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Epidemiology of Male Sexual Dysfunction (MSD) in Patients Consulting in Some Health Services in the City of Douala, Cameroon

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Open Journal of Epidemiology 2023年第4期13卷 436-448页

作者： Paul V. Mboumwa Modeste Wankeu-Nya théodore sala b.yemé Zacharie Nde Emma F. bend Frantz Ngalle Epoupa brice L. Koloko Sylvin b. Ateba Marie I. Ngaha Njila Paul Moundipa théophile Dimo Dieudonné Massoma Lembè Department of biology of Animal Organisms Faculty of Science University of Douala Douala Cameroon Department of Animal Production Faculty of Agronomy and Agricultural Sciences University of Dschang Dschang Cameroon Department of Urology of Laquintinie Hospital of Douala Douala Cameroon Department of biology and Physiology Faculty of Science University of Yaounde I Yaounde Cameroon

Sexual dysfunction is a group of diseases, disorders or difficulties experienced by men or women during any stage of normal sexual activity. In Africa in general and Cameroon in particular, statistical data concerning the prevelance and the main causes of male sexual dysfunction are rare due to socio-cultural and religious burdens and sometimes self-medication. the objective of this work was to determine the prevalences, comorbidities and the risk factors of the main sexual dysfunction in some hospitals in city of Douala. through a descriptive retrospective study carried out from Novembre 2019 to June 2021, sociodemographic parameter, reasons of consultation, risk factors and type of male sexual dysfunction (erectile dysfunction or erectile dysfunction (ED), ejaculation disorders (EjD), libido disorders (LD) and disorders of sexual activity with pain or painful sexual intercourse (PSI)) were collected in the medical files of patients who have made urological consultation between 2016 and 2020 at the Deido District hospital, Laquintinie Douala Hospital and Douala General hospital respectively. At the end of our data collection, out of a total of 24995 consultations, 2743 (10.98%) patients were suffering from at least one male sexual dysfunction. Moreover, sexual disorders were the 2nd reason of urological consultation (13.69%) after urinary disorders (33.85%). Among sexual disorders, erectile (76%) and ejaculatory (20%) disorders were the predominant pathologies recorded with the prevalences of 9.79 et 2.62% respectively, and were mostly represented in patients from [41 - 50] for erectile dysfunction, and [18 - 30] years old for ejaculative dysfunction. In addition, the number of patients with ejaculatory and erectile dysfunctions was more important in patients from [18 - 30] and [31 - 40] years old respectively. Among patients presenting sexual disorders, several risk factors or pathologies were associated with the dysfunction: benign prostatic hyperplasi

关键词： Male Sexual Dysfunction Patient Urologist Prevalence

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Epidemiology of Male Sexual Dysfunction (MSD) in Patients Consulting in Some Health Services in the City of Douala, Cameroon

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Open Journal of Epidemiology（流行病学期刊） 2023年第4期

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Advances in the development of new biomarkers for Alzheimer’s disease

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Translational Neurodegeneration 2022年第1期11卷 601-624页

作者： Timofey O.Klyucherev Pawel Olszewski Alena A.Shalimova Vladimir N.Chubarev Vadim V.Tarasov Misty M.Attwood Stina Syvänen Helgi b.Schiöth Department of Neuroscience Functional PharmacologyUniversity of Upp-salaUppsalaSweden Department of Pharmacology Institute of PharmacyI.M.Sechenov First Moscow State Medical UniversityMoscowRussia Institute of Translational Medicine and biotechnology I.M.Sechenov First Moscow State Medical UniversityMoscowRussia Department of Public Health and Caring Sciences Rudbeck LaboratoryUppsala UniversityUppsalaSweden.

Alzheimer’s disease(AD)is a complex,heterogeneous,progressive disease and is the most common type of neurodegenerative *** prevalence of AD is expected to increase as the population ages,placing an additional burden on national healthcare *** is a large need for new diagnostic tests that can detect AD at an early stage with high specificity at relatively low *** development of modern analytical diagnostic tools has made it possible to determine several biomarkers of AD with high specificity,including pathogenic proteins,markers of synaptic dysfunction,and markers of inflammation in the *** is a considerable potential in using microRNA(miRNA)as markers of AD,and diagnostic studies based on miRNA panels suggest that AD could potentially be determined with high accuracy for individual *** of the retina with improved methods of visualization of the fundus are also showing promising results for the potential diagnosis of the *** review focuses on the recent developments of blood,plasma,and ocular biomarkers for the diagnosis of AD.

关键词： Alzheimer’s disease Amyloid beta peptides biomarkers blood Cytokines Inflammation MicroRNA Ocular biomarkers

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