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Comparison of Three Experimental Models for Rat Osteoarthritis Induction

Journal of Biosciences and Medicines 2016年第12期4卷 62-69页

作者： Henrique Ribeiro Rodrigues-Neto Edilson Ferreira Andrade-Junior Denilson Jose Silva Feitosa-Junior André Lopes Valente thiago Cesar Xavier Bianca Caroline do Nascimento Alho Renan Kleber Costa Teixeira Fabio Vidal Moriya Rui Sérgio Monteiro de Barros Department of Orthopaedics and Traumatology Porto Dias Hospital Bel&eacute m Brazil Experimental Surgery Laboratory Par&aacute State University Bel&eacute m Brazil

Background: Osteoarthritis is a slowly progressive and debilitating disease with high prevalence in adult population. Knee is one of the joints most affected by this disorder. There are several models for animals’ osteoarthritis induction, however it is not identified any paper that compares these techniques. The present study was aimed to define the most appropriate model for rats osteoarthritis induction. Material and Methods: 40 Wistar rats were distributed into 4 groups of 10 animals each: normality group (NG);meniscectomy group (MG);quinolone group (QG) and iodoacetate group (IG). Radiographic images of the rat’s knees were analyzed as well as the amount of chondrocytes in the epiphyseal and articular cartilage. Results: In the radiographic analysis, there was a low correlation between the raters. Regarding the amount of chondrocytes in the epiphyseal cartilage, it was noticed that the IG and QG groups had fewer chondrocytes than NG, in contrast to MG that reported similar results to normality (p > 0.05). There was no significant difference between IG and QG groups (p > 0.05). Regarding the amount of chondrocytes in articular cartilage, it was noticed that the IG group showed fewer chondrocytes than NG (p 0.05). There was no significant difference between QG and MG groups (p > 0.05). Conclusion: Intraarticular injection of iodoacetate in rats is the model with greatest effect on reduction of chondrocytes amount.

关键词： Osteoarthritis Knee Joint Experimental Arthritis Animal Disease Models Rats

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Service Level Analysis Method-SLAM A framework for IT service organizations

Service Level Analysis Method-SLAM A framework for IT servic...

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2010 3rd IEEE International Conference on Computer Science and Information Technology—ICCSIT 2010

作者： Gianmario Motta Giovanni Pignatelli thiago Barroero Antonella Longo Department of Informatics & Systems University of Pavia Pavia Italy Innovation Engineering Department University of Salento Lecce Italy

We illustrate a conceptual framework for business oriented Service Level Management （SLM）. Currently IT systems are complex objects that support business operations. To be meaningful, a control system should link business and IT performances. This need, though recognized by most IT management frameworks, is not specifically analyzed. Defining a methodology capable to identify this link is the purpose of our work. The proposed methodology identifies relevant IT systems supporting business activities. The key novelty is that the integration between business Key Performance Indicators （KPIs） and IT systems KPIs is performed through a new uptake of Use Case approach. The paper illustrates the conceptual framework, the method and its use in a large transportation organization. The proposed approach has been successfully used by an organization.

关键词： component Service Level Management, IT Governance, Key performance Indicators

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NIKE CORRE： Generation Y Moves the Running Market

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Journal of Sports Science 2016年第5期4卷 300-310页

作者： thiago Simao Marcondes Reis Alessandra Morgado Ramiro de Lima Angelo Maia Cister Federal University of Rio de Janeiro Rio de janeiro 22290 240 Brazil

Focus on customer experience has proven to be one of the most important tools for the acceptance of the message of a brand by Millennials （Generation Y）. The aim of this study is to demonstrate how Generation Y influences, through their behavior and customs, the decisions to be made by the marketing area of companies. In this sense, the study seeks to demonstrate this situation by addressing the running market, which is consistently growing in Brazil and has unexplored niches, as in the case of a group of young runners who belong to Generation Y that called the attention of Nike＇s running segment, and was the focus of this research study. The case study was conducted by the qualitative method, based on an empirical investigation, in addition to a literature review. In this sense, it addressed the emergence of Generation Y, and how was the progress of the media that monitored it during this transition, going through multi-platform advertising. This approach is followed by a study of the running market and the role of Nike in it, how the project emerged and its relationship with Generation Y＇s behavior.

关键词： Generation Y running in Brazil marketing strategy consumer behavior studies Nike Corre.

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Splenectomy in Patient with Splendid Cysts

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Journal of Biosciences and Medicines 2018年第5期6卷 120-125页

作者： Viní cius Moreira Paladino thiago Sande Miguel Dé bora Trindade Martins Nayrton Kalys Cruz dos Anjos Fernando Antonio Galvã o Pereira Junior Marcia machado Galvã o Pereira Carolina Galvã o Teixeira Vinicius Sande Miguel Bruna Sande Miguel Daniel Almeida da Costa The Medical School at the Center of Higher Education of Valen& amp ccedil a Valen&amp amp ccedil a Brazil Suprema Medical School Juiz de Fora Brazil Universidade Grande Rio Medical School Rio de Janeiro Brazil

Introduction: Splenic cysts are uncommon and usually do not generate signs and symptoms, being diagnosed by incidental findings. Case report: A 35-year-old, female patient attended the Luiz Gioseffi Jannuzzi School Hospital (HELGJ) presenting episodes of vomiting and abdominal pain in the left hypochondrium. She was hospitalized for diagnostic investigation. Computed tomography showed the splenic cyst. The procedure was the surgical approach by laparotomy with splenectomy. Histopathological confirmed the diagnosis. Discussion: Compared to the scarce reports in literature, the case described presented typical epidemiology and clinical features. Conclusions: Given the rarity of this pathology cases, it is essential to report these in order to elucidate the specificities and also to discuss diagnostic and therapeutic methods.

关键词： Splenectomy Splendid Cysts Abdominal Pain

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Experimental Acoustic Determination of the Void Fraction in Two-Phase Flow in Horizontal Pipelines

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Journal of Mechanics Engineering and Automation 2014年第8期4卷 625-631页

作者： Fernando Augusto de Noronha Castro Pinto thiago de Campos Negrelly Alexandre Silva de Lima Mechanical Engineering Department UFRJ (Universidade Federal do Rio de Janeiro) Rio de Janeiro 21941-972 Brasil Mechanical Engineering Department CEFET/RJ (Centro Federal de Educag6o Tecnologica Celso Suckow da Fonseca) Rio deJaneiro 20271-110 Brasil

In multi-phase flows, the phases can flow and arranged in different spatial configurations in the pipe, which called flow patterns. This type of flow is found in the oil, chemical and nuclear industries. For example, in the production and transport of oil and gas, the identification of the flow patterns are essential for answering those questions which are related to the economic return of the field, such as, measuring the volumetric flow, determining the pressure drop along the flow lines, production management and supervision. In offshore production, these factors are very important. This paper presents a new method for measuring the void fraction in horizontal pipelines, taking the air as gas in water-air two-phase flow. Through acoustic analysis of the frequency response of the pipe, the method gets the parameters to changes in runoff regime, in an experimental arrangement constructed on a small scale. The main advantages are the non-intrusive characteristic and easy to implement. The paper is composed of a qualitative experimental evaluation and transducers （microphone） which are used to analyze variations in the response accompanying variations in void and flow pattern changes. Changes are imposed and controlled by a two-phase flow experimental simulation rig, including a measurement cell constituted of an external casing that can isolate the measurement from the environmental background noise fitted with acoustic pressure transducers radially arranged, and the impact of a monitored excitation mechanism. The signals which captured by the microphones are processed and analyzed by checking their frequency contents changes according to the amount of air in the mixture.

关键词： Experimental method two-phase flow determination of void fraction horizontal pipelines.

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The Role of CD4+ and CD8+ T-Cells during Angiostrongylus vasorum Infection in dogs

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Open Journal of Animal Sciences 2014年第5期4卷 285-290页

作者： Thales Augusto Barcante Lis Ribeiro do Valle Antonelli Kenneth Gollob thiago Pasqua Narciso Silvio Divino de Oliveira Junior Vitor Marcio Ribeiro Ricardo Toshio Fujiwara Ana Paula Peconick Debora Negrao-Correa Walter dos Santos Lima Joziana Muniz de Paiva Barcante Laboratorio de Biologia Parasitaria(BIOPAR) Departamento de Medicina VeterinariaSetor PreventivaUniversidade Federal de Lavras(UFLA)LavrasBrazil Instituto de Ciencias Biologicas Universidade Federal de Minas GeraisBelo HorizonteBrazil Programa de Pos-graduacao em Ciencias Veterinarias Departamento de Medicina VeterinariaUniversidade Federal de Lavras(UFLA)LavrasBrazil

A determinant factor in the pathology of canine angiostrongylosis seems to be related to the location of the parasite in the definitive host. Their presence inside the arteries and its branches, promoting mechanical and metabolic action on the wall of the vessels, may alter its homeostasis. Bronchoalveolar lavage (BAL) is a procedure that retrieves cells and other elements from de lungs for evaluation, and helps in the diagnosis of many pulmonary diseases. The aim of this study was to evaluate CD4+/CD8+ lymphocyte profile during the infection by Angiostrongylus vasorum, using cells retrieved using BAL. The identification of subpopulations of T lymphocytes by evaluating the co-expression of CD4 and CD8 receptor proteins has shown that despite the increase in both populations, there was a predominance of CD4+ T-cells, instead of CD8+ T-cells. These increases of CD4+ T-cells associated with the increase of the ratio between CD4+/CD8+ suggest polarization of a Th2 response. However, the immune cells, signaling factors, and cytokines that mediate such immunity and how and where they act within the body remain largely undefined during angiostrongylosis.

关键词： Citometria Angiostrongyliasis Brochoalveolar Lavage

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Root Canal Treatment Outcome and Restorative Condition of Teeth Treated by Undergraduates—A Clinical and Radiographic Evaluation

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Open Journal of Stomatology 2023年第9期13卷 257-270页

作者： Gabriela Tonet Bassani Bartelle Dianeia Miranda dos Reis thiago Oliveira Gamba Fabiana Vieira Vier-Pelisser School of Dentistry UCS—Caxias do Sul University Caxias do Sul Brazil School of Dentistry UFRGS—Federal University of Rio Grande do Sul Porto Alegre Brazil

Background: The aim was to evaluate the nonsurgical Root Canal Treatment (nRCT) outcome, the restorative condition and the relationship between the coronal restoration quality and the outcome of teeth endodontic treated by undergraduates at the University of Caxias do Sul School of Dentistry (UCS-SD), Brazil, between 2019 and 2021. Materials and Methods: Data from the endodontically treated cases were retrieved, and the patients were recalled for a follow-up appointment at the university. The endodontic diagnosis, radiographs, and the presence of definitive restorations were analyzed in the clinical records. During the follow-up appointment, endodontically treated teeth were classified as present or absent. The nRCT was classified as successful (complete or incomplete healing) or failure (uncertain or unsatisfactory healing). Coronal restoration was classified as absent or present. When it was present, it was classified as permanent or temporary, and its quality as adequate or inadequate restoration. The results were presented as percentages. Results: A total of 257 teeth were endodontically treated. The most prevalent diagnosis was Chronic Apical Periodontitis (33.33%) and the most commonly treated teeth were premolars (46.15%). A total of 52 (21%) treated teeth were clinically and radiographically reexamined. The success rate for the nRCT was 98.08%. About 61.54% of this sample had a definitive composite resin restoration. Conclusion: The nRCT success rate was high. Special attention should be given to the presence and quality of the definitive restoration. Clinical Implications: There was no statistically significant impact between the coronal restoration and the nRCT success (P > 0.05).

关键词： Periapical Periodontitis Permanent Dental Restoration Permanent Dental Filling Root Canal Obturation Treatment Outcome

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Postharvest Losses in the Wheat Logistics Chain： A Brazilian Case Study

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Journal of Agricultural Science and Technology(B) 2016年第5期6卷 321-329页

作者： Daniela Bacchi Bartholomeu Femando Vinlcius da Rocha thiago Guilherme Pera Jose Vicente Caixeta-Filho Research and Extension Group in Agroindustrial Logistics (ESALQ-LOG) University of Sao Paulo (USP) Piracicaba Sao PauloPostal Code 13418-900 Brazil

This paper highlighted the losses occurring along the wheat supply chain in Rio Grande do Sul （RS）, Brazil, which accounts for almost half of the domestic wheat production. Based on a field research, a questionnaire was applied to representative agents in the market. Then the wheat supply chain in the state of RS was characterized and loss rates in each stage of that chain were quantified. Typically, losses during transportation in the domestic market account for about 11.8% of the total amount of wheat grain that leaves the farms. Losses during harvest and storage in cooperatives, which account for 93.2% of total losses, stand out in this context. Transportation operations account for 6.8% of total losses in the analyzed flow. Based on the results obtained in this study, strategies are suggested to reduce food losses in different links of the logistics chain, such as to evidence and quantify the wheat losses, to manage losses and set reduction targets and to give attention to transportation service levels.

关键词： Postharvest losses wheat supply chain food security

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Tertiary peritonitis: A disease that should not be ignored

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World Journal of Clinical Cases 2021年第10期9卷 2160-2169页

作者： Hanna Santos Marques Glauber Rocha Lima Araújo Filipe Antônio França da Silva Breno Bittencourt de Brito Paulo Victor Dias Versiani Jaqueline Silva Caires thiago de Carvalho Milet Fabrício Freire de Melo Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900BahiaBrazil Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil Department of Surgery Hospital Geral de Vitória da ConquistaVitória da Conquista 45029-094BahiaBrazil

Intra-abdominal infections can be classified into uncomplicated or complicated(peritonitis). Peritonitis is divided into primary, secondary, and tertiary. Tertiaryperitonitis is the less common but the most severe among peritonitisstratifications, being defined as a recurrent intra-abdominal infection that occurs48 h after a well-succeeded control of a secondary peritonitis. This disease has acomplex pathogenesis that is closely related to the capacity of the peritonealcavity to activate immunological processes. Patients who progress to persistentperitonitis are at an increased risk of developing several infectious complicationssuch as sepsis and multiple organ failure syndrome. Moreover, tertiary peritonitisremains an important cause of hospital death mainly among patients withassociated risk factors. The microbiological profile of organisms causing tertiaryperitonitis is often different from that observed in other types of peritonitis. Inaddition, there is a high prevalence of multidrug-resistant pathogens causing thiscondition, and an appropriate and successful clinical management depends on anearly diagnosis, which can be made easier with the use of clinical scorespresenting a good prediction value during the intensive care unit ***, immediate therapy should be performed to control theinfectious focus and to prevent new recurrences. In this sense, the treatment isbased on initial antimicrobial therapy and well-performed peritoneal drainage.

关键词： Tertiary peritonitis Pathogenesis Clinical manifestation Diagnosis Treatment Prognosis

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Intense Exercise in the Quality of Life of Breast Cancer Survivors:A Meta-Analysis

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Journal of Cancer Therapy 2019年第12期10卷 895-907页

作者： Paulo Francisco de Almeida Neto Erenice Conceicao de Almeida Barbosa Karoline Queiroz Martins Almeida de Araujo Tatianny de Macedo Cesario Brunna Rafaella do Carmo Silva thiago Gil Vieira de Figueiredo Lima Nelson Carvas Junior Ana Carla Gomes Canario Federal University of Rio Grande do Norte UFRNNatalRNBrazil Brazilian Society of Clinical Oncology SBOCSao PauloSPBrazil Mauricio of Nassau University Center UNINASSANatalRNBrazil Institute of Medical Assistance to the state public servant IAMSPESao PauloSPBrazil Federal University of Paraíba UFPBJoao PessoaPBBrazil

The treatment of breast cancer (BC) leaves emotional and functional sequels affecting the quality of life (QOL) of the survivors. We aim to investigate, intense exercises in the rehabilitation of BC survivors. Using the systematic search model in the PubMed databases;Lilacs Bireme and Scielo. Meta-Analysis used the Meta package implemented in software R (version 3.3.2) p < 0.05. We selected 29 articles, and after reading in the Integra, we excluded 27 texts being included in the meta-analysis only 2. In the QOL, the heterogeneity in the emotional function showed a difference of 75%, in the social function 36% and in the physics 32%. Using intense exercises in BC survivors during rehabilitation improves overall QOL, muscle structure, and preserves functional capacity.

关键词： Breast Cancer High-Intensity Exercises High-Intensity Intermittent Exercise Women’s Health

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