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Imported cases of dengue fever in Russia during 2010-2013

Asian Pacific Journal of Tropical Medicine 2015年第2期8卷 90-93页

作者： Sergeeva EI ternovoi va.cha.sov ev Berillo SA Demina OK Shikov AN Plasunova IV Kartashov M Ju Agafonov AP State Research Center of Virology and Biotechnology "Vector" KoltsovoNovosibirsk Region630559Russia

Objective:To confirm dengue infection among Russian tourists returned from Southeast and Mexico in 2010-2013 with clinical signs of ***:Blood and serum samples from patients were *** antigen and human IgM/IgG antibodies to dengue virus were identified using commercial tests manufactured by "Standard Diagnostics,INC.",*** test was used for the quantitative analyses of human IgM/IgG antibodies to dengue virus( "Orgenics Ltd.",Israel).Viral RNA was delected using commercial real-lime PCR lesls manufactured by "Genome Diagnostics ***.",India and "Vector",*** of revealed dengue viruses were determined employing nucleotide sequencing and phylogenetic analysis of 5'-UTR of the viral ***:A total of 98 collected blood samples were *** samples were positive for at least one of four markers of dengue *** to dengue virus were revealed in 38 samples,in 25 samples IgM were combined with *** antigen was detected in43 samples.22 serum samples were positive for dengue virus *** majority of samples(12patients) from tourists returned from Thailand were positive for genotype 1 of dengue virus,2nd and 4lh genotype were identified each in 1 ***:Due to laboratory confirmed cases of imported dengue fever in Russia,the differential diagnosis of dengue is strictly recommended for tourists returning from endemic areas.

关键词： Southeast Asia Tourists Dengue fever Diagnosis

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