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电子器件 2006年第4期29卷 1329-1333页

作者：张富彬 HO Ching-yen 彭思龙中国科学院自动化研究所国家专用集成电路设计工程研究中心 Synopsys Inc.Mountain View CA 94043

讨论了静态时序分析算法及其在IC设计中的应用。首先,文章讨论了静态时序分析中的伪路径问题以及路径敏化算法,分析了影响逻辑门和互连线延时的因素。最后通过一个完整的IC设计流程介绍了静态时序分析的应用。

关键词：静态时序分析敏化路径伪路径 D-算法

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动态串扰噪声识别算法

小型微型计算机系统 2007年第3期28卷 573-576页

作者：张富彬 Ching-yen Ho 彭思龙中国科学院自动化研究所国家专用集成电路设计工程研究中心 Synopsys Inc. Mountain View CA 94043

提出了动态串扰噪声的识别算法.针对基于传统静态时序分析的结果过于保守的缺点,本算法引入了混合时序分析,缩小了时间窗区间,为动态串扰噪声的识别提供了准确的时序信息,与此同时,通过测试生成来验证信号间的逻辑关系,根据这些准确的... 详细信息

提出了动态串扰噪声的识别算法.针对基于传统静态时序分析的结果过于保守的缺点,本算法引入了混合时序分析,缩小了时间窗区间,为动态串扰噪声的识别提供了准确的时序信息,与此同时,通过测试生成来验证信号间的逻辑关系,根据这些准确的时序及逻辑信息,识别出动态串扰噪声.

关键词：动态串扰噪声混合时序分析测试生成

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多组分聚合体系的探索

化学进展 2014年第7期26卷 1099-1106页

作者：王诗琪付长奎危岩陶磊清华大学化学系北京100084

多组分反应是利用三种或者三种以上反应物一锅法得到终产物的反应。在此过程中,无需对中间产物进行分离提纯,而且几乎所有反应物的原子都出现在生成物当中。因此多组分反应经常被用来合成具有复杂结构的化合物。我们在多组分反应中引入... 详细信息

多组分反应是利用三种或者三种以上反应物一锅法得到终产物的反应。在此过程中,无需对中间产物进行分离提纯,而且几乎所有反应物的原子都出现在生成物当中。因此多组分反应经常被用来合成具有复杂结构的化合物。我们在多组分反应中引入可聚合元素,将功能化单体合成和可控聚合结合在一起,一步合成具有特殊官能结构的聚合物。这个体系中的反应均互不干扰,有着良好的匹配效果。因此,得到的产物具有可控的分子量和很窄的分子量分布。与传统方法相比,这种多组分聚合体系节省了反应时间、降低了合成成本、合成途径更加绿色经济。我们现已发展了多种多组分聚合体系,按照复杂程度不同分为二元、三元和四元体系。通过不同的有机小分子反应与可控聚合的结合,我们成功制备了一些通过其他聚合方法难以或是无法合成的新型聚合物,体现了这一聚合方法的特点和优势。随着对多组分聚合体系认识的不断深入,相信我们能够更简便地合成更多结构新颖的聚合物。

关键词：多组分聚合一锅法

结合微孔隙水压力计改良型GR试验系统分析研究(英文)

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岩土工程学报 2004年第6期26卷 832-837页

作者：张达德郦能惠陈柏麟傅新民 Department of Civil Engineering of Chung-Yuan Christian University Chung-Li Taiwan Nanjing Hydraulic Research Institute Nanjing 210029 Jiangsu Department of Harbor and River Engineering National Taiwan Ocean University Keelung Taiwan

本研究针对结合微孔隙水压力计改良型GR试验系统与一般GR试验系统进行了一系列的试验分析比较,研究中所使用的试验材料包含4种不同针轧不织布及5种不同比例渥太华砂与风化泥岩混合土壤。试验结果发现,由改良型GR试验系统所得的GR试验值... 详细信息

本研究针对结合微孔隙水压力计改良型GR试验系统与一般GR试验系统进行了一系列的试验分析比较,研究中所使用的试验材料包含4种不同针轧不织布及5种不同比例渥太华砂与风化泥岩混合土壤。试验结果发现,由改良型GR试验系统所得的GR试验值都高于一般GR试验系统所得结果,同时也验证了微孔隙水压力计在GR试验系统中可提供较好的孔隙水压力量测与抗阻塞潜势评估。

关键词：孔隙水压力试验系统试验材料风化试验分析泥岩分析研究微孔隙发现试验结果

Secular decreasing trends in gastric cancer incidence in Taiwan:A population-based cancer registry study

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World Journal of Gastroenterology 2021年第34期27卷 5764-5774页

作者： yen-Tzeng Lin Chun-Ju Chiang Ya-Wen Yang Shih-Pei Huang San-Lin You School of Medicine College of MedicineFu Jen Catholic UniversityNew Taipei City 242008TaiwanChina Institute of Epidemiology and Preventive Medicine College of Public HealthNational Taiwan UniversityTaipei 10617TaiwanChina Department of Medical Education&Bioethics Graduate Institute of Medical Education&BioethicsNational Taiwan University College of MedicineTaipei 10051TaiwanChina School of Medicine&Big Data Research Center Fu Jen Catholic UniversityNew Taipei City 242008TaiwanChina

BACKGROUND Gastric cancer remains a leading cause of cancer death *** Taiwan,gastric cancer is the sixth leading cause of cancer mortality in both males and *** To evaluate secular trends in gastric cancer incidence according to age,sex,and Helicobacter pylori(***)treatment in *** In this population-based study,we used the national Taiwan Cancer Registry *** percent changes in incidence rates were used to describe secular trends in incidence rates and sex ratios of gastric cancer in ***’s product-moment correlation coefficients were used to analyze the correlation between annual age-adjusted incidence rates and the annual number of patients treated with antibiotic therapy for *** *** The annual percent changes showed continuously decreasing rates of gastric cancer among both males and ***,the decreasing trends differed by sex,with an annual percent change of-2.58%in males and-2.14%in *** age-specific incidence rates increased with *** the same age group,more recent time periods showed lower incidence rates than greater time ***,the sex ratio was lower in later birth cohorts than in earlier birth ***-adjusted incidence rates substantially decreased with increasing numbers of patients being treated with antibiotic therapy for *** infection during 2005 to 2016(r=0.72).CONCLUSION We observed steadily decreasing trends with differential sex ratios in the incidence of gastric cancer in *** results support *** eradication programs in Taiwan.

关键词： Gastric cancer Population-based study Taiwan Cancer Registry Sex difference Helicobacter pylori Helicobacter pylori eradication

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串扰目标识别框架

计算机工程与应用 2006年第30期42卷 72-77页

作者：张富彬李长青 Ching-yen Ho 彭思龙中国科学院自动化研究所国家专用集成电路设计工程研究中心 Synopsys Inc.Mountain View CA 94043

提出了一个全面识别静态和动态串扰噪声的算法框架,在静态串扰噪声的识别中,通过静态串扰噪声的峰值以及噪声宽度信息来识别串扰目标。在动态串扰噪声的识别中,引入了混合时序分析,缩小了时间窗区间,并通过测试生成来验证信号间的逻辑关... 详细信息

提出了一个全面识别静态和动态串扰噪声的算法框架,在静态串扰噪声的识别中,通过静态串扰噪声的峰值以及噪声宽度信息来识别串扰目标。在动态串扰噪声的识别中,引入了混合时序分析,缩小了时间窗区间,并通过测试生成来验证信号间的逻辑关系,通过这些准确的时序及逻辑信息,识别出串扰目标。

关键词：静态串扰噪声动态串扰噪声串扰识别混合时序分析测试生成

Treatment efficacy for patients with chronic hepatitis C and preexisting hepatocellular carcinoma by directly acting antivirals

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Hepatoma Research 2020年第4期6卷 30-38页

作者： Chia-yen Dai Chung-Feng Huang Meng-Hsuan Hsieh Ching-I Huang Ming-Lun Yeh Pei-ChienTsai Ching-Chih Lin Meng-Szu Lee Jeng-fu Yang Po-Yao Hsu Yu-Ju Wei Cheng-Ting Hsu Po-Cheng Liang Yi-Hung Lin Jee-fu Huang Wan-Long Chuang Ming-Lung Yu Hepatobiliary Division Department of Internal MedicineKaohsiung Medical University HospitalKaohsiung Medical UniversityKaohsiung 807Taiwan Health Management Center&Department of Community Medicine Kaohsiung Medical University HospitalKaohsiung Medical UniversityKaohsiung 807Taiwan Faculty of Internal Medicine College of MedicineKaohsiung Medical UniversityKaohsiung 807Taiwan Department of Biological Science and Technology College of Biological Science and TechnologyNational Chiao Tung UniversityHsin-ChuKaohsiung 807Taiwan

Aim:Despite the high cure rate of interferon-free directly acting antivirals(DAAs)for chronic hepatitis C(CHC)patients,the treatment efficacy for patients with preexisting hepatocellular carcinoma(HCC)remains *** aimed in the present study to address the issue by using novel DAAs in treating CHC patients who were adherent to treatment in ***:CHC patients with or without HCC were consecutively *** primary objective was sustained virological response(SVR)defined as undetectable HCV RNA throughout 12 weeks of a post-treatment follow-up period(SVR12).Only patients with available SVR12 were enrolled for final ***:A total of 1237 patients(1113 non-HCC,101 inactive HCC and 23 active HCC)were *** overall SVR12 rate was 98.9%,and was similar between HCV patients with and without pre-existing HCC(98.4%vs.98.9%,P=0.64).While HCC patients were classified as those who had active or inactive HCC,the SVR12 was also similar between patients with and without active HCC(95.7%vs.99.0%,P=0.34).Among the 101 patients without viable HCC at the time of DAA initiation,eighty-four patients exhibited curative therapy and the other 17 ;patients experienced HCC recurrence before *** the 23 patients with viable HCC at the time of DAA treatment,10 patients had received curative therapy for HCC whereas the remaining 13 patients had HCC that was never *** SVR12 rates were also similar among the four subpopulations,being 98.8%(83/84),100%(17/17),90%(9/10)and 100%(13/13)***:CHC patients with HCC who were adherent to potent DAAs achieved similar SVR12 rate compared to those without HCC and could be effectively treated.

关键词： Directly acting antiviral chronic hepatitis C hepatitis C virus hepatocellular carcinoma sustained virological response

The Chromosomal Effect of Birchen Dust as Determined by the Micronucleus Test

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Biomedical and Environmental Sciences 1997年第4期10卷 396-401页

作者： JIANG ZHI-CHENG SU YI-LAN DENG YI-fu SUN WEI LIU WEI-CHENG WEI DAI-MING YAN JIU-yen YAO YU-LONGn(Deprtment of Occupotional Health, Chpital University ofMedical Sciences, Beijing, 100054, China)(Sanitationand Anti-ePidemic Station, tongiingcheng Fore Department of Occupational Health Capital University of Medical Sciences Beijing 100054 China Sanitation and Anti-epidemic Station Dongjingcheng Forestry Agency Heilongjiang Province China Department of Health Mudanjiang Forestry Agency Heilongjiang Province China

In a wood processing factory, the measured air concentration of birchen dust was 1. 26 ±0. 41 mg/m3, and the micronucleus frequency of peripheral blood lymphocytes in 83 workersexposed to wood dust was 1. 13 ± 2. 83%, which was significantly higher (P 0. 05 ). The micronucleus test in mice treated with waterextracts of unsteamed and unbaked birchen dust showed that the micronucleus frequencies inall treated groups were significantly higher than that of contro group (P < 0. 01 ) and therewas also a doseresponse correlation (r = 0. 96, P < 0. 0005 ). The results of steamed andbaked birchen dust extracts were significantly lower than those of the unsteamed and unbakedones at the same doses (P< 0. 001 ). This suggests that when the birchen dust is steamed atthe temperature of 100℃ for 24h or baked at the temperature of 80℃, its inducing effect inmicronucleus test could be lowered

关键词： The Chromosomal Effect of Birchen Dust as Determined by the Micronucleus Test Chen

Motivations for Loan Herding by Chinese Banks and Its Impact on Bank Performance

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China & World Economy 2019年第4期27卷 29-52页

作者： Hao Fang yen-Hsien Lee Chung-Hua Shen Chien-Ping Chung School of Economics Qu Fu Normal University China Department of Finance Chung Yuan Christian University Taiwan China College of Management National Taiwan University of Science and Technology Taiwan China

This study uses a dynamic herding model that considers intertemporal and crosssectional correlation to confirm that loan herding occurs among joint-stock commercial banks (JSCBs) and city commercial banks (CCBs). We clarify the motivations for bank loan herding. We find that loan herding by both JSCBs and CCBs results more from following the behavior of other same-type banks than different-type banks because of characteristic herding or reputational concerns. Loan herding by JSCBs is motivated by investigative herding, whereas loan herding by CCBs results from informational cascades. Moreover, loan herding has a significantly harmful impact on the operating performance of CCBs but not JSCBs, which may be explained by the irrational behavior of CCBs. Our results will help Chinese bank supervisors develop appropriate policies for handling loan herding.

关键词： financial crisis irrational herding loan herding

Predicting portal venous anomalies by left-sided gallbladder or rightsided ligamentum teres hepatis: A large scale, propensity scorematched study

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World Journal of Gastroenterology 2023年第27期29卷 4344-4355页

作者： Hsuan-Yin Lin Rheun-Chuan Lee Jyh-Wen Chai Chiann-Yi Hsu yen Chou Hsuen-En Hwang Chien An Liu Nai-Chi Chiu Ho-Hsian yen Department of Radiology Taichung Veterans General HospitalTaichung 407219Taiwan Department of Radiology Taipei Veterans General HospitalTaipei 11267Taiwan School of Medicine National Yang Ming Chiao Tung UniversityTaipei 112Taiwan Department of Medical Research Taichung Veterans General HospitalTaichung 40705Taiwan Department of Radiology Fu Jen Catholic University HospitalTaipei 24352Taiwan Department of Radiology Far Eastern Memorial HospitalNew Taipei City 220Taiwan

BACKGROUND Right-sided ligamentum teres(RSLT)is often associated with portal venous anomalies(PVA)and is regarded as a concerning feature for hepatobiliary *** studies consider RSLT to be one of the causes of left-sided gallbladder(LGB),leading to the hypothesis that LGB must always be present with ***,some cases have shown that right-sided gallbladder(RGB)can also be present in livers with *** To highlight the rare variation that RSLT may not come with LGB and to determine whether ligamentum teres(LT)or gallbladder location is reliable to predict *** This study retrospectively assessed 8552 contrast-enhanced abdominal computed tomography examinations from 2018 to 2021[4483 men,4069 women;mean age,59.5±16.2(SD)years].We defined the surrogate outcome as major *** cases were divided into 4 subgroups according to gallbladder and LT *** one hand,we analyzed PVA prevalence by LT locations using gallbladder location as a controlled variable(n=36).On the other hand,we controlled LT location and computed PVA prevalence by gallbladder locations(n=34).Finally,we investigated LT location as an independent factor of PVA by using propensity score matching(PSM)and inverse probability of treatment weighting(IPTW).RESULTS We found 9 cases of RSLT present with *** the LGB cases,RSLT is associated with significantly higher PVA prevalence than typical LT[80.0%vs 18.2%,P=0.001;OR=18,95%confidence interval(CI):2.92-110.96].When RSLT is present,we found no statistically significant difference in PVA prevalence for RGB and LGB cases(88.9%vs 80.0%,P>0.99).Both PSM and IPTW yielded balanced cohorts in demographics and gallbladder *** RSLT group had a significantly higher PVA prevalence after adjusted by PSM(77.3%vs 4.5%,P<0.001;OR=16.27,95%CI:2.25-117.53)and IPTW(82.5%vs 4.7%,P<0.001).CONCLUSION RSLT doesn't consistently coexist with *** can predict PVA independently while the gallbladder location does not serve as a suf

关键词： Right-sided ligamentum teres Left-sided gallbladder Portal venous anomalies Inverse probability of treatment weighting Average treatment effect in the treated