检索结果-南通市图书馆

Hepatitis B vaccine by intradermal route in non responder patients:An update

World Journal of Gastroenterology 2014年第30期20卷 10383-10394页

作者： Martina Filippelli Elena Lionetti Alessia Gennaro Angela Lanzafame teresa arrigo Carmelo Salpietro Mario La Rosa Salvatore Leonardi Department of Medical and Pediatric Science University of Catania95100 CataniaItaly Department of Pediatric Sciences University of Messina98100 MessinaItaly

Vaccination is the main prophylactic measure to reduce the mortality caused by hepatitis B virus (HBV) infection in healthy subjects since the immune response to hepatitis B recombinant vaccination occurs in over 90% of general population. Individuals who develop an anti-HBs titer less than 10 mIU/mL after primary vaccination cycle are defined “no responders”. Many factors could cause a non response to the HBV vaccination, such as administration of the vaccine in buttocks, impaired vaccine storage conditions, drug abuse, smoking, infections and obesity. Moreover there are some diseases, like chronic kidney disease, human immunodeficiency virus infection, chronic liver disease, celiac disease, thalassaemia, type I diabetes mellitus, down’s syndrome and other forms of mental retardation that are characterized by a poorer response to HBV vaccination than healthy subjects. To date it is still unclear how to treat this group of patients at high risk of hepatitis B infection. Recent studies seem to indicate that the administration of HBV recombinant vaccine by the intradermal route is very effective and could represent a more useful strategy than intramuscular route. This review focuses on the use of anti hepatitis B vaccine by intradermal route as alternative to conventional intramuscular vaccine in all non responder patients. A comprehensive review of the literature using PubMed database, with appropriate terms, was undertaken for articles in English published since 1983. The literature search was undertaken in September 2013.

关键词： Hepatitis B virus Vaccine Intradermal route Non responders Update

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Role of the diet as a link between oxidative stress and liver diseases

引用

World Journal of Gastroenterology 2015年第2期21卷 384-395页

作者： teresa arrigo Salvatore Leonardi Caterina Cuppari Sara Manti Angela Lanzafame Gabriella D'Angelo Eloisa Gitto Lucia Marseglia Carmelo Salpietro Department of Pediatric GynecologicalMicrobiological and Biomedical SciencesUniversity of Messina98122 MessinaItaly Department of Medical and Pediatrics Science University of Catania95123 CataniaSicilyItaly

Oxidative stress is caused by an imbalance between the production of reactive oxygen(free radicals) and the body's ability(antioxidant capacity) to readily detoxify the reactive intermediates or easily repair the resulting damage. An adequate diet, characterized by daily intake of foods associated with improvementsin the total antioxidant capacity of individuals and reduced incidence of diseases related to oxidation, can modulate the degree of oxidative stress. In fact, dietderived micronutrients may be direct antioxidants, or are components of antioxidant enzymes, leading to improvement of some indicators of hepatic function. However, although their increased dietary intake might be beneficial, literature data are still controversial. This review summarizes what is known about the effects of diet nutrients on oxidative stress, inflammation and liver function. Moreover, we have analyzed:(1) the main nutritional components involved in the production and/or removal of free radicals; and(2) the role of free radicals in the pathogenesis of several hepatic diseases and related comorbidities.

关键词： Nutrition Micronutrients Macronutrients Liver dise

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：