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Establishing the role of detoxifying enzymes in field-evolved resistance to various insecticides in the brown planthopper （Nilaparvata lugens） in South India

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Insect Science 2017年第1期24卷 35-46页

作者： Vijayakumar Maheshwari Malathi Sushil K. Jalali Dandinashivara K. Sidde Gowda Muthugounder Mohan thiruvengadam venkatesan Division of Molecular Entomology ICAR-National Bureau of Agricultural Insect Resources Bengaluru 560 024 Karnataka India Department of Entomology College of Agriculture University of Agricultural Sciences-Bengaluru V.C. Farm Mandya 571 478 Karnataka India

The brown planthopper （BPH）, Nilaparvata lugens （Stal）, is one of the major pests of rice throughout Asia. Extensive use of insecticides for suppressing N. lugens has resulted in the development of insecticide resistance leading to frequent control failures in the field. The aim of the present study was to evaluate resistance in the field populations of N. lugens from major rice growing states of South India to various insecticides. We also determined the activity of detoxifying enzymes （esterases [ESTs], glutathione S- transferases [GSTs], and mixed-fimction oxidases [MFOs]）. Moderate levels of resistance were detected in the field populations to acephate, thiamethoxam and buprofezin （resistance factors 1.05-20.92 fold, 4.52-14.99 fold, and 1.00-18.09 fold, respectively） as compared with susceptible strain while there were low levels of resistance to imidacloprid （resistance factor 1.23-6.70 fold） and complete sensitivity to etofenoprox （resistance factor 1.05- 1.66 fold）. EST activities in the field populations were 1.06 to 3.09 times higher than the susceptible strain while for GST and MFO the ratios varied from 1.29 to 3.41 and 1.03 to 1.76, respectively. The EST activity was found to be correlated to acephate resistance （r = 0.999, P ≥ 0.001）. The high selection pressure of organophosphate, neonicotinoid, and insect growth regulator （IGR） in the field is likely to be contributing for resistance in BPH to multiple insecticides, leading to control failures. The results obtained will be beneficial to IPM recommendations for the use of effective insecticides against BPH.

关键词： esterases glutathione S-transferases insecticide resistance mixed function oxidases Nilaparvata lugens toxicological bioassay

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Air-stable,all-dry transferred ReS_(2)/GaSe heterostructure-based NO_(2)gas sensor

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Journal of Materials Science & Technology 2024年第1期168卷 79-87页

作者： A.venkatesan Hyeyoon Ryu Anupom Devnath Hyungyu Yoo Seunghyun Lee Department of Electronic Engineering Kyung Hee UniversityYongin-Si 17104South Korea Department of Electronics and Information Convergence Engineering Kyung Hee UniversityYongin-Si 17104South Korea

Two-dimensional(2D)materials have gained considerable attention in chemical sensing owing to their naturally high surface-to-volume ***,the poor response time and incomplete recovery re-strict their application in practical,high performance gas *** this work,we fabricated air-stable ReS_(2)/GaSe heterostructure-based NO_(2)gas sensors with excellent gas sensing response,recovery,selectiv-ity and a low limit of detection(LOD)toward nitrogen dioxide(NO_(2)).The ReS_(2)/GaSe heterostructure was prepared via mechanical exfoliation and an all-dry transfer *** the sensing measurements,temperature-dependant transport measurements were carried *** Schottky Barrier Height(SBH)of the ReS_(2)/GaSe heterostructure was calculated and the corresponding transport mechanisms were *** fabricated gas sensors showed a significant response enhancement with full reversibility to-ward ppm-level NO_(2)(response of∼17%at 3 ppm,a LOD of∼556 ppb)at an operating temperature of(33°C).In particular,the total response and recovery time of the ReS_(2)/GaSe was revealed to be less than 4 min(∼38 s and∼174 s,respectively)for the 250 ppm concentration,which is one of the best response and recovery time toward ppm-level NO_(2).The excellent sensing performances and recovery characteris-tics of the ReS_(2)/GaSe structure are attributed to its efficient charge separation,unique interlayer coupling and desirable band *** atomically thin,ultrasensitive gas sensor that operates at room tem-perature is a strong technological contender to conventional metal oxide gas sensors,which often require elevated temperatures.

关键词： 2D materials All-dry transfer Gas sensor Van der Waals heterostructure ReS_(2)/GaSe Gas sensing response Transition metal dichalcogenide

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Effectiveness of craniosacral therapy,Bowen therapy,static touch and standard exercise program on sleep quality in fibromyalgia syndrome:A randomized controlled trial

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Journal of Integrative Medicine 2024年第4期22卷 473-483页

作者： Reepa Avichal Ughreja Prem venkatesan Dharmanand Balebail Gopalakrishna Yogesh Preet Singh Vani Lakshmi R Department of Physiotherapy Manipal College of Health ProfessionsManipal Academy of Higher EducationManipal 576104KarnatakaIndia Department of Rheumatology Manipal HospitalBengaluru 560052KarnatakaIndia Department of Clinical Immunology and Rheumatology All India Institute of Medical SciencesBilaspur 174001Himachal PradeshIndia Department of Data Science Prasanna School of Public HealthManipal Academy of Higher EducationManipal 576104KarnatakaIndia

Background:Sleep disturbance is commonly seen in fibromyalgia syndrome (FMS);however,high quality studies involving manual therapies that target FMS-linked poor sleep quality are lacking for the Indian ***:Craniosacral therapy (CST),Bowen therapy and exercises have been found to influence the autonomic nervous system,which plays a crucial role in sleep *** the paucity of evidence concerning these effects in individuals with FMS,our study tests the effectiveness of CST,Bowen therapy and a standard exercise program against static touch (the manual placebo group) on sleep quality in ***,setting,participants and intervention:A placebo-controlled randomized trial was conducted on132 FMS participants with poor sleep at a hospital in *** participants were randomly allocated to one of the four study groups,including CST,Bowen therapy,standard exercise program,and a manual placebo control group that received static ***,Bowen therapy and static touch treatments were administered in once-weekly 45-minute sessions for 12 weeks;the standard exercise group received weekly supervised exercises for 6 weeks with home exercises until 12 *** 12 weeks,all study participants performed the standard exercises at home for another 12 *** outcome measures:Sleep quality,pressure pain threshold (PPT),quality of life and fibromyalgia impact,physical function,fatigue,pain catastrophizing,kinesiophobia,and positive–negative affect were recorded at baseline,and at weeks 12 and 24 of the ***:At the end of 12 weeks,the sleep quality improved significantly in the CST group (P=0.037) and Bowen therapy group (P=0.023),and the PPT improved significantly in the Bowen therapy group(P=0.002) and the standard exercise group (P<0.001),compared to the static touch *** improvements were maintained at 24 *** between-group differences were observed for other secondary ***:CST and Bowen therapy improv

关键词： Chronic pain Complementary therapies Exercise Fibromyalgia Musculoskeletal manipulations Sleep

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Spatial Attention Integrated EfficientNet Architecture for Breast Cancer Classification with Explainable AI

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Computers, Materials and Continua 2024年第3期80卷 5029-5045页

作者： Chakravarthy S. Nagarajan B. Khan S.B. venkatesan V.K. Ramakrishna M.T. Al Musharraf A. Aurungzeb K. Department of Electronics and Communication Engineering Bannari Amman Institute of Technology Sathyamangalam 638402 India School of Computer Science Engineering and Information Systems (SCORE) Vellore Institute of Technology Vellore 632014 India School of Science Engineering and Environment University of Salford Manchester M54WT United Kingdom Adjunct Research Faculty Centre for Research Impact and Outcome Chitkara University Rajpura 140401 India Department of Computer Science and Engineering Faculty of Engineering and Technology JAIN (Deemed-to-be University) Bengaluru 562112 India Department of Management College of Business Administration Princess Nourah Bint Abdulrahman University Riyadh 11671 Saudi Arabia Department of Computer Engineering College of Computer and Information Sciences King Saud University Riyadh 11543 Saudi Arabia

Breast cancer is a type of cancer responsible for higher mortality rates among women. The cruelty of breast cancer always requires a promising approach for its earlier detection. In light of this, the proposed research leverages the representation ability of pretrained EfficientNet-B0 model and the classification ability of the XGBoost model for the binary classification of breast tumors. In addition, the above transfer learning model is modified in such a way that it will focus more on tumor cells in the input mammogram. Accordingly, the work proposed an EfficientNetB0 having a Spatial Attention Layer with XGBoost (ESA-XGBNet) for binary classification of mammograms. For this, the work is trained, tested, and validated using original and augmented mammogram images of three public datasets namely CBIS-DDSM, INbreast, and MIAS databases. Maximum classification accuracy of 97.585% (CBIS-DDSM), 98.255% (INbreast), and 98.91% (MIAS) is obtained using the proposed ESA-XGBNet architecture as compared with the existing models. Furthermore, the decision-making of the proposed ESA-XGBNet architecture is visualized and validated using the Attention Guided GradCAM-based Explainable AI technique. © 2024 The Authors.

关键词： breast cancer deep-learning EfficientNet Explainable AI mammograms transfer learning

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Dietary Green Tea Extract and Antioxidants Improve Insulin Secretory Functions of Pancreatic β-Cells in Mild and Severe Experimental Rodent Model of Chronic Pancreatitis

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Open Journal of Endocrine and Metabolic Diseases 2024年第2期14卷 53-72页

作者： Galande Sheethal Ranjeet K. Tokala Pavan Pondugala Krishna Vemula Vijayalakshmi venkatesan Pothani Suresh Surya Satyanarayana Singh Guduru Venkat Rao Duvvur Nageshwar Reddy Mitnala Sasikala Basic Science and Translational Research Division Asian Healthcare Foundation AIG Hospitals Hyderabad India Division of Cell and Molecular Biology National institute of Nutrition Hyderabad India National Animal Resource Facility for Biomedical Research Hyderabad India Department of Biochemistry Osmania University Hyderabad India Department of Surgical Gastroenterology Asian Institute of Gastroenterology Hyderabad India Department of Gastroenterology Asian Institute of Gastroenterology Hyderabad India

Chronic pancreatitis (CP) is a progressive inflammatory disorder of the pancreas. It is predominantly idiopathic (with an unknown cause) in India and mostly due to alcohol in the West. Diabetes that occur secondary to chronic pancreatitis (T3c Diabetes) is often brittle, and is difficult to attain normoglycemia with conventional treatment requiring multiple doses of insulin. Mild and severe model of CP was induced in mice by repeated intraperitoneal injections of cerulein and L-arginine respectively with an intent to study islet dysfunction and develop therapeutic strategy in animal models of CP. Dietary intervention of epigallocatechin-3-gallate (EGCG) was tested in both the models of CP for its beneficial effects on insulin secretory functions. Pancreata collected upon euthanasia were used to study alterations in the morphology of pancreatic parenchyma and inflammation by staining with H&E and fibrotic changes by Masson’s trichrome and picrosirius staining. Insulin secretory functions of islets were evaluated to test the efficacy of the dietary intervention on β-cell functions. Intraperitoneal glucose tolerance test was performed to monitor the glucose homeostasis before and after the dietary intervention. Both the models resulted in CP with dispersed acini, inflammation and fibrosis. The loss of acini and extent of fibrosis was more in L-arginine model. 2-fold improvement in glucose-stimulated insulin secretory functions of islets was observed with 0.5% EGCG dietary intervention in cerulein model of CP and 1.6-fold in L-arginine model of CP. A further improvement in insulin secretion by 3.2-fold was observed with additional dietary supplements like N-acetyl cysteine, curcumin in combination with EGCG. Our results thus demonstrate and highlight the therapeutic potential of dietary green tea (EGCG) supplementation in reversing islet dysfunction and improving glucose homeostasis in experimental chronic pancreatitis in mice.

关键词： Dietary Intervention C57BL6/J Mice Epigallocatechin-3-Gallate N-Acetyl Cysteine Curcumin Chronic Pancreatitis Islets Glucose Stimulated Insulin Secretion

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Application of Pomegranate Rind Extract for Improvement of Functional Properties of Various Materials—A Critical Review

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Open Journal of Composite Materials 2024年第2期14卷 71-90页

作者： Habeebunissa Nooman Narayanan Gokarneshan Murugan Umamaheswari Muthumani Dhiliphan Kumar Usha Kumari Ratna Jayagopal Lavanya Senthamarai Kannan Umamageshwari Sona Mohandas Anton Zahurudeen Shahanaz venkatesan Sathya David Piriadarshani Chokkanathan Kayalvizhi Department of Knitwear Design National Institute of Fashion Technology Chennai India Department of Textile Chemistry SSM College of Engineering Komarapallayam India Department of Management Studies Dr. SNS Rajalakshmi College of Arts and Science Coimbatore India Department of Business Administration Kalasalingam Business School Kalasalingam Academy of Research and Education Srivilliputhur India Department of Textiles and Clothing Avinashi Lingam Institute for Home Science and Higher Education for Women Coimbatore India Department of Fashion Design SRM Institute of Science and Technology (Kattankalathur) Chennai India Department of Fashion Design Hindustan Institute of Technology and Science Chennai India Department of Fashion Design SRM Institute of Science and Technology (Ramapuram) Chennai India Department of Mathematics Hindustan Institute of Technology and Science Chennai India Department of Textile Technology Jaya Engineering College Tiruninravur India

Pomegranate rind is abundantly available as a waste material. Pomegranate Rind Extract (PRE) can be applied to cotton fabrics for its natural colours, as a mordanting agent and also for imparting certain functional properties such as fire retardancy and antimicrobial properties. This paper reviews the feasibility of Pomegranate Rind Extract to improve the functional properties of cellulosic fabrics. Studies show that varying concentrations and higher temperatures that were used to apply the extract on the fabric, resulted in enhanced functional properties. At a particular concentration, the treated fabric showed a 15 times lower burning rate in comparison with the control fabric. Also, antimicrobial efficacy has been observed against Gram-positive and Gram-negative bacteria. Due to the natural colouring material, it can be used as a natural dye on cotton material. The fire retardancy of pomegranate rind extract was tested on jute material under varying alkalinity. Research has indicated that pomegranate rind extract could be used to dye polyamide as well. The rubbing and wash fastness of the finished fabrics is good. The light fastness was fair, and its antibacterial efficiency against tested bacteria was good.

关键词： Natural Polymers Synthetic Polymers Pomegranate Rind Extract (PRE) Dyeing Functional Property

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Fully covered metal biliary stents: A review of the literature

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World Journal of Gastroenterology 2021年第38期27卷 6357-6373页

作者： Robert Lam thiruvengadam Muniraj Department of Medicine Yale University School of MedicineNew HavenCT 06520United States

Fully covered self-expandable metal stents(FCSEMS)represent the latest advancement of metal biliary stents used to endoscopically treat a variety of obstructive biliary pathology.A large stent diameter and synthetic covering over the tubular mesh prolong stent patency and reduce risk for tissue hyperplasia and tumor ***,FCSEMS can be easily *** these features address issues faced by plastic and uncovered metal *** purpose of this paper is to comprehensively review the application of FCSEMS in benign and malignant biliary strictures,biliary leak,and post-sphincterotomy bleeding.

关键词： Fully covered self-expandable metal stents Plastic stents Endoscopy Chronic pancreatitis Biliary stricture Biliary leak Stent migration

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DPM simulation in an underground entry: Comparison between particle and species models

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International Journal of Mining Science and Technology 2016年第3期26卷 487-494页

作者： thiruvengadam Magesh Zheng Yi Tien Jerry C. Department of Mining & Nuclear Engineering Missouri University of Science & Technology Division of Mining and Resources Engineering Department of Civil Engineering Monash University

The diesel particulate matter(DPM) emission from diesel powered equipment in underground mines can cause health hazards including cancer to the miners. The understanding of the DPM propagation pattern under realistic mining condition is required for selecting proper DPM control strategies and to improve working practices in underground mines. In this paper, three dimensional simulations of DPM emission from the exhaust tail pipe of a load-haul-dump(LHD) vehicle and its subsequent distribution inside an isolated zone in the typical underground mine are carried out using two different solution models available in Ansys Fluent. The incoming fresh air into the isolated zone is treated as a continuous phase and DPM is treated either as a continuous phase(gas) or as a secondary discrete phase(particle). Species transport model is used when DPM is treated as gas and discrete phase model is used when DPM is assumed to behave like a particle. The distributions of DPM concentration inside the isolated zone obtained from each method are presented and compared. From the comparison results, an accurate and economical solution technique for DPM evaluation can be selected.

关键词： CFD Dead-end DPM Discrete phase model Species transport model

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Characterization and optimization of pulse electrodeposition of Ni/nano-Al_2O_3 composite coatings

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International Journal of Minerals,Metallurgy and Materials 2013年第5期20卷 479-485页

作者： A.Jegan R.venkatesan Department of Mechanical Engineering Sona College of Technology

Nickel/nano-A1203 composite coatings produced by the pulse electrodeposition method and the influence of pulse parameters, i.e., pulse frequency, duty cycle, and current density on the microstructure, hardness, and corrosion resistance, were critically investigated on an AISI 1018 mild steel specimen electroplated in a Watt＇s type bath. The experiments were carried out with different combinations of pulse parameters using Taguchi＇s L27 orthogonal array, and 27 trials were conducted to study the effect of pulse parameters in view to maximize the hardness of the specimen. The assessment results clearly reveal that the specimen exhibits the maximum hardness at the pulse frequency of 20 Hz, duty cycle of 30%, and peak current density of 0.4 A/cm2, which are designated as the optimal parameters herein. Furthermore, the influences of those optimized pulse parameters over the microstructure and corrosion resistance were investigated, and some conclusions were drawn. Also, from the ANOVA examination, it is clear that duty cycle is predominant in affecting the hardness, while current density has relatively low impact.

关键词： composite coatings nickel alumina nanoparticles electrodeposition corrosion resistance hardness

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Reconfigurable Logic Design of CORDIC Based FFT Architecture for 5G Communications

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Intelligent Automation & Soft Computing 2023年第6期36卷 2803-2818页

作者： C.thiruvengadam M.Palanivelan Department of Electronics and Communication Engineering Anjalai Ammal Mahalingam Engineering CollegeThiruvarur614403TamilnaduIndia Department of Electronics and Communication Engineering Rajalakshmi Engineering CollegeChennai602105TamilnaduIndia

There are numerous goals in next-generation cellular networks(5G),which is expected to be available *** want to increase data rates,reduce end-to-end latencies,and improve end-user service *** networks need to change because there has been a significant rise in the number of base stations required to meet these needs and put the operators’low-cost constraints to the *** it can withstand interference from other wireless networks,and Adaptive Complex Multicarrier Modulation(ACMM)system is being looked at as a possible choice for the 5th Generation(5G)of wireless *** arithmetic units need to be used on the hardware side of multicarrier systems to do the pulse-shaping filters and inverse *** main goal of this study is to adapt complex multicarrier modulation(ACMM)for baseband transmission with low complexity and the ability to change *** found that this is the first recon-figurable architecture that lets you choose how many subcarriers a subband has while still having the same amount of hardware resources as ***,under the new design with a single selection line,it selects from a set of *** baseband modulating signal is evaluated and tested using a Field-Programmable Gate Array(FPGA)*** device is available from a commercial *** technology outperforms current technology in terms of computational com-plexity,simple design,and ease of ***,it has a higher power spectrum density,spectral efficiency,a lower bit error rate,and a higher peak to average power ratio than existing technology.

关键词： Error analysis pulse-shaping filters reconfigurable architectures FBMC OFDM UFMC

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