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Entomotaxonomia 2003年第1期25卷 45-50页

作者：田明义 thierry DEUVE 华南农业大学资源环境学院广东广州510642 法国国家自然历史博物馆昆虫室巴黎f75005

Three new species of Orthogonius Macleay (Coleoptera, Caraboidea) from Malaya Peninsula are described and illustrated in the present papr: O. solidicornis, sp. nov. (from Singapore), O. morvani, sp. nov. a... 详细信息

关键词： Coleoptera Caraboidea Orthogoniini Orthogonius new species Thailand Singapore

Host/genetic factors associated with COVID-19 call for precision medicine

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Precision Clinical Medicine 2020年第3期3卷 228-234页

作者： Alain R.thierry Research Institute of Cancerology of Montpellier INSERM U1194IRCMICMMontpellier UniversityMontpellier F-34298France

If the current rate of infection are to be better managed,and future waves of infection kept at bay,it is absolutely necessary that the conditions and mechanisms of exposure to Severe Acute Respiratory Syndrome-Coronavirus 2(SARS-CoV-2)be better understood,as well as the downstream severe or lethal clinical *** the identification of notable comorbidities has now helped to define broad risk groups,the idiosyncratic responses of individual patients can generate unexpected clinical deterioration that is difficult to predict from initial clinical ***,physicians caring for patients with COVID-19 face clinical dilemmas on a daily *** ability to decipher individual predispositions to SARS-CoV-2 infection or severe illness,in light of variations in host immunological and inflammatory responses,in particular as a result of genetic variations,would be of great benefit in infection *** this end,this work associates the description of COVID-19 clinical complications,comorbidities,sequelae,and environmental and genetic *** also give examples of underlying genomic susceptibility to COVID-19,especially with regard to the newly reported link between the disease and the unbalanced formation of neutrophil extracellular *** a consequence,we propose that the host/genetic factors associated with COVID-19 call for precision medicine in its *** is to our knowledge the first article describing elements towards precision medicine for patients with COVID-19.

关键词： COVID-19 neutrophil extracellular traps sequelae genetic factors host factors circulating DNA

Descriptions of Three New Species of Orthogoniini (Coleoptera: Caraboidea) from Sumatra Island, Indonesia

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Entomotaxonomia 2004年第1期26卷 23-28页

作者：田明义 thierry DEUVE 华南农业大学资源环境学院广东广州510642 法国国家自然博物馆昆虫室巴黎f75005

In the present paper, two new species of Orthogonius Macleay and one new species of Hexachaetus Chaudoir (Coleoptera, Caraboidea, Orthogoniini) are described and illustrated from Sumatra Island, Indonesia.

关键词： Coleoptera Caraboidea Orthogoniini Orthogonius Hexachaetus new species Sumatra

A Provisional Species Checklist of the Oriental Orthogoninae (Coleoptera:Caraboidea)

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Entomotaxonomia 2010年第B8期32卷 137-148页

作者：田明义 thierry Deuve 华南农业大学资源环境学院广东广州510640 巴黎自然博物馆系统学及进化学部

A provisional species checklist of the Oriental subfamily Orthogoninae is provided. Orthogonius dupuisi Tian et Deuve, 2006 （from Indonesia） is treated as a junior homonym of O. dupuisi Basilewsky, 1948 （from Rhodesia）, and therefore O. dupuisianus n. nom. is proposed. Actenocus punctatus Tian et Deuve, 2006 is confirmed as a good species, rather than a junior synonym of Orthogonius crassicrus Chaudoir, 1871 proposed by Kirschenhofer （2010）.

关键词： Coleoptera Caraboidea Orthogoninae Checklist Oriental homonymy

Effect of Electrolyte Nature on Micellar Soft-Template Electropolymerization in Organic Solvent to Form Nanoporous Polymer Films with a Bioinspired Strategy

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Journal of Bionic Engineering 2022年第2期19卷 547-553页

作者： Caroline Fradin Francois Orange Sonia Amigoni Frédéric Guittard thierry Darmanin NICE Lab UniversitéCote d’Azur06100 NiceFrance Centre Commun de Microscopie Appliquée(CCMA) UniversitéCote d’Azur06100 NiceFrance

Here,using a bioinspired approach,the soft-template electropolymerization of naphtho[2,3-b]thieno[3,4-e][1,4]dioxine(NaphDOT)was conducted in dichloromethane with different water content,and using different supporting *** role of the electrolytes in the formation of reverse micelles that constitutes the soft template is *** reverse micelles stabilized by the electrolyte and the monomer were observed by TEM and related to the various porous nanostructures of the obtained polymer *** show that the nature of the electrolyte is not only fundamental for the formation of reverse micelles and thus porous nanostructures,but also plays a huge role in the good deposition of the oligomers upon the soft *** with nanostructures such as nanotubes,nanorings or nanomembranes were realized.

关键词： Electropolymerization Soft template Reverse micelles Porous nanostructures

Surface Nanostructure Control with Poly(ethylene glycol)(PEG)Spacer by Templateless Electropolymerization

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Journal of Bionic Engineering 2021年第1期18卷 65-76页

作者： Imen Bousrih Mejda El Kateb Mohammed Beji Fréderic Guittard thierry Darmanin University of Tunis El Manar Laboratory of Structural Organic ChemistryFaculty of Sciences of TunisTunis 2092Tunisia Universite Cote d'Azur NICE LabParc Valrose Nice 06100France

Controlling the shape of surface nanostructures is fundamental for various potential applications for cxamples,in water harvesting systems,liquid transportation or oil/water separation *** this paper,the creation of porous surface structures is made by a process called templateless electropolymerization,in which water(H_(2)0)is oxidizedreduced to form gas(O_(2)/H_(2))bubbles onto the surfaces and acting as soft template for the polymer *** the monomer(thieno[3,4-b]lhiophene)and the substituent(pyrene)constant,we demonstrate how a flexible PEG spacer can affect the structure *** the PEG spacer increases,the structures change frorm nanotubes(1D growth)to nanoribbons(2D)and after to hollow nanospheres(3D),which also affeets the wettig propertics.

关键词： nanostructures wettability hydrophobicity electrochemistry bioinspiration

Effect of asymmetric rolling on mechanical characteristics,texture and misorientations in ferritic steel

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Journal of Central South University 2013年第6期20卷 1443-1455页

作者： Wrofiski Sebastian Wierzbanowski Krzysztof Bacroix Brigitte Chauveau thierry Wrobel Mirostaw AGH University of Science and Technology Faculty of Physics and Applied Computer Science Krak6w 30-059 Poland LSPM-CNRS Universit6 Paris 13 Villetaneuse 93 430 France AGH University of Science and Technology Faculty of Metals Engineering and Industrial Computer Science Krak6w 30-059 Poland

The mechanical and microstructural properties as well as crystallographic textures of asymmetrically rolled low carbon steel were *** modelling of plastic deformation was carried out in two scales:in the macro-scale,using the finite elements method,and in the crystallographic scale,using the polycrystalline deformation *** internal stress distribution in the rolling gap was calculated using the finite elements method and these stresses were then applied to the polycrystalline elasto-plastic deformation *** mechanical properties,namely residual stress distribution,deformation work,applied force and torques,and bend amplitude,were *** diffraction measurements,X-ray and electron backscatter diffraction,enabled the examination of texture heterogeneity and selected microstructure *** predicted textures agree well with those determined *** plastic anisotropy of cold rolled ferritic steel samples,connected with texture,was expressed by Lankford coefficient.

关键词： asymmetric rolling crystallographic texture residual stress deformation model finite elements method diffraction

Artificial light at night decreases the pupillary light response of dark-adapted toads to bright light

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Integrative Zoology 2023年第5期18卷 867-875页

作者： Jean SECONDI Madeleine F.SCRIBA Nathalie MONDY thierry LENGAGNE Univ Lyon UniversitéClaude Bernard Lyon 1CNRSENTPEVilleurbanneFrance Facultédes Sciences Universitéd’AngersAngersFrance

Artificial light at night(ALAN)is expanding *** physiological effects have been reported in animals,but we still know little about the consequences for the visual *** pupil contributes to control incoming light onto the *** increases in light intensity evokes the pupil light reflex(PLR).Intrinsically photosensitive retinal ganglion cells(ipRGC)affect PLR and melatonin expression,which largely regulate circadian rhythms and PLR *** receive inputs from various photoreptors with different peak sensitivities implying that PLR could be altered by a broad range of light *** predicted ALAN to enhance *** to our prediction,dark-adapted cane toads Rhinella marina,exposed to ALAN(5 lx)for 12 days,exhibited a lower PLR than controls and individuals exposed to 0.04 lx,even after 1 h in bright *** cannot conclude whether ALAN induced a larger pupil size in dark-adapted toads or a slower initial ***,the response was triggered by a light source with an emission peak(590 nm)well above the sensitivity peak of melanopsin,the main photoreceptor involved in ***,ALAN alters the capacity of toads to regulate the incoming light in the eye at night,which may reduce the performance of visually guided behaviors,and increase mortality by predators or road kills at *** first study emphasizes the need to focus on the effect of ALAN on the vision of nocturnal organisms to better understand how this sensory system is altered and anticipate the consequences for organisms.

关键词： amphibian anuran light pollution pupillary light reflex vision

Optimizing stem cells for cardiac repair:Current status and new frontiers in regenerative cardiology

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World Journal of Stem Cells 2017年第1期9卷 9-25页

作者： Shant Der Sarkissian thierry Lévesque Nicolas Noiseux Department of Surgery Faculté de Médecine Université de MontréalMontrealQC H3C 3J7Canada Facultéde Médecine Universitéde MontréalMontrealQC H3C 3J7Canada

Cell therapy has the potential to improve healing of ischemic heart, repopulate injured myocardium and restore cardiac function. The tremendous hope and potential of stem cell therapy is well understood, yet recent trials involving cell therapy for cardiovascular diseases have yielded mixed results with inconsistent data thereby readdressing controversies and unresolved questions regarding stem cell efficacy for ischemic cardiac disease treatment. These controversies are believed to arise by the lack of uniformity of the clinical trial methodologies, uncertainty regarding the underlying reparative mechanisms of stem cells, questions concerning the most appropriate cell population to use, the proper delivery method and timing in relation to the moment of infarction, as well as the poor stem cell survival and engraftment especially in a diseased microenvironment which is collectively acknowledged as a major hindrance to any form of cell therapy. Indeed, the microenvironment of the failing heart exhibits pathological hypoxic, oxidative and inflammatory stressors impairing the survival of transplanted cells. Therefore, in order to observe any significant therapeutic benefit there is a need to increase resilience of stem cells to death in the transplant microenvironment while preserving or better yet improving their reparative functionality. Although stem cell differentiation into cardiomyocytes has been observed in some instance, the prevailing reparative benefits are afforded through paracrine mechanisms that promote angiogenesis, cell survival, transdifferentiate host cells and modulate immune responses. Therefore, to maximize their reparative functionality, ex vivo manipulation of stem cells through physical, genetic and pharmacological means have shown promise to enable cells to thrive in the postischemic transplant microenvironment. In the present work, we will overview the current status of stem cell therapy for ischemic heart disease, discuss the most recurring c

关键词： Stem cell Regenerative medicine Cellular cardiomyoplasty Preconditioning Myocardial infarction Heart failure Viability Paracrine activity Transplantation Pharmaco-optimizer

A NEW EXPLICIT SIMULATION FOR MOULD FILLING WITH HIGH VISCOUS FEEDSTOCK

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Acta Mechanica Solida Sinica 2004年第4期17卷 347-352页

作者： Cheng Zhiqiang Barriere thierry Liu Baosheng Gelin Jean Claude Department of Applied Mechanics Southwest Jiaotong UniversityChengdu 610031China LMARC University of Franche-Comte and CNRS24 Chemin de l’′epitapheBesancon 25000France

In the simulation of the metal injection moulding (MIM), the behaviours of feedstock are much di?erent from which of the polymer injection. It is a mixture of the metallic powder in high concentration and some plastic binder. The advance in simulation of the mould ?lling with such high viscous feedstock is featured by the development of a fully explicit vectorial algorithm. On the basis of previous explicit software realized by the authors, the new algorithm avoids the global solution for pressure ?elds and the use of MINI elements to improve its e?ciency. Except for the operations at element level, neither global solution nor the construction of global matrix is required in simulation. A special strategy is used to regulate the incompressibility condition in ?lled domain at each time step. In case of the MIM problems, this method provides a fast way to simulate the ?lling processes. The computational cost is about linearly proportional to the degree of freedom number. Moreover, this vectorial algorithm can be easily parallelized for high performance computation with multi-clusters. The comparison of numerical results with previous simulations on 3D cases proves the validity and e?ciency of new algorithm.

关键词： mould filling high viscosity explicit simulation vectorial algorithm