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甲磺酸氨氯地平与苯磺酸氨氯地平治疗原发性高血压的比较

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中国新药与临床杂志 2003年第2期22卷 71-74页

作者：王启贤杨源杨西云赵玲昆明医学院第一附属医院心血管内科云南昆明650032

目的 :甲磺酸氨氯地平与苯磺酸氨氯地平治疗原发性高血压的疗效比较。方法 :1 2 2例原发性高血压病人 ,68例给予甲磺酸氨氯地平 ,另外 5 4例服用苯磺酸氨氯地平 ,均 5～ 1 0mg,qd× 8wk。治疗前后作血压测定、血生化检验、血常规、尿常... 详细信息

目的 :甲磺酸氨氯地平与苯磺酸氨氯地平治疗原发性高血压的疗效比较。方法 :1 2 2例原发性高血压病人 ,68例给予甲磺酸氨氯地平 ,另外 5 4例服用苯磺酸氨氯地平 ,均 5～ 1 0mg,qd× 8wk。治疗前后作血压测定、血生化检验、血常规、尿常规、心电图。结果 :甲磺酸氨氯地平与苯磺酸氨氯地平总有效率分别为 97%和 96% ,显效率为 82 %和74% ,2组比较差异无显著意义 (P >0 .0 5 ) ;2组不良反应均轻微 ,组间比较无统计学差异。结论 :甲磺酸氨氯地平与苯磺酸氨氯地平一样治疗有效、安全 ,不良反应少 ,而且有良好的耐受性 ,是轻。

关键词：甲磺酸氨氯地平苯磺酸氨氯地平治疗原发性高血压疗效比较

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肾脏病治疗饮食不遵医行为的调查

实用护理杂志 2001年第8期17卷 45-46,55页

作者：徐素梅方进濮玉平南京医科大学附属淮阴市第一医院肾内科江苏淮阴223300

目的了解肾脏病患者治疗饮食不遵医情况。方法采用自编肾脏病患者饮食遵医调查问卷表，对 108例肾脏病患者的饮食不遵医情况进行调查。结果有63例不能按医嘱进食，占调查人数的 58.33%。结论年龄、文化程度、疾病类型、病程长短、... 详细信息

目的了解肾脏病患者治疗饮食不遵医情况。方法采用自编肾脏病患者饮食遵医调查问卷表，对 108例肾脏病患者的饮食不遵医情况进行调查。结果有63例不能按医嘱进食，占调查人数的 58.33%。结论年龄、文化程度、疾病类型、病程长短、家庭经济水平，患者对治疗饮食的了解程度，是影响治疗饮食不遵医行为的主要原因。

关键词：肾脏病不遵医行为调查治疗饮食疗法

COMPARISON OF THE EFFECTIVENESS BETWEEN ANTERIOR CAPSULOTOMY WITH Nd:YAG LASER AND WITH BENT NEEDLE IN PATIENTS WITH CONGENITAL CATARACT

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眼科学报 1991年第3期7卷 125-127,124页

作者： Zhende Lin Shaozhen Li Eye hospital, Zhongshan Ophthalmic Center Sun Yat-sen University of Medical Sciences Guangzhou 510060,China Eye hospital Zhongshan Ophthalmic Center Sun Yat-sen University of Medical Sciences Guangzhou China.

The effectiveness of capsulotomy with Nd:YAG laser and with bent needle were compared in 50 patients(66 eyes) with congenital cataract. There were 24 patients(32 eyes) in the laser group and 26 patients(34 eyes) in the needle group. There were not significant differences in sex, age, pre-operative visual acuity and intraocular pressures, and classification of cataract between the two groups. The results show that patients in the laser group have better post-operative visual acuity. The reason is YAG las...

关键词： YAG COMPARISON OF THE EFFECTIVENESS BETWEEN ANTERIOR CAPSULOTOMY WITH Nd Nd

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吴银根运用膏方治疗支气管扩张经验

上海中医药杂志 2010年第1期44卷 22-24页

作者：方泓唐斌擎上海中医药大学附属龙华医院上海200032

总结吴银根教授运用膏方治疗支气管扩张的经验:以平为期,平衡标本正邪与动静升降;注重辨痰、辨咯血及辨兼病。并举医案3则以说明。

关键词：支气管扩张膏方名医经验吴银根

Expression of the somatostatin receptor family mRNAs inlung cancer

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Nuclear Science and Techniques 2000年第4期11卷 253-256页

作者： WANG Jing, WANG Lian-Gang, WU Sheng-Xi, DENG Jing-Lan ( Xijing hospital, The Fourth Military Medical University, Xi'an 710032 Department of Anatomy, The Fourth Military Medical University, Xi'an 7100032 ) 第四军医大学陕西西安 710032

To investigate the characteristics of expression and distribution of 5 subtypes of somatostatin receptors (SSTR1～5) in lung cancer, in situ hybridization was used to examine the expression patterns of SSTR mRNAs in 21 cases of different pathologic types of lung cancer tissues with [a-35S]dATP labeled oligonucleotides of the 5 SSTR subtypes as probes. Additionally, Leica Q-500 image analysis processing system was employed for the semi-quantitatively analysis of the hybridization signals. Patterns of SSTR1～5 expression in lung cancer tissues were found as follows. SSTR2 was prominent in small cell lung cancer (SCLC), whereas in non-small cell lung cancer (NSCLC) including the adenous cancer (Ad) and the squamous cancer (Sq), the expression of SSTR1 mRNA was stronger than that of the other 4 types. The expression density of SSTR1～5 in the NSCLC was higher than the SCLC (p <0.01). The expression patterns and densities of the SSTR subtypes showed heterogeneity in different pathologic types of lung cancer. The expressions of the SSTR mRNAs in both SCLC and NSCLC indicated the positive prospects for somatostatin analog(SSA)--oriented agents in the treatment of both types of the lung cancer.

关键词： Somatostatin receptor Lung neoplasms In situ hybridization

High frequency of p53 intronic point mutations in laryngeal squamous cell carcinoma

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Progress in Natural Science:Materials International 2004年第7期 36-40页

作者： ZHAO Xu 1*, LI Fucai 1*, SONG Yutong 2, LI Yinghui 1, FU Weineng 1, XU Zhenming 3 and SUN Kailai 1(1. Department of Medical Genetics, China Medical University, Shenyang 110001, China 2. Department of Biochemistry and Molecular Biology, China Medical University, Shenyang 110001, China 3. Department of Otolaryngology, No.463 hospital of Air-Force, Shenyang 110001, China) Department of Medical Genetics China Medical University Shenyang 110001 China Department of Biochemistry and Molecular Biology China Medical University Shenyang 110001 China Department of Otolaryngology No.463 Hospital of Air-Force Shenyang 110001 China

Intronic point mutations are rare and totally unknown for human laryngeal squamous cell carcinoma (LSCC). To explore the relationship of p53 gene intronic mutation to the development of human LSCC, DNA was extracted from both tumor tissues and matched normal tissues of 55 patients with LSCC in northeast of China. Polymerase chain reaction amplification-single strand conformational polymorphism (PCR-SSCP) combined with silver staining and DNA direct sequencing were used to detect mutations in exons 7～8 (p53E7 and p53E8) and introns 7～8 (p53I7 and p53I8) of p53 gene. The p53E7 mutation was detected in 17 out of 55 patients, and the p53I7 mutation in 21 patients. No mutation was found at p53E8 or p53I8 site. The difference between tumor group and paired normal group on the rates of both p53E7 and p53I7 mutations was statistically significant. The rate of p53I7 mutations in tumor tissue was higher than that of normal tissue, and so was that of p53E7. Sequence analysis revealed that most p53I7 mutations were at the nucleotides in the branch point sequence or the polypyrimidine tract in the 3′-splice acceptor site of the intron 7. The high incidence of p53 gene intronic mutation in LSCC indicates that genetic changes within the noncoding region of the p53 gene may serve as an alternative mechanism of activating the pathogenesis of human laryngeal squamous cell carcinoma. Mutations in the noncoding region of this gene should be further studied.

关键词： laryngeal squamous cell carcinoma p53 gene intronic mutation PCR-SSCP.

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口咽恶性肿瘤切除及修复手术的护理配合

护理研究 2008年第2期22卷 150-151页

作者：刘志瑛复旦大学附属眼耳鼻喉科医院

对位于口咽侧壁和口腔后外部的鳞癌,目前多采用放射治疗,但仍然有一部分病例放疗无法完全控制肿瘤而导致复发,对于这些病例手术切除是唯一的补救措施.近年来,随着头颈外科修复技术的发展,使口咽恶性肿瘤的外科治疗取得了较满意的疗效.

关键词：口咽恶性肿瘤护理配合巡回护士电刀手术敷料修复手术

Performance of a Colorectal Cancer Screening Protocol in an Economically and Medically Underserved Population

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Performance of a Colorectal Cancer Screening Protocol in an ...

全国肿瘤流行病学和肿瘤病因学学术会议

作者： Shan-Rong Cai~1,Su-Zhan Zhang~(1$),Hong-Hong Zhu~(2$),Yan-Qin Huang~1, Qi-Rong Li~3,Xin-Yuan Ma~3,Kai-Yan Yao~3,Shu Zheng~(1*) 1.Cancer Institute(Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education,Key Laboratory of Molecular Biology in Medical Science,Zhejiang province,China),2nd affiliated hospital,School of Medicine, Zhejiang University,Hangzhou,Zhejiang,310009,P.R.China 2.Division of Epidemiology,Department of Community Health,Saint Louis University School of Public Health,St.Louis,MO,63104,USA 3.Institute of Oncology Prevention and Treatment,Jiashan,Zhejiang,314100,P.R. China

＜正＞The performance of combining fecal immunochemical tests（FITs） and a high risk factor questionnaire（HRFQ） in colorectal cancer（CRC） screening in economically and medically underserved populations is *** study investigated the performance of a CRC screening protocol of combining FITs and an HRFQ as primary screening methods in a rural Chinese population.A CRC mass screening was conducted using FITs and an HRFQ as the first and colonoscopy as the second phase of screening in Jiashan,*** target population was 31,963 residents in three *** with positive results in the first and second phase screening were followed up by different *** compliance was 84.7%in the first phase and 78.7%for *** Positive Value（PPV） of FITs for CRC,adenoma,advanced,and total neoplasm was higher than that of HRFQ except polyps,*** of the screening protocol of combining FITs and HRFQ for advanced neoplasm was 5.7%,higher than FITs alone.A total of 41.2%adenomas,53.2%polyps,and 29.8%advanced neoplasms were detected by HRFQ but missed by *** had a higher prevalence of advanced neoplasm than *** indicate combining FITs and HRFQ as primary screening methods is an efficient CRC screening strategy in economically and medically underserved populations.

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10kg以下婴幼儿先天性心脏病的外科治疗

上海医学 2005年第1期28卷 55-57页

作者：范太兵李群石磊苏肇伉丁文祥郑州大学第三附属医院小儿先心病诊疗中心 450052 上海第二医科大学附属新华医院

目的探讨婴幼儿先天性心脏病的手术时机、方法及围术期处理对策.方法我院2001年1月～2003年6月连续手术治疗10 kg以下先天性心脏病患婴92例,男56例,女36例,平均月龄为(6.3±2.6)个月(2.5～12.7个月),平均体重为(6.8±1.2)kg(3.5～10.0 k... 详细信息

目的探讨婴幼儿先天性心脏病的手术时机、方法及围术期处理对策.方法我院2001年1月～2003年6月连续手术治疗10 kg以下先天性心脏病患婴92例,男56例,女36例,平均月龄为(6.3±2.6)个月(2.5～12.7个月),平均体重为(6.8±1.2)kg(3.5～10.0 kg).室间隔缺损(VSD)55例(56.5%),法洛四联症8例(8.7%),房间隔缺损7例(7.6%),动脉导管未闭18例(19.6%),主动脉缩窄、单心室、右室双出口和假性动脉瘤各1例(1.1%).结果全组死亡2例,死亡率为2.2%.并发症:呼吸机通气相关性肺炎3例(3.2%),残余VSD 2例(2.2%),暂时性Ⅲ度房室传导阻滞、反应性肺高压危象、术后出现严重低氧血症和假性动脉瘤形成伴乳糜胸各1例(1.1%).结论小儿先天性心脏病在婴幼儿期治疗可以取得满意的疗效.符合婴幼儿生理特点的治疗对策是成功的关键.

关键词：先天性心脏病 10kg以下婴幼儿 VSD 假性动脉瘤并发症外科治疗 Ⅲ度房室传导阻滞呼吸机通气气相