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Structure and heterogeneity of habitat determine diet of predators despite prey abundance:Similar response in Long-eared,Short-eared Owls and Common Kestrels

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Avian Research 2023年第1期14卷 54-61页

作者： tatyana Kovinka Alexander Sharikov tatyana Massalskaya Sergey Volkov Zoology and Ecology Department Moscow State Pedagogical UniversityKibalchicha Str.6-3129164MoscowRussid Severtsov Institute of Ecology and Evolution Russian Academy of SciencesMoscow119071Russia

According to one of the theses of optimal foraging theory,main prey species abundance in the hunting area is the main factor determining the diet and habitat choices of birds of *** other factors can also be *** habitat structure influences the predators’diets as *** this study we examined the influence of habitat structure on diet compositions of three species of birds:Long-eared Owl(Asio otus),Short-eared Owl(***)and Common Kestrel(Falco tinnunculus).The study was carried out from 2007 to 2019 in a 48 km2area of the Crane’s Homeland Reserve,Moscow Region,*** habitat structures of model species’hunting territories(ratio of different types of landscape elements)were classified in module"Semi-Automatic Classification Plugin"based on the QgIS.A boosted regression tree analysis identified that the share of the main prey species in the diet is primarily determined by the landscape structure of hunting *** largest share of Common Vole(Microtus arvalis)in birds’diet was determined by the shrubs area(15%of hunting area),the meadow area(75%),the habitat heterogeneity(70%)and the arable land area(5%).The same predictors determined the largest share of Root Vole(Microtus oeconomus):the shrubs area 25%,the meadow area 70%,and the arable land area 3%.The annual mean abundance of prey species did not determine their importance in the diet of birds of ***,the main prey abundance in the hunting area is not a determining factor for the formation of diet composition of birds of prey.

关键词： Birds of prey diet Boosted regresion tnee Habitat strnocture efiect Prey sbundance

Influence of 10-(6-plastoquinonyl) decyltriphenylphosphonium on free-radical homeostasis in the heart and blood serum of rats with streptozotocin-induced hyperglycemia

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World Journal of Diabetes 2019年第12期10卷 546-559页

作者： Aleksander A Agarkov tatyana N Popova Yana g Boltysheva Department of Medical Biochemistry and Microbiology Voronezh State University

BACKgROUND It is known that under conditions of tissue tolerance to insulin,observed during type 2 diabetes mellitus(DM2),there is an increased production of reactive oxygen ***,the free radicals can initiate lipid peroxidation(LPO)in lipoprotein *** concentration of LPO products can influence the state of insulin receptors,repressing their hormone connection activity,which is expressed as a reduction of the glucose consumption by *** is possible that reduction in glucose concentration during administration of 10-(6-plastoquinonyl)decyltriphenylphosphonium(SkQ1)to rats with DM2 may be related to the antioxidant properties of this *** To establish the influence of SkQ1 on free-radical homeostasis in the heart and blood serum of rats with streptozotocin-induced *** To induce hyperglycemia,rats were fed a high-fat diet for 1 mo and then administered two intra-abdominal injections of streptozotocin with a 7-d interval at a 30 mg/kg of animal weight dose with citrate buffer equal to pH ***1 solution was administered intraperitoneally at a 1250 nmol/kg dose per *** samples were taken from control animals,animals with experimental hyperglycemia,rats with streptozotocin-induced glycemia that were administered SkQ1 solution,animals housed under standard vivarium conditions that were administered SkQ1,rats that were administered intraperitoneally citrate buffer equal to pH 4.4 once a week during 2 wk after 1-mo high-fat diet,and animals that were administered intraperitoneally with appropriate amount of solution without SkQ1(98%ethanol diluted eight times with normal saline solution).To determine the intensity of free radical oxidation and total antioxidant activity,we used the biochemiluminescence *** hydratase(AH),superoxide dismutase,and catalase activities were estimated using the Hitachi U-1900 spectrophotometer supplied with *** amount of citrate was determined by means of the Natel

关键词： Diabetes mellitus Free radical oxidation Antioxidants 10-(6-plastoquinonyl)decyltriphenylphosphonium

CRITICAL ISSUES IN THE NUMERICAL TREATMENT OF THE PARAMETER ESTIMATION PROBLEMS IN IMMUNOLOgY

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Journal of Computational Mathematics 2012年第1期30卷 59-79页

作者： tatyana Luzyanina gennady Bocharov Institute of Mathematical Problems in Biology RAS Pushchino Moscow reg. Russia Institute of Numerical Mathematics RAS Moscow Russia

A robust and reliable parameter estimation is a critical issue for modeling in immunology. We developed a computational methodology for analysis of the best-fit parameter estimates and the information-theoretic assessment of the mathematical models formulated with ODEs. The core element of the methodology is a robust evaluation of the first and second derivatives of the model solution with respect to the model parameter values. The critical issue of the reliable estimation of the derivatives was addressed in the context of inverse problems arising in mathematical immunology. To evaluate the first and second derivatives of the ODE solution with respect to parameters, we implemented the variational equations-, automatic differentiation and complex-step derivative approximation methods. A comprehensive analysis of these approaches to the derivative approximations is presented to understand their advantages and limitations.

关键词： Mathematical modeling in immunology Parameter estimation Constrainedoptimization.

Cell-based therapies for neural replacement strategies in stroke-related neurodegeneration： neurophysiological insights into stem progenitor cell neurogenesis within a host environment

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Neural Regeneration Research 2018年第8期13卷 1350-1351页

作者： Olga Kopach tatyana Pivneva Department of Clinical and Experimental Epilepsy Institute of NeurologyUniversity College London London UK Department ot Sensory Signalling Bogomoletz Institute oI Physiology KyivUkraine State Institute of genetic and Regenerative Medicine Kyiv Ukraine

The restricted neurogenesis limits the brain ability to overcome neuronal cell death following ischemic lesion：Failure of the damaged brain to regenerate following cerebral ischemia results in functional deficits those are most often irreversible and can further deteriorate,causing mortality and severe disability,progressive memory loss and cognitive impairments,known as dementia.

关键词： neurophysiological insights into stem progenitor cell neurogenesis within a host environment

Mathematical modeling of nanodispersed hardening of FCC materials

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Acta Metallurgica Sinica(English Letters) 2018年第12期31卷 1297-1304页

作者： Oleg Matvienko Olga Daneyko tatyana Kovalevskaya National Research Tomsk State University TomskRussia 634050 Tomsk State University of Architecture and Building TomskRussia 634003

The plastic deformation of the pipe made of Cu-based alloy hardened by incoherent nanoparticles and subjected to theuniform internal pressure was investigated. The limits of elastic and plastic resistance are determined. The insignificantexcess in the limit of the elastic resistance enables the plastic deformation in the most part of the pipe wall. The densities ofshear-forming dislocations and prismatic dislocation loops are higher in alloys strengthened with coarse particles than inalloys strengthened with fine particles. At small distances between the strengthening particles, this effect is the mostpronounced.

关键词： Deformation Dislocation Dispersion-strengthening - Nanoparticles Hardening Stress Strain Elastic-plastic deformation Pipe

Testing of new ionospheric models along the meridian 110°E over the Northern Hemisphere

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geodesy and geodynamics 2022年第6期13卷 544-553页

作者： Olga Maltseva Artem Kharakhashyan tatyana Nikitenko Institute for Physics Southern Federal University344090Russia

Despite the continuous improvement of the widely used empirical model international reference ionosphere(IRI),the recently appeared new models must be tested *** along the meridians has the advantage of dealing with the latitudinal dependent *** paper uses new models of parameters foF2(critical frequency),TEC(total electron content),andτ(equivalent slab thickness of the ionosphere),which are of great importance for evaluating the effects of space ***-Plas,NNT2F2,and NTSM models were tested using data from 6 ionosondes located along the meridian 110°E in March *** is shown that the IRI-Plas model provides the closest values to experiment with respect toτ,while the NTSM model provides a rather limited reflection of the latitude *** of foF2(NNT2F2)have shown that,the NNT2F2 model provides good conformity with experimental values in this area,but it is very dependent on the TEC processing *** latitudinal dependences of foF2 obtained with TEC and polynomial dependenceτ(Appr)showed the presence of positive deviations from medians not only during disturbances but also quiet periods,longitudinally at the meridian.

关键词： Ionosphere Modeling Total electron content Critical frequency Meridian 110°E

Fundamentals of Presbyopia: visual processing and binocularity in its transformation

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Eye and Vision 2018年第1期5卷 1-10页

作者： Olga I.Rozanova Andrey g.Shchuko tatyana S.Mischenko Irkutsk branch of S.Fyodorov Eye Microsurgery Federal State Institution IrkutskRussian Federation Irkutsk State Medical University IrkutskRussian Federation

Background:The accommodation has considerable interactions with the pupil response,vergence response and *** transformation of visual reception processing and the changes of the binocular cooperation during the presbyopia development are still poorly ***,the regularities of visual system violation in the presbyopia formation need to be *** study aims to reveal the transformation of visual reception processing and to determine the role of disturbances in binocular interactions in presbyopia ***:This study included 60 people with emmetropic refraction,uncorrected distance visual acuity 1.0 or higher(decimal scale),normal color perception,without concomitant *** first group consisted of 30 people(from 18 to 27 years old)without presbyopia,the second cohort comprised 30 patients(from 45 to 55 years old)with *** eyeball anatomy and optics were evaluated using ultrasound biomicroscopy,aberrometry,and *** functional state of the visual system was investigated under monocular and binocular *** registration of the disparate fusional reflex limits was performed by the original technic using a diploptic device which facilitated investigation of the binocular interaction under natural conditions without the accommodation response,but with the different vergence *** disparate fusional reflex was analyzed using the proximal and distal fusion borders,and the convergence and divergence fusion *** calculation of the area of binocularity field was performed in ***:The presbyopia formation is characterized by a change in an intraocular anatomy,optics,visual processing,and *** processes of binocular interaction inhibition make a significant contribution to the misalignment of the visual *** modification of the proximal,distal and convergence fusion borders was *** was revealed that 87%of the presbyopic patients had binocularity sh

关键词： Presbyopia Binocularity Visual processing Visual reception

Local inflammatory response to gastroesophageal reflux:Association of gene expression of inflammatory cytokines with esophageal multichannel intraluminal impedance-pH data

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World Journal of Clinical Cases 2022年第26期10卷 9254-9263页

作者： Sergey Morozov tatyana Sentsova Department of gastroenterology Hepatology and NutritionFederal Research Center of NutritionBiotechnology and Food SafetyMoscow 115446Russia Department of Hospital Pediatrics No.2 Russian National Research Medical University named after N.I.PirogovMoscow 117997Russia

BACKgROUND gene expression of inflammatory cytokines may take part in the pathophysiology of different forms of gastroesophageal reflux disease(gERD).AIM To explore gene expression of inflammatory cytokines in esophageal mucosa in patients with erosive esophagitis(EE)and non-erosive forms of gERD(NERD)and its association with data of esophageal multichannel intraluminal impedancepH(MII-pH)*** This was a single-center prospective *** mucosa samples were taken from the lower part of the esophagus during *** of interleukin(IL)-1β,IL-10,IL-18,tumor necrosis factorα(TNFA),toll-like receptor 4(TLR4),gATA binding protein 3(gATA3),differentiation cluster 68(CD68)andβ-2 microglobulin genes in esophageal mucosa was assessed with ImmunoQuantex ***-pH measurements were performed on all the *** of gERD was confirmed by the results of the MII-pH *** on the endoscopy,patients were allocated to the groups of EE and *** control group consisted of non-symptomatic subjects with normal endoscopy and MII-pH *** used nonparametric statistics to compare the differences between the *** of expression of the mentioned genes with the results of the MII-pH data was assessed with Spearman’s rank *** Data from 60 patients with gERD and 10 subjects of the control group were available for the *** expression of IL-18(5.89±0.4 vs 5.28±1.1,P=0.04)and gATA3(2.92±0.86 vs 2.23±0.96,P=0.03)was found in the EE group compared to *** of IL-1β,IL-18,TNFA,and TLR4 was lower(Pgroup compared to EE and *** acid exposure correlated with the expression of IL-1β(Spearman’s rank r=0.29),IL-18(r=0.31),TNFA(r=0.35),gATA3(r=0.34),TLR4(r=0.29),and CD68(r=0.37).Mean esophagealрНcorrelated inversely with the expression of IL-18,TNFA,gATA3,TLR4,and *** association of gene expression with the number of gastroesophageal refluxes was ***

关键词： gastroesophageal reflux disease gene expression Cytokines Erosive esophagitis Non-erosive gastroesophageal reflux disease Esophageal multichannel intraluminal impedance-pH gastroesophageal reflux

Mid-Miocene thermal impact on the lithosphere by sub-lithospheric convective mantle material:Transition from high-to moderate-Mg magmatism beneath Vitim Plateau,Siberia

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geoscience Frontiers 2017年第4期8卷 753-774页

作者： Irina Chuvashova Sergei Rasskazov tatyana Yasnygina Institute of the Earth's Crust Siberian Branch of RAS Irkutsk State University

High-Mg lavas are characteristic of the mid-Miocene volcanism in Inner *** the Vitim Plateau,small volume high-Mg volcanics erupted at 16-14 *** were followed with voluminous moderate-Mg lavas at 14-13 *** the former unit,we have recorded a sequence of（1） initial basaltic melts,contaminated by crustal material,（2） uncontaminated high-Mg basanites and basalts of transitional（K-Na-K） compositions,and（3） picrobasalts and basalts of K series;in the latter unit a sequence of（1） initial basalts and basaltic andesites of transitional（Na-K-Na） compositions and（2） basalts and trachybasalts of K-Na *** pressure estimation,we infer that the high-Mg melts were derived from the sublithospheric mantle as deep as 150 km,unlike the moderate-Mg melts that were produced at the shallow *** 14-13 Ma rock sequence shows that initial melts equilibrated in a garnet-free mantle source with subsequently reduced degree of melting garnet-bearing *** melting of relatively depleted lithospheric material,evidenced by mantle xenoliths,was involved in melting,*** suggest that the studied transition from high-to moderate-Mg magmatism was due to the mid-Miocene thermal impact on the lithosphere by hot sub-lithospheric mantle material from the Transbaikalian low-velocity（melting） domain that had a potential temperature as high as 1510℃.This thermal impact triggered rifting in the lithosphere of the Baikal Rift Zone.

关键词： Volcanism geodynamics Cenozoic Asia Asthenosphere Lithosphere