increasing their power density and reliability since key temperatures,such as magnet temperature,are often difficult to *** work presents a new machine learning based modelling approach,incorporating novel physically informed feature engineering,which achieves best-in-class accuracy and reduced training *** different features introduced are proportional to sources of machine losses and require no prior knowledge of the machine,hence the models are completely data *** using a standard experimental dataset shows that modelling errors can be reduced by up to 82.5%,resulting in the lowest mean squared error recorded in the literature of 2.40 K^(2).Additionally,models can be trained with less training data and have lower sensitivity to data ***-ically,it was possible to train a loss enhanced multilayer perceptron model to a mean squared error<5 K^(2) with 90 h of training data,and an enhanced ordinary least squares model with just 60 h to the same *** inference time of the model can be 1–2 orders of magnitude faster than competing models and requires no time to optimise hyperparameters,compared to weeks or months for other state-of-the-art prediction *** results are highly important for enabling low-cost real-time temperature monitoring of electric machines to improve operational efficiency,safety,reliability,and power density.

关键词： Thermal model Real-time Electric machine Machine learning Losses

RFID的未来之路大有希望——众多美国专家谈RFID

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金卡工程 2006年第4期10卷 52-56页

作者：本刊编辑部 Kevin Ashton Erik Michielsen Rafael Moreno Shahram Moradpour Chantal Polsonetti thomas ryan Louis Sirico 麻省理工学院Auto-ID中心 ABI研究公司波多黎各Cesar Castillo公司 Cleritec Systems公司 ARC咨询集团 TKR联合咨询公司

根据有关的市场预测报告，RFID（无线射频识别）的未来之路是大有希望的。据IDTechEx公司提供的最新报告估计：2006年，RFID标签的销售量几乎将达到自其被发明以来60年内的总销售量的三倍之多；全球RFID市场额到2008年将达到70亿美元。... 详细信息

根据有关的市场预测报告，RFID（无线射频识别）的未来之路是大有希望的。据IDTechEx公司提供的最新报告估计：2006年，RFID标签的销售量几乎将达到自其被发明以来60年内的总销售量的三倍之多；全球RFID市场额到2008年将达到70亿美元。这主要是因为单个产品级别RFID的发展速度比人们预想的要快得多，另外它们比货盘或包装箱级别的RFID标签所面临的挑战也要少。

关键词： RFID标签美国专家市场预测报告无线射频识别销售量速度比包装箱公司美元

Unmet supportive care needs in families of children with chronic health conditions: an Australian cross‑sectional study

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World Journal of Pediatrics 2023年第12期19卷 1181-1191页

作者： Sangeetha thomas Linda K.Byrne Nicholas P.ryan Christel Hendrieckx Victoria White School of Psychology Faculty of HealthDeakin UniversityMelbourneVIC 3125Australia Department of Paediatrics University of MelbourneMelbourneVICAustralia Australian Centre for Behavioural Research in Diabetes MelbourneVICAustralia Institute of Health Transformation Deakin UniversityMelbourneVICAustralia Cancer Council Victoria MelbourneVICAustralia

Background The aim of this study was to identify similarities and diferences in the unmet supportive care needs(USCN)of families of children with major chronic health conditions(CHCs)using a universal need assessment *** A cross-sectional online survey involving parents of children with congenital heart disease(CHD),type 1 diabetes mellitus(T1D),cancer,and asthma diagnosed within the last 5 years recruited via social media and support ***-four items assessing the USCN across six domains(care needs,physical and social needs,informational needs,support needs,fnancial needs,child-related emotional needs)were responded to on a 4-point Likert scale[no need(1)to high need(4)].Descriptive statistics identifed the level of need,and linear regressions identifed factors associated with higher need domain *** to small numbers,the asthma group was excluded from comparisons across *** One hundred and ninety-four parents completed the survey(CHD:n=97,T1D:n=50,cancer:n=39,and asthma:n=8).Parents of children with cancer were most likely to report at least one USCN(92%),followed by parents of children with T1D(62%).The fve most commonly reported USCN across CHCs were drawn from four domains:child-related emotional,support,care,and *** need items were included in the top fve needs for all conditions.A higher USCN was associated with a greater frequency of hospital visits and the absence of parental *** Using a universal need assessment tool,this is one of the frst studies to characterize USCN in families of children diagnosed with common *** proportions endorsing diferent needs varied across conditions,the most endorsed needs were similar across the illness *** suggests that support programs or services could be shared across diferent CHCs.

关键词： Children Chronic illness Need assessment Unmet supportive care needs

应用运动超声心动图发现静息时左室壁运动正常患者的冠心病

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心肺血管病杂志 1989年第2期 128-128页

作者： thomas ryan ,刘晓惠

很多学者研究了运动超声心动图在诊断冠心病方面的应用。本文作者对静息状态时左室壁运动正常的64名患者,在冠脉造影之前进行平板运动超声心动图负荷试验检查,发现冠脉造影显示正常的24名患者运动超声心动图结果均为正常(特异性100%),... 详细信息

很多学者研究了运动超声心动图在诊断冠心病方面的应用。本文作者对静息状态时左室壁运动正常的64名患者,在冠脉造影之前进行平板运动超声心动图负荷试验检查,发现冠脉造影显示正常的24名患者运动超声心动图结果均为正常(特异性100%),冠状动脉狭窄≥50%的40名冠心病患者,其中9人为正常的运动超声心动图(敏感性78%),6人为单支血管病变。对单支血管病变的25人,运动超声心动图诊断的敏感性要比单纯平板运动试验要高(76与36%,P=0.01),在多

关键词：运动正常左室壁冠心病冠状动脉病超声心动图超声波诊断患者