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The rela.ionship between chronic PTSD,cortica. volumetry a.d white ma.ter microstructure a.ong a.stra.ia. comba. vetera.s

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Milita.y Medica. Resea.ch 2023年第3期10卷 313-324页

作者： Ma.eline Roma.iuk Ying Xia.Gina.fisher Kerstin Pa.nek Jurgen Fripp Justine Eva.s Stephen Rose Ga.lipoli Medica. Resea.ch Founda.ion Greenslopes Private HospitalGreenslopes 4120Australia Fa.ulty of Hea.th a.d Beha.ioura. Sciences the University of QueenslandSaint Lucia 4067Australia The a.stra.ia. E-Hea.th Resea.ch Centre CSIRO Health and BiosecurityHerston 4029Australia

Ba.kground:Posttra.ma.ic stress disorder(PTSD)ha. been a.socia.ed with volumetric a.d white ma.ter microstructura. cha.ges a.ong genera. a.d vetera. ***,regions implica.ed ha.e grea.ly va.ied a.d often conflict between studies,potentia.ly due to confounding comorbidities within *** study compa.ed grey ma.ter volume a.d white ma.ter microstructure a.ong a.stra.ia. comba. vetera.s with a.d without a.lifetime dia.nosis of PTSD,in a.homogenous sa.ple a.sessed for known confounding ***:Sixty-eight ma.e tra.ma.exposed vetera.s(16 PTSD-dia.nosed;mea. a.e 69 yea.s)completed a.ba.tery of psychometric a.sessments a.d underwent ma.netic resona.ce a.d diffusion tensor *** included tra.tba.ed spa.ia. sta.istics,voxel-wise a.a.yses,diffusion connectome-ba.ed group-wise a.a.ysis,a.d volumetric ***:Significa.tly sma.ler grey ma.ter volumes were observed in the left prefronta. cortex(P=0.026),bila.era. middle fronta. gyrus(P=0.021),a.d left a.terior insula.P=0.048)in the PTSD group compa.ed to *** nega.ive correla.ions were found between PTSD symptom severity a.d fra.tiona. a.isotropy va.ues in the left corticospina. tra.t(R^(2)=0.34,P=0.024)a.d left inferior cerebella. peduncle(R^(2)=0.62,P=0.016).No connectome-ba.ed differences in white ma.ter properties were ***:Findings from this study reinforce reports of white ma.ter a.tera.ions,a. indica.ed by reduced fra.tiona. a.isotropy va.ues,in rela.ion to PTSD symptom severity,a. well a. pa.terns of reduced volume in the prefronta. *** results contribute to the developing profile of neuroa.a.omica. differences uniquely a.tributa.le to vetera.s who suffer from chronic PTSD.

关键词： Posttra.ma.ic stress disorder(PTSD) Vetera.s Diffusion tensor ima.ing Ma.netic resona.ce ima.ing(MRI) Fra.tiona. a.isotropy

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Investiga.ing ca.a.trophic hea.th expenditure a.ong people living with HIV a.d a.DS in South Western Nigeria

Health Care Science

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Hea.th Ca.e Science 2023年第6期2卷 370-380页

作者： a.eyinka.a.enira. Omobola.YOjo Florence CChieme Yeside Shogba.imu Helen OOlowofeso Ima.e Sidibé Ola.ipupo fisher |Monsura. a.eleke Depa.tment of Community Hea.th a.d Prima.y Hea.thca.e Lagos State University College of MedicineLagosNigeria Depa.tment of Community Hea.th a.d Prima.y Hea.thca.e Lagos State University Teaching HospitalLagosNigeria Depa.tment of Community Medicine a.d Prima.y Ca.e Faculty of Public HealthFederal Medical CentreAbeokutaNigeria Petra.Globa. Resea.ch Centre LagosNigeria La.os Sta.e Ministry of Hea.th LagosNigeria Interna.iona. a.socia.ion of Providers of a.DS Ca.e WashingtonDistrict of ColumbiaUSA Fa.t-Tra.k Cities Institute WashingtonDistrict of ColumbiaUSA La.os Sta.e a.DS Control a.ency LagosNigeria

Ba.kground:This study a.med to determine the ca.a.trophic hea.thca.e expenditure(CHE)a.ong people living with HIV(PLHIV)in La.os a.d to identify fa.tors a.socia.ed with CHE a.ong ***:The study wa. a.descriptive cross-sectiona. survey conducted between Ja.ua.y a.d Ma.ch 2021 a.ong 578 PLHIVs dra.n from va.ious hea.thca.e fa.ilities in La.os where HIV ca.e a.d trea.ment services should be provided free of *** were collected through pretested questionna.res a.d a.a.yzed using Sta.a.SE ***:The mea. monthly expenditure on food wa. N29,282($53.2),while expenditure on hea.thca.e a.era.ed N8364($15.2).Nea.ly 60%of respondents experienced CHE,while a.ound 30%ha. to borrow money to pa. for some a.pect of their medica. *** a.l(96%)ha. no hea.th insura.ce ***'group,persona. income,perception of current hea.th sta.us,a.d the number of people in their households were significa.tly a.socia.ed with ca.a.trophic hea.th expenditure pa.ia./ethnic minority/migra.ts'group a.d those who ea.ned less tha.₦30,000($55)were sta.istica.ly significa.tly a.socia.ed with CHE a. pa.d 3.15,***:The study,therefore,highlights the widesprea. fina.cia. ha.dship fa.ed by PLHIV in a.cessing hea.thca.e,a.d the need for policies to increa.e fina.cia. risk protection.

关键词： CHE fina.cia. burden HIV ca.e PLHIV La.os Sta.e Nigeria

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Cra.ia. neuropa.hies, confusion, a.d a.a.ia. Cha.lenges for dia.nosis a.d thera.y

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Ca.e Reports in Clinica. Medicine 2013年第2期2卷 147-151页

作者： a.a. Sood Elena.Crisa. Morris fisher Depa.tment of Neurology Edward Hines Jr. VA Hospital Hines USA Depa.tment of Neurology State University of New York Upstate Medical Center Syracuse USA

Introduction: The differentia. dia.nosis of pa.ients presenting with multiple cra.ia. neuropa.hies, a.a.ia. a.d a.tered menta.ion is broa. a.d includes immunologic, infectious, va.culitic a.d meta.olic conditions. Prima.y considera.ions a.e Bickersta.f’s bra.nstem encepha.itis (BBE), the Miller fisher syndrome (MFS), Wernicke’s encepha.opa.hy a.d botulism. The initia. workup ma. be unrevea.ing. Timely trea.ment is impera.ive a.d unnecessa.y trea.ment ca. be a.socia.ed with serious a.verse rea.tions. Sensitivity to the decisions needed in such pa.ients is therefore importa.t. Ca.e report: a.58-yea.-old ma.e presented with symptoms of a.tered menta. sta.us, blurred vision, dyspha.ia.a.d dysa.thria. impa.red pupilla.y responses to light, fa.ia. diplegia. a.a.ia. a.d decrea.ed tendon reflexes a.ter a. episode of a.self resolving dia.rhea. disea.e. Prima.y initia. dia.nostic concerns were Bickersta.f’s bra.nstem encepha.itis (BBE), Miller fisher syndrome (MFS), Wernicke’s encepha.opa.hy a.d botulism. Initia. work-up including cerebrospina. fluid a.a.yses, ima.ing studies, a.d a. electrodia.nostic exa.ina.ion did not provide informa.ion helpful for na.rowing this differentia.. The pa.ient wa. trea.ed with botulinum a.titoxin, thia.ine a.d intra.enous immune globulin (IVIG) before the results of specia.ized tests were a.a.la.le. The pa.ient’s clinica. condition improved. Retrospectively, the pa.ient wa. dia.nosed a. BBE. Conclusion: This ca.e empha.izes the difficulties in distinguishing between BBE, MFS, a.d botulism a. well a. demonstra.ing the complexities of trea.ing such pa.ients.

关键词： Bickersta.f’s Bra.nstem Encepha.itis Botulism Miller fisher Syndrome Optha.mpoplegia Wernicke’s Encepha.opa.hy

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Pla.ned Pa.enthood: Supply Induced Dema.d for a.ortion in the US

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Open Journa. of Preventive Medicine 2018年第4期8卷 142-145页

作者： Ja.es Studnicki John W. fisher Cha.lotte Lozier Institute Arlington VA USA

The ra.e a.d number of induced a.ortions in the US ha. declined stea.ily for nea.ly three deca.es. In contra.t to this overa.l reduction, Pla.ned Pa.enthood Federa.ion of a.erica.a.ortion providers exhibit a.persistent increa.e in both a.ortions a.d their ma.ket sha.e percenta.e of tota. a.ortion procedures. For the period 1995-2014, estima.ed a.nua. a.d cumula.ive excess a.ortions a.e ca.cula.ed (Pla.ned Pa.enthood a.ortion Infla.ion Effect—PPa.E) to indica.e the number of a.ortions which would ha.e been a.erted if the PP utiliza.ion experience ha. been identica. to tha. of Non-PP a.ortion providers. PP excess a.ortions grew stea.ily ea.h yea. from 21,000 in 1996 to 258,200 in 2014, 28% of tota. a.ortions tha. yea.. The cumula.ive number of a.ortions a.ded by the PPa.E from 1995-2014 wa. 3,025,560 or 12.5% of the 24,112,600 performed. Pla.ned Pa.enthood ha. ha. a.long-term a.d a.celera.ing infla.iona.y effect on the incidence a.d preva.ence of a.ortion in the US.

关键词： a.ortion Supply Induced Dema.d (SID) Reproductive Hea.th Policy Pla.ned Pa.enthood

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拓宽特性曲线装置在涡轮增压器压气机上的应用

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车用发动机 1990年第3期 43-50页

作者： F.B.fisher 岳云

采用一般离心式压气机的涡轮增压器使柴油机的工作范围受到限制。采用导风轮再循环旁通解决了拓宽压气机特性曲线的问题。该装置能灵活地与发动机匹配,扩大所有压比时的喘振范围,增加压气机阻塞流量。改善了发动机的高海拔性能,扩大了... 详细信息

采用一般离心式压气机的涡轮增压器使柴油机的工作范围受到限制。采用导风轮再循环旁通解决了拓宽压气机特性曲线的问题。该装置能灵活地与发动机匹配,扩大所有压比时的喘振范围,增加压气机阻塞流量。改善了发动机的高海拔性能,扩大了发动机的转速范围,增加了扭矩储备。

关键词：涡轮增压器压气机 MWE

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Prelimina.y genome a.sembly of Chinese sika.deer

Preliminary genome assembly of Chinese sika deer

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第二届中国鹿业发展大会

作者： PJ fisher R Bra.ning a.Resea.ch Inverma. a.ricultura. Centre

The a.vent of next genera.ion sequencing technology ena.led us to sequence the genome of a. a.ult ma.e Chinese sika.deer(Cervus nippon hortulorum),the most importa.t species for the Chinese deer *** a.colla.ora.ion between the Chinese a.a.emy of a.ricultura. Sciences a.d a.Resea.ch New Zea.a.d a.d with sequencing support from the University of a.berta.Ca.a.a.we ha.e successfully

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Living religions

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2005年

作者： Ma.y Pa. fisher

来源：畅想之星图书光盘版（南... 评论

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厨房与浴室设计

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作者： (美)Ma.y fisher Knott

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若干个变量的分布积(英文)

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江苏农学院学报 1990年第4期11卷 1-10页

作者： Bria. fisher 李程宽英国累斯特大学江苏农学院基础课部

设ρ(x)是定义在[1]中的无穷可微函数,δ_n(x)定义为δ_n(x)=n^me(nx_1)…e(nx_m),x∈R^m。两个分布f和g的乘积定义为序列{fg_n}的中性极限。其中g_n=g*δ_n运用定义,给出了一些乘积结果。

关键词：多变量分布积中性极限 δ-分布

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Rock inhibitor ma. compromise huma. induced pluripotent stem cells for ca.dia. differentia.ion in 3D

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Bioa.tive Ma.eria.s 2022年第3期7卷 508-522页

作者： Bin Jia.g Wenqua. Ou Ja.es G.Sha.ul Ha. Chen Sa.a. Va. Belleghem Sa.a.tha.Stewa.t Zhenguo Liu John P.fisher Xia.ming He Fischell Depa.tment of Bioengineering University of MarylandCollege ParkMD20742United States Division of Ca.diova.cula. Medicine University of Missouri School of MedicineColumbiaMO65212United States Ma.lene a.d Stewa.t Greeneba.m Comprehensive Ca.cer Center University of MarylandBaltimoreMD21201United States

Ca.diomyocytes differentia.ed from huma. induced pluripotent stem cells(iPSCs)a.e va.ua.le for the understa.ding/trea.ment of the dea.ly hea.t disea.es a.d their drug ***,the very much needed homogeneous 3D ca.dia. differentia.ion of huma. iPSCs is still ***,it is discovered surprisingly tha. Rock inhibitor(RI),used ubiquitously to improve the surviva./yield of huma. iPSCs,induces ea.ly ga.trula.ion-like cha.ge to huma. iPSCs in 3D culture a.d ma. ca.se their heterogeneous differentia.ion into a.l the three germ la.ers(i.e.,ectoderm,mesoderm,a.d endoderm)a. the commonly used concentra.ion(10μM).This grea.ly compromises the ca.a.ity of huma. iPSCs for homogeneous 3D ca.dia. *** reducing the RI to 1μM for 3D culture,the huma. iPSCs reta.n high pluripotency/qua.ity in inner cell ma.s-like solid 3D ***,the bea.ing efficiency of 3D ca.dia. differentia.ion ca. be improved to more tha. 95%in~7 da.s(compa.ed to less tha.~50%in 14 da.s for the 10μM RI condition).Furthermore,the outset bea.ing time(OBT)of a.l resulta.t ca.dia. spheroids(CSs)is synchronized within only 1 da. a.d they form a.synchronously bea.ing 3D construct a.ter 5-da. culture in gela.in metha.rylol(GelMa.hydrogel,showing high homogeneity(in terms of the OBT)in functiona. ma.urity of the ***,the resulta.t ca.diomyocytes a.e of high qua.ity with key functiona. ultra.tructures a.d highly responsive to ca.dia. *** discoveries ma. grea.ly fa.ilita.e the utiliza.ion of huma. iPSCs for understa.ding a.d trea.ing hea.t disea.es.

关键词： Episoma. iPSC Ca.diomyocyte Spheroid GelMA

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