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武汉市631名学龄前儿童龋病发病情况调查

湖北医学院学报 1988年第2期 147-150页

作者：汤爱明湖北医学院附二医院口腔科

631名武汉市某保育院学龄前儿童龋病发病情况调查结果表明:龋患率(74.3％)及龋均较过去有大幅度的升高,应引起重视。另外对患龋齿位、龋齿的好发部位、龋损程度以及治疗措施进行了阐述。

关键词：龋齿/预防和控制龋齿/治疗儿童

Clinical Trial of Cancer Therapy with Heavy Ions at Heavy Ion Research Facility in Lanzhou （HIRFL）

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Clinical Trial of Cancer Therapy with Heavy Ions at Heavy Io...

A Research of Longo procedure(PPH) in the Management Of outlet obstructed constipation(60 cases report)

第14届国际自由基学术大会

作者： Hong Zhang 1 2 Sha Li3 Xiaohu Wang 4 Qiang Li1 2 Shihua Wei3 Liying Gao4 Weiping Zhao1 2 Zhengguo Hu1 Ruishi Mao1 Hushan Xu1 Juntao Ran 4 Yangjun Yue3 Guoqing Xiao1 1 Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000 China 2 Key Laboratory of Heavy Ion Radiation Medicine of Gansu Province Lanzhou 730000 China 3 The General hospital of Lanzhou Command Lanzhou 730050 China 4 Tumor hospital of Gansu Province Lanzhou 730050 China

＜正＞From November 2006 to March 2008, 66 patients with superficially-placed tumors were treated with carbon ions at Heavy Ion Research Facility in Lanzhou （HIRFL） within six beam time blocks of 4-11 days, collaborating with the General hospital of Lanzhou Command and the Tumor hospital of Gansu Province. Patients and Methods

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A Research of Longo procedure(PPH) in the Management Of outl...

北京结直肠肛门病学术交流会暨卢克捷学术思想研讨会

作者： Beijing Coloproctological hospital Beijing erlonglu hospital,Beijing,P.R.China Duan hongyan

Objective:To evaluate the application of Longo’s procedure(procedure for prolapse and hemorrhoids,PPH)in the patients of constipation(OOC).Methods:60 cases of outlet obstructed constipation(rectal mucosal prolapse 45 cases,rectal mucosal prolapse with rectocele 10 cases, rectocele 5 cases respectively)were treated by ***:58 cases could empty bowls smoothly post-operation with once PPH ***:PPH is effective for the patients of outlet obstructed constipation resulting from rectal mucosal prolapse or/and rectocele.

关键词： PPH Outlet Obstructed Constipation(OOC) Operation

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我国医院信息系统必走整合之路

中华医学图书情报杂志 2004年第2期13卷 54-55页

作者：尚武杨涌武汉大学人民医院图书馆湖北武汉430060

论述了我国医院信息系统(HIS)整合的重要意义和原则,介绍了HIS整合的方法措施以及经验。

关键词：中国医院信息系统 HIS 医院管理标准化

Co-culture with cardiomyocytes induces mesenchymal stem cells to differentiate into cardiomyocyte-like cells and express heart development-associated genes

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Co-culture with cardiomyocytes induces mesenchymal stem cell...

Vitrectomy for Complicated Eales Disease

第一届全国中西医结合心血管病中青年医师论坛

作者： Junyi Zeng~1 Yang Wang~2 Yunfeng Wei~1 An Xie~2 Yuanlei Lou~2 Mei Zhang~1 1 Department of Cardiology, 2 Institute of Urological Surgery,the First affiliated hospital of Nanchang University,NanChang 330006

Recent studies have demonstrated that bone marrow mesenchymal stem cells(MSCs)have the potential to transdifferentiate into cardiomyocytes(CMs)in an appropriate condition both in vivo and in vitro,and our previous studies also confirmed ***,there exists a controversy among a variety of studies about whether MSCs can differentiate into CMs without physical contacts with CMs,and the mo- lecular signals that underlie this process are not fully *** the present study,MSCs isolated from adult rats were cocuhured with CMs obtained from neonatal rat ventricles at 1:5 ratio in a dual chamber dish separated by a semipermeable membrane for 2 *** this non-direct contact cocuhure procedure,cardiomyogenic differentiation and relative genes expression in MSCs were evalua- *** coculture with CMs,MSCs showed a stick-like or elliptical morphology,lmmunofluorescent stain results revealed that α-aetin and cardiac troponin T(cTnT)positive cells were found in MSCs at 5 days after cocuhure with CMs,and 29.63% of MSCs were positive for α-actin and 27.38% for cTnT at 14 *** from RT-PCR demonstrated the expression level of TGF-β,Nkx-2.5,GATA-4 and MEF-2C genes began to increase at 1 day and reached the peak at 7 days after *** conclu- sion,non-direct contact with CMs(1:5)is conducive for MSCs to differentiate into CMs in vitro,and TGF-β,Nkx-2.5,GATA-4 and MEF-2C genes may play a crucial role during the transdifferentia- tion.

关键词： bone marrow mesenchymal stem cells non-direct contact differentiation genes cardiomyocytes

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眼科学报 1997年第1期13卷 25-28页

作者： Yannian Hui,Lin Wang,Xiaoyan CaoDepartment of Ophthalmology, Xijing hospital, 4th Military Medical University, Xian 710032 , China Department of Ophthalmology Xijing Hospital 4th Military Medical University Xian 710032 China.

Purpose: We determined the efficacy of pars plana vitrectomy in a series of patients with complicated Eales ***: Clinical records were reviewed on 47 consecutive patients (49 eyes) who underwent vitrectomy for persistent vitreous hemorrhage (PVH) and/or traction retinal detachment (Trd) with neovascular membranes (NVM). All cases were divided into 4 subgroups of eyes with PVH (without obvious NVM, n = 9), NVD (NVM from the optic disc, n = 10), NVP (peripheral NVM, n = 11), or ENV (extensive NVM and logn-standing Trd,n- 17).Results: The study included 8 women and 39 men with a mean age of 27. 3 years (range, 16 to 50 years). The visual acuity was light perception in 15 eyes, hand motions in 18 eyes, counting fingers in 6 eyes and 0. 02 to 0. 1 in 10 eyes before vitrectomy. Visual acuity improved postoperatively in all eyes with PVH, NVD of NVP with a mean visual acuity of 0. 32 (range,0. 05 to 1. 0,n = 28) except 3 eyes unchanged There was no significant difference ( P > 0. 05 ) in the

关键词：眼病玻璃体切除术视觉预后视网膜剥离玻璃体出血新血管形成膜

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血管性头痛患者脑血管TCD改变

沈阳医学院学报 1996年第4期 28-29页

作者：由子佳何萍沈阳医学院附属二院神经内科沈阳医学院附属二院血管无创检查室

对164例血管性头痛患者进行了经颅多普勒颅内主要动脉平均血流速度测定。结果显示血管性头痛患者的平均血流速度明显高于正常人。提示血管性头痛与颅内动脉的痉挛密切相关。

关键词：血管性头痛经颅多普勒

虫草菌丝对实验性肝硬化大鼠肝组织胰岛素酶活性的影响

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中国新药与临床杂志 2003年第10期22卷 602-605页

作者：张霞吴小翎刘玉侃沈薇沈鼎明重庆医科大学附属第二医院消化内科重庆400010

目的 :探讨虫草菌丝对实验性肝硬化大鼠肝组织匀浆上清液胰岛素酶活性的动态影响及其可能机制。方法 :以CCl4诱导大鼠肝硬化模型 ,设立正常组、模型组和虫草组。正常组于实验开始时便处死大鼠 ,而后 2组则于造模 3 ,6,9wk分批处死 ,取... 详细信息

目的 :探讨虫草菌丝对实验性肝硬化大鼠肝组织匀浆上清液胰岛素酶活性的动态影响及其可能机制。方法 :以CCl4诱导大鼠肝硬化模型 ,设立正常组、模型组和虫草组。正常组于实验开始时便处死大鼠 ,而后 2组则于造模 3 ,6,9wk分批处死 ,取血及肝组织标本。生化法测定血清丙氨酸转氨酶(ALT)、清蛋白 (ALB)含量 ,放射免疫法测定血清透明质酸 (HA)、血清胰岛素 (INS)含量及肝组织匀浆上清液的胰岛素酶活性。结果 :(1 ) 3 ,6wk虫草组大鼠血清ALT ,ALB及HA含量与对应模型组差异无显著意义 (P >0 .0 5 ) ,9wk虫草组大鼠血清ALT ,HA含量显著低于对应模型组 (P 3wk虫草组及模型组大鼠血清INS水平及肝组织胰岛素酶活性与正常组大鼠差异无显著意义 (P >0 .0 5 ) ,6,9wk虫草组及模型组大鼠血清INS水平显著高于正常组 (P 3 ) 3 ,6,9wk虫草组大鼠血清INS水平及肝组织胰岛素酶活性与对应模型组差异无显著意义(P >0 .0 5 )。结论 :虫草菌丝可减轻CCl4对肝细胞的损伤 ,并可抑制肝纤维化 ;造模 6wk后实验性肝硬化大鼠肝组织胰岛素酶活性开始降低。

关键词：肝硬化胰岛素溶酶大鼠虫草菌丝

免疫球蛋白对缺血缺氧性脑损伤新生大鼠的保护作用及其机制研究

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中国妇幼保健 2013年第29期28卷 4862-4864页

作者：黄秀兰唐兰芬乔智慧广东医学院附属医院儿科广东湛江524001

目的:研究免疫球蛋白对新生大鼠缺血缺氧性脑损伤(HIBD)时炎症因子抵抗素、白细胞介素-1β(IL-1β)和NF-κB p65表达的影响。方法:建立HIBD模型;将72只新生7日龄SD仔鼠随机分为3组:假手术组(n=24),HIBD组(n=24,腹腔内注射生理盐水,0.02... 详细信息

目的:研究免疫球蛋白对新生大鼠缺血缺氧性脑损伤(HIBD)时炎症因子抵抗素、白细胞介素-1β(IL-1β)和NF-κB p65表达的影响。方法:建立HIBD模型;将72只新生7日龄SD仔鼠随机分为3组:假手术组(n=24),HIBD组(n=24,腹腔内注射生理盐水,0.02 ml·g-1·次-1,2次/d,共2天),治疗组(n=24,腹腔内注射免疫球蛋白,2.5 mg·g-1·次-1,2次/d,共2天)。每个组按照12 h、24 h、72 h时间点分为3个亚组,每亚组8只;以免疫组化法检测病变侧脑组织中抵抗素、IL-1β和NF-κB p65的水平。结果:抵抗素、IL-1β及NF-κB p65在假手术组均只有少量表达,各时间点之间比较差异无统计学意义(P>0.05);抵抗素、IL-1β及NF-κB p65在HIBD组12 h表达开始增高,24 h达到高峰,随时间进展,其表达量逐渐减少;与假手术组各时间点相比,HIBD组和治疗组抵抗素、IL-1β及NF-κB p65表达均增高,差异有统计学意义(P<0.05);与HIBD组相比,治疗组12 h、24 h、72 h抵抗素、IL-1β及NF-κB p65表达量减少,差异有统计学意义(P<0.05)。结论:NF-κB p65、抵抗素及IL-1β在HIBD大鼠中表达上调,免疫球蛋白能下调NF-κB p65、抵抗素及IL-1β的表达。

关键词：缺血缺氧性脑损伤抵抗素白细胞介素-1β NF-κB p65免疫球蛋白