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左室功能不全的患者中微伏T波电交替与死亡或持续性室性心律失常风险的关系

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世界核心医学期刊文摘（心脏病学分册） 2006年第5期2卷 54-54页

作者： Bloomfield d.M Bigger J.T Steinman R.C. 赵君 data Coordinating Center MTWA in CHF Study Columbia University Medical Center 630West 168th Street New York NY 10032 United StatesDr.

OBJECTIVES: this study hypothesized that microvolt T-wave alternans(MTWA) improves selection of patients for implantable cardioverter-defibrillator(ICd) prophylaxis, especially by identifying patients who are not likely to benefit. BACKGROUnd: Many patients with left ventricular dysfunction are now eligible for prophylactic ICds, but most eligible patients do not benefit; MTWA testing has been proposed to improve patient selection. MEthOdS: Our study was conducted at 11 clinical centers in the U.S. Patients were eligible if they had a left ventricular ejection fraction(LVEF) ≤ 0.40 and lacked a history of sustained ventricular arrhythmias; patients were excluded for atrial fibrillation, unstable coronary artery disease, or new York Heart Association functional class IV heart failure. Participants underwent an MTWA test and then were followed for about two years. the primary outcome was all-cause mortality or non-fatal sustained ventricular arrhythmias. RESULTS: Ischemic heart disease was present in 49% , mean LVEF was 0.25, and 66% had an abnormal MTWA test. during 20± 6 months of follow-up, 51 end points(40 deaths and 11 non-fatal sustained ventricular arrhythmias) occurred. Comparing patients with normal and abnormal MTWA tests, the hazard ratio for the primary end point was 6.5 at two years(95% confidence interval 2.4 to 18.1, pnts with normal MTWA tests was 97.5% at two years. the strong association between MTWA and the primary end point was similar in all subgroups tested. COnCLUSIOnS: Among patients with heart disease and LVEF ≤ 0.40, MTWA can identify not only a high-risk group, but also a low-risk group unlikely to benefit from ICd prophylaxis.

关键词：持续性室性心律失常左室功能不全 T波电交替植入埋藏式心脏复律除颤器患者不稳定性冠状动脉疾病风险左室射血分数 nYHA 非致死性

中国男排在第十二届亚洲男排锦标赛上的进攻特点分析

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四川体育科学 2004年第3期23卷 79-80页

作者：董宁许万林西安理工大学体育教学部陕西西安710048

本文通过对中国男排在第12届亚洲男排锦标赛各场比赛进攻效果的分析,总结出其特点即:主攻手与亚洲各队相比能力较强,但发挥不稳定,失误率较高;副攻手扣死率最高,失误率最低,在进攻中主要起牵制作用;主二传二次球的扣死率较高;接应二传... 详细信息

本文通过对中国男排在第12届亚洲男排锦标赛各场比赛进攻效果的分析,总结出其特点即:主攻手与亚洲各队相比能力较强,但发挥不稳定,失误率较高;副攻手扣死率最高,失误率最低,在进攻中主要起牵制作用;主二传二次球的扣死率较高;接应二传在进攻中担任重要角色,占进攻总数的22%,但发挥不稳定。

关键词：中国男子排球队第十二届亚洲男子排球锦标赛进攻特点扣球技术二传训练方法

格林-巴利综合征患者永久性轴突缺失的电生理学特征

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世界核心医学期刊文摘（神经病学分册） 2005年第5期1卷 25-25页

作者： de La Cour C.d. Andersen H. Stlberg E. 李锐 department of neurology Aarhus University Hospital Nφrrebrogade 44 8000 Aarhus C Denmark Dr.

the neurophysiological mechanisms for persisting impairment of motor function after Guillain-Barr syndrome (GBS) were assessed in 37 unselected patients 1- 13 years after diagnosis. For evaluation of reinnervation and axonal loss, macroelectromyography (macro-EMG) including measurement of fiber density (Fd) was performed. data from neuropathy symptom score, neuropathy disability score, nerve conduction studies, and quantitative sensory examination were ranked and s ummed to a neuropathy rank sum score (nRSS). the isokinetic muscle strength at t he ankle was measured. Signs of axonal loss with increase of either macro motor unit potential (macro-MUP) amplitude or Fd occurred in 76% of patients. the macro-MUP amplitude correlated with muscle strength and with nRSS. Patients wi th evidence of residual neuropathy had increased macro-MUP amplitude and Fd as well as decreased muscle strength compared to patients without evidence of res idual neuropathy. We conclude that axonal loss takes place in a substantial numb er of GBS patients and is associated with permanent muscle weakness caused by in sufficient reinnervation. Possible patterns of pathology are discussed in relati on to the macro-EMG findings.

关键词：生理学特征定量感觉检测运动单位电位神经传导肌无力神经支配神经生理机制失能纤维密度

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一种镍镉电池自动充电电路的设计及功能研究

舰船防化 2010年第2期 17-19页

作者：王斌严奉轩陆平李芳凌大鹏中国人民解放军海军司令部军训部中国船舶重工集团公司第七一八研究所

介绍一种新型镍镉电池充电电路,利用集成运放和稳压器组成跟踪式电压比较器,通过监测电池电压实现充电和过充保护功能。经实际验证,该电路能实现自动充电和保护功能。电路使用的都是电子市场上常见的元器件,成本低廉,加之设计简洁,因此... 详细信息

介绍一种新型镍镉电池充电电路,利用集成运放和稳压器组成跟踪式电压比较器,通过监测电池电压实现充电和过充保护功能。经实际验证,该电路能实现自动充电和保护功能。电路使用的都是电子市场上常见的元器件,成本低廉,加之设计简洁,因此有一定的市场潜力。

关键词：镍镉电池充电电路 EdA设计

对因胎儿畸形需终止中期妊娠者行扩张吸取或引产后所致围生期悲伤的比较

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世界核心医学期刊文摘（妇产科学分册） 2005年第10期1卷 9-9页

作者： Burgoine G.A Van Kirk S.d Romm J 张丽娟 Women's Healthcare Associates LLC 19250 SW 65th Ave Tualatin OR 97062 United States.Dr

Objective: this study was undertaken to compare grief resolution after dilation and evacuation (d& E) or induction of labor (IOL) for second- trimester pregnancy termination. Study design: A prospective cohort of 49 women choosing second trimester abortion caused by fetal anomalies by either medical IOL or d& E. depression was evaluated by using the Edinburgh Postnatal depression Scale and bereavement was assessed by using the Perinatal Grief Scale with follow- up to 12 months after pregnancy termination. data were analyzed with χ 2 tests, Mann- Whitney U tests, and independent and paired sample t tests. Results: there was no significant difference in depression incidence on enrollment (61.9% d& E, 53.8% IOL, P = .579), at 4 months (23.5% d& E, 14.3% IOL, P = .252) or 12 months (27.3% d& E, 20.0% IOL, P = .696) or on the PGS at 4 months (74.1 vs 90.2, P = .351) or 12 months (73.3 vs 86.4, P = .658). Conclusion: there is no significant difference in grief resolution among women who terminate a desired pregnancy by either medical or surgical abortion.

关键词：胎儿畸形围生期产后抑郁量表妊娠终止手术流产抑郁状况前瞻性队列研究无显著性差异抑郁发生率配对样本

丘脑静息态功能网络:轻度颅脑外伤者出现异常

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国际医学放射学杂志 2011年第6期 583-583页

作者： d.K.Sodickson L.Miles J.Reaume 孙美丽 Center for Biomedical Imaging Department of RadiologyNew York University School of Medicine660 First Ave4th FloorNew YorkNY 10016

目的采用静息态fMRI探索丘脑的神经纤维功能网络,研究轻度颅脑外伤病人丘脑功能网络是否中断。材料与方法本研究获得伦理委员会批准。24例轻度颅脑外伤病人及17名健康对照者均签署知情同意书。24例病人症状轻重不一,平均病程为22d。使... 详细信息

目的采用静息态fMRI探索丘脑的神经纤维功能网络,研究轻度颅脑外伤病人丘脑功能网络是否中断。材料与方法本研究获得伦理委员会批准。24例轻度颅脑外伤病人及17名健康对照者均签署知情同意书。24例病人症状轻重不一,平均病程为22d。使用基于种子点的全脑相关性分

关键词：丘脑病人间脑颅脑外伤静息态功能网络

中枢神经系统兴奋性过高与谷氨酸脱氢酶获得性功能突变

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世界核心医学期刊文摘（儿科学分册） 2005年第8期1卷 27-27页

作者： Raizen d.M. Brooks- Kayal A. Steinkrauss L. A. Kelly 虎小毅 division of Endocrinology Children's Hospital of Philadelphia 8416 Main Building 34th and Civic Center Boulevard Philadelphia PA 19104 United States Dr.

Objective: To describe seizure phenotypes associated with the hyperinsulinism /hyperammonemia syndrome (HI/HA), which is caused by gain of function mutations in the enzyme glutamate dehydrogenase (GdH). Study design: A retrospective revie w of records of 14 patients with HI/HA. Results: nine patients had seizures as t he first symptom of HI/HA, and six had seizures in the absence of hypoglycemia. no electroencephalogram (EEG) background abnormalities were identified. In four patients, EEG recordings during seizures in the setting of normal blood glucose contained generalized epileptiform discharges. EEGs of three of these patients s howed 0.5- to 2- second generalized irregular spike- and- wave discharge at 3 to 6 Hz corresponding to eye blinks, eye rolling, or staring. the EEG of the f ourth patient consisted of 20 seconds of generalized regular spike- and- wave discharge at 3 Hz in the clinical context of staring and unresponsiveness. In tw o patients, seizure control worsened with carbamezapine or oxcarbezapine treatme nt. Conclusions: In patients with HI/HA, generalized seizures are common and can occur in the absence of hypoglycemia. the drugs carbamazepine and oxcarbazepine should be used with caution for treatment. Pathogenesis of epilepsy in these pa tients may be related to effects of GdH mutations in the brain, perhaps in combi nation with effects of recurrent hypoglycemia and chronic hyperammonemia.

关键词：中枢神经系统谷氨酸脱氢酶性功能癫痫样放电棘慢综合波癫痫发病机制全身发作眼球转动羟化患者病例

病人预期寿命缩短对CT检查辐射的潜在患癌风险的影响

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国际医学放射学杂志 2011年第6期 591-591页

作者： d.J.Brenner I.Shuryak A.J.Einstein 赵晓娟 Center for Radiological Research College of Physicians and SurgeonsColumbia UniversityMedical Center630 W 168th StVC-11-235New YorkNY10032

目的通过比较评价通常需要接受CT检查的患癌病人、心脏病病人与非患癌病人、非心脏病病人的辐射相关性肺癌的患病风险,量化预期寿命缩短对患癌风险的影响。材料与方法运用临床证实的死亡率表,评估需要经常接受

关键词：预期寿命 CABG 结肠癌期望寿命病人肺癌肺肿瘤 CT

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心脏磁共振成像在肥厚型心肌病诊断中的应用

世界核心医学期刊文摘（心脏病学分册） 2006年第1期2卷 40-41页

作者： Rickers C. Wilke n. M. Jerosch-Herold M. B.J. Maron 刘少伟 dr. Minneapolis Heart Institute Foundation 920 E 28th St. Minneapolis MN 55407 United States

Background-Two-dimensional echocardiography is currently the standard test for the clinical diagnosis of hypertrophic cardiomyopathy(HCM). the present study was undertaken to determine whether cardiac MRI(CMR) affords greater accuracy than echocardiography in establishing the diagnosis and assessing the magnitude of left ventricular(LV) hypertrophy in HCM. Methods and Results-Forty-eight patients(age 34±16 years) suspected of having HCM(or with a confirmed diagnosis) were imaged by both echocardiography and CMR to assess LV wall thickness in 8 anatomic segments(total n=384 segments) and compared in a blinded fashion. Maximum LV thickness was similar by echocardiography(21.7±9.1 mm) and CMR(22.5±9.6 mm; P=0.21). However, in 3(6%) of the 48 patients, echocardiography did not demonstrate LV hypertrophy, and CMR identified otherwise undetected areas of wall thickening in the anterolateral LV free wall(17 to 20 mm), which resulted in a new diagnosis of HCM. In the overall study group, compared with CMR, echocardiography also underestimated the magnitude of hypertrophy in the basal anterolateral free wall(by 20±6%; P=0001), as well as the presence of extreme LV wall thickness(≥30 mm) in 10%of patients(Pnclusions-CMR is capable of identifying regions of LV hypertrophy not readily recognized by echocardiography and was solely responsible for diagnosis of the HCM phenotype in an important minority of patients. CMR enhances the assessment of LV hypertrophy, particularly in the anterolateral LV free wall, and represents a powerful supplemental imaging test with distinct diagnostic advantages for selected HCM patients.

关键词：肥厚型心肌病心脏磁共振临床诊断磁共振成像二维超声心动图室壁厚度解剖断面标准检测肥厚程度 MR检查