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Elimination of extraordinarily high cracking susceptibility of aluminum alloy fabricated by laser powder bed fusion

Journal of Materials Science & Technology 2022年第8期103卷 50-58页

作者： Holden Hyer Le Zhou Sharon Park thinh huynh Abhishek Mehta Saket Thapliyal Rajiv S.Mishra Yongho Sohn Department of Materials Science and Engineering University of Central FloridaOrlandoFLUSA Center for Friction Stir Processing Department of Materials Science and EngineeringAdvanced Materials and Manufacturing Processes InstituteUniversity of North TexasDentonTXUSA Now Research Scientist Oak Ridge National LaboratoryOak RidgeTNUSA Now Assistant Professor Marquette UniversityMilwaukeeWIUSA Now PhD Candidate Johns Hopkins UniversityBaltimoreMDUSA

Using the calculation of phase diagrams approach and Scheil solidification modeling,the Al-2.5Mg-1.0Ni-0.4Sc-0.1Zr alloy was designed,intentionally with an extraordinarily high cracking susceptibility,making it prime for solidification cracking during laser powder bed *** study demonstrates the ability to mitigate even the most extreme solidification cracking tendencies in aluminum alloys with only minor alloying additions of Sc and Zr,0.5 wt.%***,by employing a simple direct ageing heat treatment,good tensile mechanical properties were observed with a yield strength of 308 MPa,an ultimate tensile strength of 390 MPa,and a total elongation of 11%.

关键词： Additive manufacturing Cracking susceptibility Aluminum alloy CALPHAD Mechanical properties

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High-dose methylprednisolone pulse therapy for the treatment of patients with severe COVID-19: Results from a prospective observational study

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Journal of Intensive Medicine 2022年第3期2卷 197-198页

作者： thinh N.Bui Hoang-Anh Ngo Nhat M.huynh Nguyen-Huy Do-Tran Lac Duy Le Thu-Anh Nguyen COVID-19 Intensive Care Unit 2 Thu Duc City HospitalThu Duc CityHo Chi Minh CityTam Phu 721400Vietnam Woolcock Institute of Medical Research 298 Kim MaBa DinhHanoi 118000Vietnam Usher Institute Old Medical SchoolUniversity of EdinburghEdinburgh EH89AGUnited Kingdom School of Medicine Vietnam National UniversityDong HoaHo Chi Minh CityDi AnBinh Duong 590000Vietnam Sydney School of Medicine The Faculty of Medicine and HealthThe University of SydneyCamperdownNSW 2050Australia

To the Editor:Recent randomized controlled trials,as well as high-quality systematic reviews and meta-analyses,strongly support the use of corticosteroids in patients with coronavirus disease 2019(COVID-19)who require oxygen support.[1]The use of pulse cor-ticosteroid therapy has been reported in case series and studies,showing significant improvement in patients and a reduction in mortality rate.[2]In this letter,we report the mortality rate among patients with severe COVID-19 receiving pulse corticos-teroids with methylprednisolone(500 mg/day)for≥3 days and≥24 h before intubation(median duration of therapy:3 days)compared with standard of care.

关键词： patients mortality therapy

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