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A new low-cost sensing system for rapid ring estimation of woody plants to support tree management

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Information Processing in Agriculture 2020年第3期7卷 369-374页

作者： Bayu taruna Widjaja Putra Laboratory of Precision Agriculture and Geo-Informatics Faculty of Agricultural TechnologyJember UniversityJember 68121East JavaIndonesia

Continuous monitoring of the diameter and rings of woody plants is required to evaluate agroforestry products such as *** measurement is still widely used to monitor tree growth but it is *** addition,advanced equipment and software are available but they require technical skills and are costly for ***,we have developed a rapid and low-cost sensing system for estimating the diameters of woody *** apparatus includes a sensor and Internet of things(IoT)technology,which can be used under any network *** apparatus was tested with various trees and the results were compared with those obtained by manual *** findings using the newly developed system demonstrate a strong correlation(R2=0.99)with the manually performed *** rapid and low-cost diameter sensing system will be useful in the expansion of agroforestry sensing networks and beneficial to ***,the system will assist in informing foresters of potential problems in timely manner.

关键词： Tree allometry IoT Woody plants Sensing system Precision Agriculture Forestry Management

Acquired Chiari Malformation: Safety of Neuraxial Anesthesia?

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Open Journal of Anesthesiology 2013年第1期3卷 11-13页

作者： Twinkal P. Dalal taruna penmetcha Maria Torres Ramsis Ghaly John H. Stroger Jr. Hospital of Cook County Chicago USA

Chiari malformation is a congenital anomaly that primarily involves the downward displacement of the cerebellar tonsils through the foramen magnum and elongation of forth ventricle and lower brainstem. Patients with Chiari I (congenital or acquired) malformation are asymptomatic or may presents with neurologic signs and symptoms. It is always a question of safety of neuraxial anesthesia in these patients. There is potential risk of dural puncture that can initiate the neurologic symptoms or worsen the existing symptoms due to CSF leakage or tonsillar herniation. Other side, performance of neuraxial anesthesia can cause acquired Chiari I type malformation due to CSF leak and intracranial hypotension. We reviewed the case reports and articles regarding safety of neuraxial anesthesia in the setting of Congenital or Acquired Chiari malformation.

关键词： Chiari Malformation Neuraxial Anesthesia

Novel anti-diabetic agents in non-alcoholic fatty liver disease: a mini-review

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Hepatobiliary & Pancreatic Diseases International 2013年第6期12卷 584-588页

作者： Manhal Olaywi taruna Bhatia Sury Anand Shashideep Singhal Division of Gastroenterology and Hepatology The Brooklyn Hospital Center/New York Presbyterian Healthcare System Division of Digestive and Liver Diseases Columbia University Medical Center

BACKGROUND:Non-alcoholic fatty liver disease(NAFLD)encompasses a spectrum that ranges from simple steatosis to non-alcoholic steatohepatitis(NASH)and to *** recommended treatment for this disease includes measures that target obesity and insulin *** present review summarizes the role of newer anti-diabetic agents in treatment of *** SOURCES:PubMed,MEDLINE and Ovid databases were searched to identify human studies between January 1990and January 2013 using specified key *** studies that enrolled patients with a diagnosis of NAFLD or NASH and involved use of newer classes of anti-diabetic agents for a duration of at least 3 months were ***:Out of the screened articles,four met eligibility criteria and were included in our *** classes of newer anti-diabetic medications described were dipeptidyl peptidase IV inhibitors and glucagon-like peptide-1 ***:Liraglutide and Exenatide showed improvement in transaminases as well as histology in patients with *** showed improvement in transaminases but limited studies are there to access its effect on *** studies are needed to support use of newer anti-diabetic medications in patients with NAFLD.

关键词： non-alcoholic fatty liver disease non-alcoholic steatohepatitis anti-diabetic agents Sitagliptin Exenatide Liraglutide

Potential of transposon-mediated cellular reprogramming towards cell-based therapies

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World Journal of Stem Cells 2020年第7期12卷 527-544页

作者： Dharmendra Kumar taruna Anand Thirumala R Talluri Wilfried A Kues Animal Physiology and Reproduction Division ICAR-Central Institute for Research on BuffaloesHisar 125001India NCVTC ICAR-National Research Centre on EquinesHisar 125001India Equine Production Campus ICAR-National Research Centre on EquinesBikaner 334001India Friedrich-Loeffler-Institut Institute of Farm Animal GeneticsDepartment of BiotechnologyMariensee 31535Germany

Induced pluripotent stem(iPS)cells present a seminal discovery in cell biology and promise to support innovative treatments of so far incurable *** translate iPS technology into clinical trials,the safety and stability of these reprogrammed cells needs to be *** recent years,different non-viral transposon systems have been developed for the induction of cellular pluripotency,and for the directed differentiation into desired cell *** this review,we summarize the current state of the art of different transposon systems in iPS-based cell therapies.

关键词： Transposons Induced pluripotent stem cells Clinical applications Cellular reprogramming Cell-based therapy Genetic correction

Induced pluripotent stem cells: Mechanisms, achievements and perspectives in farm animals

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World Journal of Stem Cells 2015年第2期7卷 315-328页

作者： Dharmendra Kumar Thirumala R Talluri taruna Anand Wilfried A Kues Institute of Farm Animal Genetics Friedrich-Loeffler-Institute Animal Physiology and Reproduction Division Central Institute for Research on Buffaloes National Research Centre on Equines

Pluripotent stem cells are unspecialized cells withunlimited self-renewal, and they can be triggered to differentiate into desired specialized cell types. These features provide the basis for an unlimited cell source for innovative cell therapies. Pluripotent cells also allow to study developmental pathways, and to employ them or their differentiated cell derivatives in pharmaceutical testing and biotechnological applications. Via blastocyst complementation, pluripotent cells are a favoured tool for the generation of genetically modified mice. The recently established technology to generate an induced pluripotency status by ectopic co-expression of the transcription factors Oct4, Sox2, Klf4 and c-Myc allows to extending these applications to farm animal species, for which the derivation of genuine embryonic stem cells was not successful so far. Most induced pluripotent stem(i PS) cells are generated by retroviral or lentiviral transduction of reprogramming factors. Multiple viral integrations into the genome may cause insertional mutagenesis and may increase the risk of tumour formation. Non-integration methods have been reported to overcome the safety concerns associated with retro and lentiviral-derived i PS cells, such as transient expression of the reprogramming factors using episomal plasmids, and direct delivery of reprogramming m RNAs or proteins. In this review, we focus on the mechanisms of cellular reprogramming and current methods used to induce pluripotency. We also highlight problems associated with the generation of i PS cells. An increased understanding of the fundamental mechanisms underlying pluripotency and refining the methodology of i PS cell generation will have a profound impact on future development and application in regenerative medicine and reproductive biotechnology of farm animals.

关键词： Reprogramming Large animal models Stemness Chimera Germline transmission Inducedpluripotent stem cells Gene delivery

Using information from images for plantation monitoring: A review of solutions for smallholders

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Information Processing in Agriculture 2020年第1期7卷 109-119页

作者： Bayu taruna Widjaja Putra Peeyush Soni Bambang Marhaenanto Pujiyanto Soni Sisbudi Harsono Spyros Fountas Laboratory of Precision Agriculture and Geoinformatics Faculty of Agricultural TechnologyJember UniversityJember 68121East JavaIndonesia Indonesian Coffee and Cocoa Research Institute(ICCRI) JemberEast JavaIndonesia Department of Agricultural and Food Engineering Indian Institute of Technology KharagpurKharagpur 721302India Agricultural University of Athens Iera Odos 7511845 AthensGreece

Technologically empowering farmers/smallholders notably accelerates the knowledge transfer to monitor plantations in developing ***,cost-effective technologies can rapidly increase the effectiveness of using expenses,labor,and *** is no limit to using digital cameras for non-destructive measurements,such as nutrient monitoring,pests and diseases,yield monitoring,and other information related to individual plant conditions in the plantation *** paper elaborates the fundamental concepts and best practices for future research on how to use image information from a single digital camera in decision support systems as a solution to monitoring plantations such as coffee,cocoa,and tree *** paper reviews the recent and potential research on plantation monitoring using a digital camera and other suitable integrated ***,we propose a protocol for use as a possible solution for smallholders to cope with the limitation in network/internet access *** this protocol,an integrated system for monitoring the farm activities of smallholders can be established.

关键词： Camera Sensors DSS protocol Biophysical monitoring Plantation monitoring

The Art of Oncoimmunovaccinomics

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World Journal of Vaccines 2021年第4期11卷 50-66页

作者： taruna Ikrar Dito Anurogo Chairman of Medical Council The Indonesian Medical Council Jakarta Aivita Biomedical Inc. Irvine California Department of Pharmacology Faculty of Medicine Malahayati University Bandar Lampung International PhD Program for Cell Therapy and Regeneration Medicine (IPCTRM) College of Medicine Taipei Medical University (TMU) Taipei City Faculty of Medicine and Health Sciences Universitas Muhammadiyah Makassar Makassar

The art of oncoimmunovaccinomics will be concisely explained herein. This scientific insight will explore its history cancer immunotherapy, the molecular basis of cancer immunotherapy, cancer immunotherapeutic approach, cancer immunosurveillance and immunoediting, the hallmarks of cancer (can be) revisited, nanotechnology-based cancer immunotherapy, immunovaccinomics, vaccinomics approach, the theory of vaccinology, adversomics, and immunogenomic perspectives.

关键词： Oncology Cancer Immunotherapy Nanoparticles Immunovaccinomics Vaccinology Adversomics

Presurgical Nasoalveolar Moulding—An Adjunct to Facilitate Surgical Repair in Infants with Cleft Lip and Palate

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Modern Plastic Surgery 2013年第1期3卷 34-42页

作者： Dolly Patel Ramesh Goyal taruna Puri Department of Orthodontics and Dentofacial Orthopaedics Government Dental College and Hospital Ahmedabad India

Presurgical orthopedics forms an integral part of the treatment of patients with facial clefting. The primary aim of presurgical nasoalveolar moulding (PNAM) is reduction in the soft tissue and cartilaginous deformity to facilitate surgical soft tissue repair in optimal conditions under minimum tension to minimize scar formation. It also helps in reducing the nasal deformity with a nasal stent which brings the deformity near to the normal and forms an important part of the primary nasal repair at the time of primary lip repair. A soft acrylic relining material is added or removed to line the appliance to a thickness of approximately 1 - 1.5 mmin the region from where the bone is to be resorbed or apposed. This article describes the fabrication procedure of the modified nasal alveolar molding appliance in eight infants with unilateral cleft lip and palate in whom a significant reduction in cleft width and nasoalveolar deformity was achieved. The results showed that the greater segment shows more favourable changes and can be molded more positively and efficiently than the lesser segment.

关键词： PNAM Nasal Stent Pre-Surgical Orthopaedics

Trend Analysis of Three Major Mosquito Borne Diseases in Punjab, India

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Journal of Biosciences and Medicines 2020年第5期8卷 1-11页

作者： Gagandeep Singh Grover Jaspreet Takkar taruna Kaura Seema Devi Naveed Pervaiz Upninder Kaur Rakesh Sehgal National Vector Borne Disease Control Programme Chandigarh Punjab India Department of Physiology Gian Sagar Medical College Punjab India Department of Medical Parasitology PGIMER Chandigarh India Department of Zoology Panjab University Chandigarh India

Background & Objectives: Understanding the distribution and prevalence of three major mosquito borne diseases in an area is critical for the development of effective vector control strategies and public health interventions. The present study is therefore aimed to explore the epidemiological trend of malaria, dengue and chikungunya from 2012 to 2018 in Punjab. Methods: Quantitatively retrospective data was collected from Department of Health and Family Welfare, the National Vector Borne Disease Control Programme (NVBDCP), Punjab from 2012 to March 2018. The collected data was statistically analysed. Results: In case of malaria highest prevalent districts in Punjab are Mansa and Bathinda, for dengue Patiala, Ludhiana and S.A.S. Nagar and Patiala for chikungunya. Malaria was reported mainly from rural areas while dengue and chikungunya were found more in urban areas. For all three mosquito borne diseases, males were infected more as compared to females. Malaria cases were reported in months of August and September while dengue cases increased from July to November whereas chikungunya cases were highest in months of August to October. Conclusions: These findings help in concluding the trend analysis which in turn helps us to increase our focus on disease endemic districts along with boosting the vector control strategies in respective districts. Further the control of these mosquito borne diseases can be solved by employing adequate human resources, by increasing awareness in the community by conducting health camps and strengthening the entomological surveillance for timely reduction in the breeding of the vectors, especially before the repeated rise in cases during the period from July to November each year.

关键词： NVBDCP Malaria Dengue Chikungunya