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ADEFGuard:Anomaly detection framework based on Ethereum smart contracts behaviours

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Blockchain(Research and Applications) 2023年第3期4卷 88-97页

作者： Malaw Ndiaye thierno Ahmadou diallo Karim Konate Computer Science Department UCAD DakarSenegal Computer Science Department UASZ ZiguinchorSenegal

Smart contracts are the building blocks of blockchain systems that enable automated peer-to-peer transactions and decentralized *** contracts certainly provide a powerful functional surplus for maintaining the consistency of transactions in applications governed by blockchain *** contracts have become lucrative and profitable targets for attackers because they can hold a large amount of *** verification and symbolic analysis have been employed to combat these destructive scams by analysing the codes and function calls,yet each scam's vulnerability should be discreetly *** this work,we introduce ADEFGuard,a new anomaly detection framework based on the behaviour of smart contracts,as a new *** design a learning and monitoring module to determine fraudulent smart contract *** framework is advantageous over basic algorithms in three ***,ADEFGuard provides a unified solution to different genres of scams,relieving the need for code analysis ***,ADEFGuard's inference is orders of magnitude faster than code ***,the experimental results show that ADEFGuard achieves high accuracy(85%),precision(75%),and recall(90%)for malicious contracts and is potentially useful in detecting new malicious behaviours of smart contracts.

关键词： Blockchain Smart contract Security Anomaly

Vapor intrusion in buildings: Development of semi-empirical models including lateral separation between the building and the pollution source

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Building Simulation 2022年第12期15卷 2031-2049页

作者： Juan Sebastian Rios Mora thierno diallo Bernard Collignan Marc Abadie Karim Limam Centre Scientifique et Technique du Batiment Health and Comfort DepartmentSaint-Martin-d'HèresCO 38400France University of La Rochelle Laboratoire des Sciences de I'Ingénieur pour I'Environnement-LaSIE UMR CNRS 7356La RochelleCO 17042France

Future constructions in the context of the industrial wastelands reuse may be exposed to Vapor Intrusion(VI).VI can be evaluated by combining in-situ measures and analytical models to evaluate exposure risk in future indoor ***,the assumptions in the existing models may reduce their accuracy when they do not meet the characteristics of real *** estimations of indoor concentration levels may lead to inappropriate solutions against *** this context,new semi-empirical models(SEM)are proposed in order to better specify pollution scenarios and thus increase the accuracy of VI *** development is based on a parametric study(numerical CFD)and a dimensionless analysis combined to existing VI models that consider a continuous source distribution in the *** expressions allow to better take into account the source position in the soil(*** and lateral source/building separation),soil properties(air permeability,diffusion coefficient of the pollutant,…)and building features(building foundation,indoor pressure,air exchange rate,…)in the estimation of indoor concentration *** obtained results with the proposed SEM were compared with a numerical CFD model and available experimental data,showing good accuracy in the estimation of *** the advantages of these new models,they can provide better precision in the health risk assessments associated with ***,these expressions can be easily integrated into building ventilation codes allowing to consider air exchange rate and indoor pressure variations over time.

关键词： indoor air quality lateral source/building distance polluted soils semi-empirical models vapor intrusion

Construction Project Management Using 5D BIM: Solution for Delay and Cost Overrun

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Construction Project Management Using 5D BIM: Solution for D...

作者： diallo thierno SOULEYMANE 绍兴文理学院

学位级别：硕士

为了成功地实现建设项目,传统项目管理的目标是进行任务协调,以在合同规定时间及预算内成功及按时交付项目。为此,必须在确定的时间范围和预算内实现某些项目目标。延迟和成本超支是两个主要缺陷,因为它们会干扰项目的成功。为了使施工...

为了成功地实现建设项目,传统项目管理的目标是进行任务协调,以在合同规定时间及预算内成功及按时交付项目。为此,必须在确定的时间范围和预算内实现某些项目目标。延迟和成本超支是两个主要缺陷,因为它们会干扰项目的成功。为了使施工过程更快、更安全、更方便和更精确,仍然存在各种挑战,因为该行业遭受质量差、通信差、成本超支和项目完成延误的困扰。建筑信息模型(BIM)的兴起是一项可选的创新,它可以解决与业务成本和时间控制相关的问题,因为它可以有效地扩大合作伙伴之间的协作。对BIM应用程序的检查表明,大多数应用程序旨在最大程度地减少建筑成本和项目时间。3D模型是几何模型,当附加时间时成为4D和附加成本时成为5D。这种方法使承包商能够可靠地确定项目成本,预期成本内的进度计划,同时允许通过考虑从模型中得出的材料数量和施工团队的生产率来优化进度计划。这项研究的目的是提供对建筑行业中BIM5D的清晰理解,基于BIM的第五维度(BIM 5D)及其应用程序,我们可以很好地描述结合了3D设计和结构的结构系统。预算和进度表为建筑项目管理提供5D工具,通过查看相应的优势、困难和动机因素有利于应用。

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Epidemiological Aspect and Evaluation of the Management of Urologic Emergencies at the Urology Unit of Labe Regional Hospital

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Open Journal of Urology 2023年第10期13卷 441-452页

作者： Kindy diallo mamadou Madiou Barry Aldoul Aziz Bah thierno Oumar diallo mamadou Bissiriou Bah thierno mamadou Oury diallo Abdoulaye Bobo diallo Oumar Raphiou Bah Urology Department Unit d’Urology Hospitol Régional Labé Guinea

Aim: To contribute to improving the management of urological emergencies at Labé Regional Hospital. Patients and Method: This was a dynamic, descriptive study lasting six months from July 1 to December 31, 2017. Results: Urological emergencies represented 45.14% (n = 218) of all admissions to the urology unit. The mean age of our patients was 56.60 years with extremes of fifteen days and 93 years. The 71 - 80 age group was the most represented with 28.03% (n = 61) followed by 61 - 70 years with 24.31% (n = 53). Our patients’ activities were dominated by agriculture, with 35.77% (n = 88), and the city center was most affected by urological emergencies, with 39.44% of cases (n = 86). 70.18% (n = 153) of our patients had bladder retention on admission, and 53.21% (n = 116) underwent urethral catheterization, including 3 women. The etiology of bladder retention in these 3 women was dominated by two cases of bladder lithiasis and one case of neurological bladder. Conclusion: The management of urological emergencies requires specific material and human resources. Their knowledge will enable us to better understand this problem and could serve as a basis for a broad reflection on the organization of the management of urological emergencies in our region.

关键词： Urological Emergencies Epidemiology Labé Regional Hospital

Nutritional Profile of Children with Major Sickle Cell Syndrome at the Centre of Medical and Health Advice of Kipé, Conakry, 2018

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Case Reports in Clinical Medicine 2024年第3期13卷 73-84页

作者： mamadou Aliou Doukoure Ibrahima Sory diallo M’mah Aminata Bangoura Amadou Oury Toure mamadou Moustapha Diop Fatoumata Binta diallo Mohamed Sama cherif thierno Saidou diallo Saidouba cherif Camara Abdoulaye Toure Faculty of Health Science and Technology Gamal Abdel Nasser University Conakry Guinea National AIDS Control Programme Ministry of Health Gamal Abdel Nasser University Conakry Guinea

Introduction: Growth is a reflection of a child’s health and nutritional status. Children with sickle cell disease often have slower statural and weight development. The aim of this study was to evaluate the nutritional profile of children with sickle cell disease (SCD) registered in the CEMECO centre database. Methodology: This was a cross-sectional study with simple random sampling of children aged 1 to 16 years registered in the clinic database. Results: We collected information on 208 children, 121 of whom had sickle cell disease and 87 of whom were normal, with a sex ratio of 1.02. The mean age of the sickle cell patients was 8.7 ± 4.4 years, while that of the non-sickle cell patients was 9.5 ± 4 years. Haemoglobin electrophoresis revealed 103 homozygous (SS), 18 double heterozygous (SC, SBetaThal, SE) and 87 normal (AA) and/or sickle cell trait (AS) sickle cell cases. We observed a significant difference in the height/age ratio (P ¥). Conclusion: The results of our study revealed stunted growth in children with sickle cell disease.

关键词： Sickle Cell Disease Nutrition Growth Puberty Guinea

Surgical Treatment of Upper Urinary Tract Lithiasis in Conakry

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Open Journal of Urology 2024年第9期14卷 487-498页

作者： Barry mamadou Madiou diallo thierno Oumar Sow thierno Amadou Oury diallo thierno mamadou Oury Bah Ibrahima Bah mamadou Diao Cissé Demba Bah Oumar Raphiou Service dUrologie Hpital National Ignace Deen Universit Gamal Abdel Nasser de Conakry Conakry Guinea

Introduction: The management of urinary lithiasis in our settings has long been conventional surgery. The recent introduction of endoscopy of the upper urinary tract represents a major advance in our department. The aim was to contribute to the study of the treatment of lithiasis of the upper urinary tract in Conakry and to report on our initial experience of ureteroscopy in Conakry. Methodology: This is a prospective descriptive study lasting one year, from January 1 to December 31, 2022, carried out at the Urology Department of the Ignace Deen National Hospital and at the PERCHIN Urological Clinic. The study included all patients treated surgically for lithiasis of the upper urinary tract who met the selection criteria. Results: The study included 57 patients. The mean age was 30 years, with extremes of 20 and 73 years;the most represented age group was 31 to 40 years, followed by 20 to 30 years with 29.9% and 26.3% respectively. Males predominated in 36 cases (63.15%), with a M/F sex ratio of 1.71. Left-sided renal colic was the most common, at 75.43% (n=43), and right-sided renal colic at 40.35%, associated with digestive signs at 43.85%. 77.19% had normal creatinine levels before surgery, versus 22.81% with elevated creatinine levels, i.e. 15.78% improvement in renal function after surgery. Urinary tract infection was found in 47.36%, and Escherichia coli in 31.57%, followed by staphylococcus aureus in 8.77%. Overall, 82.45% of patients had organic damage to the kidneys or ureters. Right ureterohydronephrosis was noted in 56.14%, followed by left hydronephrosis in 26.32%. Open surgery was predominant in 52.63% of cases, with endoscopic surgery (URS) accounting for a significant 47.36% during the study period. The endoscopic treatment used was laser ureteroscopy. In our study, 73.68% underwent drainage of the upper excretory tract, including 64.91% with a JJ catheter. The average length of stay was 07 days, with extremes of 02 and 28 days, and 81.4% of patients

关键词： Urinary Lithiasis Surgical Treatment Ureteroscopy Upper Urinary Tract Conakry

Profile of the Infertile Man at the University Hospital of Conakry (Guinea)

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Open Journal of Urology 2023年第7期13卷 223-237页

作者： Bah mamadou Bissiriou Kanté Daouda Sow thierno Amadou Oury thierno mamadou Oury diallo Koulalerou Aimon Axel Cédric Cissé Demba mamadou Diawo Bah Barry mamadou Dian thierno Oumar diallo diallo Alimou Ibrahima Bah Abdoulaye Bobo diallo Oumar Raphiou Bah Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Urology Department CHU of Conakry Guinea

Introduction: Male infertility is defined as the inability of a man to impregnate a woman after 12 months of regular sexual intercourse without contraception. Objective: To improve the state of knowledge on the profile of the infertile man in Guinea. Methodology: We conducted a prospective, descriptive study over a period of 6 months from October 1st, 2020 to March 31st, 2021. Results: We collected an overall number of 71 patients seen onroutine consultation for infertility. They had a mean age of 36.4 years. More than half of our patients were monogamous (79% of cases). Civil servants were the most affected with 38.02% of cases. Primary infertility was dominant in 65% (n = 46) of cases. On clinical examination, varicocele was the most remarkable abnormality with 88.73% (n = 63) followed by testicular hypotrophy with 59.15% (n = 42). Azoospermia was the most frequent sperm abnormality with 22.54% (n = 16) followed by oligospermia with 15.49% (n = 11). Hormonal assessment based on FSH and LH was performed in 16 patients with azoospermia (22.53%). FSH elevation was associated with azoospermia in 6 patients, i.e. 8.45%, azoospermia associated with a normal FSH level accounting for 14.08% in our series. Conclusion: In our practice, male infertility is becoming more and more of a concern due to the increasing number of patients seeking treatment. The scarcity of a medical assistance for procreation unit alongside with more efficient diagnostic means constitutes a handicap for its management.

关键词： Male Infertility Varicocele Azoospermia Spermogram

Role of Nrf2 in chronic liver disease

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World Journal of Gastroenterology 2014年第36期20卷 13079-13087页

作者： Wei Tang Yong-Fang Jiang Murugavel Ponnusamy mamadou diallo Liver Diseases Research Center The Second Xiangya Hospital Central South University Department of Medicine Rhode Island Hospital and Alpert Medical School of Brown University Providence RI 02903 United States Department of Immunology and Infectious Diseases Harvard School of Public Health Harvard UniversityBoston MA 02115-6018 United States

Nuclear erythroid 2-related factor 2(Nrf2) is a central regulator of antioxidative response elements-mediated gene expression. It has a significant role in adaptive responses to oxidative stress by interacting with the antioxidant response element, which induces the expression of a variety of downstream targets aimed at cytoprotection. Previous studies suggested oxidative stress and associated damage could represent a common link between different forms of diseases. Oxidative stress has been implicated in various liver diseases, including viral hepatitis, nonalcoholic fatty liver disease/steatohepatitis, alcoholic liver disease and drug-induced liver injury. Nrf2 activation is initiated by oxidative or electrophilic stress, and aids in the detoxification and elimination of potentially harmful exogenous chemicals and their metabolites. The expression of Nrf2 has been observed throughout human tissue, with high expression in detoxification organs, especially the liver. Thus, Nrf2 may serve as a major regulator of several cellular defense associated pathways by which hepatic cells combat oxidative stress. We review the relevant literature concerning the crucial role of Nrf2 and its signaling pathways against oxidative stress to protect hepatic cell from oxidative damage during development of common chronic liver diseases. We also review the use of Nrf2 as a therapeutic target to prevent and treat liver diseases.

关键词： Nuclear erythroid 2-related factor 2 Chronic liver disease Oxidative stress Reactive oxygen species Hepatic injury Hepatic protection

Urethrocystoscopy: Indications and Results in the Urology Department of the Ignace Deen National Hospital in Conakry

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Open Journal of Urology 2023年第8期13卷 302-308页

作者： diallo thierno mamadou Oury Bah mamadou Diawo Kanté Daouda Souaré mamadou Billo Cissé Demba Bah mamadou Bissiriou Barry Alpha Oumar diallo thierno Oumar diallo Alimou diallo Abdoulaye Bobo Bah Oumar Raphiou Urology Department Faculty of Health Sciences and Techniques of Conakry Ignace Deen National Hospital in Conakry Conakry Guinea

Introduction: Urethrocystoscopy is an examination of choice in the assessment of voiding disorders and especially macroscopic hematuria. The objective of this study was to analyze the indications and results of urethrocystoscopy in the urology department of the Ignace Deen National Hospital in Conakry. Material and Methods: We carried out a prospective descriptive study over 6 months, from 1st June to 30th November 2022, which included all patients who underwent urethrocystoscopy in the Urology Department of the Ignace Deen National Hospital in Conakry. We studied the following parameters: sex, age, indications and results of the examination, and complications. Results: 77 patients were included. The average age was 56.5 ± 19.5 years with extremes of [15 to 88 years]. The sex ratio was 2.9. Hematuria (50.7%) and lower urinary tract symptoms (32.4%) were the most frequent indications. Cystocystoscopy was normal in 14.3% of patients. Bladder tumors (29.9%) and prostatic hypertrophy (18.2%) were the most found lesions. Conclusion: Rigid urethrocystoscopy occupies an important place in the exploration of hematuria and lower urinary tract symptoms in our department. Bladder tumors and prostatic hypertrophy were the main lesions observed.

关键词： Urethrocystoscopy Hematuria Bladder Tumour