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Organic X-Ray Image Sensors Using a Medium Bandgap Polymer Donor with Low Dark Current

Energy & Environmental Materials 2024年第6期7卷 230-237页

作者： Jong-Woon ha Seung Hun Eom Bo Kyung Cha Seyeong Song Hyeong Ju Eun Jong H.Kim Jong Mok Park BongSoo Kim Byoungwook Park Seo-Jin Ko Sung Cheol Yoon Changjin Lee In Hwan Jung Do-Hoon Hwang Department of Chemistry Chemistry Institute for Functional MaterialsPusan National UniversityBusan 46241Korea Division of Advanced Energy Materials Research Center Korea Research Institute of Chemical Technology(KRICT)Daejeon 34114Korea Electro-Medical Device Research Center Korea Electrotechnology Research Institute(KERI)Ansan 15588Korea Graduate School of Carbon Neutrality School of Energy and Chemical EngineeringUlsan National Institute of Science and Technology(UNIST)Ulsan 44919Korea Department of Molecular Science and Technology Ajou UniversitySuwon 16449Korea Research Center for Advanced Specialty Chemicals Korea Research Institute of Chemical TechnologyUlsan 44412Korea Department of Chemistry Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Korea Department of Organic and Nano Engineering Human-Tech Convergence ProgramHanyang University222 Wangsimni-roSeongdong-guSeoul 04763Korea

The development of portable X-ray detectors is necessary for diagnosing fractures in unconscious patients in emergency ***,this is quite challenging because of the heavy weight of the scintillator and silicon *** weight and thickness of X-ray detectors can be reduced by replacing the silicon layer with an organic *** study presents a novel bithienopyrroledione-based polymer donor that exhibits excellent photodetection properties even in a thick photoactive layer(~700 nm),owing to the symmetric backbone and highly soluble molecular structure of *** ability of bithienopyrroledione-based polymer donor to strongly suppress the dark current density(Jd~10−10 A cm^(−2))at a negative bias(−2.0 V)while maintaining high responsivity(R=0.29 A W−1)even at a thickness of 700 nm results in a maximum shot-noise-limited specific detectivity of D_(sh)^(*)=2.18×10^(13)Jones in the organic *** organic photodetectors are developed by slot-die coating for use in X-ray detectors,which exhibit D_(sh)^(*)=2.73×10^(12)Jones with clear rising(0.26 s)and falling(0.29 s)response times upon X-ray *** reliability is also proven by linear response of the X-ray detector,and the X-ray detection limit is 3 mA.

关键词： low dark current low detection limit organic photodetector printable X-ray

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新兴和发展中经济体的资本管制与美国货币政策的传导

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新金融 2024年第4期 21-28,36页

作者： Jongrim ha haiqin Liu John Rogers 李丽丽(译) 周正铭(译) 世界银行复旦大学不详

与发达经济体相比,新兴市场和发展中经济体(EMDEs)的资产收益波动性要大得多。学术界对此现象的研究结果是“各国无法从全球金融周期中脱钩”。文章利用1995—2019年间78个国家的结构向量自回归模型,以及文献中识别美国货币政策冲击的... 详细信息

与发达经济体相比,新兴市场和发展中经济体(EMDEs)的资产收益波动性要大得多。学术界对此现象的研究结果是“各国无法从全球金融周期中脱钩”。文章利用1995—2019年间78个国家的结构向量自回归模型,以及文献中识别美国货币政策冲击的不同方法,检验了资本账户开放程度较低的国家对美国货币政策冲击的系统性反应小于资本管制宽松的国家这一命题。文章还考虑了汇率制度和外汇干预等其他制度特征在解释各国对冲击的反应差异方面的作用。实证结果表明:较严格的资本管制会使利率和汇率对美国货币政策冲击的反应较小,该结果在新兴市场经济国家中更为显著;只有微弱的证据表明汇率的灵活程度会影响美国对外国利率和汇率的溢出效应。本刊编译此篇世界银行的研究报告,以飨读者。

关键词：资本管制溢出效应资本流动管理全球金融周期美联储

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强噪环境下分频段数字音频信号精细化采集研究

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现代电子技术 2024年第11期47卷 64-68页

作者：哈筝山西大学音乐学院山西太原030006

在强噪环境下,为了获取高质量、低失真度的数字音频信号,提出一种强噪环境下分频段数字音频信号精细化采集方法。通过麦克风设备获取音频信号,利用LM4550芯片对其作采样、编码等处理后生成数字音频信号,基于AC-97单元接收数字音频信号,... 详细信息

在强噪环境下,为了获取高质量、低失真度的数字音频信号,提出一种强噪环境下分频段数字音频信号精细化采集方法。通过麦克风设备获取音频信号,利用LM4550芯片对其作采样、编码等处理后生成数字音频信号,基于AC-97单元接收数字音频信号,利用频段分割器对其作频带分解,获得互不重叠子频段数字音频信号。采用多窗谱谱减法对其去噪,利用数据通信接口将其传输给LM4550芯片,在完成模拟信号转换后,通过耳机输出,实现数字音频信号精细化采集。实验结果表明,该方法处理后的各子频段数字音频信号有用信息得以完整保留,并提高了信号波形的规整度和规律性,强噪声环境下数字音频信号的PESQ指标达到4.08以上,最大失真度为3.74%。

关键词：强噪环境分频段数字音频信号 FPGA 频段分割器多窗谱谱减法通信接口模拟信号

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Neuralgic amyotrophy with hourglass-like constrictions:A case report

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World Journal of Clinical Cases 2024年第34期12卷 6728-6735页

作者： Mi-Hyeon Bang ha-Lim Song Seok hahn Wanil Kim Hwan-Kwon Do Department of Physical Medicine and Rehabilitation Haeundae Paik HospitalInje University College of MedicineBusan 48108South Korea Department of Radiology Haeundae Paik HospitalInje University College of MedicineBusan 48108South Korea Division of Biochemistry Department of Convergence Medical ScienceInstitute of Medical ScienceGyeongsang National University College of MedicineJinju 52727South Korea Department of Physical Medicine and Rehabilitation Dongnam Institute of Radiological and Medical SciencesBusan 46033South Korea

BACKGROUND Neuralgic amyotrophy(NA)is a rare disease with sudden upper limb pain followed by affected muscle *** most commonly affected area in NA is the upper part of the brachial plexus,and the paraspinal muscles are rarely affected(1.5%),making these cases difficult to distinguish from cervical *** SUMMARY A 76-year-old male presented to the emergency department with left hip pain *** undergoing left femoral neck fracture surgery,he experienced sudden left shoulder pain for 10 days with subsequent left arm *** spine computed tomography revealed mild right asymmetric intervertebral disc bulging with a decreased C5-6disc *** weeks later,an electrodiagnostic study confirmed brachial plexopathy findings involving the cervical *** resonance neurography was performed for a differential *** enhancement was identified at the upper trunk of the brachial plexus,including the C5 nerve root.A suprascapular nerve hourglass-like focal constriction(HLFC)was also identified,confirming *** being diagnosed with NA,the patient received 15 mg prednisolone,twice daily,for 3 *** therapy was initiated,including left arm strengthening exercises and electrical stimulation *** shoulder muscle strength significantly improved one CONCLUSION NA's unique features like HLFC and paraspinal involvement are crucial for accurate diagnosis,avoiding confusion with cervical radiculopathy.

关键词： Neuralgic amyotrophy Cervical radiculopathy Hourglass-like focal constriction Paraspinal muscle Magnetic resonance neurography Case report

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Generation of double knockout cattle via CRISPR-Cas9 ribonucleoprotein(RNP)electroporation

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Journal of Animal Science and Biotechnology 2024年第1期15卷 456-462页

作者： Gyeong-Min Gim Kyeong-Hyeon Eom Dong-Hyeok Kwon Dae-Jin Jung Dae-Hyun Kim Jun-Koo Yi Jae-Jung ha Ji-Hyun Lee Seong-Beom Lee Woo-Jae Son Soo-Young Yum Won-Wu Lee Goo Jang Laboratory of Theriogenology and Biotechnology Department of Veterinary Clinical ScienceCollege of Veterinary Medicine and the Research Institute of Veterinary ScienceSeoul National UniversitySeoulRepublic of Korea LARTBio Co. Ltd.SeoulRepublic of Korea Gyeongsangbukdo Livestock Research Institute YeongjuRepublic of Korea Comparative Medicine Disease Research Center Seoul National UniversitySeoulRepublic of Korea

Background Genome editing has been considered as powerful tool in agricultural ***,genome editing progress in cattle has not been fast as in other mammal species,for some disadvantages including long gestational periods,single pregnancy,and high raising ***,technically demanding methods such as microinjection and somatic cell nuclear transfer(SCNT)are needed for gene editing in *** this point of view,electroporation in embryos has been risen as an *** First,editing efficiency of our electroporation methods were tested for *** of mutation on embryo was confirmed by T7E1 *** first combination,mutation rates for MSTN and PRNP were 57.6%±13.7%and 54.6%±13.5%,*** case of MSTN/BLG,mutation rates were 83.9%±23.6%for MSTN,84.5%±18.0%for ***,the double-KO embryos were transferred to surrogates and mutation rate was identified in resultant calves by targeted deep *** recipients were transferred for MSTN/PRNP,4 calves were delivered,and one calf underwent an induction for double *** surrogates were given double-KO embryos for MSTN/BLG,and four of the six calves that were born had mutations in both *** These data demonstrated that production of genome edited cattle via electroporation of RNP could be effectively ***,MSTN and PRNP from beef cattle and MSTN and BLG from dairy cattle have been born and they will be valuable resources for future precision breeding.

关键词： Beta-lactoglobulin Cattle CRISPR-Cas9 Electroporation Knockout MSTN PRNP

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Comparison of Treatment Efficacy of Different Number of Botulinum Toxin Type A Injection Sites for Crow’s Feet Lines: A Single-Center Retrospective Clinical Study in Vietnam

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International Journal of Dermatology and Venereology 2024年第3期7卷 131-136页

作者： Minh Nguyen Quang Mai Le Thi Hieu Duong Phuc ha Vu Thai Doanh Le Huu Department of Stem Cell Research and Application National Hospital of Dermatology and VenereologyHanoi 100000Vietnam Department of Healthcare Activity Direction National Hospital of Dermatology and VenereologyHanoi 100000Vietnam Department of Dermatology Hanoi Medical UniversityHanoi 100000Vietnam

Objective:Botulinum toxin type A is frequently used to treat crow’s feet ***,the optimal dose and injection sites are still *** objective of this study was to compare the efficacy of different botulinum toxin type A injection patterns for the treatment of crow’s ***:This single-center,retrospective,clinical study was conducted at the National Hospital of Dermatology and Venereology from July 2020 to December *** on 60 patients with crow’s feet were collected and divided into 2 groups(3-or 4-point intramuscular injection)according to the intramuscular injection technique the patients *** treatment efficacy was assessed based on the changes in the Crow’s Feet Grading Scale score at 1,4,and 16 weeks after *** measures analysis of variance was used for the assessment of changes in scores over time between the two ***:After treatment,the average Crow’s Feet Grading Scale score was significantly decreased compared with the pretreatment score at all timepoints(1,4,and 16 weeks)in both states(dynamic:For 3-point intramuscular injection technique,1 week:1.90±0.71 vs.2.97±0.56;4 weeks:1.87±0.68 vs.2.97±0.56;16 weeks:2.60±0.67 vs.2.97±*** 4-point intramuscular injection technique,1 week:1.73±0.83 vs.3.03±0.49;4 weeks:1.73±0.74 vs.3.03±0.49;16 weeks:2.57±0.68 vs.3.03±0.49,all Phan in the 3-point injection group(P=0.028).The adverse events were post-injection bruising in 3 patients and a feeling of eyelid tightness in 3 ***:Botulinum toxin type A injecti

关键词： botulinum toxin type A crow’s feet lines injection site dose

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An oxygenating colloidal bioink for the engineering of biomimetic tissue constructs

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Bio-Design and Manufacturing 2024年第3期7卷 240-261页

作者： Seol-ha Jeong Jarno Hiemstra Patrick V.Blokzijl Rebeca Damian-Ferrara Danilo Martins dos Santos Jéssica H.L.da Fonseca Min-Ho Kang Jihyun Kim Dilara Yilmaz-Aykut Mei L.L.Cham-Pérez Jeroen Leijten Su Ryon Shin Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02139USA Leijten Lab Department of Developmental BioEngineeringFaculty of Science and TechnologyTechnical Medical CentreUniversity of TwenteDrienerlolaan 57522 NB EnschedeThe Netherlands Nanotechnology National Laboratory for Agriculture(LNNA) Embrapa InstrumentaçãoSao CarlosSao Paulo 13560-970Brazil Department of Biomedical-Chemical Engineering The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea Department of Biotechnology The Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do 14662Republic of Korea

Ensuring a sufficient oxygen supply is pivotal for the success of bioprinting applications since it fosters tissue integration and natural *** in oxygen concentration among diverse tissues necessitates the precise recreation of tissue-specific oxygen levels in imprinted constructs to support the survival of targeted *** oxygen-releasing biomaterials,such as oxygen-generating microparticles(OMPs),have shown promise for enhancing the oxygen supply of microenvironments in injured tissues,whether this approach is scalable for large tissues and whether tissue-specific bioinks with varying OMP concentrations remain printable remain *** study addresses this critical gap by introducing an innovative class of engineered oxygenated bioinks that combine colloidal-based microgels with *** report that incorporating nanosized calcium peroxide(nCaO_(2))and manganese oxide nanosheets(nMnO_(2))into hydrophobic polymeric microparticles enables precise modulation of oxygen release while controlling hydrogen peroxide ***,the fabrication of oxygenating and cytocompatible colloidal gels is achieved using an aqueous two-phase *** study thoroughly evaluates the fundamental characteristics of the resulting bioink,including its rheological behaviors,printability,shape fidelity,mechanical properties,and oxygen release ***,this study demonstrates the macroscopic scalability and cytocompatibility of printed constructs produced via cell-laden oxygenating colloidal *** showcasing the effectiveness of extrusion-based bioprinting,this study underscores how it can be used to fabricate biomimetic tissues,indicating its potential for new *** findings presented here advance the bioprinting field by achieving scalability with both high cell viability and the possibility of mimicking specifically oxygenated *** work thereby offers a promising avenue for the development of functional tissues with e

关键词： 3D bioprinting Bioink Colloidal gels Extrusion printing Oxygen-generating microparticle

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Endobronchial metastasis secondary to renal clear cell carcinoma:A case report

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World Journal of Clinical Cases 2024年第23期12卷 5416-5421页

作者： Tian-hao Xie Yan Fu Si-Ning ha Qing-Xu Meng Qian Sun Pan Wang Department of General Surgery The Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina Department of Ophthalmology Baoding First Central HospitalBaoding 071000Hebei ProvinceChina Department of Pathology The Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina

BACKGROUND Endobronchial metastases(EBMs)are tumours that metastasise from a malignant tumour outside the lungs to the central and subsegmental bronchi,and are visible under a *** EBMs are formed by direct invasion or metastasis of intrathoracic malignant tumours,such as lung cancer,oesophageal cancer or mediastinum *** cell carcinoma(RCC),accounting for 2%to 3%of all tumours,is a common malignant tumour of the urinary *** clear cell carcinoma(RCCC)constitutes the predominant pathological subtype of RCC,comprising approximately 70%to 80%of all RCC *** can spread and metastasise through arterial,venous and lymphatic circulation to almost all organs of the ***,lung,bone,liver,brain and local recurrence are the most common metastatic neoplasms of ***,EBM from RCCC has a low complication rate and is often misdiagnosed as primary lung *** SUMMARY A 71-year-old male patient who had undergone radical left nephrectomy 7 years prior due to RCCC was referred to our hospital due to a 1-mo history of productive *** results of an enhanced chest CT scan indicated the presence of a soft tissue nodule in the upper lobe of the left lung,and flexible bronchoscopy revealed a hypervascular lesion in the bronchus of the left lung's superior ***,the patient underwent thoracoscopic left superior lobe wedge resection,and pathology confirmed EBM from the *** EBM from RCCC has a low incidence and no characteristic clinical manifestations in the early *** a bronchial tumour is found in a patient with RCCC,the possibility of bronchial metastatic cancer should be considered.

关键词： Endobronchial metastases Clear renal cell carcinoma Renal cell carcinoma diagnosis Treatment Case report

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Predicting 3D Radiotherapy Dose-Volume Based on Deep Learning

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Intelligent Automation & Soft Computing 2024年第2期39卷 319-335页

作者： Do Nang Toan Lam Thanh Hien ha Manh Toan Nguyen Trong Vinh Pham Trung Hieu Institute of Information Technology Vietnam Academy of Science and TechnologyHanoi10072Vietnam Faculty of Information Technology Lac Hong UniversityBien HoaDong Nai76120Vietnam

Cancer is one of the most dangerous diseaseswith *** of the principal treatments is radiotherapy by using radiation beams to destroy cancer cells and this workflow requires a lot of experience and skill from doctors and *** our study,we focused on the 3D dose prediction problem in radiotherapy by applying the deeplearning approach to computed tomography(CT)images of cancer *** image data has more complex characteristics than normal image data,and this research aims to explore the effectiveness of data preprocessing and augmentation in the context of the 3D dose prediction *** proposed four strategies to clarify our hypothesis in different aspects of applying data preprocessing and *** strategies,we trained our custom convolutional neural network model which has a structure inspired by the U-net,and residual blocks were also applied to the *** output of the network is added with a rectified linear unit(Re-Lu)function for each pixel to ensure there are no negative values,which are absurd with radiation *** experiments were conducted on the dataset of the Open Knowledge-Based Planning Challenge which was collected from head and neck cancer patients treatedwith radiation *** results of four strategies showthat our hypothesis is rational by evaluating metrics in terms of the Dose-score and the Dose-volume histogram score(DVH-score).In the best training cases,the Dose-score is 3.08 and the DVH-score is *** addition,we also conducted a comparison with the results of another study in the same context of using the loss function.

关键词： CT image 3D dose prediction data preprocessing augmentation

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Tuberculosis Diagnosis and Visualization with a Large Vietnamese X-Ray Image Dataset

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Intelligent Automation & Soft Computing 2024年第2期39卷 281-299页

作者： Nguyen Trong Vinh Lam Thanh Hien ha Manh Toan Ngo Duc Vinh Do Nang Toan Faculty of Information Technology Lac Hong UniversityBien HoaDong Nai76120Vietnam Institute of Information Technology Vietnam Academy of Science and TechnologyHanoi10072Vietnam Faculty of Information Technology Hanoi University of IndustryHanoi11915Vietnam

Tuberculosis is a dangerous disease to human life,and we need a lot of attempts to stop and reverse ***,in theCOVID-19 pandemic,access to medical services for tuberculosis has become very *** late detection of tuberculosis could lead to danger to patient health,even *** one of the countries heavily affected by the COVID-19 pandemic,andmany residential areas as well as hospitals have to be isolated for a long *** demands a fast and effective tuberculosis diagnosis solution to deal with the difficulty of accessingmedical services,such as an automatic tuberculosis diagnosis *** our study,aiming to build that system,we were interested in the tuberculosis diagnosis problem from the chest X-ray images of Vietnamese *** chest X-ray image is an important data type to diagnose tuberculosis,and it has also received a lot of attention from deep learning *** paper proposed a novel method for tuberculosis diagnosis and visualization using the deeplearning approach with a large Vietnamese X-ray image *** detail,we designed our custom convolutional neural network for the X-ray image classification task and then analyzed the predicted result to provide visualization as a *** prove the performance of our network model,we conducted several experiments to compare it to another study and also to evaluate it with the dataset of this *** support the implementation,we built a specific annotation system for tuberculosis under the requirements of radiologists in the Vietnam National Lung Hospital.A large experiment dataset was also from this hospital,and most of this data was for training the convolutional neural network *** experiment results were evaluated regarding sensitivity,specificity,and *** achieved high scores with a training accuracy score of 0.99,and the testing specificity and sensitivity scores were over *** on the X-ray image classification result,we visualize pr

关键词： Tuberculosis classification Vietnamese chest X-ray deep learning

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