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Height-to-diameter ratios with temporal and dendro/morphometric variables for Brazilian pine in south Brazil

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Journal of Forestry Research 2021年第1期32卷 191-202页

作者： Andre Felipe Hess Myrcia Minatti Emanuel Arnoni Costa luis Paulo Baldissera Schorr Gabriel Teixeira da Rosa Isadora de Arruda Souza Geedre Adriano Borsoi Veraldo Liesenberg thiago Floriani Stepka Roberta Abatti Department of Forest Engineering Santa Catarina State University2090 Luiz de Camoes AvenueLagesSanta Catarina State 88520-000Brazil Department of Forest Engineering Federal University of Parana(UFPR)Pref.Lothario Meissner Ave.900CuritibaParana 80060-000Brazil

Height-to-diameter ratios(HD)are an important measure of the stability,density and competition of forest *** refl ects the vertical growth of the trees,the vulnerability of the forest canopy structure and infl uences volumetric *** ratios vary according to tree size,availability of resources for growth,stand density and species *** were taken from 210 trees and a regression technique of generalized linear models for the HD ratio applicable for forest structure conservation was *** objective of this study was to model the HD ratios of dominant and co-dominant trees of Araucaria angustifolia according to morphometric,dendrometric,annual diameter increment,stand density,and age variables in three sites in southern *** results show that the HD ratio decreases with increasing age,crown area and basal area,and increases with stand density and annual diameter *** of the developed equations was demonstrated by the values of deviation,Bayesian and Akaike *** results are of interest to forest managers since they make decisions about silvicultural *** continuity and forest production indicate that any intervention should be directed at younger trees of smaller sizes,and that one of the main management factors for stand stability and growth is the formation of the stand and its capture of light.

关键词： Forest management Mixed forests Conservation Araucaria angustifolia

Corticosteroids for severe influenza pneumonia: A critical appraisal

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World Journal of Critical Care Medicine 2016年第1期5卷 89-95页

作者： Wagner luis Nedel David Garcia Nora Jorge Ibrain Figueira Salluh thiago Lisboa Pedro Póvoa Intensive Care Unit Hospital Nossa Senhora da Concei??o Intensive Care Unit Vila Franca de Xira Hospital D’or Institute for Research and Education Critical Care Department Hospital de Clinicas de Porto Alegre Post-Graduation Program (PPG) Pneumology Universidade Federal do Rio Grande do Sul Polyvalent Intensive Care Unit S?o Francisco Xavier Hospital Centro Hospitalar de Lisboa Ocidental Nova Medical School CEDOC New University of Lisbon

Influenza pneumonia is associated with high number of severe cases requiring hospital and intensive care unit(ICU) admissions with high mortality. Systemic steroids are proposed as a valid therapeutic option even though its effects are still controversial. Heterogeneity of published data regarding study design, population demographics, severity of illness, dosing, type and timing of corticosteroids administered constitute an important limitation for drawing robust conclusions. However, it is reasonable to admit that, as it was not found any advantage of corticosteroid therapy in so diverse conditions, such beneficial effects do not exist at all. Its administration is likely to increase overall mortality and such trend is consistent regardless of the quality as well as the sample size of studies. Moreover it was shown that corticosteroids might be associated with higher incidence of hospital-acquired pneumonia and longer duration of mechanical ventilation and ICU stay. Finally, it is reasonable to conclude that corticosteroids failed to demonstrate any beneficial effects in the treatment of patients with severe influenza infection. Thus its current use in s evere influenza pneumonia should be restricted to very selected cases and in the setting of clinical trials.

关键词： Influenza Mechanical ventilation Pneumonia Corticosteroids Respiratory failure

Integration of Tropical Renewable Energies

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Journal of Energy and Power Engineering 2019年第3期13卷 91-96页

作者： Daltro Garcia Pinatti Rosa Ana Conte thiago Hirosse Silva luis Miguel Paulo Rodolpho de Oliveira Moreira Department of Materials Engineering Lorena School of EngineeringUniversity of S鉶 PauloLorena 12602-810Brazil

Main sources of renewable energy in the tropics are solar thermal and ***-performance concrete(HPC)allows prefabrication of stakes,planks,boards,U-,L-,and I-profiles,prestressed thick-wall cylinders,and arc *** are used to construct fences,level curves,buildings,contention walls,water and anaerobic tanks,and *** production is increased by retention of rain water in the soil by level curves,in riparian tanks,and with *** anaerobic digesters produce biogas,biochar,and liquid *** is partially washed in medium-pressure vessel to obtain vehicular methane gas,which is partially burned in engine generator sets,whose combustion gases are fed into a boiler of a thermoelectric *** cycle is thermal solar regenerative Rankine cycle with heat *** receives hot water from thermal solar parabolic collectors,burns residual biomass and biochar generating steam for a turbogenerator set and combustion gas for condenser dryer silo,whose exhaustion heat goes to anaerobic digesters.

关键词： High-performance concrete profiles thermal solar-biomass energy generation biomass anaerobic digester biogas

Neglected tropical diseases risk correlates with poverty and early ecosystem destruction

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Infectious Diseases of Poverty 2023年第2期12卷 129-129页

作者： Arthur Ramalho Magalhães Cláudia Torres Codeço Jens-Christian Svenning luis E.Escobar Paige Van de Vuurst thiago Gonçalves-Souza Laboratory of Ecological Synthesis and Biodiversity Conservation (ECOFUN) Federal Rural University of Pernambuco Recife Brazil Scientific Computation Program (PROCC) Oswaldo Cruz Foundation (Fiocruz) Rio de Janeiro Brazil Center for Ecological Dynamics in a Novel Biosphere (ECONOVO) & Center for Biodiversity Dynamics in a Changing World (BIOCHANGE) Department of Biology. Aarhus University Aarhus Denmark Department of Fish and Wildlife Conservation Virginia Tech Blacksburg USA Center for Emerging Zoonotic and Arthropod-Borne Pathogens Virginia Tech Blacksburg USA Translational Biology Medicine and Health Program Virginia Tech Graduate School Blacksburg USA

Background Neglected tropical diseases affect the most vulnerable populations and cause chronic and debilitating *** vulnerability is a well-known and important determinant of neglected tropical *** example,poverty and sanitation could influence parasite ***,the quantitative impact of socioeconomic conditions on disease transmission risk remains poorly *** This study investigated the role of socioeconomic variables in the predictive capacity of risk models of neglected tropical zoonoses using a decade of epidemiological data(2007–2018)from ***-borne diseases investigated in this study included dengue,malaria,Chagas disease,leishmaniasis,and Brazilian spotted fever,while directly-transmitted zoonotic diseases included schistosomiasis,leptospirosis,and *** and socioeconomic predictors were combined with infectious disease data to build environmental and socioenvironmental sets of ecological niche models and their performances were *** Socioeconomic variables were found to be as important as environmental variables in influencing the estimated likelihood of disease transmission across large spatial *** combination of socioeconomic and environmental variables improved overall model accuracy(or predictive power)by 10%on average(P<0.01),reaching a maximum of 18%in the case of dengue *** domestic product was the most important socioeconomic variable(37%relative variable importance,all individual models exhibited P<0.00),showing a decreasing relationship with disease indicating poverty as a major factor for disease *** of natural vegetation cover between 2008 and 2018 was the most important environmental variable(42%relative variable importance,P<0.05)among environmental models,exhibiting a decreasing relationship with disease probability,showing that these diseases are especially prevalent in areas where natural ecosystem destruction is

关键词： Disease ecology Ecological niche model Socioecological system Vector-borne diseases Zoonosis Brazil

Scalp Melanoma Treated with Ipilimumab in Elderly Patient： A Complete Response to Treatment--Case Report

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Journal of Pharmacy and Pharmacology 2017年第1期5卷 1-4页

作者： Juliana Ramos Chaves Filipe Rocha da Silva Lucas Ivanilson Guedes Henriques Silva thiago Farias Camara luis Eduardo Wemeck de Carvalho Jonathan Souza Sarraf Oncologica Brasil--Education and Research Belem-PA 66053-000 Brazil Mecicine Faculty Universidade do Estado do Para Belem-PA 66087-670 Brazil Medicine Faculty Centro Universitario do Estado do Para Belem-PA 66613-903 Brazil Medicine Faculty Universidade Federal do Para Belem-PA 66075-110 Brazil

Melanoma is a malignant neoplasm that affects the melanocytes. Its treatment is based on cancer staging. In immunotherapy, it can be pointed out the ipilimumab, used in the systemic therapy for unresectable and/or metastatic melanoma in the first or the second line treatment with increased survival. However, limiting toxicity and the low complete response discourage its use in the elderly patients. The aim of this study is to report the case of an 83-year-old man, white, with scalp melanoma measuring 3.5 cm in its major axis. After two resections was verified that the deep margin was involved, making the lesions unresectable. The evaluation of distant metastasis, by skull, chest and abdomen CT-scan （computed tomography-scan）, was performed and did not detect the presence of any metastatic loci. The patient underwent the first cycle of chemotherapy with DTIC （dacarbazine） protocol. After the first cycle, the medication was discontinued due to significant myelotoxicity and Grade 3 thrombocytopenia. Underwent second line treatment with ipilimumab by four cycles. After this, the patient follow with complete local response, asymptomatic, with no signs of local recurrence or distant metastasis site, and no limiting toxicity during and after a year of treatment with ipilimumab. Thus, it is possible to suggest that the use of ipilimumab isolatedly as a second line treatment may have a good response even in elderly patients.

关键词： Scalp melanoma ipilimumab elderly patients.

Antimicrobial Susceptibility,Biofilm Production and Adhesion to HEp-2 Cells of Pseudomonas aeruginosa Strains Isolated from Clinical Samples

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Journal of Biomaterials and Nanobiotechnology 2013年第1期4卷 98-106页

作者： Alicia Valeria Zaranza Francyelle Costa Morais Monique Santos do Carmo Adriana de Mendonca Marques Cristina Andrade-Monteiro thiago Feitosa Ferro Valerio Monteiro-Neto Patricia de Maria Silva Figueiredo Research Center in Parasitic Diseases and Endemic University of CEUMAUniCEUMASao LuisBrazil

A hundred Pseudomonas aeruginosa strains from several clinical specimens from five hospitals in Sao Luís-MA were evaluated for biofilm production, prevalence of the gene algD, adhesion to HEp-2 cells and antimicrobial susceptibility. The most affected clinical specimens and hospital sectors were also evaluated. Most isolates were obtained from the tracheal aspirate (21.0%) and the most affected hospital sector was the ICU (43.0%). The antibiotics with the highest sensitivity rate were amikacin, piperacillin/tazobactam, fluoroquinolones, gentamicin and meropenem and the ones with the highest resistance rate were aztreonam, ceftazidime and cefepime. All samples were sensitive to polymyxin B. In relation to the expression of the gene for ESBL, 50.0% (17/34) of the multiresistant strains showed the enzyme TEM. Most strains showed high hydrophobicity and 96% of the isolates produced biofilm on a polystyrene microplate, 52% were capsule producers, 19% showed mannose-sensitive fimbriae and 39% expressed the gene algD. We observed adhesion to HEp-2 cells and to the coverslip. These factors may be reported in the pathogenesis of this bacterium, what represents a potential risk for colonization of medical devices which favor the establishment of chronic nosocomial infections.

关键词： Pseudomonas aeruginosa Antimicrobial Biofilm Adhesion

Evaluation of antibacterial and toxicological activities of essential oil of Ocimum gratissimum *** its major constituent eugenol

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Food Bioscience 2022年第6期50卷 2152-2159页

作者： Julio Cesar Silva Raimundo Luiz Silva Pereira thiago Sampaio de Freitas Janaína Esmeraldo Rocha Nair Silva Macedo Carla de Fatima Alves Nonato Marina Leite Linhares Daniely Sampaio Arruda Tavares Francisco Assis Bezerra da Cunha Henrique Douglas Melo Coutinho Sidney Gonçalo de Lima Francisco Nascimento Pereira-Junior Francisco Paulo Araújo Maia Ivo Cavalcante Pita Neto Fabiola Fernandes Galvão Rodrigues George Joaquim Garcia Santos Department of Biological Chemistry Regional University of CaririR.Cel.Antonio Luis 116163105000CratoCEBrazil University Center Doutor Leão Sampaio Av.Leão Sampaio 40063040000Juazeiro do NorteCEBrazil Research and Development Center for Medicines Federal University of CearaR.Coronel Nunes de Melo 100060430275FortalezaCEBrazil Chemistry Department Federal University of PiauiCampus Universitário Ministro Petrônio Portella64049550TeresinaPIBrazil Center for Agricultural and Biodiversity Sciences - CCAB Federal University of CaririCratoCearáBrazil CECAPE - College of Dentistry Juazeiro do NorteCE63024-015Brazil

The present study aimed to comparatively analyze the antibacterial activity,combined with antibiotics,and toxicological activity of the essential oil of *** *** its major compound,*** phytochemical analysis of the essential oil was performed by gas chromatography coupled with mass *** minimum inhibitory concentration and combined antibiotic activity were performed by *** melanogaster was the model organism chosen to evaluate the toxicological response of *** chromatographic assay showed eugenol as the major compound of the essential oil of *** *** microbiological assays showed that in terms of antibacterial activity,both products showed similar activity,quite significant in Gram-negatives,such as those of strains of Pseudomonas *** results were verified in the modulatory activity,allowing the verification that the bioactivity performed by the essential oil of *** *** mainly influenced by its major *** the EC50 of the compounds varied subtly,the essential oil was less toxic compared to *** information obtained in the present study demonstrates that the essential oil of *** *** a promising antibacterial agent and better tolerated than its majority compound alone,in the model organism ***.

关键词： Antibacterial agents Drosophila melanogaster Eugenol Ocimum gratisismumum L.essential oils

Characterization of Virulence Factors in Enteroaggregative and Atypical Enteropathogenic Escherichia coli Strains Isolated from Children with Diarrhea

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Advances in Infectious Diseases 2012年第4期2卷 135-142页

作者： thiago Azevedo Feitosa Ferro Francyelle Costa Moraes Andreia Meneses da Silva Claude Porcy Leandro Amorim Soares Cristina Andrade Monteiro Nyla Thyara Melo Lobao Francisco Amazonas Assis de Mello Valério Monteiro-Neto Patrícia de Maria Silva Figueiredo Research Group of Endemic and Parasitic Diseases CEUMA UniversitySao LuisBrazil Federal Institute of Maranhao Sao LuisBrazil Health and Biological Sciences Center Federal University of MaranhaoSao LuísBrazil

Enteroaggregative (EAEC) and atypical enteropathogenic (EPEC) Escherichia coli are important bacterial etiologic agents causing diarrhea among children. The aim of the present study was to examine the impact of virulence factors predisposes to diarrhea. In this study some virulence properties were examined on 11 EAEC and 8 EPEC strains identified by Polymerase Chain Reaction (PCR), isolated from stool samples of children were analyzed genotypically and phenoltypically for the prevalence of virulence factors. The most frequently detected factor was resistance to serum (94%), followed by curli fimbriae (78%), biofilm production (73%), and gene coding for Extended-Spectrum Beta-Lactamase (ESBL) (68%). EPEC isolates showed at least three of the evaluated properties, while EAEC isolates showed at least two. The prevalence of these virulence factors between the two strains showed no statistical difference. This study showed the heterogeneity of the virulence profile of the isolates of EAEC and atypical EPEC strains and suggests that this diversity may influence in the disease severity.

关键词： E.coli Diarrhea Virulence Factors

Chemical characterization UPLC-ESI-QToF-MSE,antibacterial and antibiofilm potential of Sarcomphalus joazeiro(MART.)Hauenschild

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Food Bioscience 2022年第6期50卷 1249-1259页

作者： Nara J.S.Araújo Ana Raquel P.Silva Maria S.Costa thiago S.Freitas José M.Barbosa Filho Yedda M.L.S.Matos Maria Flaviana B.Morais-Braga Francisco N.Pereira Junior C.A.P.Silva Erlânio O.Souza Paulo R.V.Ribeiro Bruna Caroline Gonçalves Vasconcelos de Lacerda Edlane Martins de Andrade Henrique D.M.Coutinho Jacqueline C.Andrade-Pinheiro Programa de pós-graduação em Ciências da Saúde Universidade Federal do CaririUFCADivino Salvador284CEP63180-000BarbalhaCEBrazil Programa de pós-graduação em Biotecnologia Universidade Estadual do CearáUECEAv.Dr Munguba1700CEP60714-903FortalezaCEBrazil Departamento de Química Biológica Universidade Regional do CaririURCACel Antônio Luis1161CEP63105-000CratoCEBrazil Laboratório de Tecnologia Farmacêutica Universidade Federal da ParaíbaUFPBCidade Universitária5009CEP58051-970João PessoaPBBrazil Laboratório de Bioensaios – LABIO Universidade Federal do Cariri – UFCAR.Olegário Emidio de Araujos/nCEP63260-000Brejo SantoCEBrazil Faculdade de Tecnologia do Cariri FATECAmália Xavier de OliveiroCEP63040-000Juazeiro do NorteCEBrazil Embrapa Agroindústria Tropical R.Pernambuco2270 - Pici60511-110FortalezaCEBrazil CECAPE College.Av.Padre Cícero 3917 - São JoséJuazeiro do NorteCE63024-015Brazil

The present study aims to demonstrate the chemical composition of the ethanolic extract of Sarcomphalus joazeiro bark and to evaluate its antibacterial and antibiofilm *** that,the ethanolic extract of the stem bark was prepared,and chemical characterization was carried out in *** inhibitory concentration and antibiotic modification test were performed by the microdilution *** and antiformation assays were evaluated by the crystal violet *** the chemical characterization,the presence of 24 peaks was *** activity showed minimum inhibitory concentration≥2048μg/*** the evaluations of the potentiating activity,synergism was the most *** the formation analysis,it was observed that most strains showed moderate biofilm *** was concluded that saponin derivatives are the major secondary metabolites in the analyzed extract and that it presents relevant synergism with the antibiotics studied and a significant ability to inhibit bacterial biofilm formation.

关键词： Biofilm Saponins Synergism Inhibition