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世界核心医学期刊文摘（儿科学分册） 2006年第8期2卷 48-49页

作者： kitano Y. Matsuoka K. Honna T. 贺莉 Division of General Surgery National Center for Child Health and DevelopmentSetagaya-kuTokyo 157-8535Japan

Background/Purpose:Fetal extralobar pulmonary sequestration(EPS)is sometime s complicated by massive pleural effusion(PE)leading to fetal *** und erlying mechanisms as well as the origin of the fluid are not well understood.T his study was performed to find a histological hallmark of an EPS with massive P *** hypothesized that venous obstruction has a role to play in the mechanisms of fluid production by ***:We recently experienced 3 cases of fetal EP S complicated by fetal hydrothoraxrequiring thoracentesis and eventually thoraco amniotic shunt *** protein content and cell count were measured in the aspirates,which were compared with chylothorax cases(n = 5)requiring feta l shunt *** birth,all 3 infants required mass resection for the co ntrol of *** venous wall thickness was measured on pathology slides stained with Elastica van Gieson *** of the media and adventitia was mea sured in approximately 40 veins per *** were corrected by external diamet er and expressed as percentage of medial thickness and percentage of adventitial *** EPS not associated with PE but with congenital diaphragmatic hern ia served as a ***:Total protein and the cell count of the EPS rel ated PE were 0.6 ±0.3 mg/dL and 28 ±14/μL(mean ±SD),which were significantly lower than those of PE i n chylothorax(2.2 ±0.2 mg/dL and 1900 ±1100/μL).Percentages of adventitial thickness of EPS with PE were 9.8%±3.8%,10.4%±3.6%,and 8.3%±3.7%,whi ch were significantly increased compared with the control of 3.1%±1.3%(P < 0.01).Percentages of medial thickness of EPS with PE were 7.0%±1.9%,7.3%±1.4%,and 6.6%±2.3%,which were significantly increased compared with the cont rol of 2.3%±0.7%(P< 0.01).Conclusions:We conclude that PE associated with EPS is the transudate rather than the *** thickened media and the adventi tia found in EPS with PE support the hypothesis that partial obstruction of the venous system leads to an i

关键词：肺叶外型肺隔离症静脉动脉化胎儿水肿患儿胸膜腔积液胸腔穿刺术先天性膈疝 EPS 静脉阻塞胸腔积液

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高镁埃达克岩和低钙玻安岩的成因岩石学解析

高镁埃达克岩和低钙玻安岩的成因岩石学解析

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2014年中国地球科学联合学术年会——专题31：俯冲带壳幔相互作用

作者：李毅兵 Jun-Ichi Kimura Shiki Machida teruaki Ishii 中国地质科学院地质研究所

伊豆-小笠原-马里亚纳岛弧出露有太平洋板块向菲利宾海板块俯冲的最初期阶段产生的岛弧高镁安山岩-玻安岩(48-44 Ma)。东京大学大气海洋研究所经过多次航海调查和海底取样后,在小笠原前弧海山采取了大量的火山岩,深成岩和橄榄岩。火山...

伊豆-小笠原-马里亚纳岛弧出露有太平洋板块向菲利宾海板块俯冲的最初期阶段产生的岛弧高镁安山岩-玻安岩(48-44 Ma)。东京大学大气海洋研究所经过多次航海调查和海底取样后,在小笠原前弧海山采取了大量的火山岩,深成岩和橄榄岩。火山岩包括有玻安岩,并且首次采集到高镁埃达克火山岩。全岩40Ar/39Ar年代显示高镁埃达克岩具有和玻安岩相近或者比玻安岩稍微年轻的地质年代(43-

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Factors associating with oxygenation of lower-limb muscle tissue in hemodialysis patients

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World Journal of Nephrology 2016年第6期5卷 524-530页

作者： Haruhisa Miyazawa Susumu Ookawara Kiyonori Ito Katsunori Yanai Hiroki Ishii Taisuke kitano Mitsutoshi Shindo Yuichiro Ueda Yoshio Kaku Keiji Hirai Taro Hoshino Kaoru Tabei Yoshiyuki Morishita Division of Nephrology First Department of Integrated Medicine Saitama Medical Center Jichi Medical University Department of Internal Medicine Minami-uonuma City Hospital

AIM To evaluate the lower-limb muscle oxygenation in hemodialysis(HD) patients and identify the factors associating with muscle *** Sixty-seven HD patients(53 men and 14 women; mean age, 67.1 ± 1.2 years; mean HD duration, 5.6 ± 0.9 years) were recruited. In addition, 15 healthy individuals(nine men and six women; mean age, 38.2 ± 4.6 years) were recruited as the control group. Lower-limb muscle regional saturation of oxygen(rS O_2) was monitored on the lateral side of the gastrocnemius muscle before HD using an INVOS 5100C(Covidien Japan, Tokyo, Japan), which utilizes near-infrared spectroscopy. Here, we evaluated the association between lower-limb muscle rS O_2 and clinical *** The r SO_2 values were significantly lower in patients undergoing HD than in healthy individuals(50.0%± 1.7% vs 76.8% ± 2.5%, P < 0.001). Lower-limb muscle r SO_2 showed significant positive correlations with diastolic blood pressure, blood urea nitrogen concentration, serum creatinine concentration, serum potassium concentration, serum inorganic phosphate concentration, and serum albumin concentration as well as negative correlation with HD duration. We conducted a multiple linear regression analysis using parameters that were significantly correlated with the lower-limb muscle r SO_2 in a simple linear regression analysis. Multiple regression analysis demonstrated that lowerlimb muscle r SO_2 was independently associated with serum inorganic phosphate(standardized coefficient: 0.27) and serum albumin concentrations(standardized coefficient: 0.24). In addition, there were no differences in lower-limb muscle r SO_2 between diabetic and nondiabetic HD patients. This study has several limitations. Firstly, its sample size was relatively small. Secondly, we could not evaluate the association between lowerlimb muscle r SO_2 and calculated nutritional markers, including normalized protein catabolic rate and body mass index, anthropometric measurements representing

关键词： Regional saturation of oxygen Lower-limb muscle Sarcopenia Protein-energy wasting Nutritional status Inorganic phosphate Albumin Hemodialysis

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日本稻米价格与收入补贴政策的演进过程及战略创新

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中国农业大学学报（社会科学版） 2018年第1期35卷 89-99页

作者：李东坡南石晃明长命洋佑日本九州大学日本九州大学农业资源经济系日本农业信息学会

作为经济成长战略的组成部分,日本政府决定依靠提升竞争力和开拓市场,大幅度增加农业收入。水稻是最主要的粮食作物,对其限产保护和主食用稻米的生产补贴将于2018年取消。日本水稻生产经营以小规模农户为主,对价格保护和收入补贴有较强... 详细信息

作为经济成长战略的组成部分,日本政府决定依靠提升竞争力和开拓市场,大幅度增加农业收入。水稻是最主要的粮食作物,对其限产保护和主食用稻米的生产补贴将于2018年取消。日本水稻生产经营以小规模农户为主,对价格保护和收入补贴有较强依赖性,相关政策调整备受关注。本文系统梳理了日本稻米价格和收入补贴政策的演进过程,以及新形势下的战略创新。发端于"二战"前的价格管制在稳定粮荒时代稻米供求的同时,也带来了沉重的财政负担。随着供求关系的变化和相关法律的调整,粮食流通市场逐渐开放,以市场为基础的稻米价格形成机制确立。从1990年代末开始,受农业经济形势特别是世贸组织规则的限制,日本政府更多依靠收入补贴缓解价格下降对农业生产的冲击。伴随政党更替,补贴对象和标准几经修改。自民党政府侧重于促进生产资源向高效、可持续的农业经营体集中,民主党政府则更多考虑小规模农户的生产成本补偿。为化解稻米供给量反弹压力,补贴的重点已经转向饲料和加工等新用途稻米,并且正在努力升级为农业保险。

关键词：稻米价格日本收入补贴政策

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北野武自述

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作者： (日)北野武(Takeshi kitano) (法)米歇尔·特曼(Michel Temman)

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手术期间血糖控制对糖尿病视网膜病变和黄斑病变的影响

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美国医学会眼科杂志（中文版） 2006年第4期18卷 254-255页

作者： Chikako Suto Sadao Hori SatoshI Kato Kanemitsu Muraoka Shigehiko kitano 刘亮（译）

目的：评估手术期间血糖控制对糖尿病视网膜病变和黄斑病变进展的影响。

关键词：糖尿病视网膜病变黄斑病变血糖控制手术期间

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连铸和热轧同步的无缺陷浇铸技术

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浙江冶金 2000年第4期 4-8页

作者： Y.kitano H.Take H.Tozawa 吕杏春杭州钢铁集团公司技术处杭州310022

1 前言日本川崎钢铁公司千叶厂3号连铸机月产板坯20万 t,大部分用于汽车及罐头生产。建于1995年的第三热轧厂采用直接热装系统(DHCR),可以将切割后的板坯在7 min

关键词：板坯连铸连铸机热轧无缺陷浇铸技术

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Familial pancreatic cancer: Concept, management and issues

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World Journal of Gastroenterology 2017年第6期23卷 935-948页

作者： Hiroyuki Matsubayashi Kyoichi Takaori Chigusa Morizane Hiroyuki Maguchi Masamichi Mizuma Hideaki Takahashi Keita Wada Hiroko Hosoi Shinichi Yachida Masami Suzuki Risa Usui Toru Furukawa Junji Furuse Takamitsu Sato Makoto Ueno Yoshimi Kiyozumi Susumu Hijioka Nobumasa Mizuno Takeshi Terashima Masaki Mizumoto Yuzo Kodama Masako Torishima Takahisa Kawaguchi Reiko Ashida Masayuki kitano Keiji Hanada Masayuki Furukawa Ken Kawabe Yoshiyuki Majima Toru Shimosegawa Division of Endoscopy Shizuoka Cancer Center Clinic of Genetic Medicine Shizuoka Cancer Center Department of Surgery Kyoto University Graduate School of Medicine Division of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Center for Gastroenterology Teine-Keijinkai Hospital Department of Surgery Tohoku University Graduate School of Medicine Department of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital East Department of Surgery Teikyo University School of Medicine Division of Cancer Genomics National Cancer Center Research Institute Institute for Integrated Medical Sciences Tokyo Women’s Medical University Department of Internal Medicine Kyorin University School of Medicine Division of Gastroenterology Yokohama City University Graduate School of Medicine Division of Hepatobiliary and Pancreatic Medical Oncology Kanagawa Cancer Center Department of Gastroenterology Aichi Cancer Center Hospital Department of Gastroenterology Kanazawa University Graduate School of Medicine Department of Surgery Japan Bapist Hospital Department of Gastroenterology and Hepatology Kyoto University Graduate School of Medicine Clinical Genetics Unit Kyoto University Graduate School of Medicine Center for Genomic Medicine Kyoto University Graduate School of Medicine Osaka Medical Center for Cancer and Cardiovascular Diseases Second Department of Internal Medicine Wakayama Medical University Department of Gastroenterology Onomichi General Hospital Department of Gastroenterology NationalKyushu Cancer Center Department of Medicine and Bioregulatory Sciences Kyushu University Graduate School of Medical Science Pancreatic Cancer Action Network Department of Gastroenterology Tohoku University Graduate School of Medicine

Familial pancreatic cancer (FPC) is broadly defined as two first-degree-relatives with pancreatic cancer (PC) and accounts for 4%-10% of PC. Several genetic syndromes, including Peutz-Jeghers syndrome, hereditary pancreatitis, hereditary breast-ovarian cancer syndrome(HBOC), Lynch syndrome, and familial adenomatous polyposis (FAP), also have increased risks of PC, but the narrowest definition of FPC excludes these known syndromes. When compared with other familial tumors, proven genetic alterations are limited to a small proportion (Caucasian) and a younger onset are common also in FPC. In European countries, "anticipation" is reported in FPC families, as with other hereditary syndromes; a trend toward younger age and worse prognosis is recognized in the late years. The resected pancreases of FPC kindred often show multiple pancreatic intraepithelial neoplasia (Pan IN) foci, with various K-ras mutations, similar to colorectal polyposis seen in the FAP patients. As with HBOC patients, a patient who is a BRCA mutation carrier with unresectable pancreatic cancer (accounting for 0%-19% of FPC patients) demonstrated better outcome following platinum and Poly (ADP-ribose) polymerase inhibitor treatment. Western countries have established FPC registries since the 1990 s and several surveillance projects for highrisk individuals are now ongoing to detect early PCs. Improvement in lifestyle habits, including non-smoking, is recommended for individuals at risk. In Japan, the FPC study group was initiated in 2013 and the Japanese FPC registry was established in 2014 by the Japan Pancreas Society.

关键词： familial pancreatic cancer registry high risk genetic surveillance

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Diagnosis of subepithelial tumors in the upper gastrointestinal tract by endoscopic ultrasonography

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World Journal of Radiology 2010年第8期2卷 289-297页

作者： Hiroki Sakamoto Masayuki kitano Masatoshi Kudo Division of Gastroenterology and Hepatology Department of Internal MedicineKinki University School of MedicineOsaka-Sayama 589-8511Japan

Endoscopic ultrasonography(EUS) is the most accurate procedure for detecting and diagnosing subepithelial tumors,due to its higher sensitivity and specificity than other imaging *** can characterize lesions by providing information on echogenic origin,size,borders,homogeneity,and the presence of echogenic or anechoic *** echoendoscopes,and recently also electronic radial echoendoscopes,can be used with color Doppler or power Doppler to assess the vascular signals from subepithelial masses,and thus permit the differentiation of vascular structures from cysts,as well as the assessment of the tumor blood ***,the diagnostic accuracy of EUS imaging alone has been shown to be low in subepithelial lesions with 3rd and 4th *** is also difficult to differentiate exactly between benign and malignant tumors and to gain an accurate picture of histology using *** the other hands,EUS guided fine needle aspiration(EUS-FNA) can provide samples for cytologic or histologic *** lesions of the 3rd and the 4th EUS layers,more than in 1 cm diameter are recommended,and histologic confirmation using endoscopic submucosal resection or EUSFNA should be obtained when ***,EUSFNA plays an important role in the clinical management of subepithelial *** improvements in endoscopic technology are expected to be more useful modalities in differential diagnosis and discrimination between benign and malignant subepithelial

关键词： Endoscopic ultrasonography Submucosal tumor Subepithelial tumor

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评估胃肠道间质瘤的潜在恶性风险:逆向谐波超声造影的价值

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世界核心医学期刊文摘（胃肠病学分册） 2005年第10期1卷 49-50页

作者： Fukuta N. kitano M. Maekawa K. M. Kudo 程欣 Department of Gastroenterology and Hepatology Kinki University School of Medicine 377-2 Ohno-Higashi Osaka-Sayama 589-8511 Japan

Background:Recently, contrast agents for ultrasonography (US) such as Levovist have been introduced for routine clinical use. The contrast-enhanced US with Levovist permits evaluation of the intratumoral vascularity of hepatic and pancreatic tumors and is useful for their differential diagnosis. The purpose of the present study was to assess tumor vessels and the parenchymal flow of gastrointestinal stromal tumors (GISTs) by contrast-enhanced coded pha-se-inversion harmonic US and to evaluate whether vascularity is related to the malignant grade of the GISTs. Methods:Thirteen patients with GISTs were included in the present study. Tumors were observed in a real-time fashion of contrast-enhanced coded phase-inversion harmonic US after the injection of Levovist (400 mg/ml). The vascular patterns were compared with tumor size, histological diagnosis, KIT mutations, and clinical findings such as metastasis. Results:The contrast-enhanced US images of the GISTs were classified into two types according to the blood flow area of the tumors as seen by real-time continuous imaging of the tumor vessels. The image pattern “Poor" represented vessels flowing only in the peripheral part of the tumor, and “Rich" represented abundant vessels flowing from the periphery to the central part of the tumor. According to the contrast-enhanced US images, five GISTs were classified as “Poor" and the others as “Rich." Based on the final diagnosis, all tumors with “Poor" images were determined to be benign GISTs, and the rest tumors except one with “Rich" images were determined to be malignant GISTs. Conclusions:Contrast-enhanced US image is more closely correlated with the final diagnosis than the histological findings.

关键词：胃肠道间质瘤超声造影血供胰腺肿瘤超声成像技术鉴别诊断恶性程度血流供应血管数量体实

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