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Transmission of severe acute respiratory syndrome coronavirus 2 via fecal-oral:Current knowledge

World Journal of Clinical Cases 2021年第28期9卷 8280-8294页

作者： Filipe Antônio França da Silva Breno Bittencourt de Brito Maria Luísa Cordeiro Santos Hanna Santos Marques Ronaldo Teixeira da Silva Júnior Lorena Sousa de Carvalho Samuel de Sousa Cruz Gabriel Reis Rocha Gabriel Lima Correa Santos Kathlen Coutinho de Souza Rebeca Gabrielle Almeida Maciel Daiana Silva lopes Natália oliveira e Silva Márcio Vasconcelos oliveira Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45002175BahiaBrazil departamento de Ciências Naturais Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45002175BahiaBrazil departamento de Bioquímica e Biofísica Universidade Federal da BahiaSalvador 40.110-100BahiaBrazil Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

The pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has resulted in more than 93 million cases and 2 million deaths in the ***-CoV-2 respiratory tract infection and its main clinical manifestations such as cough and shortness of breath are well known to the scientific ***,a growing number of studies have reported SARS-CoV-2-related gastrointestinal involvement based on clinical manifestations,such as diarrhea,nausea,vomiting,and abdominal pain as well as on the pathophysiological mechanisms associated with coronavirus disease ***,current evidence suggests SARS-CoV-2 transmission via the fecal-oral route and aerosol ***,studies have shown a high risk of contamination through hospital surfaces and personal ***,viable SARS-CoV-2 specimens can be obtained from aerosols,which raises the possibility of transmission through aerosolized viral particles from ***,the infection by SARS-CoV-2 via fecal-oral route or aerosolized particles should *** addition,a possible viral spread to sources of drinking water,sewage,and rivers as well as the possible risk of viral transmission in shared toilets become a major public health concern,especially in the least developed *** authors have emphasized the presence of viral RNA and even viable SARS-CoV-2 in human feces,studies on the possible fecal-oral coronavirus disease 2019 transmission become essential to understand better the dynamics of its transmission and,then,to reinforce preventive measures against this infection,leading to a more satisfactory control of the incidence of the infection.

关键词： COVID-19 SARS-CoV-2,Transmission Via fecal-oral

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On an Exact Cylindrically Symmetric Solution in a Born-Infeld Type Theory of Gravity

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Journal of High Energy Physics, Gravitation and Cosmology 2019年第3期5卷 711-718页

作者： Tiago de oliveira Rosa Maria Emilia Xavier Guimarã es Joaquim lopes Neto Instituto Federal Goiano Campus Uruta&#237 Rodovia Geraldo Silva Nascimento Uruta&#237 Brazil Instituto de Fí sica Universidade Federal Fluminense Niter&#243 i Brazil Instituto de Fí sica Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil

In this work, we derive an exact vacuum solution for a cylindrically symmetric metric in an extended gravity theory developed by Novello, de Lorenci and Luciane (hereafter referred to as the NDL theory) which is inspired in the Born-Infeld theory. The main goal of this paper is to nd a cosmic string solution for the NDL theory. However, a careful analysis of the metric shows that it is asymptotically singular and therefore does not represent a cosmic string solution.

关键词： Modi ed Theories of Gravity Topological defects

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The Control of Lactobacillus *** Extracellular Compound Produced by Pseudomonas aeruginosa in the Fermentation Process of Fuel Ethanol Industry in Brazil

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Journal of Sustainable Bioenergy Systems 2013年第3期3卷 194-201页

作者： Cintia Greice Matsuoca Gois Lucilene lopes-Santos Jamile Priscila de oliveira Beranger Admilton Goncalves de oliveira Flavia Regina Spago Galdino Andrade departamento de Microbiologia Laboratorio de Ecologia MicrobianaUniversidade Estadual de LondrinaLondrinaBrazil

This work evaluated the effect of secondary bacterial metabolites produced by Pseudomonas sp LV strain in control of Lactobacillus sp. population in the microcosm of the vat during ethanol fermentation. The fraction F4 produced by Pseudomonas aeruginosa was extracted with dichloromethane and fractionating by vacuum liquid chromatography obtained in a methanol phase. The evaluation of antibiotic activity of F4 fraction mixed or not with sulphuric acid and Kamoram?. The antibiotic activity of F4 fraction was determined as well as the fermentation efficiency. Also was determined yeast cell viability, budding formation, the viability of budding cells, and number of populations of Saccharomyces cerevisiae and Lactobacillus sp. The results showed that the F4 fraction had high selective antibiotic activity against Lactobacillus sp. but not for S. cerevisae, and no inhibitory effect was observed in the fermentation process by yeast. Also F4 fraction decreased flocculation and foam formation. The F4 has an antibiotic activity against Lactobacillus sp. and should be used as an alternative to control bacteria contamination and foam and flocculation formation in the fuel ethanol fermentation process. The F4 fraction could reduce the use of antibiotics in the control of Lactobacillus sp. population during the fuel ethanol production.

关键词： Fuel Ethanol Fermentation Contamination Lactobacillus Yeast Pseudomonas

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Productivity and Water-Use Efficiency of Sorghum in Rainfed Regime in the Semi-Arid Region of Brazil

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American Journal of Plant Sciences 2017年第9期8卷 2133-2148页

作者： Erialdo de oliveira Feitosa Antonio Flávio Batista Araújo Calorine Maria Bayma oliveira Fernando Bezerra lopes Eunice Maia de Andrade department Agricultural Engineering Federal University of Ceará Campus of Pici Fortaleza Brazil

Sorghum has become ever more prominent on the global energy scene, with studies in the area becoming extremely important. Agricultural production in the semi-arid region of the Brazilian Northeast is intrinsically dependent on rainfall in the region. However, on both inter- and intra-annual scales, the rainfall regime is quite irregular. The aim of this study was to evaluate the productivity of sorghum grown under a rainfed regime, and the water-use efficiency of crops in the semi-arid region of the northeast of Brazil. The work was carried out in the city of Tabuleiro do Norte in the semi-arid region of the State of Ceará. Mean productivity of the sorghum was 919.42 kg·ha-1, with maximum values being recorded for lot 02 (1032 kg·ha-1), lot 03 (1102 kg·ha-1), lot 04 (2143 kg·ha-1) and lot 12 (1367 kg·ha-1). The greatest value for water-use efficiency, 1.13 m3·kg-1, was found for lot 04, while the smallest value, 4.83 m3·kg-1 was seen in lot 02. It was found that the low productivity of sorghum in a rainfed regime shows that the lack of success in production systems in semi-arid regions is not due to the total amount of rainfall, but rather the spatial and temporal distribution of the rains, as well as the occurrence of hot, dry spells. Furthermore, it can be seen that the best ratio of grain production to water demand shows a strong correlation with the distribution of water throughout the cycle, and not only with the total volume.

关键词： Production Rainfed Agriculture Sorghum bicolor L.

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Assessing the relationship between the rumen microbiota and feed efficiency in Nellore steers

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Journal of Animal Science and Biotechnology 2021年第4期12卷 1645-1661页

作者： Déborah Romaskevis Gomes lopes Márcio de Souza Duarte Alex J.La Reau Ibrahim Zuniga Chaves Tiago Antônio de oliveira Mendes Edenio detmann Cláudia Braga Pereira Bento Maria Eugênia Zerlotti Mercadante Sarah Figueiredo Martins Bonilha Garret Suen Hilário Cuquetto Mantovani departamento de Microbiologia Universidade Federal de ViçosaViçosaMG 36570-900Brazil departamento de Zootecnia Universidade Federal de ViçosaViçosaMinas GeraisBrazil department of Bacteriology University of Wisconsin-MadisonMadisonWIUSA departamento de Bioquímia e Biologia Molecular Universidade Federal de ViçosaViçosaMinas GeraisBrazil Instituto de Zootecnia Centro APTA Bovinos de CorteSertãozinhoSão PauloBrazil

Background:Ruminants rely upon a complex community of microbes in their rumen to convert host-indigestible feed into ***,little is known about the association between the rumen microbiota and feed efficiency traits in Nellore(Bos indicus)cattle,a breed of major economic importance to the global beef ***,we compare the composition of the bacterial,archaeal and fungal communities in the rumen of Nellore steers with high and low feed efficiency(FE)phenotypes,as measured by residual feed intake(RFI).Results:The Firmicutes to Bacteroidetes ratio was significantly higher(Pdemonstrate that differences in the ruminal microbiota of high and low FE Nellore steers comprise specific taxa from the bacterial,archaeal and fungal *** OTUs belonging to the genus Piromyces were identified in animals showing high feed efficiency,whereas among archaea,Methanobrevibacter was associated with steers classified as *** identification of specific RFI-associated microorganisms in Nellore steers could guide further studies targeting the isolation and functional characterization

关键词： Beef cattle ITS1 region Next-generation sequencing RFI Rumen microbiota 16S rRNA gene

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Tree Crown Variation and Seasonal in the Phenolic Compounds Content of Stryphnodendron adstringens(Mart)Coville Leaves

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American Journal of Plant Sciences 2014年第19期5卷 2904-2912页

作者： Alessandra de oliveira Ribeiro Selma lopes Goulart Fábio Akira Mori Ana Hortencia Fonseca Castro department of Forest Sciences Federal University of LavrasCampus UniversitárioLavrasBrazil Pharmacy department Natural Products LaboratoryFederal University of Sao Joao Del ReiDivinopolisBrazil

The aim of this study was to compare phenolic compounds contents between different positions within the crown and between collection periods, and to evaluate the tannin contents by the Folin-Ciocalteu method. The collections were performed in Lavras, in the southern region of the Brazilian state Minas Gerais. The experiment was conducted in a completely randomized design (factorial 3 × 4);the first factor being the position (base, middle, top);and the months, the second factor (February, May, September and december). We verified that the leaves of S. adstringens present higher total phenolic and tannin contents at the top (23.05% and 18.23%) and base (21.42% and 16.61%) of the crown, in May (25.79% and 20.85%) and September (25.57% and 20.50%), respectively. There was no difference in the residual phenol and flavonoid contents between the positions within the crown or in the months of collection. These facts suggest that within the crown and climatic changes may be one of the factors affecting phenol levels in Stryphnodendron adstringens.

关键词： Barbatimao Tannins Leaves Seasonal Variation Cerrado

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Perceived Efficacy of Vaginal Dryness Relief: A Comparative Clinical Study between Sodium hyaluronate vaginal gel1vs. Promestriene cream2

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Advances in Sexual Medicine 2017年第1期7卷 34-43页

作者： Eduardo de oliveira Duque-Estrada Vivian Pessoto Rosa Mariane Martins Mosca Heliara lopes do Nascimento Hospital Municipal Dr. Moysés deutsch S&atilde o Paulo Brazil Allergisa CRO Team S&atilde o Paulo Brazil

In the study, we report the comparative efficacy of the sodium hyaluronate gel vaginal application and promestriene cream which were tested to treat the gynecological symptoms of people who suffered from vaginal dryness. Method: 35 patients applied sodium hyaluronate vaginal gel one time a day for a period of two times a week during three weeks and other 33 patients using promestriene cream applied it every day for a period of three weeks also. Results: No significant difference was observed between vaginal application of sodium hyaluronate gel and promestriene cream, regarding both, as regarding the dryness of the intimate mucosa (p = 0.786), the attribute of moisturizing properties to the intimate mucosa (p = 0.142), the comfort sensation (p = 0.528), and no significant difference was observed regarding the fragrance of the product (p = 0.088). Conclusion: The similar results between vaginal application of both products support the use of sodium hyaluronate vaginal gel (Lubrinat®) in the initial approach of symptoms of vaginal dryness.

关键词： Vaginal Dryness Menopause Sodium Hyaluronate Promestriene

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On the Jebsen-Birkhoff Theorem in a Born-Infeld Type Theory of Gravity

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Journal of High Energy Physics, Gravitation and Cosmology 2019年第4期5卷 1051-1056页

作者： Tiago de oliveira Rosa Maria Emilia Xavier Guimar&atilde es Rocco Pascale Neto Joaquim lopes Neto Instituto Federal Goiano Campus Urutaí Rodovia Geraldo Silva Nascimento Urutaí Brazil Instituto de Física Universidade Federal Fluminense Niterói Brazil Instituto de Física Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil

In this paper we work with a special theory of gravity|the Novello-Di Lorenci-Luciane (hereby called NDL theory) which extends the Feynman-deser standard theoretical-fi eld approach to General Relativity. In the so-called NDL theory, matter interacts universally with gravity in accordance with the Weak Equivalence Principle, while gravitons have a nonlinear self-interaction. Our main aim in this work is to show that, though the NDL theory does not admit a Schwarzschild solution, the Jebsen-Birkhoff theorem is still valid in this framework.

关键词： Electrostatic Trapping Bootstrap Current Mitigation Peeling-Ballooning Mode

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A Reliability-Based Strategy for the Analysis of Single Proton Exchange Membrane Fuel Cells

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Energy and Power Engineering 2019年第8期11卷 303-319页

作者： Patricia da Silva Pagetti de oliveira Vinicius Andrea Elisabete Inacio Santiago Thiago lopes delvonei Alves de Andrade Marcelo Linardi Nuclear and Energy Research Institute IPEN-CNEN/SP S&atilde o Paulo Brazil

The development of power conversion systems based on fuel cells has been demanding reliability studies since the requirements associated with cost and durability of these technological products have become fundamental to their acceptance by the energy market. The experimental part of the reliability study presented in this work consisted of performing life tests with single proton exchange membrane fuel cells (PEMFCs). The proposed reliability analysis methodology covered the application of qualitative and quantitative techniques. In the qualitative approach, a Failure Mode and Effect Analysis was developed in order to identify and evaluate all potential failures associated with the operation of fuel cells. In the quantitative approach, a statistical analysis was applied to the sample data generated in long-term steady-state tests of these devices. A two-parameter exponential distribution was fitted to data and the maximum likelihood estimate for the mean time to failure (MTTF) of the fuel cells was calculated. It is important to point out that the tests performed under the scope of this study were the first long-term experiments performed with the fuel cells produced in the laboratories of IPEN-CNEN/SP, Brazil. Although the results indicated that fuel cell performance and durability were still at a level below the targets normally established for similar commercial devices, the improvement of the main components of PEMFCs has been the objective of several projects developed at the institute. Thus, the main benefit brought by this study is the proposed methodology, which can be implemented as part of a reliability growth analysis of the fuel cells and can be integrated into the design process of these devices.

关键词： Fuel Cells Reliability Durability Performance Life Tests Lifetime Failure-Time

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Proton nuclear magnetic resonance-based metabonomic models for non-invasive diagnosis of liver fibrosis in chronic hepatitis C:Optimizing the classification of intermediate fibrosis

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World Journal of Hepatology 2018年第1期10卷 105-115页

作者： Andrea Dória Batista Carlos Jonnatan Pimentel Barros Tássia Brena Barroso Carneiro Costa Michele Maria Goncalves de Godoy Ronaldo Dionísio Silva Joelma Carvalho Santos Mariana Montenegro de Melo Lira Norma ThoméJucá Edmundo Pessoa de Almeida lopes Ricardo oliveira Silva Postgraduate Program in Tropical Medicine Center for Health SciencesUniversidade Federal de PernambucoRecifePernambuco 50670-901Brazil department of Gastroenterology and Hepatology Hospital das ClínicasUniversidade Federal de PernambucoRecifePernambuco 50670-901Brazil department of Fundamental Chemistry Center for Exact and Nature SciencesUniversidade Federal de PernambucoRecifePernambuco 50670-901Brazil Intensive Care Unit Hospital das ClínicasUniversidade Federal de PernambucoRecifePernambuco 50670-901Brazil department of Pathology Hospital das ClínicasUniversidade Federal de PernambucoRecifePernambuco 50670-901Brazi

AIM To develop metabonomic models(MMs), using 1 H nuclear magnetic resonance(NMR) spectra of serum, to predict significant liver fibrosis(SF: Metavir ≥ F2), advanced liver fibrosis(AF: METAVIR ≥ F3) and cirrhosis(C: METAVIR = F4 or clinical cirrhosis) in chronic hepatitis C(CHC) patients. Additionally, to compare the accuracy of the MMs with the aspartate aminotransferase to platelet ratio index(APRI) and fibrosis index based on four factors(FIB-4). METHODS Sixty-nine patients who had undergone biopsy in the previous 12 mo or had clinical cirrhosis were included. The presence of any other liver disease was a criterion for exclusion. The MMs, constructed using partial least squares discriminant analysis and linear discriminant analysis formalisms, were tested by cross-validation, considering SF, AF and C. RESULTS Results showed that forty-two patients(61%) presented SF, 28(40%) AF and 18(26%) C. The MMs showed sensitivity and specificity of 97.6% and 92.6% to predict SF; 96.4% and 95.1% to predict AF; and 100% and 98.0% to predict C. Besides that, the MMs correctly classified all 27(39.7%) and 25(38.8%) patients with intermediate values of APRI and FIB-4, respectively. CONCLUSION The metabonomic strategy performed excellently in predicting significant and advanced liver fibrosis in CHC patients, including those in the gray zone of APRI and FIB-4, which may contribute to reducing the need for these patients to undergo liver biopsy.

关键词： Metabolomics Nuclear magnetic resonance spectroscopy Chronic hepatitis C Liver fibrosis Surrogate markers

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