检索结果-南通市图书馆

Management of Helicobacter pylori infection in Latin America: A Delphi technique-based consensus

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第31期20卷 10969-10983页

作者： Antonio Rollan Juan Pablo Arab M Constanza Camargo Roberto Candia Paul harris Catterina Ferreccio Charles S Rabkin Juan Cristóbal Gana Pablo Cortés Rolando Herrero Luisa Durán Apolinaria García Claudio Toledo Alberto Espino nicole Lustig Alberto Sarfatis Catalina Figueroa Javier Torres Arnoldo Riquelme Clínica Alemana de Santiago Facultad de Medicina Clínica Alemana Universidad del Desarrollo Departamento de Gastroenterología Facultad de Medicina Pontificia Universidad Católica de Chile Division of Cancer Epidemiology and Genetics National Cancer InstituteRockville MD 20852 United States Programa de Salud Basada en Evidencia Pontificia Universidad Católica de Chile Departamento de Gastroenterología y nutrición Pediátrica Facultad de Medicina Pontificia Universidad Católica de Chile Departamento de Salud Pública Facultad de Medicina Pontificia Universidad Católica de Chile International Agency for Research on Cancer World Health Organization Departamento de Microbiología Facultad de Ciencias Biológicas Universidad de Concepción Unidad de Gastroenterología Hospital de Valdivia. Facultad de Medicina Universidad de Austral de Chile Unidad de Investigación en Enfermedades Infecciosas Instituto Mexicano del Seguro Social

AIM: To optimize diagnosis and treatment guidelines for this geographic region, a panel of gastroenterologists, epidemiologists, and basic scientists carried out a structured evaluation of available ***: Relevant questions were distributed among the experts, who generated draft statements for consideration by the entire panel. A modified three-round Delphi technique method was used to reach consensus. Critical input was also obtained from representatives of the concerned medical community. The quality of the evidence and level of recommendation supporting each statement was graded according to United States Preventive Services Task Force ***: A group of ten experts was established. The survey included 15 open-ended questions that were distributed among the experts, who assessed the articles associated with each question. The levels of agreement achieved by the panel were 50% in the first round, 73.3% in the second round and 100% in the third round. Main consensus recommendations included:(1) when available, urea breath and stool antigen test(HpSA) should be used for non-invasive diagnosis;(2) detect and eradicate Helicobacter pylori(H. pylori) in all gastroscopy patients to decrease risk of peptic ulcer disease, prevent o retard progression in patients with preneoplastic lesions, and to prevent recurrence in patients treated for gastric cancer;(3) further investigate implementation issues and health outcomes of H. pylorieradication for primary prevention of gastric cancer in high-risk populations;(4) prescribe standard 14-d triple therapy or sequential therapy for first-line treatment;(5) routinely assess eradication success post-treatment in clinical settings; and(6) select second- and third-line therapies according to antibiotic susceptibility ***: These achievable steps toward better region-specific management can be expected to improve clinical health outcomes.

关键词： Helicobacter pylori Consensus development conferen

世界卫生组织(WHO)造血与淋巴组织肿瘤分类方案:临床顾问委员会会议报告

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

白血病．淋巴瘤 2001年第3期10卷 171-181页

作者： n L harris E S Jaffe J Diebold G Flandrin H K Muller-Hermelink J Vardiman T A Lister C D Bloomfield 张凤奎郝玉书世界卫生组织中国医学科学院中国协和医科大学血液病医院

引言 :从 1995年开始 ,欧洲病理学工作者协会和血液病理学会一直致力于制定一个新的世界卫生组织 (WHO)血液恶性肿瘤分类方案 ,该分类方案包括淋巴系肿瘤、髓系肿瘤、组织细胞肿瘤和肥大细胞肿瘤。　　材料与方法 :此项 WHO计划共组成... 详细信息

引言 :从 1995年开始 ,欧洲病理学工作者协会和血液病理学会一直致力于制定一个新的世界卫生组织 (WHO)血液恶性肿瘤分类方案 ,该分类方案包括淋巴系肿瘤、髓系肿瘤、组织细胞肿瘤和肥大细胞肿瘤。　　材料与方法 :此项 WHO计划共组成十个病理学工作者委员会 ,负责确定病种和作出定义。另外还成立一个由国际血液学家和肿瘤学家组成的临床顾问委员会 (CAC)以保证该分类的临床实用性。 1997年 11月召开会议讨论了与该分类有关的临床问题。　　结果 :WHO采纳了 1994年国际淋巴瘤研究组 (IL SG)报告的修订欧美淋巴系肿瘤分类 (REAL)方案作为淋巴系肿瘤的分类方案。该方案的分类方法遵循以下原则 :分类应是联合应用形态学、免疫表型、遗传特征及临床特征能够清楚界定的“真实存在”(“real”)病种的名录 ,上述各项特征的相对重要性因病种不同而异 ,不存在任何“金标准”。 WHO将 REAL分类原则延用于髓系肿瘤和组织细胞肿瘤 ,髓系肿瘤的分类包括联合应用细胞形态学和细胞遗传学异常能够界定的各个病种。围绕一系列临床问题召集的这次 CAC会议 ,就提交的大多数问题达成共识 ,这些问题及共识将详述于下。对于另外一些问题 ,CAC认为淋巴系肿瘤临床分组既无必要也不必需 ,患者的治疗取决于淋巴瘤的具体类型 ,如有?

关键词：淋巴瘤白血病髓系肥大细胞组织细胞分类

温度测量结果表明日本东北地区近海断层存在低速同震摩擦

在线全文

学校读者我要写书评

暂无评论

国际地震动态 2015年第8期36卷 3-8页

作者： P M Fulton E E Brodsky Y Kano J Mori F Chester T Ishikawa R n harris W Lin n Eguchi S Toczko 343T和KR13-08勘查队科技人员王林 Department of Earth and Planetary Sciences University of California Disaster Prevention Research Institute Kyoto University Center for Tectonophysics Department of Geology and GeophysicsTexas A&M University Kochi Institute for Core Sample Research Japan Agency for Marine-Earth Science and Technology Oregon State University Center for Deep Earth Exploration Japan Agency for Marine-Earth Science and Technology 福建省地震局

断层在滑动时的摩擦阻力控制了地震动力学。地震期间摩擦过程释放热量。因此,地震后的断层温度反映了摩擦程度。日本海沟快速钻井项目(Japan Trench Fast Drilling Project,JFAST)(综合海洋钻探计划((Integrated Ocean Drilling Program... 详细信息

断层在滑动时的摩擦阻力控制了地震动力学。地震期间摩擦过程释放热量。因此,地震后的断层温度反映了摩擦程度。日本海沟快速钻井项目(Japan Trench Fast Drilling Project,JFAST)(综合海洋钻探计划((Integrated Ocean Drilling Program,IODP)343和343T勘探)在2011年3月日本东北地区近海MW9.0地震16个月后,在海沟附近的断层带上钻孔安装了钻孔温度观测仪,该断层带在地震中滑动了约50m。运行9个月后,回收了全部的传感器组。结果发现板块边界断层的异常温度为0.31℃,相当于地震时每平方米释放了27 MJ热量。该研究结果的表面摩擦系数0.08明显小于大多数岩石的静态值。

关键词：温度测量摩擦过程日本海沟东北地区断层带近海 Program 低速

Plasma Fatty Acid Composition in Men over 50 in the USA and Japan

在线全文

学校读者我要写书评

暂无评论

Food and nutrition Sciences 2018年第6期9卷 703-710页

作者： A. Takada F. Shimizu Y. Ishii M. Ogawa T. Takao S. Koba M. R. Carnethon W. S. harris International Projects on Food and Health (nPO) Tokyo Japan Faculty of Human Life and Environmental Sciences Showa Women’s University Tokyo Japan Division of Cardiology Department of Medicine Showa University School of Medicine Tokyo Japan Department of Preventive Medicine Feinberg School of Medicine of Northwestern University Chicago Illinois Department of Medicine University of South Dakota School of Medicine and Omegaquant LLC Sioux Falls USA

Background: Coronary heart disease (CHD) rates differ markedly between the US and Japan. Fatty acid profiles have been linked to risk for CHD. Few studies have compared the plasma fatty acid composition, including trans fatty acids, in Japanese and US subjects. Methods: Fasting blood samples were taken from healthy older (>age 50) American (n = 76) and Japanese (n = 44) men, and plasma levels of 23 fatty acids were analyzed by gas chromatography and expressed as a percent of total fatty acids. Results: As expected, plasma levels of long-chain ω3 fatty acids (docosahexaenoic and eicosapentaenoic acids, DHA and EPA) were higher in Japanese men and ω6 fatty acids (e.g., arachidonic acid, AA) were lower compared with American men. Plasma levels of the major industrially-produced trans fatty acids (IP-TFAs;elaidic and linoelaidic acids) were far higher in American men, and levels of the potentially cardioprotective, primarily ruminant-derived trans fatty acid palmitoelaidic acid (POA) were higher in Japanese. Plasma levels of saturated or monounsaturated fatty acids were also higher in the American men. Conclusion: There are multiple differences in plasma fatty acid profiles between American and Japanese older men. The higher levels of DHA and EPA, along with the lower levels of the IP-TFAs, are consistent with the markedly lower risk for coronary heart disease in Japan vs. the US.

关键词： Plasma Fatty Acid Composition

双源CT成像用于经导管主动脉瓣置换术前计划:诊断阻塞性冠状动脉疾病的准确性

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2015年第3期 277-278页

作者： B.S.harris C.n.De Cecco U.J.Schoepf D.H.Steinberg R.R.Bayer A.W.Krazinski 楼清清 Heart and Vascular Center Medical University of South CarolinaAshley River TowerMSC 226 25 Courtenay Dr Charleston SC 29425

目的评估用于经导管主动脉瓣置换(TAVR)术前计划的CT检查对诊断阻塞性冠状动脉疾病(CAD)的准确性。材料与方法经机构伦理委员会批准,免签知情同意书,

关键词：阻塞性冠状动脉疾病双源 CT

高危肥厚型心肌病患者中埋藏式除颤器放电的决定因素

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（心脏病学分册） 2007年第12期3卷 43-44页

作者： Woo A. Monakier D. harris L. 徐永城 Division of Cardiology Toronto General Hospital 4N- 506 200 Elizabeth Street Toronto Ont. M5G 2C4 Canada.Dr

目的:确定肥厚型心肌病(HCM)患者中埋藏式心脏复律除颤器(ICD)适当与不适当放电的决定因素。设计:回顾性队列研究。地点:一所教学医院的ICD门诊。患者:61例出于心脏性猝死(SCD)一级或二级预防目的而植入ICD的HCM患者。观察指标:①适当... 详细信息

目的:确定肥厚型心肌病(HCM)患者中埋藏式心脏复律除颤器(ICD)适当与不适当放电的决定因素。设计:回顾性队列研究。地点:一所教学医院的ICD门诊。患者:61例出于心脏性猝死(SCD)一级或二级预防目的而植入ICD的HCM患者。观察指标:①适当和不适当ICD放电的分析;②ICD放电的预测因素。结果:ICD植入时的年龄(x±s)为46±18岁(极差10～79)。

关键词：肥厚型心肌病 ICD 预测因素患者决定因素

Correlation of n-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第20期13卷 2803-2810页

作者： Minori Koshiji Kensuke Kumamoto Keiichirou Morimura Yasufumi Utsumi Michiko Aizawa Masami Hoshino Shinji Ohki Seiichi Takenoshita Max Costa Thérèse Commes David Piquemal Curtis C harris Kam-Meng Tchou-Wong Department of Environmental Medicine New York University School of Medicine 57 Old Forge Road Tuxedo NY 10987 United States Shinji Ohki Seiichi Takenoshita Second Department of Surgery Fukushima Medical University 1 Hikarigaoka Fukushima 960-1295 Japan Curtis harris National Institutes of Health National Cancer Institute Building 37 Bethesda MD 20892 United States Department of Pathology Osaka City University Osaka Japan Department of Pathology Ohara General Hospital 6-11 Ohmachi Fukushima 960-8611 Japan Department of Surgery Ohara General Hospital 6-11 Ohmachi Fukushima 960-8611 Japan David Piquemal University Montpellier Ⅱ Montpellier France

AIM: To evaluate the role of n-myc downstream-regulated gene 1 (nDRG1) expression in prognosis and survival of colorectal cancer patients with different ethnic backgrounds. METHODS: Because nDRG1 is a downstream target of p53 and hypoxia inducible factor-1α (HIF-1α),we examined nDRG1 expression together with p53 and HIF-1α by immunohistochemistry. A total of 157 colorectal cancer specimens including 80 from Japanese patients and 77 from US patients were examined. The correlation between protein expression with clinicopathological features and survival after surgery was *** colorectal tumor compared with normal epithelium in both Japanese and US patient groups. Expression of nDRG1 protein was significantly correlated with lymphatic invasion,venous invasion,depth of invasion,histopathological type,and Dukes' stage in Japanese colorectal cancer patients. nDRG1 expression was correlated to histopathological type,Dukes' stage and HIF-1α expression in US-Caucasian patients but not in US-African American patients. Interestingly,Kaplan-Meier survival analysis demonstrated that nDRG1 expression correlated significantly with poorer survival in US-African American patients but not in other patient groups. However,in p53-positive US cases,nDRG1 positivity correlated significantly with better survival. In addition,nDRG1 expression also correlated significantly with improved survival in US patients with stages Ⅲ and Ⅳ tumors without chemotherapy. In Japanese patients with stages Ⅱ and Ⅲ tumors,strong nDRG1 staining in p53-positive tumors correlated significantly with improved survival but negatively in patients without chemotherapy. COnCLUSIOn: nDRG1 expression was correlated with various clinicopathological features and clinical outcomes in colorectal cancer depending on the race/ethnicity of the patients. nDRG1 may serve as a biological basis for the disparity of clinical outcomes of colorectal cancer patients with different ethnic backgrounds.

关键词：结肠癌直肠癌基因表达种族临床研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

两万年来的中国多年冻土形成演化

中国科学：地球科学 2019年第8期49卷 1197-1212页

作者：金会军金晓颖何瑞霞罗栋梁常晓丽王绍令 Sergey S MARCHEnKO 杨思忠易朝路李世杰 Stuart A harris 中国科学院寒区旱区环境与工程研究所冻土工程国家重点实验室兰州730000 哈尔滨工业大学土木工程学院哈尔滨150090 中国科学院大学资源与环境学院北京100049 湖南科技大学建筑与城乡规划学院湘潭411201 Permafrost Laboratory Geophysical Institute University of Alaska Fairbanks Fairbanks 99775 USA GFZ German Research Centre for Geosciences Telegrafenberg Potsdam D-14473 Germany 中国科学院青藏高原研究所青藏高原环境变化与地表过程重点实验室北京100010 中国科学院地球化学研究所贵阳550081 Department of Geography University of Calgary Calgary Alberta T2N 1N4 Canada

利用大量的古多年冻土遗迹和古冰缘现象,并佐以古冰川、孢粉及动物化石等资料,重建了20ka以来中国多年冻土演化进程.结果表明,在末次冰期最盛期(LGM,或末次多年冻土最大期LPMax),中国多年冻土面积达到了5.3×10^6~5.4×10^6km^2(现今中... 详细信息

利用大量的古多年冻土遗迹和古冰缘现象,并佐以古冰川、孢粉及动物化石等资料,重建了20ka以来中国多年冻土演化进程.结果表明,在末次冰期最盛期(LGM,或末次多年冻土最大期LPMax),中国多年冻土面积达到了5.3×10^6~5.4×10^6km^2(现今中国多年冻土面积的3倍多),而全新世大暖期(HMP,或末次多年冻土最小期LPMin),中国多年冻土面积曾缩减至0.80×10^6~0.85×10^6km^2(约为现今中国多年冻土面积的50%).按照古冻土遗迹的年代及分布等特征,在确定LGM和HMP两个主要时段的冻土格局基础上,将20ka以来中国多年冻土演化进程划分为7个阶段:晚更新世LGM(20000~10800aBP)多年冻土强烈扩展,达到LPMax;早全新世气候剧变期(10800至8500~7000aBP)多年冻土较稳定但相对缩减阶段;中全新世HMP(8500~7000至4000~3000aBP)多年冻土强烈退化阶段,多年冻土缩减到LPMin;晚全新世新冰期(4000~3000至1000aBP)冻土扩展阶段;晚全新世中世纪暖期(1000~500aBP)多年冻土相对退化阶段;晚全新世小冰期(LIA, 500~100aBP)冻土相对扩展阶段,以及近代升温期(近百年来)多年冻土持续退化阶段.本文重建了各时段内古气候、古地理环境以及多年冻土分布范围和其他特征.

关键词：冻土演化冷生楔形构造末次冰期最盛期(LGM) 全新世大暖期(HMP) 中国