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Inverted Meckel's diverticulum preoperatively diagnosed using double-balloon enteroscopy

World Journal of Gastroenterology 2016年第17期22卷 4416-4420页

作者： Kosuke Takagaki Satoshi Osawa tatsuhiro ito Moriya Iwaizumi Yasushi Hamaya Hiroe Tsukui Takahisa Furuta Hidetoshi Wada Satoshi Baba Ken Sugimoto First Department of Medicine Hamamatsu University School of Medicine Department of Endoscopic and Photodynamic Medicine Hamamatsu University School of Medicine Department of Diagnostic Pathology Hamamatsu University School of Medicine Center for Clinical Research Hamamatsu University School of Medicine First Department of Surgery Hamamatsu University School of Medicine

An inverted Meckel’s diverticulum is a rare gastrointestinal congenital anomaly that is difficult to diagnose prior to surgery and presents with anemia, abdominal pain, or intussusception. Here, we report the case of 57-year-old men with an inverted Meckel’s diverticulum, who was preoperatively diagnosed using double-balloon enteroscopy. He had repeatedly experienced epigastric pain for 2 mo. Ultrasonography and computed tomography showed intestinal wall thickening in the pelvis. Double-balloon enteroscopy via the anal route was performed for further examination, which demonstrated an approximately 8-cm, sausage-shaped, submucosal tumor located approximately 80 cm proximal to the ileocecal valve. A small depressed erosion was observed at the tip of this lesion. Forceps biopsy revealed heterotopic gastric mucosa. Thus, the patient was diagnosed with an inverted Meckel’s diverticulum, and single-incision laparoscopic surgery was performed. This case suggests that an inverted Meckel’s diverticulum should be considered as a differential diagnosis for a submucosal tumor in the ileum. Balloon-assisted enteroscopy with forceps biopsy facilitate a precise diagnosis of this condition.

关键词： Inverted Meckel’ s diverticulum Double-balloon enteroscopy Small bowel tumor Epigastric pain Heterotopic gastric mucosa

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Comparison of fecal calprotectin levels and endoscopic scores for predicting relapse in patients with ulcerative colitis in remission

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World Journal of Gastroenterology 2023年第47期29卷 6111-6121页

作者： Natsuki Ishida tatsuhiro ito Kenichi Takahashi Yusuke Asai Takahiro Miyazu Tomohiro Higuchi Satoshi Tamura Shinya Tani Mihoko Yamade Moriya Iwaizumi Yasushi Hamaya Satoshi Osawa Ken Sugimoto Department of Endoscopic and Photodynamic Medicine Hamamatsu University of School of MedicineHamamatsu 431-3192Japan First Department of Medicine Hamamatsu University of School of MedicineHamamatsu 431-3192Japan Department of Laboratory Medicine Hamamatsu University of School of MedicineHamamatsu 431-3192Japan

BACKGROUND Although the usefulness of endoscopic scores,such as the Mayo Endoscopic Subscore(MES),Ulcerative Colitis Endoscopic Index of Severity(UCEIS),and Ulcerative Colitis Colonoscopic Index of Severity(UCCIS),and biomarkers such as fecal calprotectin(FC)for predicting relapse in ulcerative colitis(UC)has been reported,few studies have included endoscopic scores for evaluating the entire *** To compare the usefulness of FC value and MES,UCEIS,and UCCIS for predicting relapse in patients with UC in clinical *** In total,75 patients with UC in clinical and endoscopic remission who visited our institution between February 2019 and March 2022 were *** diagnosis of UC was confirmed based on the clinical presentation,endoscopic findings,and histology,according to the current established criteria for *** samples were collected the day before or after the colonoscopy for measurement of *** evaluations were performed using MES,UCEIS,and *** primary outcome measure of this study was the assessment of the association between relapse within 12 mo and MES,UCEIS,UCCIS,and *** secondary outcome was the comparison between endoscopic scores and biomarkers in en-rolled patients with UC with mucosal *** and UCCIS showed a significant correlation with UCEIS (r = 0.537, P < 0.001 and r = 0.957, P < 0.001, respectively).Receiver-operating characteristic analysis for predicting MES 0 showed that the area under the curve ofUCCIS was significantly higher than that of FC (P < 0.01). During the 1-year observation period, 18 (24%) patientsexperienced a relapse, and both the FC and UCCIS of the relapse group were significantly higher than that of theremission group. The cut-off values for predicting relapse were set at FC = 323 mg/kg and UCCIS = 10.2. The areaunder the curve of the receiver-operating characteristic analysis for predicting relapse did not show a significantdifference between FC and UCCIS. The accuracy of the

关键词： Ulcerative colitis Mayo Endoscopic Subscore Ulcerative Colitis Endoscopic Index of Severity Ulcerative Colitis Colonoscopic Index of Severity Fecal calprotectin Relapse

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