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中国科学院地质与地球物理研究所2013年度（第13届）学术年会

作者： Lin Chen Taras Gerya Zhongjie Zhang Guizhi Zhu thibault Duretz Wolfgang R.Jacoby State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of Sciences Institute of Geophysics Swiss Federal Institute of Technology(ETH Zurich) Institute of Geophysicsl Swiss Federal Institute of Technology(ETH Zurich) Institute fur Geowissenschafen Johannes Gutenberg-Universitt Mainz

The eastern Tibetan margin is characterized by a steep topographic gradient and remarkably lateral variations in crustal/lithospheric structure and thermal *** measurements show that the surface convergence rate in this area is strikingly *** can such a mountain range grow without significant upper crustal shortening? In order to investigate the formation mechanism of the eastern Tibetan-type margins, we conducted 2D numerical simulations based on finite difference and marker-in-cell *** numerical models were constrained with geological and geophysical observations in the eastern Tibetan margin. Several major parameters responsible for topography building,such as the convergence rate,the erosion/sediment rate,and the presence of partially molten crust,were systematically *** results indicate that the presence of partially molten material in the middle/lower crust can make a positive contribution to the formation of steep topography,but it is not a necessary factor.A steep topographic gradient may be a characteristic feature when a thin lithosphere with thick crust converges with a thick lithosphere with thin *** the context of a high erosion rate,the Longmen Shan range still gains and maintains its steep high topography to the *** could be explained by exerting a large push force on Tibet *** numerical experiments suggest that topographic characteristic across the eastern Tibetan-type margins is mainly derived from isostatic equilibration forces and intensive convergence between two continental lithospheres with totally different rheological properties.

关键词： Numerical modeling Eastern Tibetan margin Topography Lithospheric structure Partially molten crust

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采用闭环控制改善压铸机的性能

现代制造 2003年第27期 28-30页

作者： C.thibault M.Funke

使液压控制循环时间更快、产品质量更好、响应更高,是每一个流体动力控制系统追寻的目标。由MOOG公司设计的包括控制注射缸精确运动的伺服阀的注射液压回路子系统在实际应用中做到了这一点。

关键词：压铸机闭环控制液态金属铸件

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用粉状活性碳吸附法处理污水

国外农业环境保护 1992年第3期 42-45页

作者： G.T.thibault 刘宣智

用粉状活性碳吸附法(PACT)处理活性污泥,对于提高水质具有潜力,并且投资最少。水质和工艺过程的改善包括:更有效地去除有机物和氨,提高水质的稳定性和改善污泥的沉淀性能。用活性碳吸附法处理是改变活性污泥处理过程,目的在于改善工艺过... 详细信息

用粉状活性碳吸附法(PACT)处理活性污泥,对于提高水质具有潜力,并且投资最少。水质和工艺过程的改善包括:更有效地去除有机物和氨,提高水质的稳定性和改善污泥的沉淀性能。用活性碳吸附法处理是改变活性污泥处理过程,目的在于改善工艺过程,并无需增加投资。在工艺过程中,将粉状活性碳加入曝气池,在池内使之与生物固体混合,使碳维持在一定的水平,每天添加,以便补充污水和污泥中损失的碳量。

关键词：活性炭吸附法污水处理

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区块链与智能合约形成的共谋

竞争政策研究 2021年第1期 41-71页

作者： thibault Schrepel 时建中(译) 童肖安图(译) 乌得勒支大学法学院中国政法大学中国政法大学民商经济法学院

一、引言区块链可能会像互联网改变信息的传播与性质一样改变交易。2如果设想成真,那么公司之间的所有关系都会改变,包括被法律禁止的关系。因此,区块链引发的权益问题十分值得关注,3但致力于该问题的学术研究却严重缺乏,这一状况必须... 详细信息

一、引言区块链可能会像互联网改变信息的传播与性质一样改变交易。2如果设想成真,那么公司之间的所有关系都会改变,包括被法律禁止的关系。因此,区块链引发的权益问题十分值得关注,3但致力于该问题的学术研究却严重缺乏,这一状况必须得到改变。对该问题的相关研究必须尽快得到补充,因为随着技术的不断发展,法律在区块链中的适用也变得日趋复杂。因此,反托拉斯法与竞争法保持与时俱进是至关重要的,这些法律在规制技术所产生的力量及公司之间的互动方式上发挥了重要作用。本文旨在通过对区块链和共谋协议之间的相互作用进行研究,为反托拉斯法和竞争法的现代化作出贡献。

关键词：反托拉斯法区块链法的现代化智能合约互动方式竞争法互联网学术研究

Vitamin D in addition to peg-interferon-alpha/ribavirin in chronic hepatitis C virus infection: ANRS-HC25-VITAVIC study

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World Journal of Gastroenterology 2015年第18期21卷 5647-5653页

作者： Benjamin Terrier Nathanael Lapidus Stanislas Pol Lawrence Serfaty Vlad Ratziu Tarik Asselah Vincent thibault Jean-Claude Souberbielle Fabrice Carrat Patrice Cacoub Inflammation-ImmunopathologyBiotherapy Department (DHU i2B) Sorbonne Universités Department of Internal Medicine Groupe Hospitalier Cochin AP-HP Université Paris Descartes INSERM UMR_S 1136 Institut Pierre Louis d’Epidémiologie et de Santé Publique Sorbonne Universités UPMC Univ Paris 06 UMR_S 1136 Institut Pierre Louis d’ Epidémiologie et de Santé Publique Public Health Department Saint-Antoine Hospital Department of Hepatology Groupe Hospitalier Cochin AP-HP Université Paris Descartes Department of Hepatology H?pital SaintAntoine AP-HP Université Pierre et Marie Curie Department of Hepatology Groupe Hospitalier Pitié-Salpetrière AP-HP Université Pierre et Marie Curie Department of Hepatology H?pital Beaujon Department of Virology Groupe Hospitalier Pitié-Salpetrière AP-HP Université Pierre et Marie Curie Explorations Fonctionnelles H?pital Necker-Enfants Malades AP-HP Université Paris Descartes INSERM UMR_S 959 F-75013 Paris France CNRS UMR 7211 F-75005 Paris France Department of Internal Medicine and Clinical Immunology H?pital Pitié-Salpétrière AP-HP 47-83 boulevard de l’H?pital

AIM: To investigate if correction of hypovitaminosis D before initiation of Peg-interferon-alpha/ribavirin(Peg IFN/RBV) therapy could improve the efficacy of Peg IFN/RBV in previously null-responder patients with chronic genotype 1 or 4 hepatitis C virus(HCV) ***:Genotype 1 or 4 HCV-infected patients with null response to previous Peg IFN/RBV treatment and with hypovitaminosis D(received cholecalciferol 100000 IU per week for 4 wk[from week-4(W-4)to W0],followed by 100000 IUper month in combination with Peg IFN/RBV for 12 mo(from W0 to W48).The primary outcome was the rate of early virological response defined by an HCV RNAre included,19(59%)and 13(41%)patients were HCV genotype1 and 4,*** median baseline vitamin D level was 15 ng/m L(range:7-28).In modified intention-to-treat analysis,29 patients who received at least one dose of Peg IFN/RBV were included in the *** patients except one normalized their vitamin D serum *** rate of early virologic response was 0/29(0%).The rate of HCV RNAresponse in previously null-responders with chronic genotype 1or 4 HCV infection.

关键词： Vitamin D Hepatitis C virus Chronic hepatitis Pegylated interferon Ribavirin

脊髓灰质炎病毒特异性肠道抗体反应增强与婴儿肠道长双歧杆菌和短双歧杆菌的增多相一致:附一项随机、双盲、安慰剂对照试验

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世界核心医学期刊文摘（儿科学分册） 2005年第3期1卷 56-57页

作者： MulliéC. Yazourh A. thibault H. M.-B.Romond 阿明 Dr.Lab. de Bacteriologie-Virologie Fac.Sci. Pharmaceut./Biologiques Université de Lille 2 Rue du Pr Laguesse 59000 Lille France

为了明确肠道双歧杆菌数量是否会影响儿童对脊髓灰质炎病毒的免疫反应,笔者进行了一项随机的安慰剂对照试验。从出生到4月龄,给予婴儿服用发酵剂儿童配方(FIF)或标准配方(安慰剂)。每月测量儿童粪便中的双歧杆菌的数目。在接种前及第2... 详细信息

为了明确肠道双歧杆菌数量是否会影响儿童对脊髓灰质炎病毒的免疫反应,笔者进行了一项随机的安慰剂对照试验。从出生到4月龄,给予婴儿服用发酵剂儿童配方(FIF)或标准配方(安慰剂)。每月测量儿童粪便中的双歧杆菌的数目。在接种前及第2次疫苗注射后1 个月,对抗脊髓灰质炎病毒IgA抗体对Pentacoq的反应进行评价。共随机抽取30名儿童,有20名完成了研究(安慰剂组9名,FIF组11名)。FIF组中粪便双歧杆菌水平在4月龄时显著升高(P=0.0498)。而且FIF组婴儿在第4月龄时长双歧杆菌/婴儿双歧杆菌携带量较高(P=0.0399)。经过Pentacoq激发(P<0.001) 后,FIF组的抗脊髓灰质炎病毒IgA滴度显著升高(P< 0.02)。抗体滴度与双歧杆菌数目尤其与长双歧杆菌/ 婴儿双歧杆菌和短双歧杆菌数目(P<0.02)密切相关。体内寄生长双歧杆菌/婴儿双歧杆菌的婴儿同样显示具有较高的抗脊髓灰质炎病毒IgA水平(P< 0.02)。综上所述,目前的结果显示婴儿的抗脊髓灰质炎病毒反应能通过服用发酵配方所激发,该配方有利于肠道双歧杆菌生长。这种对免疫系统的作用是来源于配方中双歧杆菌(主要是长双歧杆菌/婴儿双歧杆菌和短双歧杆菌的激发)的作用还是牛奶发酵所产生的复合物(例如缩氨酸)的作用尚待研究。

关键词：脊髓灰质炎病毒疫苗注射抗体反应安慰剂对照免疫反应特异性抗体滴度体内寄生缩氨酸反应能

Atrial Fibrillation during Cerebral Infarction in Brazzaville: Frequency and Predictive Factors

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World Journal of Cardiovascular Diseases 2019年第12期9卷 891-898页

作者： Stéphane Méo Ikama Yann Luiz Ngouabi Ghislain Mpandzou Paul Macaire Ossou-Nguiet Jospin Makani thibault Gankama Christian Kouala-Landa Louis Igor Ondze-Kafata Bertrand Fikhaem Ellenga-Mbolla Thierry Raoul Gombet Suzy Gisèle Kimbally-Kaky Department of Cardiology Brazzaville University Hospital Center Brazzaville Congo Department of Neurology Brazzaville University Hospital Center Brazzaville Congo

In order to contribute to the improvement of brain infarction management in Brazzaville, a cross-sectional and analytical study with prospective data collection was conducted in the cardiology and neurology departments of the Brazzaville University Hospital, from February 1 to July 31, 2018. It included patients hospitalized for cerebral infarction confirmed with imaging, and having done an etiological assessment with at least one electrocardiogram at rest and one of long duration. Among these 138 patients included, 11 had atrial fibrillation, equaling?a frequency of 7.9%. The mean age of AF patients was 71 ± 8.8 years. The cardiovascular risk factors found were hypertension in eight cases (72.7%), diabetes in five cases (45.5%), abdominal obesity in four cases (36.4%). AF was permanent in 10 cases (91%), and paroxysmal in one case (9%). It was valvular in three cases (27.3%) and non-valvular in eight cases (72.7%). The cardiopathy involved was hypertensive in seven cases (63.6%), ischemic and valvular in two cases each. The CHA2DS2-VASc score, calculated in eight patients, was an average of 2.2, and ≥2 in more than 80% of patients;HAS-BLED score of 2.4 on average was ≥?3 in more than 72% of patients. Digoxin was prescribed in seven cases (63.6%) and an anti-vitamin K in eight cases (72.7%). In multivariate analysis, age (OR = 20.10, p = 0.023), arterial hypertension (OR = 23.82, p = 0.011), and dyslipidemia (OR = 2.03, p = 0.032) were the predictive factors found. AF is infrequent during brain infarction in Brazzaville. This systematic research raises the problem of age in our context.

关键词： Atrial Fibrillation Cerebral Infarction Frequency Predictive Factors Congo

Synchrotron Micro Tomography reveals 3D Shape of Precipitates in Cast Magnesium Alloy

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材料科学与工程（中英文版） 2011年第2期5卷 195-199页

作者： Klaus-Dieter Liss Xavier thibault Huijun Li Phil Bendeich Australian Nuclear Science and Technology Organisation New lllawarra Road Lucas Heights NSW-2234 Australia European Synchrotron Radiation Facility B P 220 F-38043 Grenoble Cedex France Faculty of Engineering University of Wollongong NSW-2522 Australia

Aim of the study is to compare the morphology of inclusions in magnesium alloy, investigated by both computed micro-tomography and light microscopy. Precipitates of denser material are found. The information of the light microscopic studies alone is by far insufficient to conclude on their three-dimensional shape. In contrast, the tomography reveals the full topology in all dimensions. The described inclusions are flake-like and can extend with high aspect ration into one, two or three dimensions.

关键词： Synchrotron radiation computed tomography light microscopy metallurgy magnesium

The Dynamics of Spreading of Oils on Hydrophilic and Hydrophobic Surfaces revisited Using Computational Fluid Dynamics

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材料科学与工程（中英文B版） 2013年第12期3卷 799-811页

作者： Badra Ali Talha Hocine Alia Somia Freifer thibault Roques-Carmes Laboratoire de Physique des Matdriaux Et des Fluides Universitd des Sciences et de la Technologic d'Oran BP 1505 ElM'Naouar Bir el Djir 31000 Oran Algeria Universite de Lorraine Laboratoire Reactions et Genie des Procedes UMR 7274 CNRS Nancy F-54000 France CNRS Laboratoire Reactions et Genie des Procedes UMR 7274 CNRS Nancy F-54000 France

The dynamics of drop spreading on horizontal smooth surfaces of different wettabilities is revisited using computational fluid dynamics (CFD). For this purpose, a recently developed CFD model, based on the volume of fluid technique (VOF), with piecewise linear interface calculations method (PLIC) for interface reconstruction, is generalized and applied to simulate the time evolution of spreading drops on solid surfaces (drop base radius and dynamic contact angle). The CFD simulations are quantitatively compared with previously published experimental results from other research groups. The influence of different factors, such as oils nature (silicone, mineral, peanut and coconut), viscosity (0.02-1 Pa·s), drop volume (0.3-38 μL) and type of surfaces (hydrophilic glass, stainless steel and hydrophobic glass) on the temporal evolution of the drop base radius and contact angle is investigated. For hydrophilic surfaces, the predictions of the CFD model agree remarkably well with the measurements. For hydrophobic surfaces, a small deviation between calculated and experimental results occurs because the model does not consider the partial slippage which can take place on hydrophobic materials. Despite neglecting this aspect, the simulations are found to capture the key features of drop spreading on hydrophobic surface. The fact that we obtain a good agreement between the proposed theory and the experimental results for a large range of oils and surfaces over five decades of time is a strong argument in favor of the model. The accuracy of the model demonstrates also that the influence of the surface wettabity (partial wetting and complete wetting) can be successfully simulated. The numerical results reproduce perfectly the spreading regimes which occur during the time course of the drop. The succession of two different regimes takes place in the following order: a hydrodynamic regime followed by a gravity regime.

关键词：计算流体动力学疏水表面传播机制亲水性 CFD模型 CFD模拟动态接触角疏水性材料