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Memory deficits in mild traumatic brain injury

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中华物理医学与康复杂志 2017年第3期39卷 201-201页

作者： Wammes jd Good TJ Fernandes MA

BACKGROUND AND OBJECTIVE The detrimental consequences of mild traumatic brain injury (mTBI) are becoming more apparent in a number of different cognitive domains. This study reviewed the long-term effects of mTBI one year or more *** Undergraduate students were recruited from psychology classes at the University of Waterloo in Ontario, Canada, with older adults recruited from the Waterloo Research in Aging Participant Pool (WRAP). Of the 39 students recruited 20 reported a remote mTBI, and of the 42 older adults recruited, 20 reported a mTBI. Those with and those without remote mTBI were compared by performance on a series of neuropsychological *** As the mean intervening time since mTBI in the older adults was 38 years, the analysis was completed first with both groups combined, and then with only the younger group. Within the older group, no significant differences were observed based on mTBI status. In the younger group, those with a history of mTBI performed more poorly than did those without mTBI on free recall (P<0.05), as well as when recounting autobiographical memories (P<0.01).CONCLUSION This study of individuals with remote mTBI suggests that these individuals, despite having otherwise normal cognitive test results, may have a specific pattern of cognitive deficits characterized by a decreased ability in free recall and reduced episodic detail when recounting autobiographical memories.

关键词：创伤性脑损伤记忆障碍认知领域

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武器内部构件对高速撞击的动态响应

核武器与高技术 1997年第4期 33-39页

作者： Gruda,jd

武器内部构件对事故的动态响应，对于确定武器安全性至关重要本研究的主要目的是，以安全构件的过载历程为基础确定武器安全性。事故情况是武器以每秒８０英尺的速度撞击铁路轨道。由于撞击条件的严重性，预测有大变形和许多接触。该分... 详细信息

武器内部构件对事故的动态响应，对于确定武器安全性至关重要本研究的主要目的是，以安全构件的过载历程为基础确定武器安全性。事故情况是武器以每秒８０英尺的速度撞击铁路轨道。由于撞击条件的严重性，预测有大变形和许多接触。该分析的复杂性要求能够同时跟踪多个接触面和利用单元死亡法模拟材料失效的非线性有限元编码。

关键词：核武器内部构件安全性高速撞击动态响应

Romosozumab for osteoporosis

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中华物理医学与康复杂志 2016年第12期38卷 915-915页

作者： Cosman F Crittenden DB Adachi jd

BACKGROUND AND OBJECTIVE Even after fracture,fewer than 25%of patients receive pharmacologic treatment for *** the discovery that sclerostin deficiency causes rare genetic conditions that are characterized by high bone mass and resistance to fracture,sclerostin has become a therapeutic target for the treatment of this *** study assessed the effect of romosozumab,a monoclonal antibody that binds and inhibits sclerostin with the dual effect of increasing bone formation and decreasing bone *** Subjects were ambulatory,postmenopausal women,55 to 90 years of age,with T scores at the total hip or femoral neck of-

关键词：骨质疏松症药物治疗单克隆抗体遗传性骨吸收骨形成骨折

一氧化氮——一种特异性肺血管舒张剂研究进展及展望

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国外医学（麻醉学与复苏分册） 1993年第3期14卷 129-132页

作者：熊利泽 Young jd 曾祥龙第四军医大学西京医院麻醉科 Nuffield Department of Anaesthetics University of Oxford UK.

一氧化氮是一种有害气体.低浓度吸入后可经肺泡弥散于肺血管平滑肌内,从而舒张肺循环血管.弥散于血流的一氧化氮,直接与血红蛋白结合,转化成高铁血红蛋白,使之失活.研究表明,吸入低浓度一氧化氮,可不同程度地降低肺动脉高压.在吸入一氧... 详细信息

一氧化氮是一种有害气体.低浓度吸入后可经肺泡弥散于肺血管平滑肌内,从而舒张肺循环血管.弥散于血流的一氧化氮,直接与血红蛋白结合,转化成高铁血红蛋白,使之失活.研究表明,吸入低浓度一氧化氮,可不同程度地降低肺动脉高压.在吸入一氧化氮浓度低于100ppm下,未发现有明显的毒副作用.本文就其研究历史,吸入一氧化氮对肺动脉高压的作用,其选择性作用于肺循环的机理、毒副作用、吸入方法等进行了回顾,并简要地提出尚需解决的问题.一氧化氮可能会成为真正特异性肺血管舒张剂.

关键词：血管扩张药肺一氧化氮研究远景