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Background diseases and the number of previous intravitreal aflibercept injections on immediate intraocular pressure increase and vitreous reflux rate in phakic eyes

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 545-550页

作者： tetsuya muto Shigeki Machida Shinichiro Imaizumi Department of Ophthalmology Dokkyo Medical University Saitama Medical CenterKoshigaya 343-8555Japan Imaizumi Eye Hospital Koriyama 963-8877Japan Fukushima Medical University Fukushima 960-1295Japan

●AIM:To evaluate the effect of background diseases and number of previous intravitreal aflibercept injections(IVAIs)on immediate intraocular pressure(IOP)increase and vitreous reflux(VR)rate and to evaluate the correlation of both age and axial length with immediate IOP increase and VR rate.●METHODS:This study included 105 patients with cystoid macular edema secondary to retinal vein occlusion,35 patients with diabetic macular edema,69 patients with neovascular age-related macular degeneration(nAMD),and 12 patients with myopic choroidal neovascularization,which underwent first-time *** correlation of immediate IOP increase and VR rates with the four background diseases was ***,the correlation of age with immediate IOP increase and VR rate as well as correlation of axial length with immediate IOP increase and VR rate were ***,54 patients with nAMD were treated with IVAI>10 times(multiple IVAIs).Moreover,the correlation of immediate IOP increase and VR rates with first-time and multiple IVAIs in nAMD was determined.●RESULTS:The immediate IOP increase(P=0.16)and VR rates(P=0.50)were almost similar among the four background *** immediate postinjection IOP and age,VR rate and age,immediate postinjection IOP and axial length,or VR rate and axial length were not correlated in the four background *** immediate IOP increase(P=0.66)and VR rates(P=0.28)did not significantly differ between first-time and multiple IVAIs in nAMD.●CONCLUSION:Background diseases and number of previous IVAIs have no effect on immediate IOP increase and VR ***,age and axial length have no correlation on immediate IOP increase and VR rate.

关键词： aflibercept intraocular pressure vitreous reflux intravitreal injection

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大尺度自成因机制与自成因地层学

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地质学报 2024年第7期98卷 1977-2000页

作者：王俊辉 Tetsuji muto 鲜本忠油气资源与工程全国重点实验室中国石油大学(北京)北京102249 中国石油大学(北京)地球科学学院北京102249 长崎大学环境科学部日本长崎852-8521

在海平面升降、构造活动、沉积物供给等外部驱动作用下,沉积地层的叠置受自成因和他成因两种机制的控制。近年的认识表明,自成因机制可发生在沉积过程的各个时空尺度。不同于小尺度自成因机制仅发生在沉积系统的局部,大尺度自成因机制... 详细信息

在海平面升降、构造活动、沉积物供给等外部驱动作用下,沉积地层的叠置受自成因和他成因两种机制的控制。近年的认识表明,自成因机制可发生在沉积过程的各个时空尺度。不同于小尺度自成因机制仅发生在沉积系统的局部,大尺度自成因机制可在盆地范围内系统性地控制地层的发育,能够修饰甚至改变他成因过程。要想准确地探究地层的叠置样式与外部驱动条件之间的关系,必须有效地鉴别大尺度自成因与他成因过程。基于对大尺度自成因过程的认识,逐渐建立与发展了自成因地层学。它提出的自成因与他成因观、平衡响应与非平衡响应观为解析地层叠置样式与外部驱动条件之间的关系提供了新的视角。自成因地层学一方面对外部驱动条件分为稳定的(速率等作用方式保持不变)与不稳定的(速率等作用方式发生改变),由前者形成的地层叠加样式(或过程)称为自成因的,后者形成的地层叠加样式(或过程)称为他成因的。另一方面也将地层叠置样式分为稳定的(加积速率与进积速率的比值R_(agg)/R_(pro)保持不变)与不稳定的(R_(agg)/R_(pro)发生改变)。若稳定的外部驱动条件形成稳定的地层叠加样式,称为平衡响应,是自成因过程;稳定的外部驱动条件形成不稳定的地层叠加样式称为自成因的非平衡响应。此外,不稳定的外部驱动条件也可能形成稳定的地层叠加样式,称为他成因的非平衡响应。自成因地层学认为,由于自成因非平衡响应机制的普遍存在,地层的叠加过程通常表现得不稳定。相比而言,稳定的地层叠加样式仅在特殊情况下才能发生。传统成因地层学应当重视大尺度的自成因机制。

关键词：自成因地层学自成因与他成因平衡响应与非平衡响应海岸线自动后退三角洲海侵与非三角洲海侵基准面

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Prototyping of Ultra Micro Centrifugal Compressor-Influence of Meridional Configuration

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Journal of Thermal Science 2011年第4期20卷 312-317页

作者： Toshiyuki Hirano Tadataka muto Hoshio Tsujita Production Systems Engineering Course Tokyo Metropolitan College of Industrial Technology Graduate School of Engineering Hosei University3-7-2KajinochoKoganei-shiTokyo184-8584Japan Department of Mechanical Engineering Faculty of Science and EngineeringHosei University

In order to investigate the design method for a micro centrifugal compressor, which is the most important component of an ultra micro gas turbine, two types of centrifugal impeller with 2-dimensional blade were designed, manufactured and tested. These impellers have different shapes of hub on the meridional plane with each other. Moreover, these types of impeller were made for the 5 times and the 6 times size of the final target centrifugal impeller with the outer diameter of 4ram in order to assess the similitude for the impellers. The comparison among the performance characteristics of the impellers revealed the influence of the meridional configuration on the performance and the similitude of the compressors.

关键词： Ultra Micro Centrifugal Compressor Performance Characteristics Impeller Meridional Configuration

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Fabrication of a model specimen for understanding micro-galvanic corrosion at the boundary ofα-Mg andβ-Mg17Al12

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Journal of Magnesium and Alloys 2023年第1期11卷 137-153页

作者： Zheng Shao Masashi Nishimoto Izumi muto Yu Sugawara Department of Materials Science Graduate School of EngineeringTohoku University6-6-02 Aza-AobaAramakiAoba-kuSendai 980-0579Japan

A model specimen with a single boundary of theα/βphase simulating Mg-Al alloys was successfully fabricated by spark plasma sintering.A small electrode area ofαphase orβphase was prepared using the model specimen,and the OCPs(open-circuit potentials)of each phase and a small electrode area containing theα/βphase boundary in 0.1 M NaCl at pH 8.0 were compared:theβphase exhibited a higher potential,and theαphase showed a lower *** OCP of the small area containing theα/βphase boundary was the intermediate value of these *** a small area containingα/βphase boundary,discoloration and gas bubbles were observed on theαphase,but no bubble generation was detected on theβ*** gas bubbles were initially generated on theαphase near theβphase,but as the discoloration(corrosion)of theαphase approached theβphase,the bubbles were generated on theβ*** micro-galvanic corrosion of theαandβphases,theβphase did not always function as the preferred ***αphase partially corroded(or discolored)and became the anodes,so that the surrounding areas were most likely to be the *** corroded areas(anodes)in theαphase approached theβphase,theβphase would become *** addition to the micro-galvanic corrosion mechanism,the role of Al in corrosion resistance at theα/βphase boundary was determined by surface analysis.

关键词： Magnesium alloy α/βphase boundary Micro-scale observation technique Micro-galvanic corrosion Spark plasma sintering

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Fabrication of Shape-Controlled Au Nanoparticles in a TiO_2-Containing Mesoporous Template Using UV Irradiation and Their Shape-Dependent Photocatalysis

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Journal of Materials Science & Technology 2014年第1期30卷 8-12页

作者： Teruhisa Okuno Go Kawamura Hiroyuki muto Atsunori Matsuda Department of Environmental and Life Sciences Toyohashi University of Technology Department of Electrical and Electronic Information Engineering Toyohashi University of Technology

A SiO2-TiO2 template with ordered tubular mesochannels has been prepared by the sol-gel method. Au nanorods are deposited in the tubular mesochannels of the SiO2-TiO2 template, and the shape of Au is changed from nanorods to nanospheres by ultraviolet irradiation during thermal deposition. The photocatalytic activity of mesoporous SiO2-TiO2 with/without Au nanorods/nanospheres is evaluated. Deposition of Au in the mesoporous SiO2-TiO2 template enhances the photocatalysis of TiO2. Interestingly, the sample containing Au nanorods exhibits higher photocatalytic activity than that with Au nanospheres. Photocatalysis by exciting surface plasmon resonance is not detected in the composite samples regardless of the shape of the deposited Au nanoparticles.

关键词： Mesoporous Titania Gold Shape control Photocatalysis Surface plasmon resonance

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Study on Shock Wave and Turbulent Boundary Layer Interactions in a Square Duct at Mach 2 and 4

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Journal of Thermal Science 2006年第1期15卷 37-42页

作者： Hiromu SUGIYAMA Ryojiro MINATO Kazuhide MIZOBATA Akira TOJO Yohei muto Department of Mechanical Systems Engineering Muroran Institute of Technology 27-1 Mizumoto Muroran Hokkaido 050-8585 Japan Graduate School Muroran Institute of Technology

In this paper, the outline of the Mach 4 supersonic wind tunnel for the investigation of the supersonic internal flows in ducts was firstly described. Secondly, the location, structure and characteristics of the Mach 2 and Mach 4 pseudo-shock waves in a square duct were investigated by color schlieren photographs and duct wall pressure fluctuation measurements. Finally, the wall shear stress distributions on the side, top and bottom walls of the square duct with the Mach 4 pseudo-shock wave were investigated qualitatively by the shear stress-sensitive liquid crystal visualization method. The side wall boundary layer separation region under the first shock is narrow near the top wall, while the side wall boundary layer separation region under the first shock is very wide near the bottom wall.

关键词： supersonic internal flow pseudo-shock wave flow visualization shear stress-sensitive liquid crystal.

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Rebalancing China's Economic Growth:Some Insights from Japan's Experience

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China & World Economy 2012年第1期20卷 62-82页

作者： Tomoyuki Fukumoto Ichiro muto Associate Director-General International DepartmentBank of JapanTokyoJapan. Director Research and Statistics DepartmentBank of JapanTokyoJapan.

One of the greatest challenges China faces is reshaping its heavily investment-driven mode of economic growth. By investigating how the rebalancing of Japan＇s economic growth mode was realized in the 1970s, we indicate that it is essential in rebalancing to correct the distortions in factor cost （labor cost and capital cost） in a harmonious way. In addition, we refer to Japan＇s experience to indicate that rebalancing of domestic growth does not necessarily lead to external rebalancing.

关键词： China current account imbalance factor cost distortion Japan rebalancing

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Seismotectonics of Southern Calabria Terrane(South Italy)

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Journal of Mountain Science 2022年第11期19卷 3148-3162页

作者： Vincenzo TRIPODI Anna GERVASI Mario LA ROCCA Federica LUCA Francesco muto National Research Council of Italy(CNR)—Research Institute for Geo-Hydrological Protection(IRPI) Rende 87036Italy National Institute of Geophysics and Volcanology(INGV) National Earthquake Observatory SectionRoma 00143Italy Department of Biology Ecology and Earth Science(DiBEST)University of CalabriaRende 87036Italy

Seismic data of earthquakes recorded during the last 40 years in southern Calabria have been compared with geological data in order to obtain a seismotectonic picture of the area. We sought for any possible correlation between the main regional tectonic structures, the distribution of earthquake hypocentres and the focal mechanism of earthquakes with magnitude(Ml)≥*** of historical and recent seismicity and analysis of geological structures allowed to define the main shear strips on a regional scale. More than 2600 earthquakes with 1.5 ≤ Ml ≤ 4.5 have been considered. The focal mechanisms of earthquakes with Ml≥3 have been compared with the kinematics of known faults and used to give insight on the current active stress field. From the analysis carried out it was possible to expand the cognitive framework regarding the activity of the main tectonic structures present in the area. This study also served to identify areas of high seismicity which do not correspond to any evidence of tectonic structures on the surface, and areas where recognized tectonic structures have not shown any seismicity during the last decades. These cases could be the subject of future investigation in order to correctly assess the seismic hazard in *** task is important in the context of seismic hazard evaluation and mitigation.

关键词： Calabria Seismicity Tectonics Earthquakes

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Assessment of KL-6 as a tumor marker in patients with hepatocellular carcinoma

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World Journal of Gastroenterology 2005年第42期11卷 6607-6612页

作者： Amal Gad Eiji Tanaka Akihiro Matsumoto Moushira Abd-el Wahab Abd el-Hamid Serwah Fawzy Attia Khalil Ali Howayda Hassouba Abd el-Raoof el-Deeb tetsuya Ichijyo Takeji Umemura Hidetomo muto Kaname Yoshizawa Kendo Kiyosawa Second Department of Internal Medicine Shinshu University School of Medicine Matsumoto Japan Howayda Hassouba Abd el-Raoof el-Deeb Suez Canal University School of Medicine Ismailia Egypt Second Department of Internal Medicine Shinshu University School of Medicine Matsumoto Japan Howayda Hassouba Abd el-Raoof el-Deeb Suez Canal University School of Medicine Ismailia Egypt Shinshu University Graduate School of Medicine Institutes of Organ Transplants Reconstructive Medicine and Tissue Engineering Matsumoto Japan

AIM： To investigate the clinical significance of KL-6 as a tumor marker of HCC in two different ethnic groups with chronic liver disease consecutively encountered at outpatient clinics. METHODS： Serum KL-6 was measured by the sandwich enzyme immunoassay method using the KL-6 antibody （Ab） as both the capture and tracer Ab according to the manufacturer＇s instructions （Eisai, Tokyo, Japan）. Assessment of alpha fetoprotein （AFP） and protein induced vitamin K deficiency or absence （PIVKA-II） was performed in both groups using commercially available kits. RESULTS： A significantly higher mean serum KL-6 （556±467 U/L） was found in HCC in comparison with non-HCC groups either with （391±176 U/L; P〈0.001） or without （361±161 U/L; P〈0.001） liver cirrhosis （LC）. Serum KL-6 level did not correlate with either AFP or PIVKA-II serU/Levels. Using rec：eiver operating curve analysis for KL-6 as a predictor for HCC showed that the area under the curve was 0.574 （95%CI = 0.50-0.64） and the KL-6 level that gave the best sensitivity （61%） was found to be 334 U/L but according to the manufacturer＇s instructions; a cut-off point of 500 U/L was used that showed the highest specificity （80%） in comparison with AFP and PIVKA-II （78% vs 72% respectively）. Combining the values of the three markersimproved specificity of AFP for HCC diagnosis from 78% for AFP alone; 93% for AFP plus PIVKA-II to 99% for both plus KL-6 value （P〈0.001）. Mean serum alkaline phosphatase level was significantly higher in KL-6 positive （564＋475） in comparison with KL-6 negative （505＋469） HCC patients （P = 0.021）, but such a difference was not found among non-HCC corresponding groups. CONCLUSION： KL-6 is suggested as a tumor for HCC. Its positivity may reflect HCC-associated cholestasis and/ or local tumor invasion.

关键词： Tumor markers Liver disease Hepatocellularcarcinoma

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Is rectal cancer prone to metastasize to lymph nodes than colon cancer?

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World Journal of Gastroenterology 2011年第29期17卷 3465-3466页

作者： Takashi Akiyoshi Toshiaki Watanabe Masashi Ueno Tetsuichiro muto Gastroenterological Center Department of Gastroenterological SurgeryCancer Institute HospitalJapanese Foundation for Cancer ResearchTokyo 135-8550Japan Department of Surgery Teikyo University School of MedicineTokyo 173-8605Japan

The biology of colorectal cancer differs according to its location within the large intestine.A report published in a previous issue of World Journal of Gastroenterology (November 2010) evaluated the importance of tumor location as a risk factor for lymph node metastasis in colorectal cancer,and showed that rectal cancer is prone to metastasize to lymph nodes as compared with colon ***,in order to conclude that the tumor location is independently associated with the occurrence of lymph node metastasis,it is necessary to consider a selection bias or other patientand tumorrelated factors carefully.

关键词： Rectum Colon Lymph node Metastasis Cancer

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