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Hepatobiliary & Pancreatic Diseases International 2013年第6期12卷 656-660页

作者： Xin Chen Hai-Bing Zhang Zhong-Qi Li Xiong-Fei Yu Mei-Fang Yang Hao-Hao Wang Li-song teng Department of Oncology First Affiliated Hospital Zhejiang University School of Medicine State Key Laboratory for Diagnosis and Treatment of Infectious Diseases First Affiliated Hospital Zhejiang University School of Medicine

Transarterial chemoembolization(TACE)may ravage normal liver tissues apart from the neoplastic nodules which offset the anti-tumor *** study aimed to evaluate the recovery of liver reserve function(LRF)after TACE by indocyanine green(ICG)clearance test and other routine liver function ***-six newly diagnosed HCC patients who had undergone TACE as the initial treatment from January 2011 to January 2012 were enrolled in this *** effects of age,basic ICG clearance rate and interval time between two assessments on the recovery of LRF were *** found that ICG retention rate at the 15 minutes(ICGR15)was significantly increased after TACE(12.3±8.1%vs 16.8±12.1%,P55 years,20.3±12.5%vs 13.7±7.2%,P<0.01).The interval of ICG test also affected the ICGR15 value(≤47days,17.8±11.4%after vs 12.1±7.1%before TACE,P<0.01).Our data suggested that TACE decreased LRF,especially in older *** test was more sensitive to evaluate the recovery of LRF after TACE than the Child-Pugh grade and routine liver function tests.

关键词： hepatocellular carcinoma transarterial chemoembolization liver reserve function indocyanine green clearance

Estrogen receptor a variant ERa46 mediates growth inhibition and apoptosis of human HT-29 colon adenocarcinoma cells in the presence of 17β-oestradiol

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Chinese Medical Journal 2008年第11期121卷 1025-1031页

作者： JIANG Hai-ping teng Rong-yue WANG Qi ZHANG Xing WANG Hao-hao CAO Jiang teng Li-song Department of Oncological Surgery First Affiliated HospitalZhejiang University School of Medicine Hangzhou Zhejiang 310003 China Sir Run Run Shaw Institute of Clinical Medicine Zhejiang University Key Laboratory of Biotherapy of Zhejiang Province Hangzhou Zhejiang 310016 China

Background Estrogen is involved in suppression of colon cancer development and exerts its function via estrogen receptors α and β （ERa, ERβ）. The recently identified ERα46 resulted from exon 1-deletion from the 66-kDa full length form of ERa66 is devoid of the transactivation domain AF-1, whose function remains largely unknown. Methods In this study, we compared the expression of ERa46 mRNA in 32 normal colorectal tissues and their matched colorectal cancer tissues by real-time quantitative polymerase chain reaction （PCR）. Human colon adenocarcinoma cell HT-29, that has low endogenous expression of ERα46, was transfected with ERα46-expression vector; methyl thiazolyl tetrazolium （MTT） assay, flow cytometry, DNA fragmentation and TUNEL staining were used to evaluate the proliferation and apoptosis status of the cells in the presence of 17β-oestradiol. Results Higher ERα46 mRNA levels were observed in normal colorectal tissues than in the corresponding cancer tissues. ERα46-transfected cells showed a significantly decreased growth rate than control cells and an accumulation of cells in the G0/1 phase and a reduced proportion of cells in G2/M phase after exposed to 10^-8 mol/L 17β-oestradiol. There were also more positive TUNEL stained cells in ERα46-transfected cells than the control cells in the presence of 17β-oestradiol （P 〈0.05）. Conclusions These data suggest that ERα46 may be involved in the development and/or progression of colorectal cancer via mediating growth inhibition and apoptosis of cancer cells in the presence of 17β-oestradiol.

关键词： estrogen receptors α46 17β-oestradiol colorectal cancer proliferation apoptosis

Anti-colorectal cancer effects of tripolinolate A from Tripolium vulgare

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Chinese Journal of Natural Medicines 2017年第8期15卷 576-583页

作者： CHEN Lu WANG Wen-Ling song teng-Fei XIE Xin YE Xue-Wei LIANG Ying HUANG Hao-Cai YAN Shi-Lun LIAN Xiao-Yuan ZHANG Zhi-Zhen Ocean College Zhoushan CampusZhejiang UniversityZhoushan 316021China College of Pharmaceutical Sciences Zhejiang UniversityHangzhou 310058China

Tripolinolate A(TLA) is recently identified as a new compound from a halophyte plant Tripolium vulgare and has been shown to have significant in vitro activity against the proliferation of colorectal cancer and glioma cells. This study was designed to further investigate the effects of TLA on the proliferation of human normal cells, and the apoptosis and cell cycle in colorectal cancer cells, and the growth of tumors in the colorectal cancer-bearing animals. The data obtained from this study demonstrated that: 1) TLA had much less cytotoxicity in the human normal cells than the colorectal cancer cells; 2) TLA remarkably induced apoptosis in the human colorectal cancer cells and blocked cell cycle at G2/M phase, and 3) TLA had significant anti-colorectal cancer activity in the tumor-bearing animals.

关键词： Tripolinolate A Colorectal cancer cells Apoptosis Cell cycle Anti-colorectal tumor effects

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滕松茂穴位注射临床经验

针灸临床杂志 2008年第6期24卷 37-38页

作者：李建萍滕松茂上海市徐汇区中心医院上海200031 上海市华东医院上海200040

滕松茂老师从事临床工作40余年,熟岐黄之术,享国务院政府特殊津贴,临床中善于运用穴位注射的方法治疗疾病,笔者有幸成为上海市针推著名老中医继承班学员,亲聆教诲,得到颇多启示,受益非浅.

关键词：穴位注射名医经验滕松茂

Tectonic evolution of the Huangling dome and its control effect on shale gas preservation in the north margin of the Yangtze Block, South China

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China Geology 2020年第1期3卷 28-37页

作者： Jun-feng Zhang Gang-yi Zhai Da-ming Wang Shu-jing Bao Ke Chen Hao-han Li teng song Peng Wang Zhi Zhou Oil and Gas Survey China Geology SurveyMinistry of Natural ResourcesBeijing 100083China

Significant breakthroughs of shale gas exploration have been made in Lower Cambrian and Sinian shale in the north margin of the Yangtze Block,South *** drill wells with industrial gas flow located in the southern margin of the Huangling *** on the geological survey,2D seismic,geochronological and drill wells data,the tectonic evolution history of Huangling dome was studied,and its control effect on the preservation condition of shale gas was *** result shows that the Huangling dome might undergo four tectonic stages:(1)About 800 Ma,granite intrusion in the Huangling dome basement,primarily of granites replaced metamorphism rocks;(2)800-200 Ma,no significant tectonic movement with slowly buried history;(3)From 200 Ma,multi-phase uplift and the sedimentary rocks was eroded in the core of the Huangling *** gas in the Cambrian and Sinian strata was well preserved in the margin of the Huangling dome as the following reasons:(1)The Sinian shale was buried about 7.8 km indepth during Middle Jurassic,source rocks have a suitable thermal maturity for shale gas;(2)The rigid basement of the Huangling dome was mainly composed by homogeneity granite,without intensive *** the main challenges of the widely distributed Lower Cambrian and Sinian shale are highmaturity and intensive deformation,a geological unit with a dome probably is a favorable zone for the old age shale ***,it indicates that the adjacent zone of the Xuefengshan,Shennongjia and Hannan are the geological units with a dome and probably have potentials for the exploration of shale in the Lower Cambrian and Sinian.

关键词： Shale gas Degree of thermal evolution Huangling dome Tectonic evolution Preservation conditions Lower Cambrian and Sinian South China

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试论制度的评价标准

烟台大学学报（哲学社会科学版） 2011年第4期24卷 13-17页

作者：滕松梅烟台大学人文学院山东烟台264005

由于社会生产力高度发展和全球化交往的日益广泛,当代中国的国情发生巨大变化,例如生产资料所有制形式多样化、社会组织结构庞杂、人际关系复杂、各种思想文化流派并存等等。制度在社会中的作用越来越重要,对制度评价标准的研究可以进... 详细信息

由于社会生产力高度发展和全球化交往的日益广泛,当代中国的国情发生巨大变化,例如生产资料所有制形式多样化、社会组织结构庞杂、人际关系复杂、各种思想文化流派并存等等。制度在社会中的作用越来越重要,对制度评价标准的研究可以进一步加强我们对制度本身以及制度建设的认识。

关键词：制度标准人文价值效率现实性自洽性实践

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阿富汗塔利班宣传战探析

河南师范大学学报（哲学社会科学版） 2014年第5期41卷 119-122页

作者：滕松艳闽南师范大学马克思主义学院福建漳州363000

宣传战是现代战争的重要组成部分。阿富汗战争开始后,基于阿富汗经济发展水平较低的现实,通过广播电台、录音带、手机等媒介发布信息成为塔利班宣传的主渠道。随着现代通信媒介的不断发展,塔利班开始使用推特、脸谱等社交网站发布信息,... 详细信息

宣传战是现代战争的重要组成部分。阿富汗战争开始后,基于阿富汗经济发展水平较低的现实,通过广播电台、录音带、手机等媒介发布信息成为塔利班宣传的主渠道。随着现代通信媒介的不断发展,塔利班开始使用推特、脸谱等社交网站发布信息,也善于利用西方媒体传播它的思想和主张。塔利班的宣传战削弱了美国发动阿富汗战争的道义优势,增加了驻阿美军在阿富汗行动的困难,延缓了阿富汗国家重建的进程。美国及其盟友对塔利班宣传战的反制表明,在现代社会,借力网络技术驾驭和操纵更多的信息资源和社会影响力,日益成为国际政治权力博弈的重要手段。

关键词：塔利班阿富汗宣传战

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《德意志意识形态》中蕴涵的交往思想

烟台大学学报（哲学社会科学版） 2009年第2期22卷 9-13页

作者：滕松梅烟台大学人文学院山东烟台264005

长期以来,我们对于交往的研究大多停留于社会学层面。重新阅读马克思、恩格斯的《德意志意识形态》,从哲学的角度对马克思、恩格斯的交往思想加以解读,可以深入揭示交往的内涵和外延、交往的总体性和多样性以及交往在社会发展中的巨大... 详细信息

长期以来,我们对于交往的研究大多停留于社会学层面。重新阅读马克思、恩格斯的《德意志意识形态》,从哲学的角度对马克思、恩格斯的交往思想加以解读,可以深入揭示交往的内涵和外延、交往的总体性和多样性以及交往在社会发展中的巨大作用。

关键词：交往生产关系生产力分工生产(劳动)

基于复合储能系统的矿区电网频率弹性提升方法

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电网技术 2019年第7期43卷 2291-2298页

作者：钟睿滕松梁睿沈兴来中国矿业大学电气与动力工程学院江苏省徐州市221116 江苏省煤矿电气与自动化工程实验室(中国矿业大学) 江苏省徐州市221116 国网徐州供电公司江苏省徐州市221116

为构建高比例可再生能源供电的弹性矿区电网,提出了一种由废弃矿井抽水蓄能与超级电容构成的复合储能提升矿区电网频率弹性的方法。基于弹性电网框架,考虑弹性力与调频特性的重合与区别,进而针对性地提出5种弹性指标。在计及超级电容荷... 详细信息

为构建高比例可再生能源供电的弹性矿区电网,提出了一种由废弃矿井抽水蓄能与超级电容构成的复合储能提升矿区电网频率弹性的方法。基于弹性电网框架,考虑弹性力与调频特性的重合与区别,进而针对性地提出5种弹性指标。在计及超级电容荷电状态的基础上,充分发挥抽蓄机组与超级电容各自的技术优势,使储能系统兼具能量密度高和功率密度高的特点,从系统适应能力、恢复能力及惯性能力角度提高系统频率弹性。通过此种方法,构建了能够适应负荷阶跃变化以及连续调节任务的频率闭环控制结构,在大功率设备集中启动或井下小功率设备频繁启停时有效稳定频率水平,提升矿区电网供电可靠性。最后,在MATLAB/Simulink仿真环境中搭建系统模型,通过仿真验证了文中方法的有效性。

关键词：弹性电网复合储能频率调节矿区电网

基于最小位移的磁悬浮转子变极性LMS反馈不平衡补偿

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振动与冲击 2015年第7期34卷 24-32页

作者：宋腾韩邦成郑世强冯锐北京航空航天大学惯性技术重点实验室北京100191 北京航空航天大学新型惯性仪表与导航系统技术国防重点学科实验室北京100191

针对高速电机磁悬浮转子受不平衡扰动时位移精度下降的问题,提出一种基于最小位移原则的变极性最小均方误差(least mean square,LMS)反馈不平衡补偿策略,通过在线辨识位移信号中的转速同频分量,引入反馈补偿来增加系统对同频分量的广义... 详细信息

针对高速电机磁悬浮转子受不平衡扰动时位移精度下降的问题,提出一种基于最小位移原则的变极性最小均方误差(least mean square,LMS)反馈不平衡补偿策略,通过在线辨识位移信号中的转速同频分量,引入反馈补偿来增加系统对同频分量的广义动刚度,实现不平衡补偿。利用广义根轨迹分析了引入补偿后系统的闭环稳定性,同时针对仅以负极性或正极性引入补偿后,闭环系统均存在临界转频以上或以下发散的问题,设计了通过切换引入补偿的极性来穿越临界转频,从而实现引入LMS反馈补偿后全转速范围闭环稳定。实验结果表明,该方法在全转速范围内均能大幅减小位移信号中的转速同频分量。

关键词：主动磁悬浮轴承最小位移不平衡补偿变极性LMS反馈广义根轨迹