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Efficacy and safety of electroacupuncture for insomnia:A systematic review and meta-analysis

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Journal of Integrative Medicine 2024年第4期22卷 459-472页

作者： Han-yu Xu Lin-na Wu Yuan Zhang te Ba Xiao-feng Zhao Acupuncture and Moxibustion Department First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300193China National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion Tianjin 300193China

Background:Electroacupuncture is often used to treat ***:To evaluate the efficacy and safety of electroacupuncture for *** strategy:Databases including PubMed,Cochrane Library,Embase,Web of Science,Chinese Biomedical Literature Database,China National Knowledge Infrastructure,Wanfang Data and VIP Fulltext e-Journals Database were searched up to January 15,*** criteria:Randomized clinical trials were included if they compared the clinical efficacy and safety of electroacupuncture with sham acupuncture,no treatment or usual care (UC) and general *** extraction and analysis:The full texts of the studies were reviewed to remove ineligible *** extracted data included authors,publication year,diagnostic criteria,sample size,population characteristics,interventions and *** above steps were performed independently by two reviewers and the data were cross ***15.0 software was used to analyze the extracted outcome *** continuous data (Pittsburgh Sleep Quality Index[PSQI]score and Insomnia Severity Index score),weighted mean difference (WMD) was calculated and 95% confidence interval (CI) was reported when the same scale was *** dichotomous variables (clinical response rate and adverse events),a meta-analysis was performed using risk ratio (RR) as the effect ***:Thirty-one trials with 2226 subjects were *** meta-analysis suggested that electroacupuncture was more effective in improving insomnia compared with the control group (sham acupuncture,no treatment,UC and general acupuncture)(RR=1.21;95 CI:[1.16,1.27]),significantly reducing the PSQI score in insomnia patients after treatment and at follow-up (WMD=-3.23;95%CI:[-4.29,-2.17];P<0.001).There was no significant difference in the incidence of adverse events between the EA and control groups (sham acupuncture and no treatment or ***=1.48;95%CI:[0.91,2.40];P=0.117).In addition,the regression results revealed t

关键词： Electroacupuncture Insomnia Systematic review Meta-analysis

Optical trapping-enhanced probes designed by a deep learning approach

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Photonics Research 2024年第5期12卷 959-968页

作者： MIAO PENG GUANGZONG XIAO XINLIN CHEN te DU teNGFANG KUANG XIANG HAN WEI XIONG GANGYI ZHU JUNBO yang ZHONGQI TAN KAIYONG yang HUI LUO College of Advanced Interdisciplinary Studies National University of Defense TechnologyChangsha 410073China College of Electronic Information and Physics Central South University of Forestry and TechnologyChangsha 410004China Nanhu Laser Laboratory National University of Defense TechnologyChangsha 410021China Center of Material Science National University of Defense TechnologyChangsha 410073China College of Communication and Information technology Nanjing University of Posts and TelecommunicationsNanjing 210003China

Realizing optical trapping enhancement is crucial in biomedicine,fundamental physics,and precision *** the metamaterials with artificially engineered permittivity as photonic force probes in optical tweezers will offer unprecedented opportunities for optical trap ***,it usually involves multi-parameter optimization and requires lengthy calculations;thereby few studies remain despite decades of research on optical ***,we introduce a deep learning(DL)model to attack this *** DL model can efficiently predict the maximum axial optical stiffness of Si∕Si_(3)N_(4)(SSN)multilayer metamaterial nanoparticles and reduce the design duration by about one order of *** experimentally demonstrate that the designed SSN nanoparticles show more than twofold and fivefold improvement in the lateral(k_(x)and k_(y))and the axial(k_(z))optical trap stiffness on the high refractive index amorphous TiO_(2)*** the DL model in optical manipulation systems will expedite the design and optimization processes,providing a means for developing various photonic force probes with specialized functional behaviors.

关键词： trapping optimization stiffness

miRNA-26a抑制ox-LDL介导的HAECs凋亡作用的机制研究

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重庆医学 2016年第36期45卷 5052-5055页

作者：李勇杨特沈怡重庆市中医院心血管内科 400011

目的探究miR-26a在ox-LDL介导内皮细胞HAECs凋亡中的作用及其调控机制。方法采用不同浓度的氧化低密度脂蛋白(ox-LDL)在体外作用于HAECs细胞,噻唑蓝(MTT)和TUNEL染色检测ox-LDL作用HAECs后细胞的活性与凋亡率,定量实时聚合酶链反应(qRT-... 详细信息

目的探究miR-26a在ox-LDL介导内皮细胞HAECs凋亡中的作用及其调控机制。方法采用不同浓度的氧化低密度脂蛋白(ox-LDL)在体外作用于HAECs细胞,噻唑蓝(MTT)和TUNEL染色检测ox-LDL作用HAECs后细胞的活性与凋亡率,定量实时聚合酶链反应(qRT-PCR)检测ox-LDL作用HAECs后细胞中miR-26a的表达水平。在HAECs中过表达miR-26amimic,MTT和TUNEL染色检测ox-LDL作用后细胞的活性和凋亡率。构建荧光素酶报告载体pMIR-PteN的3′UTR,利用荧光素酶活性检测鉴定miR-26a的预测靶基因。qRT-PCR和蛋白质印迹法(Western blot)分别检测PteN的mRNA和蛋白表达水平。结果 ox-LDL能够介导HAECs细胞的毒性死亡和细胞凋亡,并且降低了HAECs细胞中miR-26a的表达水平。过表达miR-26amimic能够抑制ox-LDL作用HAECs后细胞的毒性和凋亡。转染miR-26amimic显著抑制荧光素酶的活性(PteN的mRNA和蛋白表达水平(PteN的表达。miR-26a可能成为治疗凋亡相关的动脉粥样硬化的潜在靶点。

关键词：微RNAs 人类主动脉内皮细胞第10号染色体缺失的磷酸酶和张力蛋白同源基因细胞凋亡动脉粥样硬化

网络规模对创业资源获取的影响:创业者先前经验的调节作用

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科技进步与对策 2018年第2期35卷 1-9页

作者：杨特赵文红周密西安交通大学管理学院陕西西安710049

通过对165家新创企业问卷调查,实证检验创业者网络规模与新创企业资源获取之间的关系,同时研究创业者不同先前经验的调节作用。结果表明,创业网络规模与新创企业资源获取之间呈倒U型关系;不同类别的先前经验会对这一关系产生不同的调节... 详细信息

通过对165家新创企业问卷调查,实证检验创业者网络规模与新创企业资源获取之间的关系,同时研究创业者不同先前经验的调节作用。结果表明,创业网络规模与新创企业资源获取之间呈倒U型关系;不同类别的先前经验会对这一关系产生不同的调节作用;先前创业经验对倒U型关系具有正向调节作用,而先前行业经验和先前管理经验则具有负向调节作用。最后,提出创业者网络规模管理建议和先前经验培养管理建议,以期丰富现有研究成果。

关键词：网络规模创业资源先前经验

创业者先前经验、战略导向与创业企业商业模式创新关系研究

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管理学报 2021年第7期18卷 1022-1031,1106页

作者：李颖赵文红杨特西安交通大学管理学院西安市710049

基于管理认知能力视角,探讨先前经验对创业企业商业模式创新的影响。引入创业导向、市场导向与风险感知变量考察了这一影响过程的中介机制与作用边界。利用386家创业企业数据进行实证检验,研究表明:(1)先前经验显著促进创业企业商业模... 详细信息

基于管理认知能力视角,探讨先前经验对创业企业商业模式创新的影响。引入创业导向、市场导向与风险感知变量考察了这一影响过程的中介机制与作用边界。利用386家创业企业数据进行实证检验,研究表明:(1)先前经验显著促进创业企业商业模式创新;(2)创业导向与市场导向在先前经验与创业企业商业模式创新中发挥中介作用;(3)风险感知弱化了通过创业导向的间接效应;(4)风险感知强化了通过市场导向的间接效应。

关键词：先前经验商业模式创新创业导向市场导向风险感知

蜂窝网络下的SWIPT-D2D通信资源分配

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中国科学院大学学报（中英文） 2022年第6期39卷 845-852页

作者：杨特洪佩琳李润洲中国科学技术大学信息网络实验室合肥230027

无线信息与能量同步传输(SWIPT)作为一种重要的射频能量采集技术,可使能量受限设备在通信的同时采集射频能量补充电能。针对蜂窝网络下的设备到设备(D2D)通信系统,研究D2D接收端利用功率切片技术同时进行信息解码与射频能量采集时的资... 详细信息

无线信息与能量同步传输(SWIPT)作为一种重要的射频能量采集技术,可使能量受限设备在通信的同时采集射频能量补充电能。针对蜂窝网络下的设备到设备(D2D)通信系统,研究D2D接收端利用功率切片技术同时进行信息解码与射频能量采集时的资源分配问题。为保证D2D接收端在高射频能量采集需求下的高信息解码速率,提出D2D通信一对多的频谱复用方案,允许D2D设备复用多个蜂窝上行链路频谱进行通信,网络中的所有用户设备作为分布式的射频能量来源对D2D接收端充电。在此场景下,对包括频谱匹配,功率控制和功率切片控制在内的系统资源分配进行联合优化,在保证D2D接收端射频能量采集需求和各通信链路速率需求条件下最大化D2D通信总速率。以上优化问题为非凸形式的混合整数非线性规划(MINLP)问题,难以求得最优解。因此基于贪心思想和凸逼近理论提出两层资源分配算法。仿真结果显示,该算法对比其他资源分配策略,在满足用户设备能量和速率需求前提下显著提升了D2D通信总速率。

关键词： D2D通信 SWIPT 射频能量采集资源分配

Flexible head-following motion planning for scalable and bendable continuum robots

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Biomimetic Intelligence & Robotics 2024年第2期4卷 86-96页

作者： te Li Guoqing Zhang Xinyuan Li Xu Li Haibo Liu Yongqing Wang State Key Laboratory of High-performance Precision Manufacturing School of Mechanical EngineeringDalian University of TechnologyDalian 116023China

Continuum robots,which are characterized by high length-to-diameter ratios and flexible structures,show great potential for various applications in confined and irregular *** to the combination of motion modes,the existence of multiple solutions,and the presence of complex obstacle constraints,motion planning for these robots is highly *** tackle the challenges of online and flexible operation for continuum robots,we propose a flexible head-following motion planning method that is suitable for scalable and bendable continuum ***,we establish a piecewise constant curvature(PCC)kinematic model for scalable and bendable continuum *** article proposes an adaptive auxiliary points model and a method for updating key nodes in head-following motion to enhance the precise tracking capability for paths with different ***,the article integrates the strategy for adjusting the posture of local joints of the robot into the head-following motion planning method,which is beneficial for achieving safe obstacle avoidance in local *** article concludes by presenting the results of multiple sets of motion simulation experiments and prototype *** study demonstrates that the algorithm presented in this paper effectively navigates and adjusts posture to avoid obstacles,meeting the real-time demands of online *** average time for a single-step solution is 4.41×10^(-5) s,and the average tracking accuracy forcircular paths is 7.8928mm.

关键词： Continuum robot Motion planning Scalable and bendable Head-following

Energy spectrum computed tomography multi-parameter imaging in preoperative assessment of vascular and neuroinvasive status in gastric cancer

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2511-2520页

作者： Jing Wang Jian-Cheng Liang Fa-te Lin Jun Ma Department of Radiology Pingluo County People's HospitalShizuishan 753400Ningxia Hui Autonomous RegionChina Department of Gastrointestinal Surgery Jiangsu Provincial People's HospitalNanjing 210029Jiangsu ProvinceChina

BACKGROUND Vascular and nerve infiltration are important indicators for the progression and prognosis of gastric cancer(GC),but traditional imaging methods have some limitations in preoperative *** recent years,energy spectrum computed tomography(CT)multiparameter imaging technology has been gradually applied in clinical practice because of its advantages in tissue contrast and lesion detail *** To explore and analyze the value of multiparameter energy spectrum CT imaging in the preoperative assessment of vascular invasion(LVI)and nerve invasion(PNI)in GC *** Data from 62 patients with GC confirmed by pathology and accompanied by energy spectrum CT scanning at our hospital between September 2022 and September 2023,including 46 males and 16 females aged 36-71(57.5±9.1)years,were retrospectively *** patients were divided into a positive group(42 patients)and a negative group(20 patients)according to the presence of LVI/*** CT values(CT40 keV,CT70 keV),iodine concentration(IC),and normalized IC(NIC)of lesions in the upper energy spectrum CT images of the arterial phase,venous phase,and delayed phase 40 and 70 keV were measured,and the slopes of the energy spectrum curves[K(40-70)]from 40 to 70 keV were *** Core Tip:To investigate the application value of multiparameter energy spectrum computed tomography(CT)imaging in the preoperative assessment of vascular and nerve infiltration in patients with gastric cancer(GC).The imaging data of GC patients were retrospectively analyzed to evaluate the accuracy and sensitivity of CT for identifying and quantifying vascular and nerve infiltration and for comparison with postoperative pathological *** purpose of this study was to verify the clinical feasibility and potential advantages of multiparameter energy spectrum CT imaging in guiding preoperative diagnosis and treatment decision-making and to provide a new imaging basis for improving the diagnostic accuracy

关键词： Tomography X-ray computer Energy spectrum computed tomography Gastric cancer Vascular invasion Nerve invasion Cross-sectional study

Enhanced Ion-Selective Diffusion Achieved by Supramolecular Interaction for High Thermovoltage and Thermal Stability

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Energy & Environmental Materials 2024年第2期7卷 200-208页

作者： Jiale Ke Xing Zhao Jie yang Kai Ke Yu Wang Mingbo yang Wei yang College of Polymer Science and Engineering Sichuan UniversityState Key Laboratory of Polymer Materials EngineeringChengdu 610065China

Thermoelectric(te)generators capable of converting thermal energy into applicable electricity have gained great popularity among emerging energy conversion ***-based ionic thermoelectric(i-te)materials are promising candidates for energy conversion systems because of their wide sources,innocuity,and low manufacturing ***,common physically crosslinked biopolymer gels induced by single hydrogen bonding or hydrophobic interaction suffer from low differential thermal voltage and poor thermodynamic ***,we develop a novel i-te gel with supramolecular structures through multiple noncovalent interactions between ionic liquids(ILs)and gelatin molecular *** thermopower and thermoelectric power factor of the ionic gels are as high as 2.83 mV K-1 and 18.33μW m^(-1)K^(-2),*** quasi-solid-state gelatin-[EMIM]DCA i-te cells achieve ultrahigh 2 h output energy density(E_(2h)=9.9 mJ m^(-2))under an optimal temperature ***,the remarkable stability of the supramolecular structure provides the i-te hydrogels with a thermal stability of up to 80℃.It breaks the limitation that biopolymer-based i-te gels can only be applied in the low temperature range and enables biopolymer-based i-te materials to pursue better performance in a higher temperature range.

关键词： biopolymer gel ionic liquid multiple noncovalent interactions supramolecular structure thermoelectric conversion