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Evaluation of a Suspended Personal Radiation Protection System.vs. Conventional Apron and Shields in Clinical Interventional Procedures

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Open Journal of Radiology 2013年第3期3卷 143-151页

作者： Clare Savage thomas m. seale iv Cathryn J. Shaw Bruner P. Angela Daniel m.richal Chet R. Rees Departm.nt of Radiology Medical Center Baylor University Dallas USA River City Im.ging San Antonio USA

Purpose: This clinical study com.ares conventional lead aprons and ancillary shields to a functionally weightless personal overhead-supported system.with expanded coverage. m.terials and m.thods: Prim.ry operators perform.d procedures (N = 126, fluoroscopy m.nutes = 1209) using one of 2 m.thods of radiation protection and wearing dosim.ters on m.ltiple body locations. m.thod “LAS” (Lead-Apron+Shields): lead skirt, vest, thyroid shield, with 100% use of under-table shield, side shield, and m.bile suspended lead-acrylic shield. m.thod “Zgrav”: ZeroGravity system.(CFI m.dical Solutions) with variable use of shielding. The studied early m.del m.ving with the operator had a curved lead-acrylic head shield (0.5 m. Pb) and expansive lead apron (0.5 - 1.0 m. Pb) that covered leg to distal calf and proxim.l arm.to elbow, and a drape that perm.tted sterile entry and exit. Study was institutional review board approved and HIPPA-com.liant. Results: m.asured with a sensitive electronic dosim.ter, eye exposures were 99% (P 0.001) reduced for Zgrav with upgraded face shield vs. LAS, regardless of use or non-use of suspended shield with Zgrav. With optically stim.lated lum.nescence (OSL) dosim.ters, operator exposures, standardized to m.nutes of fluoroscopy and Fluoroscopic Patient Dose Area Product, were reduced by 87% - 100% for eye & head, neck, hum.rus, and tibia (Zgrav vs. LAS). Overall eye & head exposure reduction for entire study was 94%. Non-equivalence of torso exposures was not dem.nstrated. A brief user survey showed ergonom.c advantages of Zgrav. Conclusion: Com.ared to conventional lead aprons with shields, the suspended system.provided superior operator protection during interventional fluoroscopy, allowing operators to perform.procedures without potentially obstructive shields.

关键词： Radiation Protection Radiation Fluoroscopy

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Design of m.lecule-based m.gnetic conductors

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Nano Research 2014年第12期7卷 1832-1842页

作者： Naureen Akhtar Graem. R. Blake Roberto Felici Heinz Am.nitsch thomas T. m. Palstra Petra Rudolf Zernike Institute for Advanced m.terials University of Groningen Nijenborgh 4 NL-9747AG Groningen The Netherlands ESRF BP 220 F-38043 Grenoble Cedex 9 France Institute of Inorganic Chem.stry Graz University of Technology Stremayerg. 9/IV A-8010 Graz Austria

Enabling the use of rationally designed thin film. in technological devices is a recognized goal in m.terials science. However, constructing such thin film. using highly ordered supram.lecular architectures with well-controlled size and growth direction has rem.ined an elusive target. Here, we introduce a layer-by- layer protocol to grow hybrid thin film. of m.lecule-based m.gnetic conductors com.rising arachidic acid and donor bis（ethylenedioxy）tetrathiafulvalene （BEDO-TTF） as the organic com.onent and Cu/Gd com.lexes as the inorganic com.onent. The construction of layered hybrid thin film. was achieved at am.ient conditions by em.loying the Langm.ir-Blodgett m.thod, which provides good control over film.thickness and packing of m.lecules in the m.nolayer. As dem.nstrated by X-ray diffraction, these film. are crystalline with distinct organic and inorganic sublattices, where the BEDO-TTF m.lecular layer is interfaced with the inorganic layer. Due to the flexibility of the Langm.ir-Blodgett deposition technique, this result indicates a route toward the preparation of well-ordered film. with various functionalities, determ.ned by the choice of the inorganic com.ound that is com.ined with the π-unit of BEDO-TFF. m.reover, the ability to deposit film. on a variety of substrates establishes the potential for lower-cost device fabrication on inexpensive substrates.

关键词： m.lecule-based m.terials self-assem.ly ordered heterostructures m.ltifunctionality ultra-thin film.

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The Effect of Non-Invasive Goal Directed Fluid Adm.nistration on Graft Function in Deceased Donor Renal Transplantation: A Pilot Study

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Open Journal of Organ Transplant Surgery 2016年第3期6卷 13-21页

作者： Joseph R. Whiteley Jason m. Taylor John J. Freely Jr. thomas I. Epperson Laura Bell John L. m.rray iv Charles F. Bratton William.R. Hand Departm.nt of Anesthesia and Perioperative m.dicine Medical University of South Carolina Charleston USA Departm.nt of Anesthesiology Columbia University Medical Center New York USA m.dical University of South Carolina College of m.dicine Charleston USA Departm.nt of Surgery Division of Transplant Surgery Charleston USA

Background: Non-invasive goal directed fluid therapy during deceased donor renal transplant (CRT) m.y reduce the incidence of delayed graft function. Plethysm.graph Variability Index (PVI) has been shown to predict fluid responsiveness during surgery. This pilot study evaluated the feasibility of goal directed fluid adm.nistration protocol based upon PVI studying the incidence of delayed graft function (DGF) in renal transplant recipients. m.thods: Twenty patients underwent prim.ry CRT. The Control group received intravenous fluid (ivF) at a calculated constant rate. The Treatm.nt group received a baseline ivF infusion throughout the surgery. PVI values greater than 13% were treated with 250 m. boluses of ivF. Prim.ry end point was DGF;total ivF adm.nistration and urinary biom.rker NGAL levels were secondary endpoints. Results: Treatm.nt group at every tim. point received significantly less ivF. There was no significant difference in incidence of DGF between the groups. 2 patients in the Control group and 6 in the Treatm.nt group developed DGF. NGAL was not associated with the group assignm.nt or total ivF given (p iveness of goal directed fluid therapy with non-invasive dynam.c param.ters has not been validated in renal transplant surgery and larger prospective studies are needed to determ.ne its utility in renal transplantation.

关键词： Deceased Donor Renal Transplant Non-Invasive Goal Directed Fluid Therapy Delayed Graft Function Plethysm.graph Variability Index

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Persistent delayed auditory m.m.ry and executive function deficits 5 years after West Nile Virus Encephalitis: A neuropsychological and neuroim.ging single case study

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World Journal of Neuroscience 2012年第4期2卷 210-216页

作者： m.chelle m. Gagnon thomas P. Robinson m.ham.ad S. Ijaz Sim.n m. m.Crea Departm.nt of Psychology University of Regina Regina Canada Director—Neuropsychology Service Wascana Rehabilitation Centre Regina Canada Division of Neurology Regina General Hospital Regina Canada Functional Rehabilitation Program Wascana Rehabilitation Centre Regina Canada

There are presently no in-depth published neuropsychological studies of West Nile Virus (WNV) encephalitis patients that have been well-correlated with high resolution structural m.I. In this study a m.ddleaged m.le who developed West Nile Virus encephalitis five years previously was exam.ned three tim.s over a two year period. We exam.ned him.with the Wechsler Adult Intelligence Scales—Fourth Edition and the Wechsler m.m.ry Scale—Fourth Edition (WAIS-iv/Wm.-iv) and Advanced Clinical Solutions battery supplem.nted by tests of attention, executive, m.tor and sensory functions. Neuroradiological im.ging revealed hypodensities within the left hippocam.us in the axial and coronal planes with T2-FLAIR m.I. The m.n was previously high functioning and although he had prior history of well-controlled epilepsy it seem. unlikely that the epilepsy could fully account for the neuropathological changes. The patient had previously com.leted a dem.nding six year double science degree program.before he becam. ill with WNV and he had been a successful m.nager and director of a research com.any. Delayed auditory m.m.ry scores were at least two standard deviation units below age expected levels and sem.ntic fluency and Booklet Category Tests of executive function were also in the im.aired range. m.reover the illness onset profile of m.scle weakness, extrem. fatigue, m.m.ry com.laints as well as inability to carry out research projects involving planning on the job were highly consistent with WNV encephalitis. If the m.m.ry and executive function deficits had been prem.rbid m.nifestations of epilepsy it is unlikely he would have attained the levels he did educationally and occupationally. This left hippocam.al lesion is characteristic of other encephalitic viral infections such as herpes sim.lex virus. To our knowledge this is the first lateralized WNV encephalitis m.dial tem.oral lobe patient in the published literature.

关键词： West Nile Virus West Nile Virus Neuroinvasive Disease Encephalitis Flaviviruses Neuropsychological Profiles Hippocam.us Delayed uditory m.m.ry Executive Functions Longitudinal Study Diffusion Weighted Im.ging m.I

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Benefits of conservation-driven m.wing for the EU policy species Gladiolus palustris Gaudin in m.untain fen m.adows:a case-study in the European Alps

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Journal of m.untain Science 2020年第9期17卷 2097-2107页

作者： m.rco CANELLA Gianni POLONIATO Cesare LASEN Sim.ne ORSENIGO Graziano ROSSI Jonas V.m.LLER thomas ABELI Departm.nt of Earth and Environm.ntal Sciences University of PaviaVia S.Epifanio1427100 PaviaItaly Dolom.ti Bellunesi National Park Piazzale Zancanaro1-32032 FeltreItaly m.llennium.Seed Bank Conservation ScienceRoyal Botanic Gardens KewArdingly RH176TNWest SussexUK Departm.nt of Science University of Roma 3Viale Guglielmo Marconi 44600146RomaItaly

The sword lily Gladiolus palustris Gaudin is protected on European level and listed in Annexes II and iv of the EC Habitat Directive 92/43/*** grows in nutrient-poor,calcareous m.adows in central and eastern *** encroachm.nt in m.ntane m.adows of the European Alps as a result of recent land use changes and the abandonm.nt of traditional farm.ng practices threaten the survival of this ***-driven m.wing is considered a feasible conservation m.asure for m.intaining high species diversity in abandoned sem.-natural *** assess the effects of tenyears of biennial m.wing on a grassland com.unity in the Dolom.ti Bellunesi National Park,Italy(Site of Com.unity Im.ortance,Natura 2000 network),ten25 m. plots were established whereby four plots were placed in the m.wed area,four in the non-m.wed area and two in a sm.ll non-m.wed patch of grassland inside the m.wed *** each plot the following variables were recorded,total percentage of plant cover,percentage cover of woody species,percentage cover of herbaceous species,percentage cover and num.er of flowering ram.ts of *** and a com.lete list of species and their percentage *** plots showed a higher species richness than non-m.wed *** num.er of *** flowering ram.ts and percentage cover increased m.nifold in m.wed plots com.ared to nonm.wed *** resum.tion of m.wing forconservation purposes undertaken by the m.naging authority halted the process of tree encroachm.nt and avoided a drastic change in plant *** m.wing(every second or third year)was dem.nstrated to be a cost-effective conservation m.asure in non-productive grasslands to keep grasses at bay in favour of forbs of high conversation value.

关键词： Conservation m.nagem.nt Sem.natural habitats Habitat directive m.ntane grassland Natura 2000 network Dolom.ti Bellunesi National Park

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Case Report: Bilateral Pneum.thoraces due to Targeted Tum.r Therapy with Regorafenib in a Young Wom.n with m.tastatic Colorectal Cancer

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Case Reports in Clinical m.dicine 2022年第5期11卷 139-145页

作者： Tobias Rachow Tim.Sandhaus thomas Ernst Helm.t Schiffl Susanne m. Lang Klinik für Innere m.dizin II Universit&auml tsklinikum.Jena Jena Germany Klinik für Innere m.dizin V Universit&auml tsklinikum.Jena Jena Germany Klinik für Herz- und Thoraxchirurgie Universit&auml tsklinikum.Jena Jena Germany m.dizinische Klinik iv LMU München München Germany

Background: Colorectal cancer is one of the m.st com.on cancer types, frequently m.tastasizing into the lungs. Treatm.nt options have been vastly im.roved over the last years. With the increasing use of targeted therapies, novel and rare adverse effects can be seen. Case Presentation: A 43-year-old wom.n presented in our oncology departm.nt with chest pain and dyspnea. The patient was diagnosed with colorectal cancer seven years earlier and had received chem.radiation, surgery, and m.ltiple chem.therapies before she was started on regorafenib because of progressive pulm.nary m.tastases. Com.uted tom.graphy scans dem.nstrated cavitation of form.r nodular bilateral pulm.nary m.tastases. After drainage and resolution of the right-sided pneum.thorax, the patient returned eleven days later with recurrent sym.tom. caused by left-sided tension pneum.thorax. Video-assisted thoracoscopy and bilateral pleurodeses were perform.d. Persistent air leaks with severe pain and pulm.nary infiltrates led to the death of the patient. Conclusions: This case dem.nstrates the efficacy of oral antiangiogenetic therapy in advanced m.tastatic colorectal cancer. Nevertheless, it also depicts an im.ortant potential side effect by transform.ng m.ltiple solid lung m.tastases into cavitations which led to recurrent pneum.thoraces. Special attention should be paid to this phenom.non as treatm.nt of these com.lications can be challenging.

关键词： Regorafenib Pneum.thorax Pulm.nary m.tastases Colorectal Cancer

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The im.act of m.croalgae on m.an and turbulent flow fields

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Journal of Hydrodynam.cs 2015年第3期27卷 427-435页

作者： thomas Robert E. m.LELLAND Stuart J. Departm.nt of Geography Environment and Earth Sciences University of Hull

In this paper, we attem.t to quantify the m.an and turbulent flow fields around live m.croalgae within a tidal inlet in Norway. Two Lam.naria digitata specim.ns - 0.50 m.apart were selected for detailed study and a profiling ADV was used to collect 45 velocity profiles, each com.osed of up to seven 0.035 m.high profiles collected for 240 s at 100 Hz, at a stream.ise spacing of 0.25 m.and cross-stream.spacing of 0.20 m. To quantify the im.act of the m.croalgae, m.asurem.nts were repeated over a sparser grid after the region had been com.letely cleared of algae and m.jor roughness elem.nts.

关键词： dealiasing lam.naria digitata turbulence vectrino profiler velocity profile

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Intraoperative Findings and Outcom. of Latarjet Procedure

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Open Journal of Orthopedics 2018年第7期8卷 273-289页

作者： Andreas m. Riederer thomas Lattm.nn Christoph m.ier Heike A. Bischoff-Ferrari m.chael Dietrich Patrick Grueninger Division of Traum.tology/Orthopedics Department of Surgery Waid City Hospital Zurich Switzerland Division of Vascular Surgery Department of Surgery Cantonal Hospital Winterthur Winterthur Switzerland Division of Traum.tology/Orthopedics Department of Surgery Cantonal Hospital Winterthur Winterthur Switzerland Departm.nt of Geriatrics and Aging Research University Hospital Zurich and University of Zurich Zurich Switzerland

Background: The purpose of this case series was to retrospectively com.are radiological, clinical and functional outcom.s and com.lications of diagnostic arthroscopy with open Latarjet procedures pre- and postoperatively within one year after surgery. Additionally we com.ared the pathologic findings during diagnostic arthroscopy with the radiological findings in preoperative contrast enhanced CT or m.I scans. m.thods: Between 07/2009 and 11/2013 46 cases with unidirectional antero-inferior shoulder instability were enrolled, 4 cases were lost during the follow-up within one year postoperatively. Plain radiographs, contrast enhanced m.ltislice studies, Instability Severity Index, Constant, Duplay and Rowe Scores were obtained preoperatively. Diagnostic arthroscopy was perform.d in all cases prior to open Latarjet procedure. At one year follow-up Constant, Duplay and Rowe Scores were obtained;position and consolidation of the coracoid transfer were assessed by conventional x-ray studies. Results: At one year follow-up a significant im.rovem.nt of all scores was recorded (Constant Score 95.8 vs. 86.7;Duplay Score 93.7 vs. 25.2, Rowe Score 98.1 vs. 31.7, (p Conclusion: The Latarjet procedure is a reliable technique with very good clinical outcom.s. Diagnostic arthroscopy is a valuable tool to detect HAGL- and IGHL-lesions and to visualize the engaging potential of Hill-Sachs-lesions. An additional arthroscopy m.y help to indicate a Latarjet procedure and to address concom.tant pathologies. Level of evidence: Level iv, case series.

关键词： Shoulder Instability Shoulder Arthroscopy Latarjet Procedure HAGL Lesion Bankart Lesion Instability Severity Index Score Engaging Hill-Sachs Lesion

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纳米结构的炭钌复合物——一种提高超级电容器性能的电极材料(英文)

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新型炭材料 2007年第4期22卷 302-306页

作者：崔光磊周新红智林杰 Arne thomas Klaus m.llen 马普协会高分子所青岛科技大学化学与分子学院山东青岛266042 马普协会胶体界面所

报道了一种利用氧化硅模板,裂解简单易得的含钌有机物制备纳米结构炭/钌复合物的方法。在该复合物中,钌纳米颗粒均匀地分布在多孔的炭基体中。该复合物被电氧化所得炭/RuO.2xH2O的超级电容性质明显提高(10m./s时229F/g )。

关键词：电极纳米材料超级电容器炭钌

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Arterial throm.osis in the context of HCV-associated vascular disease can be prevented by protein C

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Cellular & m.lecular Im.unology 2017年第12期14卷 986-996页

作者： Philipp Blüm.Joachim.Pircher m.nika m.rkle thomas Czerm.k Andrea Ribeiro Hanna m.nnell Florian Krötz Alexander Hennrich m.chael Spannagl Sim.ne Köppel Erik Gaitzsch m.rkus Wörnle m.dizinische Klinik und Poliklinik iv InnenstadtKlinikum der Universität München80336 MünchenGermany Walter Brendel Centre of Experim.ntal m.dicine and m.nich Heart Alliance Ludwig Maximilians University München80336 MünchenGermany m.dizinische Klinik und Poliklinik I Klinikum der Universität München80336 MünchenGermany Abteilung für Transfusionsm.dizin Zelltherapeutika und HämostaseologieKlinikum der Universität München80336 MünchenGermany

Hepatitis C virus(HCV)infection is a m.jor problem.*** is not lim.ted to liver disease but is frequently com.licated by im.une-m.diated extrahepatic m.nifestations such as glom.rulonephritis or vasculitis.A fatal com.lication of HCV-associated vascular disease is ***:polyribocytidylic acid(poly(I:C)),a synthetic analog of viral RNA,induces a Toll-like receptor 3(TLR3)-dependent arteriolar throm.osis without significant throm.us form.tion in venules in *** procoagulant effects are caused by increased endothelial synthesis of tissue factor and PAI-1 without platelet *** addition to hum.n um.ilical endothelial cells(HUVEC),hum.n m.sangial cells(Hm.)produce procoagulatory factors,cytokines and adhesion m.lecules after stim.lation with poly(I:C)or HCV-containing cryoprecipitates from.a patient with a HCV infection as *** protein C(APC)is able to prevent the induction of procoagulatory factors in HUVEC and Hm. in vitro and blocks the effects of poly(I:C)and HCV-RNA on the expression of cytokines and adhesion m.lecules in Hm. but not in *** vivo,protein C inhibits poly(I:C)-induced arteriolar ***,endothelial cells are de facto able to actively participate in im.une-m.diated vascular throm.osis caused by viral ***,we provide evidence for the ability of protein C to inhibit TLR3-m.diated arteriolar throm.osis caused by HCV infection.

关键词： hepatitis C throm.osis toll-like receptor 3

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