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Simultaneous Multimode Oscillation of Stress-Compensated Cut Quartz Resonator with Narrow-Band Wide Variable-Range Quartz Crystal Oscillator

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Engineering（科研） 2014年第13期6卷 973-988页

作者： Tomio Sato tetsuya akitsu Division of Human Environmental and Medical Engineering Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi Kofu Japan

A multimode-quartz-crystal oscillator was developed to excite stable dual-mode resonance at different frequencies: The oscillation of the 3rd harmonic resonance of the principle C-mode and an additional resonance B-mode of SC-cut crystal. Harmonic combinations of the 3rd and fundamental mode of B-mode with the 3rd harmonics of C-mode are demonstrated. The measurement of the temperature dependence of the oscillation frequency is demonstrated along with the stability determined by root Allan variance. Dependence on the open conductance of the active circuit and the dependence on the coupling capacitors are discussed.

关键词： Temperature Sensing Piezoelectric Sensor Dual-Mode Quartz Crystal Resonance Stress-Compensated Cut (SC-Cut)

Material Conformity and Bactericidal Characteristics of High-Density Ozone Disinfection in Vinyl Polysiloxane Impression and PMMA Dentistry Fillings

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Engineering（科研） 2014年第7期6卷 319-328页

作者： Hiroshi Ohkawa tetsuya akitsu Division of Human Environmental and Medical Engineering Interdisciplinary Graduate School of Medicine and Engineering National University of Yamanashi Kofu Japan Plasma Division Yamato Science Co. Ltd. Minami-Alps City Japan

Disinfection was investigated in high-density ozone produced by dielectric barrier discharge under atmospheric pressure. Disinfection was studied on three-dimensional carriers made of hydrophilic vinyl-polysiloxane impression material and granular acrylic resin used for oral surgery. Experimental results indicate disinfection of spore-forming bacteria: Geobacillus stearothermophilus and Bacillus atrophaeus, and selected species of opportunistic pathogens: Aspergillus niger, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, and Candida albicans.

关键词： Ozone Disinfection Bacillus atrophaeus Geobacillus stearothermophil Aspergillus niger Pseudomonas aeruginosa Escherichia coli Staphylococcus aureus Candida albicans

Compatibility of the Active Inductance Double Resonance Quartz Oscillator with Q-MEMS Temperature Sensor

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Engineering（科研） 2015年第2期7卷 47-57页

作者： tetsuya akitsu Akira Kudo Tomio Sato Human Environment and Medical Engineering Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi Takeda 4-3-11 Kofu Japan SEIKO EPSON Corporation Head-Quarter Owa 3-3-5 Suwa Japan

Low-frequency double-resonance quartz crystal oscillator circuit was developed with active inductance aiming the quick start-up in the intermittent operation on the sensor circuit and DC isolation using a Q-MEMS sensing crystal HTS-206. Allan standard deviation indicated 5 × 10–12, showing short range stability of the sensor circuit sufficient for the ubiquitous environmental sen sor network.

关键词： Q-MEMS Sensing Crystal HTS-206 Active Inductance Double Resonance

Start-Up Acceleration of Quartz Crystal Oscillator Using Active Inductance Double Resonance and Embedded Triggering Circuit

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Journal of Sensor Technology 2015年第1期5卷 15-27页

作者： Tomio Sato Akira Kudo tetsuya akitsu Department of Human Environment and Medical Engineering Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi Kofu Japan SEIKO EPSON Corporation Suwa Japan

Low-frequency double-resonance quartz crystal oscillator was developed with active inductance circuit aiming the start-up of stable oscillation of tuning fork-type quartz crystal resonator at 32.768 kHz within 0.37 ms. The initial oscillation is triggered by a part of crystal oscillator forming a CR oscillator. The negative resistance ranges to 4 MΩ at gmf of 4.1 μA/V. In a limited frequency range, the circuit shows negative reactance Ccci = -3.4 pF equivalent to inductance Lcc = 9.8 H. The Allan standard deviation indicated 10-11 to 10-10, showing high stability comparable to general quartz crystal oscillator.

关键词： Double Resonance Quartz Crystal Oscillator Active Inductance

Anti-aquaporin-4 antibody(AQP4-IgG)and anti-myelin oligodendrocyte glycoprotein antibody(MOG-IgG)in the cerebrospinal fluid

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Neural Regeneration Research 2024年第5期19卷 949-950页

作者： tetsuya Akaishi Tatsuro Misu Department of Neurology Tohoku UniversitySendaiJapan

In the last decade,a new neurological disease concept known as anti-myelin oligodendrocyte glycoprotein antibody(MOG-IgG)-associated disease(MOGAD)has emerged and is currently one of the most focused research areas in the field of *** is a membrane protein mainly expressed on the surface of oligodendrocytes(Zhou et al.,2006).The exact pathogenic role of MOG-IgG in patients with MOGAD remains unclear;however,MOG-IgG has been suggested to cause tissue alterations and damage MOG-expressing cells(Zhou et al.,2006).The pathogenicity of MOG-IgG is further supported by the observation that only a few patients with acquired central nervous system(CNS)demyelinating syndromes exhibit both anti-aquaporin-4 antibody(AQP4-IgG)and MOG-IgG simultaneously,particularly with clear positivity levels of these antibodies as indicated by a cell-based assay result with a titer≥1:100(Sechi et al.,2021;Banwell et al.,2023).

关键词： AQP4 myelin

Statistical evaluation of cluster formation of relapse in neuromyelitis optica spectrum disorder

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Neural Regeneration Research 2024年第9期19卷 1888-1889页

作者： tetsuya Akaishi Ichiro Nakashima Department of Neurology Tohoku UniversitySendaiJapan Department of Neurology Tohoku Medical and Pharmaceutical UniversitySendaiJapan

Evaluating the cluster formation of clinical attacks in chronic relapsing diseases is an important statistical issue because the presence of attack clusters may influence therapeutic strategies for relapse *** recently reported the occurrence of unevenly clustered attacks in patients with anti-aquaporin-4(AQP4)antibody-positive neuromyelitis optica spectrum disorder(NMOSD)(Akaishi et al.,2020a).

关键词： AQP4 relapse

Degradation of Aqueous 2,6-Dibromophenol Solution by In-Liquid Dielectric Barrier Microplasma

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World Journal of Engineering and Technology 2016年第3期4卷 423-432页

作者： Shin-Ichiro Kojima Keiko Katayama-Hirayama tetsuya akitsu Department of Advanced Energy Engineering Science Kyushu University Kasuga Japan Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi Kofu Japan

Degradation of 2,6-dibromophenol (2,6-DBP) in the aqueous solution was studied using dielectric barrier discharge in micro-bubbles. Experimental comparison of working gas Ar, N2, O2, and air showed that oxygen and air plasma efficiently decomposed 2,6-DBP to bromide ion, and inorganic carbon. The molecular orbital model was applied in the analysis of the degradation in electrophilic, nucleophilic, and radical reactions.

关键词： 2 6-Dibromophenol Atmospheric Pressure Plasma Inductive Energy-Storage System

Background diseases and the number of previous intravitreal aflibercept injections on immediate intraocular pressure increase and vitreous reflux rate in phakic eyes

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 545-550页

作者： tetsuya Muto Shigeki Machida Shinichiro Imaizumi Department of Ophthalmology Dokkyo Medical University Saitama Medical CenterKoshigaya 343-8555Japan Imaizumi Eye Hospital Koriyama 963-8877Japan Fukushima Medical University Fukushima 960-1295Japan

●AIM:To evaluate the effect of background diseases and number of previous intravitreal aflibercept injections(IVAIs)on immediate intraocular pressure(IOP)increase and vitreous reflux(VR)rate and to evaluate the correlation of both age and axial length with immediate IOP increase and VR rate.●METHODS:This study included 105 patients with cystoid macular edema secondary to retinal vein occlusion,35 patients with diabetic macular edema,69 patients with neovascular age-related macular degeneration(nAMD),and 12 patients with myopic choroidal neovascularization,which underwent first-time *** correlation of immediate IOP increase and VR rates with the four background diseases was ***,the correlation of age with immediate IOP increase and VR rate as well as correlation of axial length with immediate IOP increase and VR rate were ***,54 patients with nAMD were treated with IVAI>10 times(multiple IVAIs).Moreover,the correlation of immediate IOP increase and VR rates with first-time and multiple IVAIs in nAMD was determined.●RESULTS:The immediate IOP increase(P=0.16)and VR rates(P=0.50)were almost similar among the four background *** immediate postinjection IOP and age,VR rate and age,immediate postinjection IOP and axial length,or VR rate and axial length were not correlated in the four background *** immediate IOP increase(P=0.66)and VR rates(P=0.28)did not significantly differ between first-time and multiple IVAIs in nAMD.●CONCLUSION:Background diseases and number of previous IVAIs have no effect on immediate IOP increase and VR ***,age and axial length have no correlation on immediate IOP increase and VR rate.

关键词： aflibercept intraocular pressure vitreous reflux intravitreal injection

Plasma-Electrolysis of Dinitrophenol in Gas-Liquid Boundary and Interpretation Using Molecular Orbital Theory

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World Journal of Engineering and Technology 2019年第1期7卷 141-157页

作者： Hiroshi Okawa Hiroki Kuroda Keiko Hirayama-Katayama Shin-Ichiro Kojima tetsuya akitsu Happy Science University Chosei-Chiba Japan University of Yamanashi Kofu Japan Kyushu University Fukuoka Japan

The advanced oxidation of 2,4-dinitrophenol (DNP), 2,5-DNP, and 3,4-DNP in aqueous solution has been investigated using a multi-gas, dielectric barrier discharge. Dielectric barrier discharge was operated in the aqueous solution and gas boundary. The degradation was measured by high performance liquid chromatography (HPLC). The acceleration of the advanced-oxidation has been investigated by the combination of the anion exchange polymer membrane. The result indicated that the degradation pathways involve a rapid detachment of the nitro group and a slow opening of the aromatic-ring. The hydroxyl radical and the excited hydroxyl anion are responsible for the primary attack of the DNP with the production of dihydroxy-nitrobenzenes. The attack of hydroxyl radical occurs at the benzene ring carbon activated by the presence of a phenolic OH group and a nitro group. The result suggested that the reaction is dominated by a pseudo-first order kinetic reaction. The degradation process is interpreted using Molecular Orbital Theory.

关键词： Dielectric Barrier Discharge Dinitrophenol Advanced Oxidation Molecular Orbital Theory