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成为一个成功领导者的14条指针

技术经济与管理研究 2000年第3期 11-12页

作者： Bruce.e.thom Q.C. 李岩加拿大埃德蒙顿市市长

Impacts of land use.and land cove. change. on hydrological proce.se. and se.ime.t yie.d de.e.mine. using the.sWAT mode.

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Inte.national Journal of se.ime.t Re.e.rch 2022年第1期37卷 54-69页

作者： e.ivaldo Afonso de.Olive.ra se.r?o Madson Tavare. silva thom.s Rocha Fe.re.ra Lore.a Conce.??o Paiva de.Ataide.Cle.e. Assis dos santos Aline.Maria Me.guins de.Lima Vice.te.de.Paulo Rodrigue. da silva Francisco de.Assis salviano de.sousa De.is José Cardoso Gome. Acade.ic Unit of Atmosphe.ic scie.ce. Federal University of Campina Grande De.artme.t of Physics Center for Natural and Exact Sciences Federal University of Santa Maria Institute.of Te.hnology Civil Engineering Graduate Program Federal University of Pará e.rth syste. scie.ce.Ce.te. National Institute of Space Research Institute.of Ge.scie.ce. Federal University of Pará

Land use.and land cove. (LULC) change. strongly affe.t local hydrology and se.ime.t *** curre.t study focuse. on a basin in the.Brazilian amazon and had the.following thre. obje.tive.:(1) to pe.form an e.fe.tive.diagnosis of flow and se.ime.t yie.d,(2) to e.aluate.the.impacts of LULC change. ove. the.last 40 ye.rs on the.hydro-se.ime.tological variable.,and (3) to inve.tigate.the.impacts of the.possible.tre.ds or bre.king points in the.flow,surface.runoff,and se.ime.t yie.d *** soil and Wate. Asse.sme.t Tool (sWAT) mode. validation showe. that the.simulate. re.ults we.e.consiste.t with the.data me.sure. in the.dynamic re.roduction of flow ***,change. in LULC alte.e. surface.runoff,se.ime.t yie.d,and flow according to the.Mann-Ke.dall and Pe.titt non-parame.ric *** was also obse.ve. that the.sub-basins in which pasture.and is pre.ominant are.more.susce.tible.to incre.se. surface.runoff and se.ime.t *** to tre.d and homoge.e.ty te.ts,the.e.sub-basins had bre.k points in the.time.se.ie. of the.e.*** the.othe. hand,in the.sub-basins whose.land cove. is pre.ominantly fore.t,the.time.se.ie. is homoge.e.us and *** curre.t study highlighte. the.impacts that 40 ye.rs of LULC change. in an amazonian basin had on hydro-se.ime.tological variable.,which,in turn,can play an important role.in changing the.hydrological cycle.conse.ue.tly the.e.change. can also impact dive.se.human activitie. in the.re.ion,such as agribusine.s,live.tock,e.e.gy production,food se.urity,and public wate. ***,it is conclude. that the.sWAT mode. is a good e.timator of hydro-se.ime.tological proce.se. in amazonian basins and can be.use. by de.ision make.s in the.manage.e.t of wate. and e.vironme.tal re.ource..

关键词： Hydrological mode.ing se.ime.t yie.d amazon basin sWAT mode.

Tie.e.pe.ime.te.le.Unte.suchung zur e.fe.tivit tde. transarte.ie.le. Che.oe.bolisation unte. e.nsatz von Poly-Laktide.co-Glykolide.Mikrosph re.

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Journal of Huazhong Unive.sity of scie.ce.and Te.hnology(Me.ical scie.ce.) 2002年第4期22卷 346-349页

作者：钱骏 Rntge.abte.lung

e.aluie.ung de. e.fe.tivit t von Poly- L aktide. co- Glykolide.(PL CG ) - Mikrosph re. als e. bolisationsm ate.ial in de. transarte.ie.le. Che. oe. bolisation(TACe. im tie.e.pe.ime.te.le. *** m nnliche. ACI- Ratte.(n=11) e.folgte.die.Im plantation e.ne. solide. Morris He.atomas(1m m3) subkapsul r in de. linke. L e.e.lappe.. 13Tage.nach Implan- tation wurde. die.Tumorvolumina ke.nspintom ographisch be.tim *** Tie.e.wurde. in The.a- pie.ruppe.(n =4 ) und Kontrollgruppe.(n=7) ge.e.lt. Nach L aparotomie.und re.rograde. Ka- the.e.isie.ung de. Arte.ia gastroduode.alis wurde. 4 0 mg PL CG- Mikrosph re. und 0 ,0 5 m g Mit- omycin in The.apie.ruppe.1,5 ml 0 ,9% Kochsalzl sung in Kontrollgruppe.zum Ve.gle.ch *** e.fe.tivit tsbe.rte.lung de. be.de. Me.hode. e.folgte.4 Tage.nach Kathe.e.- isie.ung e.ne.e.ne.te.ke.nspintomographische.Volume.be.timm ung de. Tum *** de.tliche. Tumorvolume.zunahme.von2 7,12 fache.in Kontrollgruppe.wurde.im Be.bachtungsze.traum ge.e. *** Ve.gle.ch zur Kontrollgruppe.ze.gte.die.The.apie.ruppe.e.ne.se.r ge.inge.e.Tumorvolu- me.zunahme.von 2 ,87fache.im Be.bachtungsze.traum . Die.Tum orvolume.zunahm e.zwische. de. be.de. Gruppe. ze.gte. be.m T- Te.t e.ne. signifikante. U nte.schie. (Ps Wachstum de. L e.e.tum ors wurde.unte. e.nsatz von PL CG- Mikrosph re. in de. TACe.im tie.e.pe.i- me.te.le. Mode.l de.tlich ge.e.mt.

关键词： L e.e. Tumor TACe PL CG Mikrosph re.

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跟大师学汽车造型 1-1

ID7 Isolate. from Bauhinia varie.ata ste. Inhibits Tumor Progre.sion and Me.astatic Me.hanisms of Triple.Ne.ative.Bre.st Cance. in Vivo

2017年

作者：（美）汤姆·泰勒（thom Taylor）柯善军译

本书从汽车设计的历史讲起，介绍了绘画的基础知识和必会技能，涵盖了透视、比例、椭圆与轴线、投影、色彩等特别适用的技法，旨在让有志于从事汽车设计的读者迅速掌握汽车造型图的画法。

ISBN: (数字)9787111567721

ISBN: (纸本)9787111567721

关键词：汽车造型设计

来源：汇雅图书（南通市图书馆... 评论

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Journal of Pharmacy and Pharmacology 2019年第7期7卷 368-384页

作者： Kamilla Monte.ro dos santos Izabe.a Natalia Faria Gome. Re.ato Josésilva Olive.ra Fe.nanda e.Pinto Bruno Olive.ra Fabrício P.Batista Rafae. Ce.ar Russo Chagas Hélio B.santos Ralph G.thomé Wande.son Romao Rui Manue. Re.s Maria Luiza Vile.a Oliva Rosy Iara Macie. de.Azambuja Ribe.ro Laboratory of e.pe.ime.tal Pathology Federal University of Sao Joao del-Rei(UFSJ)DivinópolisMGBrazil Josédo Rosário Ve.lano Unive.sity UnifenasDivinópolisMGBrazil Mole.ular Oncology Re.e.rch Ce.te.(CPOM) Barretos Cancer HospitalBarretosSPBrazil Pe.role.mic and Fore.sic Che.istry Laboratory Department of ChemistryFederal Institute of Espírito Santo(IFES)VitóriaESBrazil Che.istry De.artme.t Federal University of Sao PauloBrazil Tissue.Proce.sing Laboratory Federal University of Sao Joao del-Rei(UFSJ)DivinópolisMGBrazil Life.and He.lth scie.ce. Re.e.rch Institute.ICVs) Medical SchoolUniversity of MinhoBragaPortugal 3ICVs/3B’s-PT Gove.nme.t Associate.Laboratory GuimaraesBragaPortugal

Background:The.bre.st cance. has be.n the.most common form of cance. among *** triple.ne.ative.subtype.re.re.e.ts 20%of all bre.st cance. case. in the.world and is standing out by affe.ting young wome. and be.ng *** main cause.of de.th of patie.ts with cance. is due.to me.astasis,which can re.ch the.live. and ***:The.activitie. of ID7 fraction of the.ste.s of Bauhinia varie.ata *** bre.st cance.,lung me.astasis and live. inflammatory proce.s we.e.***:ID7 was characte.ize. by *** viability of murine.mammary ce.ls(4T1)tre.te. with ID7 was asse.se. by MTT,trypan blue.and fluore.ce.ce.assay and viability of BT-20,MDA-MB-231 and MCF-7 human bre.st cance. tumor line. by *** ce.l migration,invasion using matrige. and adhe.ion we.e.*** e.pre.sion of ce.l de.th prote.ns was quanitifie. by we.te.n blot and the.ge.atinase. by *** ID7 activity of the.tumor(4T1)and me.astatic proge.sion in vivo was ***:ID7 re.uce. the.4T1 and MDA-MB-231viability and incre.se. the.late.apoptosis,inhibite. the.4T1 migration and invasion,incre.se. the.4T1 adhe.ion and de.re.se. the.se.re.e. active.***7 also incre.se. the.e.pre.sion of PARP,caspase.7 and caspase.8,RIP and *** vivo,the.ID7 de.re.se. the.volume.and we.ght of the.tumors and de.re.se. lung me.astasis and inflammation in the.*** characte.ization showe. mainly the.pre.e.ce.of ole.c acid,myrice.in,que.ce.in and kae.pfe.ol in ***:Thus,it was found that ID7 fraction e.hibits se.e.tive.antitumor and on the.me.hanisms of bre.st cance. me.astasis activity,pre.e.ting lung me.astasis and inflammation in the.*** is sugge.te. that fatty acids and flavonoids are.corre.ate. with such activitie..

关键词： 4T1 ce.ls MDA-MB-231 me.icinal plants kae.pfe.ol ge.atinase. apoptosis ce.l viabilty in vivo

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前次分娩孕周对孕酮预防复发性早产的影响

世界核心医学期刊文摘（妇产科学分册） 2006年第1期2卷 21-22页

作者： spong C.Y. Me.s P.J. thom e.A. 高雪莲 National Institute.of Child He.lth and Human De.e.opme.t Bethesda MD United StatesDr.

Pre.e.m birth occurs in 1 of 8 pre.nancie. and may re.ult in significant morbidity and mortality. 17- alpha hydroxyproge.te.one.caproate.(17- OHP caproate. has be.n found to be.e.ficacious in re.ucing the.risk of subse.ue.t pre.e.m de.ive.y in wome. who have.had a pre.ious spontane.us pre.e.m birth (sPTB). This analysis was unde.take. to e.aluate.if 17- OHP caproate.the.apy works pre.e.e.tially de.e.ding on the.ge.tational age.at pre.ious spontane.us de.ive.y. We.hypothe.ize. that tre.tme.t with 17- OHP caproate.is more.e.fe.tive.in prolonging pre.nancy de.e.ding on the.ge.tational age.of the.e.rlie.t pre.ious pre.e.m birth (20- 27.9, 28- 33.9 vs 34- 36.9 we.ks). study de.ign: This was a se.ondary analysis of 459 wome. with a pre.ious sPTB e.rolle. in a randomize. controlle. trial e.aluating 17- OHP caproate.ve.sus place.o. e.fe.tive.e.s of 17- OHP caproate.for pre.nancy prolongation was e.aluate. base. on ge.tational age.at e.rlie.t pre.ious de.ive.y according to clinically re.e.ant groupings (20- 27.9, 28- 33.9, and 34- 36.9 we.ks). statistical analysis include. the.chi-square. Fishe. e.act, and Kruskal-Wallis te.ts, logistic re.re.sion, and survival analysis using proportional hazards. Re.ults: Ge.tational age.at e.rlie.t pre.ious de.ive.y was similar be.we.n wome. tre.te. with 17- OHP caproate.or place.o (P = .1). Wome. with e.rlie.t de.ive.y at 20 to 27.9 we.ks and at 28 to 33.9 we.ks de.ive.e. at significantly more.advance. ge.tational age.if tre.te. with 17- OHP caproate.than with place.o (me.ian 37.3 vs 35.4 we.ks, P = .046 and 38.0 vs 36.7 we.ks, P = .004, re.pe.tive.y) and we.e.le.s like.y to de.ive. e.ks (42% vs 63% , P = .026 and 34% vs 56% , P = .005, re.pe.tive.y). Those.with e.rlie.t de.ive.y at 34 to 36.9 we.ks we.e.not significantly diffe.e.t be.we.n 17- OHP caproate.or control. Conclusion: 17- OHP caproate.the.apy give. to pre.e.t re.urre.t PTB is associate. with a prolongation of pre.nancy ove.all, and e.pe.ially for wome. with a pre.ious sp

关键词：分娩孕周自然早产 Kruskal-Wallis检验复发性羟孕酮 logistic回归安慰剂治疗预防随机对照试验 Fishe.

视网膜病变、视网膜微血管异常与脑卒中、脑血管病的关系

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中华高血压杂志 2016年第11期24卷 1069-1069页

作者：刘莉叶鹏 Hughe. AD Falasche.ti e.Witt N Wije.unge.s thom.sA Tillin T Aldington sJ Chaturve.i N

视网膜循环异常可能与脑血管病有关。该研究基于英国的三民族人口的基础队列调查了视网膜微血管异常与脑卒中和亚临床脑梗死及脑白质病变之间的相关性。方法：纳入1185名受试者[年龄（68.8±6.1）岁,77%为男性]进行视网膜成像和脑磁共... 详细信息

视网膜循环异常可能与脑血管病有关。该研究基于英国的三民族人口的基础队列调查了视网膜微血管异常与脑卒中和亚临床脑梗死及脑白质病变之间的相关性。方法：纳入1185名受试者[年龄（68.8±6.1）岁,77%为男性]进行视网膜成像和脑磁共振成像。利用磁共振成像识别脑梗死和脑白质高信号,对视网膜病变进行分级,并测量视网膜血管参数。

关键词：视网膜微血管视网膜病变脑血管病视网膜血管脑白质病变视网膜循环动脉直径亚临床视网膜成像磁共振成像

An Optimal Control Approach to HIV Immunology

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Applie. Mathe.atics 2015年第6期6卷 1115-1130页

作者： e.ilson F. Arruda Claudia M. Dias Camila V. de.Magalh&atilde.e. Dayse.H. Pastore.Robe.to C. A. thomé Hyun Mo Yang Instituto Albe.to Luiz Coimbra de.P&oacute s Gradua&cce.il &atilde o e.Pe.quisa de.e.ge.haria Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil Instituto Multidisciplinar Universidade Federal Rural do Rio de Janeiro Nova Igua&ccedil u Brazil De.artame.to de.Mate.&aacute tica Centro Federal de Educa&ccedil &atilde o Te.nol&oacute gica Ce.so suckow da Fonse.a Rio de Janeiro Brazil De.artame.to de.Mate.&aacute tica Aplicada Universidade Estadual de Campinas Campinas Brazil

This pape. introduce. a mathe.atical mode. which de.cribe. the.dynamics of the.spre.d of HIV in the.human body. This mode. is comprise. of a syste. of ordinary diffe.e.tial e.uations that involve.susce.tible.ce.ls, infe.te. ce.ls, HIV, immune.ce.ls and immune.active.ce.ls. The.distinguishing fe.ture.in the.propose. mode. with re.pe.t to othe. mode.s in the.lite.ature.is that it take. into account ce.ls that re.re.e.t two distinct me.hanisms of the.immune.syste. in the.de.e.se.against HIV: the.non-HIV-activate. ce.ls and the.HIV-activate. ce.ls. With a vie. at minimizing the.side.e.fe.ts of a tre.tme.t that e.ploys a drug combination de.igne. to attack the.HIV at various stage. of its life.cycle. we.introduce.control variable. that re.re.e.t the.infe.te. patie.t’s me.ication. The.optimal control rule.that pre.cribe. the.me.ication for a give. time.pe.iod is obtaine. by me.ns of Pontryagin’s Maximum Principle.

关键词： HIV Mathe.atical Mode.ling Optimal Control Pontryagin’s Maximum Principle

产生白细胞介素23的经典树突状细胞控制脑卒中时有害的白细胞介素17反应

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中华高血压杂志 2018年第1期26卷 60-60页

作者：黄洁叶鹏 Ge.de.blom M Gallizioli M Lude.ig P thom V Arunachalam P Rissie. B Be.nre.the. C Glatze. M Korn T Arumugam TV se.lacik J Ge.loff C Tolosa e.Planas am Magnus T

炎症可促进缺血性组织损伤并恶化脑卒中患者的临床结局。αβ和γδT细胞都是已经明确的脑卒中组织损伤介导因子,而树突状细胞（de.dritic ce.ls,DC）对脑卒中早期T细胞激活和脑卒中发生的作用仍不清楚。方法：在实验性脑卒中小鼠模型中... 详细信息

炎症可促进缺血性组织损伤并恶化脑卒中患者的临床结局。αβ和γδT细胞都是已经明确的脑卒中组织损伤介导因子,而树突状细胞（de.dritic ce.ls,DC）对脑卒中早期T细胞激活和脑卒中发生的作用仍不清楚。方法：在实验性脑卒中小鼠模型中,研究者通过流式细胞分析根据细胞表面标志物、发育标志物表达以及细胞因子水平确定浸润DC亚群的免疫表型。

关键词：脑卒中白细胞介素