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chinese clinical practice guidelines for ultrasound-guided irreversible electroporation of liver cancer(version 2022)

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Hepatobiliary & Pancreatic Diseases International 2022年第5期21卷 462-471页

作者： Min Xu Li-Ting Xie Yue-Yong Xiao Ping Liang Qi-Yu Zhao Zhong-Min Wang Wei-Lu Chai Ying-Tian Wei Lin-Feng Xu Xiao-Kun Hu Ming Kuang Li-Zhi Niu Chen-Guo Yao Hai-Ying Kong Guo Tian Xiao-Yan Xie Xin-Wu Cui Dong Xu Jun Zhao Tian-An Jiang the interventional diagnosis and treatment group of the ultrasonic medicine branch of chinese medical association,the nanoknife tumor ablation society of the interventional minimally invasive therapy special committee of china medicine education association Department of Ultrasound medicine First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Key Laboratory of Pulsed Power Translational medicine of Zhejiang Province HangzhouZhejiang 310003China Department of Radiology The First Medical CenterChinese PLA General HospitalBeijing 100000China Department of Radiology The Fifth Medical CenterChinese PLA General HospitalBeijing 100853China Department of interventional Radiology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Department of interventional Radiology Sun Yat-Sen Memorial HospitalSun Yat-Sen UniversityGuangzhou 510120China Department of the interventional medical Center the Affiliated Hospital of Qingdao UniversityQingdao 266000China Division of interventional Ultrasound The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080China Department of Oncology Affiliated Fuda Cancer HospitalJinan UniversityGuangzhou 510665China School of Electrical Engineering Chongqing UniversityChongqing 400033China Department of Anesthesiology First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of medical ultrasonics Institute of Diagnostic and Interventional UltrasoundThe First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080China Department of medical Ultrasound Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of interventional Ultrasound The Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital)Institute of Basic Medicine and Cancer(IBMC)Chinese Academy of SciencesHangzhou 310022China Department of Anatomy School of Basic MedicineHuazhong University of Science and TechnologyWuhan 430030China 不详

Introduction Liver cancer remains a global health challenge,and its incidence is increasing *** is estimated that by 2025,more than one million individuals will be affected by liver cancer annually[1,2].In recent years,ablation has become a widely accepted treatment option for patients with primary and secondary liver malignancies[3].The commonly used ablation method for liver cancer is thermal ablation,including radiofrequency ablation.

关键词： cancer liver Liver

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chinese expert consensus on refined diagnosis, treatment, and management of advanced primary liver cancer (2023 edition)

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Liver Research 2024年第2期8卷 61-71页

作者： Xiufeng Liu Feng Xia Yue Chen Huichuan Sun Zhengqiang Yang Bo Chen Ming Zhao Xinyu Bi Tao Peng Aizier Ainiwaer Zhiwen Luo Fusheng Wang Yinying Lu Department of medical Oncology Bayi Hospital Affiliated to Nanjing Chinese Medical University Nanjing Jiangsu China Department of Hepatobiliary Surgery Southwest Hospital Army Medical University Chongqing China Senior Department of Hepatology The Fifth Medical Center of PLA General Hospital Beijing China Department of Liver Surgery and Transplantation Liver Cancer Institute Zhongshan Hospital Fudan University Shanghai China Department of interventional therapy National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of minimally invasive interventional therapy Liver Cancer Study and Service Group Sun Yat-sen University Cancer Center Guangzhou Guangdong China Department of Hepatobiliary Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Hepatobiliary Surgery The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China Senior Department of Infectious Diseases The Fifth Medical Center of PLA General Hospital Beijing China Comprehensive Liver Cancer Center The Fifth Medical Center of PLA General Hospital Beijing China

Hepatocellular carcinoma (HCC), commonly known as primary liver cancer, is a major cause of malignant tumors and cancer-related deaths in china, accounting for approximately 85% of all cancer cases in the country. Several guidelines have been used to diagnose and treat liver cancer. However, these guidelines provide a broad definition for classifying advanced liver cancer, with an emphasis on a singular approach, without considering treatment options for individual patients. Therefore, it is necessary to establish a comprehensive and practical expert consensus, specifically for china, to enhance the diagnosis and treatment of HCC using the Delphi method. The classification criteria were refined for chinese patients with HCC, and the corresponding optimal treatment regimen recommendations were developed. These recommendations took into account various factors, including tumor characteristics, vascular tumor thrombus grade, distant metastasis, liver function status, portal hypertension, and the hepatitis B virus replication status of patients with primary HCC, along with treatment prognosis. The findings and recommendations provide detailed, scientific, and reasonable individualized diagnosis and treatment strategies for clinicians.

关键词： Hepatocellular carcinoma (HCC) Targeted therapy Immunotherapy Refined diagnosis and treatment Expert consensus

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超声引导肝癌不可逆电穿孔消融治疗临床实践指南(2023版)

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中华超声影像学杂志 2023年第12期32卷 1013-1020页

作者：中华医学会超声医学分会介入诊疗学组中国医药教育协会介入微创治疗专委会纳米刀肿瘤消融学会蒋天安许敏谢丽婷柴玮璐孔海莹田果不详浙江大学医学院附属第一医院超声医学科杭州310003 浙江大学医学院附属第一医院

目前我国肝癌发病率位居恶性肿瘤第4位,死亡率位居第2位,严重威胁人民的生命健康[1]。尽管手术切除是肝癌首选的治疗方法,但因大部分患者合并肝硬化或在确诊时已达中晚期,仅20%~30%的患者能获得手术切除的机会[2]。近年来,局部消融治疗... 详细信息

目前我国肝癌发病率位居恶性肿瘤第4位,死亡率位居第2位,严重威胁人民的生命健康[1]。尽管手术切除是肝癌首选的治疗方法,但因大部分患者合并肝硬化或在确诊时已达中晚期,仅20%~30%的患者能获得手术切除的机会[2]。近年来,局部消融治疗得到广泛应用,凭借微创、局部疗效确切和禁忌证少等优势,使许多不能或不耐受手术的患者得到有效治疗[3]。目前肝癌常用的局部消融方法为热消融,包括射频、微波和激光等。尽管上述方法各具优势,但难以避免消融过程中产生的热量,在杀伤肿瘤的同时损伤消融区域内的管道系统和神经等重要组织,造成严重并发症,并且因血液循环会引起"热沉效应",使得热消融在邻近血管或胆管的肝癌中应用受限[4,5]。

关键词：肝癌发病率消融治疗热消融合并肝硬化临床实践指南耐受手术血液循环禁忌证

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