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Zika virus spre.ding in South Ame.ica: e.olutionary analysis of e.e.ging ne.tralizing re.istant Phe.79Se. strains

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Asian Pacific Journal of Tropical Me.icine 2016年第5期9卷 432-438页

作者： Marta Giovane.ti teresa Milano Luiz Carlos Alcantara Laura Carcangiu e.e.nora Ce.la Ale.sia Lai Ale.sandra Lo Pre.ti Ste.ano Pascare.la Gianguglie.mo Ze.e.de. Silvia Ange.e.ti Massimo Ciccozzi De.artme.t of Infe.tious Parasitic and Immunome.iate. Dise.se. National Institute of HealthRomeItaly De.artme.t of Biology University of Rome ‘Tor Vergata’RomeItaly Laboratory of He.atology Genetic and Computational Biology Goncalo Moniz Research Center Oswaldo Cruz Foundation (LHGB/CPq GM/FIOCRUZ)SalvadorBahiaBrazil Dipartime.to di Scie.ze.Biochimiche.‘A. Rossi Fane.li’ Universita La Sapienza00185 RomeItaly De.artme.t of Public He.lth and Infe.tious Dise.se. Sapienza University of RomeRomeItaly Laboratory of Infe.tious Dise.se. and Tropical Me.icine University of Milan Clinical Pathology and Microbiology Laboratory University Hospital Campus Bio-Medico of RomeRomeItaly Unive.sity Campus Bio-Me.ico RomeItaly

Obje.tive. To inve.tigate.the.ge.e.ic dive.sity of Zika virus(ZIKV) and the.re.ationships e.isting among the.e.circulating viruse. worldwide. To e.aluate.the.ge.e.ic polymorphisms harboure. from ZIKV that can have.an influe.ce.on the.virus circulation. Me.hods: Thre. diffe.e.t ZIKV datase. we.e.built. The.first datase. include. 63 e.ge.e.se.ue.ce., the.se.ond one.22 NS3 se.ue.ce. and the.third datase. was compose. of 108 NS5 ge.e.se.ue.ce.. Phyloge.e.ic and se.e.tive.pre.sure.analysis was pe.forme.. The.e.ite. nucle.c acid alignme.t from the.e.ve.ope.datase. was use. to ge.e.ate.a conce.tual translation to the.corre.ponding pe.tide.se.ue.ce. through UGe.e.software. Re.ults: The.phyloge.graphic re.onstruction was able.to discriminate.unambiguously that the.Brazilian strains are.be.onge. to the.Asian line.ge. The.structural analysis re.e.ls inste.d the.pre.e.ce.of the.Se. re.idue.in the.Brazilian se.ue.ce.(howe.e. alre.dy obse.ve. in othe. pre.iously re.orte. ZIKV infe.tions) that could sugge.t the.pre.e.ce.of a ne.tralization-re.istant population of viruse.. Conclusions: Phyloge.e.ic, e.olutionary and se.e.tive.pre.sure.analysis contribute. to improve.the.knowle.ge.on the.circulation of ZIKV.

关键词： Zika virus Phyloge.y e.olution

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空气的海洋

空气的海洋

Cyclic e. and P4 on Alzhe.me.’s Dise.se.Pathways

1982年

作者：（美）施奈德（snyder e.e.）曹承康译注

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Advance. in Alzhe.me.'s Dise.se 2017年第1期6卷 32-44页

作者： teresa S. Wile. Jason T. Haraldse. Wile. Compounding Syste.s Santa Fe New Mexico USA De.artme.t of Physics University of North Florida Florida USA

In re.e.t ye.rs, Alzhe.me.’s dise.se.has be.n cle.rly linke. to the.de.radation of microtubule. and microtubule.associate. tau (τ) and β-amyloid (βA) prote.ns. Through an e.amination and e.aluation of curre.t lite.ature. we.asse.s the.possible.e.fe.ts of the.ste.oid hormone. on τ hype.phosphorylation and the.re.ulation of βA prote.ns and the.r influe.ce.on Alzhe.me.’s de.e.tia and me.ory loss. We.pre.e.t a me.hanism by which Alzhe.me.’s case. may be.re.uce. or pe.haps e.e. pre.e.te. through the.use.of non-synthe.ic, ste.oid hormone. pre.cribe. in a cyclic dosing sche.ule.that mimics the.rhythmic, e.calating and de.ce.ding production normally obse.ve. in a re.roductive.fe.ale.body. Give. the.ability of e.troge. to pre.e.t τ hype.phosphorylation and incre.se.me.abolism of the.βA pre.ursor prote.n, we.propose.the.possibility of controlling both prote.n cycle. through the.e.oge.ous application of e.troge. and proge.te.one.may he.p those.patie.ts with active.dise.se.as we.l as pre.e.t the.onse. of Alzhe.me.’s and othe. ne.rode.e.e.ative.dise.se..

关键词： Hormone. e.tradiol Proge.te.one Bio-Me.tic Tre.tme.t

Asse.sme.t of microbial pools by an innovative.microbiological te.hnique.during the.co-composting of olive.mill by-products

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Agricultural Scie.ce. 2011年第2期2卷 104-110页

作者： teresa Casacchia Pie.ro Toscano Adriano Sofo e.zo Pe.ri CRA Centro di Ricerca per l"Olivicoltura e l"Industria Olearia Dipartime.to di Scie.ze.de. Siste.i Colturali Forestali e dell’Ambiente Università degli Studi della Basilicata

Diffe.e.t mixture. of olive.pomace.(OP), olive.mill waste.ate. (OMWW) and olive.pruning re.idue. (OPR) we.e.ae.obically co-composte. unde. natural conditions. Compost te.pe.ature.showe. a sharp incre.se.in the.first 40-60 days, followe. by a stabilization at 60°C and a de.line.afte. 150 days, whe.e.s compost wate. conte.t range. from 50-55% to 25-30%. Total and se.e.-tive.microbial counts we.e.followe. throughout the.e.pe.ime.t by me.ns of innovative.(IMT) and conve.tional (CMT) microbiological te.hnique.. Pse.domonas spp., anae.obic bacte.ia, actino-myce.e., and fungi re.che. le.e.s of 8, 7, 5 and 6 log CFU g–1 compost, re.pe.tive.y, with a slight de.re.sion afte. 30-80 days. Total and fe.al coliforms strongly de.re.se. during the.com-posting proce.s. The.use.of IMT allowe. to de.te.t a highe. and more.stable.growth of micro-organisms if compare. to CMT. IMT was de.-onstrate. to be.an appropriate.and re.iable.me.hod for monitoring the.microbial pools dur-ing the.co-composting proce.s.

关键词： Composting Olive Mill Waste.ate. Olive Pomace Pruning Re.idue.

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钻井技术新进展

石油勘探与开发 2003年第1期30卷 78-78页

作者： Robe. e.snyder 谢力单位不详

哈里伯顿公司开发的HYDRO-GUARD是一种抑制性水基钻井液。2002年初进行的现场试验表明，这种钻井液在深水和大陆架作业很宽的温度范围内，具有稳定的屈服点和凝胶强度，可以抑制泥岩水化，在钻速度较高时提高泥岩段井眼的井壁稳定性。... 详细信息

哈里伯顿公司开发的HYDRO-GUARD是一种抑制性水基钻井液。2002年初进行的现场试验表明，这种钻井液在深水和大陆架作业很宽的温度范围内，具有稳定的屈服点和凝胶强度，可以抑制泥岩水化，在钻速度较高时提高泥岩段井眼的井壁稳定性。钻头处能够控制流便特性的聚合物的剪切稀释作用既利于更快地钻进，也保证了能有效地收集呼口号去除钻屑。将泥岩水化作用减至最小的专利聚合物添加剂有两种：一种是在低浓度下有效的强凝聚剂，可包裹钻屑；另一种防止富泥岩的地层水化和削蚀

关键词：石油钻井技术进展抑制性水基钻井液泡沫钻井液智能钻杆

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能与原子能

能与原子能

Me.icinal plants and natural products as ne.roprote.tive.age.ts in age.re.ate. macular de.e.e.ation

1983年

作者：（美）斯奈德（snyder e.e.原译施奈德）王镁译注

本书包括两个部分。第一部分就人类对能源的利用作了历史性的回顾和展望。第二部分介绍放射性的发现和本世纪对放射性同位素的研究和应用、核裂变和核聚变过程以及对核反应堆的控制等。每节原文后有语法注释和译文，书末附有术语注释及... 详细信息

ISBN: (纸本)9215·203

本书包括两个部分。第一部分就人类对能源的利用作了历史性的回顾和展望。第二部分介绍放射性的发现和本世纪对放射性同位素的研究和应用、核裂变和核聚变过程以及对核反应堆的控制等。每节原文后有语法注释和译文，书末附有术语注释及词汇表。

关键词：对照读物英语英、中核能能

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Ne.ral Re.e.e.ation Re.e.rch 2020年第12期15卷 2207-2216页

作者： Francisco Bosch-More.l Victoria Villagrasa teresa Orte.a Nuria Ace.o Dolore. Muñoz-Mingarro Me.ge.ia Gonzále.-Rose.de.e.carna Castillo MAmparo Sanahuja Pilar Soriano Isabe. Martíne.-Solís Biome.ical Scie.ce. Institute Universidad Cardenal Herrera-CEUCEU UniversitiesAlfara del PatriarcaValenciaSpain De.artme.t of Biome.ical Scie.ce. Faculty of Health SciencesUniversidad Cardenal Herrera-CEUCEU UniversitiesAlfara del PatriarcaValenciaSpain De.artme.t of Pharmacy Faculty of Health SciencesUniversidad Cardenal Herrera-CEUCEU UniversitiesAlfara del PatriarcaValenciaSpain De.artme.t of Pharmacology Pharmacognosy and BotanyUniversidad Complutense de MadridMadridSpain De.artme.t of Pharmace.tical and He.lth Scie.ce. Faculty of PharmacyUniversidad San Pablo-CEUCEU UniversitiesMadridSpain De.artme.t of Che.istry and Bioche.istry Faculty of PharmacyUniversidad San Pablo-CEUCEU UniversitiesMadridSpain ICBiBe.Botanical Garde. University of ValenciaValenciaSpain

The.re.ina may suffe. ne.rode.e.e.ative.damage.,as othe. tissue. of the.ce.tral ne.vous syste. do,and se.ious e.e.dise.se. may *** of the. is age.re.ate. macular de.e.e.ation,which cause. progre.sive.loss of vision due.to re.ina *** of age.re.ate. macular de.e.e.ation focuse. on antioxidant age.ts and anti-vascular e.dothe.ial growth factor compounds,among othe.s,that pre.e.t/diminish oxidative.stre.s and re.uce.ne.vascularisation *** phytoche.icals,me.icinal plants and/or plant-die. supple.e.ts might be.a use.ul adjunct in pre.e.tion or tre.tme.t of age.re.ate. macular de.e.e.ation owing to the.r antioxidant and anti-vascular e.dothe.ial growth factor *** re.ie. article.pre.e.ts the.most inve.tigate. plants and natural products in re.ation to age.re.ate. macular de.e.e.ation,such as saffron,ginkgo,bilbe.ry and blue.e.ry,curcuma or turme.ic,carote.oids,polyphe.ols,and vitamins C and *** study provide. up-to-date.information on the.e.fe.ts,tre.tme.ts,safe.y and e.ficie.cy of the.e.phytothe.apy products.

关键词： age.re.ate. macular de.e.e.ation bilbe.ry blue.e.ry curcuma carote.oids ginkgo polyphe.ols saffron vitamins

Non-ce.iac glute. se.sitivity:Time.for sifting the.grain

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世界胃肠病学杂志：英文版 2015年第27期21卷 8221-8226页

作者： Luca e.li Le.a Roncoroni Maria teresa Barde.la Ce.te. for Pre.e.tion and Diagnosis of Ce.iac Dise.se Gastroenterology and Endoscopy Unit Department of Pathophysiology and Transplantation Università degli Studi di Milano. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico

In the.last fe. ye.rs, a ne. nome.clature.has be.n propose. for the.dise.se.induce. by the.inge.tion of glute., a prote.n pre.e.t in whe.t, rice. barle. and oats. Be.ide. ce.iac dise.se.and whe.t alle.gy, the.most studie. forms of glute.-re.ate. disorde.s characte.ize. by an e.ide.t immune.me.hanism(autoimmune.in ce.iac dise.se.and Ig e.me.iate. in whe.t alle.gy), a ne. e.tity has be.n include., appare.tly not drive. by an abe.rant immune.re.ponse. the.non-ce.iac glute. se.sitivity(NCGS). NCGS is characte.ize. by a he.e.oge.e.us clinical picture.with inte.tinal and e.trainte.tinal symptoms arising afte. glute. inge.tion and rapidly improving afte. its withdrawal from the.die.. The.pathoge.e.is of NCGS is large.y unknown, but a mixture.of factors such as the.stimulation of the.innate.immune.syste., the.dire.t cytotoxic e.fe.ts of glute., and probably the.syne.gy with othe. whe.t mole.ule., are.clue. for the.complicate. puzzle. In addition, the.diagnostic proce.ure. still re.ain proble.atic due.to the.abse.ce.of e.ficie.t diagnostic marke.s; thus, diagnosis is base. upon the.symptomatic re.ponse.to a glute.-fre. die. and the.re.urre.ce.of symptoms afte. glute. re.ntroduction with the.possibility of an important involve.e.t of a place.o e.fe.t. The.te.porary withdrawal of glute. se.ms a re.sonable.the.apy, but the.timing of glute. re.ntroduction and the.corre.t patie.t manage.e.t approach are.have.not ye. be.n de.e.mine..

关键词： Ce.iac dise.se Glute. Glute.-re.ate.disorde.s Glute. se.sitivity Non-ce.iac glute. se.sitivity

Pe.formance.and calibration of quark/gluon-je. tagge.s using 140 fb^(-1) of pp collisions at √s=13 Te. with the.ATLAS de.e.tor

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Chine.e.Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abe.ing N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abre. Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Adde.alli M.J. Addison J. Ade.man A. Adiguze. T. Adye.A.A. Affolde. Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Aghe.rghie.e. A. Ahmad F. Ahmadov W.S. Ahme. S. Ahuja X. Ai G. Aie.li A. Aikot M. Ait Tamlihat B. Aitbe.chikh I. Aize.be.g M. Akbiyik T.P.A. Åke.son A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Albe.ghi J. Albe.t P. Albicocco G.L. Albouy S. Alde.we.re.dt M. Ale.sa I.N. Ale.sandrov C. Ale.a T. Ale.opoulos F. Alfonsi M. Algre. M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Alie. G. Alimonti W. Alkakhi C. Allaire.B.M.M. Allbrooke.J.F. Alle. C.A. Alle.de. Flore. P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvare. e.te.e. A. Alvare. Fe.nande. M. Alve. Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Amble. C. Ame.ung M. Ame.l C.G. Ame. D. Amide. S.P. Amor Dos Santos K.R. Amos V. Ananie. C. Anastopoulos T. Ande.n J.K. Ande.s S.Y. Andre.n A. Andre.zza S. Ange.idakis A. Ange.ami A.V. Anise.kov A. Annovi C. Ante. M.T. Anthony e. Antipov M. Antone.li F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo L. Ape.io Be.la C. Appe.t A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcange.e.ti A.T.H. Arce.e. Are.a J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnae. H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augste. S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azue.os D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Bade. P. Bagnaia M. Bahmani A.J. Baile. V.R. Baile. J.T. Baine. L. Baine. O.K. Bake. e. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian e.M. Baldin P. Bale. e. Ballabe.e.F. Balli L.M. Balte. W.K. Balunas J. Balz e. Banas M. Bandie.amonte.A. Bandyopadhyay S. Bansal L. Barak M. Barakat e.L. Barbe.io D. Barbe.is M. Barbe.o M.Z. Bare. K.N. Bare.ds T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The.ATLAS Collaboration

The.ide.tification of je.s originating from quarks and gluons,ofte. re.e.re. to as quark/gluon tagging,plays an important role.in various analyse. pe.forme. at the.Large.Hadron Collide.,as Standard Mode. me.sure.e.ts and se.rche. for ne. particle. de.aying to quarks ofte. re.y on suppre.sing a large.gluon-induce. *** pape. de.cribe. the.me.sure.e.t of the.e.ficie.cie. of quark/gluon tagge.s de.e.ope. within the.ATLAS Collaboration,using √s=13 Te. proton–proton collision data with an inte.rate. luminosity of 140 fb^(-1) colle.te. by the.ATLAS *** tagge.s with high pe.formance. in re.e.ting je.s from gluon ove. je.s from quarks are.studie.:one.tagge. is base. on re.uire.e.ts on the.numbe. of inne.-de.e.tor tracks associate. with the.je.,and the.othe. combine. se.e.al je. substructure.obse.vable. using a booste. de.ision tre..A me.hod is e.tablishe. to de.e.mine.the.quark/gluon fraction in data,by using quark/gluon-e.riche. subsample. de.ine. by the.je. *** in tagging e.ficie.cy be.we.n data and simulation are.provide. for je.s with transve.se.mome.tum be.we.n 500 Ge. and 2 Te. and for multiple.tagge. working points.

关键词： ATLAS Je. QUARK GLUON TAGGING