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An Effective Diagnosis System for Brain Tumor Detection and Classification

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Computer Systems Science & Engineering 2023年第8期46卷 2021-2037页

作者： Ahmed A.Alsheikhy ahmad S.Azzahrani A.Khuzaim Alzahrani tawfeeq Shawly Electrical Engineering Department College of EngineeringNorthern Border UniversityArar91431Saudi Arabia Department of Medical Laboratory Technology Faculty of Applied Medical SciencesNorthern Border UniversityArar91431Saudi Arabia Electrical Engineering Department Faculty of Engineering at RabighKing Abdulaziz UniversityJeddah21589Saudi Arabia

A brain tumor is an excessive development of abnormal and uncontrolled cells in the *** growth is considered deadly since it may cause *** brain controls numerous functions,such as memory,vision,and *** to the location,size,and shape of these tumors,their detection is a challenging and complex *** efforts have been conducted toward improved detection and yielded promising results and ***,the accuracy should be higher than what has been *** paper presents a method to detect brain tumors with high *** method works using an image segmentation technique and a classifier in *** utilized classifier is a SupportVector Machine(SVM).DiscreteWavelet Transform(DWT)and Principal Component Analysis(PCA)are also involved.A dataset from the Kaggle website is used to test the developed *** obtained results reached nearly 99.2%of *** paper provides a confusion matrix of applying the proposed approach to testing images and a comparative evaluation between the developed method and some works in the *** evaluation shows that the presented system outperforms other approaches regarding the accuracy,precision,and *** research discovered that the developed method is extremely useful in detecting brain tumors,given the high accuracy,precision,and recall *** proposed system directs us to believe that bringing this kind of technology to physicians diagnosing brain tumors is crucial.

关键词： Brain tumor classification support vector machine artificial intelligence image segmentation tumor detection

Comparative Evaluation of Different Treatment for Purulent Wounds in Dogs

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Open Journal of Veterinary Medicine 2016年第7期6卷 119-126页

作者： ahmad Massoud Niazi Mohammad Monir tawfeeq Amanullah Aziz Jahid Zabuli Shahpoor Rahmati Abdul Razaq Irshad Clinic Department Faculty of Veterinary Science Kabul University Kabul Afghanistan

To compare the healing of purulent wounds with Shilajit dressing vs. Vishnevsky dressing in dogs with purulent wounds of >2 weeks of duration, eight dogs were chosen from same ages in two groups i.e., Shilajit and Vishnevsky dressing group. Dressing was done on every day basis for more than two weeks of follow up period. Main outcome of healing measure was completed at three weeks. Wound healing status was assessed at three days intervals till end of three weeks. Shilajit treated achieved complete decrease in the wound surface area, effect of healing score in Shilajit dressing group in comparison to the Vishnevsky dressing group at p > 0.05 level of significance. Shilajit is highly effective in achieving a characteristic feature of regenerative and granulation healing of purulent wounds as compared to Vishnevsky dressing group in dogs.

关键词： Shilajit Wound Dressing Purulent Wound of Dog Granulation Tissue

Clinical Features of Post-Parturient Hemoglobinuriain Dairy Cattle and Buffaloes: A Review

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Open Journal of Veterinary Medicine 2021年第4期11卷 143-155页

作者： Shahpoor Rahmati Amanullah Aziz M. Monir tawfeeq Jahed Zabuli Sayed ahmad Nazhat Clinic Department Faculty of Veterinary Science Kabul University Kabul Afghanistan

Postpartum hemoglobinuria (PPH) is a sporadic noninfectious syndrome which normally seen in bovine around the world. PPH is most commonly affecting high-productive cows and buffaloes during the early pregnancy and early lactation period. PPH stands as a serious threat to the dairy cattle and buffaloes in Afghanistan, Pakistan, and India, affecting a considerable number of animals every year. It is characterized by hemoglobinuria, intravenous hemolysis, severe anemia, and death due to anemia and hypoxia. However, the exact mechanism of the mentioned illness is not completely understood. Lots of comprehensive studies have been done and/or still are in progress in order to find the exact causes of intravascular hemolysis that is responsible for hemoglobinuria in the mentioned disease. But, hypophosphatemia in the high productive milking cows during the early stage of milk production is widely confident to be associated with PPH. In different parts of the world, many risk factors had been reported to be associated with PPH. Decreasing the level of phosphorous in blood serum, interrupted the phospholipid layers of red blood cells resulting in hemoglobinuria, a decrease in milk production, anorexia, and the death of animals in the cause i

关键词： Hypophosphatemia Anemia Post-Partum Hemoglobinuria Cattle and Buffalo

Inhibitory Effects of Several Fluoroquinolones on Feline CYP1A and 3A in Hepatic Microsomes

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Open Journal of Veterinary Medicine 2020年第12期10卷 219-237页

作者： Syed Sher Shah Sadaat Nasrin Stankzi Mohammad Monir tawfeeq Farid ahmad Tanin Amanullah Aziz Kazuki Sasaki Department of Clinic Faculty of Veterinary Science Kabul University Kabul Afghanistan Department of Pre Clinic Faculty of Veterinary Science Kabul University Kabul Afghanistan Department of Veterinary Medicine Faculty of Agriculture Tokyo University of Agriculture and Technology Tokyo Japan

In this study, the effects of several fluoroquinolones (FQs), such as Ciprofloxacin (CPFX);Orbifloxacin (OBFX);Norfloxacin (NFX);Ofloxacin (OFX);and Enerofloxacin (EFX) on activities of both Cytochrome P450 1A (CYP1A) and Cytochrome P450 3A (CYP3A) of feline microsomes by in vitro tests were studied. Ethoxyresorufin O-deethylation (EROD) and Midazolam 1' hydroxylation and 4-hydroxylation (MDZ1'H and MDZ4H) were analyzed by High Performance Liquid Chromatography (HPLC). All the FQs inhibited the reactions by a competitive or noncompetitive and irreversible manner. The inhibitory constants (Ki) were as followings: CYP1A;ranged from 0.12 to 1.23 mM for NFX, OBFX, EFX, CPFX, OFX and CYP3A, for MDZ1'H;ranged from 5.8 to 35 and MDZ4H;9 to 29 mM, respectively. As these values are higher by 24 to 200-times of given single clinical dose of serum levels after application of FQs. It indicates that if co-administrated with these FQs by reversible inhibitory manner, the inhibition of CYP1A and CYP3A effect on CYP1A and 3A actions is not very significant to cause drug interaction with above mentioned enzyme substrates. Out of the FQs tested, CPFX and NFX for CYP1A, and CPFX for CYP3A showed irreversible inhibitory effects (time-dependent), so it has been concluded that these drugs may cause drug-drug interaction by accumulation, when they are repeatedly administrated. Since EFX is biotransformed to CPFX by the liver, it could have the identical risk too.

关键词： Several Fluoroquinolones CYP Inhibitors EROD Midazolam Microsomes

Inhibitory Effects of Several Fluoroquinolones on Feline CYP1A and 3A in Hepatic Microsomes

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