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Fasting biochemical hypoglycemia and related-factors in nondiabetic population: Kanagawa Investigation of Total Check-up Data from National Database-8

引用

World Journal of Diabetes 2021年第7期12卷 1131-1140页

作者： Kotone Tanaka Ryoko Higuchi Kaori Mizusawa teiji nakamura Kei Nakajima Graduate School of Health Innovation Kanagawa University of Human ServicesKawasaki 210-0821Japan School of Nutrition and Dietetics Faculty of Health and Social ServicesKanagawa University of Human ServicesYokosuka 238-8522Japan Department of Endocrinology and Diabetes Saitama Medical CenterSaitama Medical UniversityKawagoe 350-8550Japan

BACKGROUND In healthy people,the lowest daily blood glucose concentration is usually observed in the early morning,after overnight ***,the clinical relevance and the prevalence of fasting biochemical hypoglycemia(FBH)are poorly understood in people who do not have diabetes,although the clinical implications of such hypoglycemia have been extensively studied in patients with *** can be influenced by many factors,including age,sex,body mass,smoking,alcohol drinking,exercise levels,medications,and eating behaviors,such as breakfast skipping and late-night *** To determine the prevalence of FBH and investigated its association with potential risk factors in a population without *** Clinical parameters and lifestyle-related factors were assessed in a cross-sectional study of 695613 people aged 40-74 years who had undergone a health check-up(390282 men and 305331 women).FBH was defined as fasting plasma glucose<70 mg/dL(3.9 mmol/L)after overnight fasting,regardless of any *** absence of diabetes was defined as HbA1c<6.5%,fasting plasma glucose<126 mg/dL(7.0 mmol/L),and no pharmacotherapy for *** logistic regression analysis,with adjustment for confounding factors,was used to identify *** FBH was present in 1842 participants(0.26%).There were significantly more women in the FBH group(59.1%)than in the non-FBH group(43.9%).Values of most of the clinical parameters,but not age,were significantly lower in the FBH group than in the non-FBH *** regression analysis showed that a body mass index of≤20.9 kg/m2(reference:21-22.9 kg/m2)and current smoking were significantly associated with FBH,and this was not altered by adjustment for age,sex,and pharmacotherapy for hypertension or *** sex was associated with *** the data were analyzed according to sex,men in their 60s or 70s appeared more likely to experience FBH compared with their 40s,whereas men in their 50s and

关键词： Hypoglycemia Body mass index Age Smoking Women Breakfast skipping

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